Citation Impact
Citing Papers
Halogen bonds in biological molecules
2004 Standout
Tryptophan 7-Halogenase (PrnA) Structure Suggests a Mechanism for Regioselective Chlorination
2005 Science
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains
2016
Subpolar addition of new cell wall is directed by DivIVA in mycobacteria
2014 StandoutNobel
Sequential Asymmetric Polyketide Heterocyclization Catalyzed by a Single Cytochrome P450 Monooxygenase (AurH)
2008
The 1.92-Å Structure of Streptomyces coelicolor A3(2) CYP154C1
2003
New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan
2008
Biosynthesis of the Antitumor Agent Chartreusin Involves the Oxidative Rearrangement of an Anthracyclic Polyketide
2005
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
2013 StandoutNobel
Biphenyl synthase, a novel type III polyketide synthase
2006
Diversity of P450 enzymes in the biosynthesis of natural products
2012
The chalcone synthase superfamily of type III polyketide synthases
2002
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
2014 StandoutNature
Renaissance in antibacterial discovery from actinomycetes
2008
Total Synthesis of Complestatin (Chloropeptin II)
2010
Bacterial stress responses as determinants of antimicrobial resistance
2012
Combinatorial biosynthesis of reduced polyketides
2005
Natural‐Product Sugar Biosynthesis and Enzymatic Glycodiversification
2008
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Thiol Template Peptide Synthesis Systems in Bacteria and Fungi
1996
The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites
2005
The Science of Antibiotic Discovery
2020 Standout
Organocatalytic Enantioselective Decarboxylative Aldol Reaction of Malonic Acid Half Thioesters with Aldehydes
2013 StandoutNobel
The Oxidative Ring Cleavage in Jadomycin Biosynthesis: A Multistep Oxygenation Cascade in a Biosynthetic Black Box
2005
γ-Butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation
2006
Crystal Structure of OxyC, a Cytochrome P450 Implicated in an Oxidative C–C Coupling Reaction during Vancomycin Biosynthesis
2003
Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters
2014
Cytochrome P450 monooxygenases: perspectives for synthetic application
2006
Bacterial transglycosylase inhibitors
2005
Daptomycin-Mediated Reorganization of Membrane Architecture Causes Mislocalization of Essential Cell Division Proteins
2012
Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis
2008
The Neocarzinostatin Biosynthetic Gene Cluster from Streptomyces carzinostaticus ATCC 15944 Involving Two Iterative Type I Polyketide Synthases
2005
Organocatalytic Asymmetric Hydrolysis of Epoxides
2014 StandoutNobel
How pathogenic bacteria evade mammalian sabotage in the battle for iron
2006
A Gene Cluster from a Marine Streptomyces Encoding the Biosynthesis of the Aromatic Spiroketal Polyketide Griseorhodin A
2002
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Mutasynthesis‐Derived Myxalamids and Origin of the Isobutyryl‐CoA Starter Unit of Myxalamid B
2007
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Complex reactions catalyzed by cytochrome P450 enzymes
2006
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Biological dehalogenation and halogenation reactions
2003
Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
2005
A Type I/Type III Polyketide Synthase Hybrid Biosynthetic Pathway for the Structurally Unique ansa Compound Kendomycin
2008
Structure and function of “metalloantibiotics”
2003
Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering
2008
Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes
2006
Halogenation Strategies In Natural Product Biosynthesis
2008
Molecular engineering approaches to peptide, polyketide and other antibiotics
2006
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137
2007
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Biosynthesis and function of polyacetylenes and allied natural products
2008
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties
2007 StandoutNobel
Vancomycin Assembly: Nature's Way
2003
Conformational Plasticity and Structure/Function Relationships in Cytochromes P450
2010
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products
2010 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Ribosomal Synthesis of N-Methyl Peptides
2008 StandoutNobel
Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis
2011 StandoutNobel
Structure of Mammalian Cytochrome P450 2C5 Complexed with Diclofenac at 2.1 Å Resolution: Evidence for an Induced Fit Model of Substrate Binding,
2003
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Flavin-dependent halogenases involved in secondary metabolism in bacteria
2006
Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3
2006 StandoutNobel
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449
2005
Copper Active Sites in Biology
2014 Standout
Recent Advances in Transition Metal Catalyzed Oxidation of Organic Substrates with Molecular Oxygen
2005 Standout
Biosynthesis of the Vancomycin Group of Antibiotics: Involvement of an Unusual Dioxygenase in the Pathway to (S)-4-Hydroxyphenylglycine
2000
Biohalogenation: Nature’s Way to Synthesize Halogenated Metabolites
2009
