Citation Impact
Citing Papers
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing.
1995
Structure and function of an RNase H domain at the heart of the spliceosome
2008
Role of monocarboxylate transporters in human cancers: state of the art
2012
Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things
1998
The group II intron ribonucleoprotein precursor is a large, loosely packed structure
2010 StandoutNobel
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
1998
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
2008 StandoutNature
Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination
2003 StandoutNobel
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome
2008
Photocross-Linking of Nucleic Acids to Associated Proteins
1997
Myeloid-related Protein (MRP) 8 and MRP14, Calcium-binding Proteins of the S100 Family, Are Secreted by Activated Monocytes via a Novel, Tubulin-dependent Pathway
1997
Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae
1999
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
2001 StandoutNature
A Putative Mammalian RNA Helicase with an Arginine-Serine-rich Domain Colocalizes with a Splicing Factor
1995 StandoutNobel
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
PSF and p54nrb/NonO – multi‐functional nuclear proteins
2002
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Suppression of Multiple Substrate Mutations by Spliceosomal prp8 Alleles Suggests Functional Correlations with Ribosomal Ambiguity Mutants
2004
Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p
2006
Fundamental Cellular Processes Do Not Require Vertebrate-specific Sequences within the TATA-binding Protein
2003 StandoutNobel
Defining a 5??? splice site by functional selection in the presence and absence of U1 snRNA 5??? end
2002
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants
2006 StandoutNobel
Is the spliceosome a ribonucleoprotein enzyme?
2008
Composition and Functional Characterization of the Yeast Spliceosomal Penta-snRNP
2002
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
2000 Nature
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
The question remains: is the spliceosome a ribozyme?
2000
Pyruvate kinase type M2 and its role in tumor growth and spreading
2005
Protein functions in pre-mRNA splicing
1997
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
2001
Site-specific crosslinking of human microRNPs to RNA targets
2008
A novel pseudoknot element is essential for the action of a yeast telomerase
2003 StandoutNobel
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Functional interaction of a novel 15.5kD [U4/U6middle dotU5] tri-snRNP protein with the 5' stem-loop of U4 snRNA
1999
Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center
1999
The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site
2001
Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complex
1999 StandoutNobel
An RNA Switch at the 5′ Splice Site Requires ATP and the DEAD Box Protein Prp28p
1999
RNA helicases: modulators of RNA structure
1994
Spliceosomal snRNA modifications and their function
2010
The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes
2018 StandoutNobel
The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC
1997 StandoutNobel
Isolation of an active step I spliceosome and composition of its RNP core
2008 Nature
[2] Methylene blue-mediated cross-linking of proteins to double-stranded RNA
2000
The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H Box ATPase
2006
Spliceosomal immunophilins
2008
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Spliceosomal UsnRNP biogenesis, structure and function
2001
The SR protein family
2009
Splicing enhancement in the yeast rp51b intron
2000 StandoutNobel
Expansion of the eukaryotic proteome by alternative splicing
2010 StandoutNature
An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2
1997
Specific Alterations of U1-C Protein or U1 Small Nuclear RNA Can Eliminate the Requirement of Prp28p, an Essential DEAD Box Splicing Factor
2001
Functional Anatomy of a dsRNA Trigger
2000 StandoutNobel
Repositioning of the Reaction Intermediate within the Catalytic Center of the Spliceosome
2006
Crystal Structure of a Complex Between Human Spliceosomal Cyclophilin H and a U4/U6 snRNP-60K Peptide
2003
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
2000
Cotranscriptional Spliceosome Assembly Dynamics and the Role of U1 snRNA:5′ss Base Pairing in Yeast
2005 StandoutNobel
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
The 65 and 110 kDa SR-related proteins of the U4/U6U5 tri-snRNP are essential for the assembly of mature spliceosomes
2001
Functional Recognition of the 5′ Splice Site by U4/U6.U5 tri-snRNP Defines a Novel ATP-Dependent Step in Early Spliceosome Assembly
2000
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Splicing of a rare class of introns by the U12-dependent spliceosome
2005
Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila
2011 StandoutNobel
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
SR Proteins and Related Factors in Alternative Splicing
2007
Characterization of U4 and U6 interactions with the 5′ splice site using a S. cerevisiae in vitro trans-splicing system
2001
Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection
1999
Structural elucidation of a PRP8 core domain from the heart of the spliceosome
2008
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6middle dotU5] tri-snRNP
1999
A role for a novel ‘trans-pseudoknot’ RNA–RNA interaction in the functional dimerization of human telomerase
2003 StandoutNobel
Calcium Signaling
2007 Standout
A Conformational Rearrangement in the Spliceosome Sets the Stage for Prp22-Dependent mRNA Release
2008
Prp8 protein: At the heart of the spliceosome
2005
Specific telomerase RNA residues distant from the template are essential for telomerase function
1998 StandoutNobel
Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)
2008
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
2010 Standout
Proteomics to study genes and genomes
2000 StandoutNature
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
2009 StandoutNobel
A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae
2000 StandoutNature
ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8
2008
The myeloic related protein MRP8/14 (27E10 antigen)— usefulness as a potential marker for disease activity in ulcerative colitis and putative biological function
1995
Phosphorylation Drives a Dynamic Switch in Serine/Arginine-Rich Proteins
2013
The network of protein–protein interactions within the human U4/U6.U5 tri-snRNP
2006
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes
2004 StandoutNobel
Structure, Reactivity, and Biology of Double-Stranded RNA
1996
A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro
1999
RAGE Mediates a Novel Proinflammatory Axis
1999 Standout
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure
1998
Purification and electron microscopic visualization of functional human spliceosomes
2002
A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.