Structural Aspects of Ligand Binding to and Electron Transfer in Bacterial and Fungal P450s
2004
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
Sampling the Antibiotic Resistome
2006 StandoutScience
Hydrogenases
2014 Standout
Development of Halogenase Enzymes for Use in Synthesis
2017
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
Engineered Cytochrome P450-Catalyzed Oxidative Biaryl Coupling Reaction Provides a Scalable Entry into Arylomycin Antibiotics
2022
Biosynthesis of the Iron-Guanylylpyridinol Cofactor of [Fe]-Hydrogenase in Methanogenic Archaea as Elucidated by Stable-Isotope Labeling
2012
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
Insight into the structure–function relationship of the nonheme iron halogenases involved in the biosynthesis of 4‐chlorothreonine – T hr3 from S treptomyces sp. OH ‐5093 and S yrB 2 from P seudomonas syringae pv. syringae B 301DR
2012 StandoutNobel
Pentalenolactone Biosynthesis. Molecular Cloning and Assignment of Biochemical Function to PtlI, a Cytochrome P450 of Streptomyces avermitilis
2006 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
2016 StandoutNobel
The Halogen Bond
2016 Standout
Nature's Inventory of Halogenation Catalysts: Oxidative Strategies Predominate
2006
Polyketide and Nonribosomal Peptide Antibiotics: Modularity and Versatility
2004 Science
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450 BM3 demethylases
2009 StandoutNobel
Cloning, Sequencing, and Functional Analysis of an Iterative Type I Polyketide Synthase Gene Cluster for Biosynthesis of the Antitumor Chlorinated Polyenone Neocarzilin in “ Streptomyces carzinostaticus ”
2004
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Ribosomal Synthesis of Unnatural Peptides
2005 StandoutNobel
Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse
2017
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Challenges of Antibacterial Discovery
2011
Genetics of Zwittermicin A Production by Bacillus cereus
2004
Proton-Coupled Electron Transfer
2012 Standout
Structure and Chemistry of Cytochrome P450
2005 Standout
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Sequential Asymmetric Polyketide Heterocyclization Catalyzed by a Single Cytochrome P450 Monooxygenase (AurH)
2008
Works of Stefan Pelzer being referenced
Production of 8′-Halogenated and 8′-Unsubstituted Novobiocin Derivatives in Genetically Engineered Streptomyces coelicolor Strains
2004
A general approach for cloning and characterizing dNDP-glucose dehydratase genes from actinomycetes
1996
The Biosynthesis of Vancomycin‐Type Glycopeptide Antibiotics—A Model for Oxidative Side‐Chain Cross‐Linking by Oxygenases Coupled to the Action of Peptide Synthetases
2005
Cloning and Heterologous Expression of the Aranciamycin Biosynthetic Gene Cluster Revealed a New Flexible Glycosyltransferase
2007
Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis
2002
The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics-The Order of the Cyclization Steps
2001
A Polyketide Synthase in Glycopeptide Biosynthesis
2001
Cloning and analysis of a peptide synthetase gene of the balhimycin producer Amycolatopsis mediterranei DSM5908 and development of a gene disruption/replacement system
1997
Exploiting the genetic potential of polyketide producing streptomycetes
2003
Bromobalhimycin and Chlorobromobalhimycins—Illuminating the Potential of Halogenases in Glycopeptide Antibiotic Biosyntheses
2003
The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics—New Insights into the Cyclization Steps
2001
Fluorobalhimycin—A New Chapter in Glycopeptide Antibiotic Research
2002
Precursor-Directed Biosynthesis for the Generation of Novel Glycopetides
2006
Identification and characterization of phosphinothricin-tripeptide biosynthetic genes in Streptomyces viridochromogenes
1992
Molecular Analysis of the Kirromycin Biosynthetic Gene Cluster Revealed β-Alanine as Precursor of the Pyridone Moiety
2008
A Genomic Screening Approach to the Structure‐Guided Identification of Drug Candidates from Natural Sources
2007
Glycopeptide Biosynthesis in Amycolatopsis mediterranei DSM5908
2002
New Advances in the Biosynthesis of Glycopeptide Antibiotics of the Vancomycin Type fromAmycolatopsis mediterranei
1999
Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules The GenBank/EMBL/DDBJ accession number for the balhimycin biosynthetic gene sequence reported in this paper is Y16952.
2002
Biosynthesis of Chloro-β-Hydroxytyrosine, a Nonproteinogenic Amino Acid of the Peptidic Backbone of Glycopeptide Antibiotics
2004
Identification and Analysis of the Balhimycin Biosynthetic Gene Cluster and Its Use for Manipulating Glycopeptide Biosynthesis in Amycolatopsis mediterranei DSM5908
1999
Daptomycin versus Friulimicin B: In-Depth Profiling of Bacillus subtilis Cell Envelope Stress Responses
2009
Die Biosynthese von Glycopeptid-Antibiotika des Vancomycin-Typs - neue Einblicke in die Abfolge der Ringschlüsse
2001
Biosynthese von Glycopeptid-Antibiotika vom Vancomycin-Typ: die Reihenfolge der Ringschlüsse
2001
Biosynthetic Gene Cluster of Simocyclinone, a Natural Multihybrid Antibiotic
2002
The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate
2009