1998 StandoutNobel
Spliceosome Activation by PRP2 ATPase prior to the First Transesterification Reaction of Pre-mRNA Splicing
1996
A U1/U4/U5 snRNP Complex Induced by a 2′- O -Methyl-Oligoribonucleotide Complementary to U5 snRNA
1996 Science
The U1 snRNP Base Pairs with the 5′ Splice Site within a Penta-snRNP Complex
2003
Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
1999
The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome
2002
Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation
2015
Mass spectrometry-based proteomics
2003 StandoutNature
Primary structure and binding properties of calgranulin C, a novel S100-like calcium-binding protein from pig granulocytes.
1994
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Structure of a Multipartite Protein-Protein Interaction Domain in Splicing Factor Prp8 and Its Link to Retinitis Pigmentosa
2007
Nuclear Translocation of the Tumor Marker Pyruvate Kinase M2 Induces Programmed Cell Death
2007
A cyclophilin functions in pre-mRNA splicing
2002
Identification of Proteins That Interact with Exon Sequences, Splice Sites, and the Branchpoint Sequence during Each Stage of Spliceosome Assembly
1996
Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction
2000
Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins
1999
Polymerization Defects within Human Telomerase Are Distinct from Telomerase RNA and TEP1 Binding
2000
Allosteric Cascade of Spliceosome Activation
2002
Identification of RNA Binding Proteins by UV Cross‐Linking
2003
The canonical GU dinucleotide at the 5' splice site is recognized by p220 of the U5 snRNP within the spliceosome.
1996
PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator
2005 StandoutScienceNobel
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation
2004 StandoutNobel
Proteomics Analysis Reveals Stable Multiprotein Complexes in Both Fission and Budding Yeasts Containing Myb-Related Cdc5p/Cef1p, Novel Pre-mRNA Splicing Factors, and snRNAs
2002
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
p68 RNA Helicase Is an Essential Human Splicing Factor That Acts at the U1 snRNA-5′ Splice Site Duplex
2002
Calcium-dependent and -independent interactions of the S100 protein family
2006
Works of Stefan Teigelkamp being referenced
Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing
1995
Complex pattern of the myelo-monocytic differentiation antigens MRP8 and MRP14 during chronic airway inflammation
1992
The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNA.
1994
The pyruvate kinase isoenzyme tumor M2 (Tu M2-PK) as a tumor marker for renal carcinoma.
1999
The Human U5-220kD Protein (hPrp8) Forms a Stable RNA-Free Complex with Several U5-Specific Proteins, Including an RNA Unwindase, a Homologue of Ribosomal Elongation Factor EF-2, and a Novel WD-40 Protein
1998
Tumor M2-PK and glutaminolytic enzymes in the metabolic shift of tumor cells.
2001
The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p.
1997
Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.
1995
snRNA interactions at 5' and 3' splice sites monitored by photoactivated crosslinking in yeast spliceosomes.
1995
Calcium-dependent complex assembly of the myeloic differentiation proteins MRP-8 and MRP-14
1991
The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases.
1996
The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins.
1998
The role of PRP8 protein in nuclear pre-mRNA splicing in yeast
1995