Citation Impact
Citing Papers
Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity
2016
The gut microbiota influences blood-brain barrier permeability in mice
2014 Standout
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
The human brain endothelial cell line hCMEC/D3 as a human blood‐brain barrier model for drug transport studies
2008
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
2014
Guidelines for the welfare and use of animals in cancer research
2010 Standout
TEER Measurement Techniques for In Vitro Barrier Model Systems
2015 Standout
In vitro models of the blood-brain barrier
2011
Engineering precision nanoparticles for drug delivery
2020 Standout
Adrenomedullin regulates blood–brain barrier functions in vitro
2001
Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts
2004
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Contribution of Carrier-Mediated Transport Systems to the Blood–Brain Barrier as a Supporting and Protecting Interface for the Brain; Importance for CNS Drug Discovery and Development
2007
A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters
2007
Altered blood–brain barrier integrity in adult aquaporin-4 knockout mice
2008
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
2012
The Blood–Brain Barrier
2015 Standout
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
2007 Standout
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
2014 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Modelling the Neurovascular Unit and the Blood-Brain Barrier with the Unique Function of Pericytes
2011
In Vitro and In Vivo Methods for Assessing FcRn-Mediated Reverse Transcytosis Across the Blood–Brain Barrier
2011
Lead- and drug-like compounds: the rule-of-five revolution
2004 Standout
Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging
2013 Standout
Structure and function of the blood–brain barrier
2009 Standout
Brain development in rodents and humans: Identifying benchmarks of maturation and vulnerability to injury across species
2013 Standout
Embolic strokes of undetermined source: the case for a new clinical construct
2014 Standout
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
Drug-mediated toxicity: illuminating the ‘bad’ in the test tube by means of cellular assays?
2012
Neuroprotection for ischemic stroke: Past, present and future
2008
In vivo SELEX for Identification of Brain-penetrating Aptamers
2013
Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells
2017
NXY-059 for Acute Ischemic Stroke
2006
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer
2016 Standout
Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood–brain barrier
2004
A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
2008 Standout
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Quantitative targeted proteomics for understanding the blood–brain barrier: towards pharmacoproteomics
2014
Pharmacological approaches to acute ischaemic stroke: reperfusion certainly, neuroprotection possibly
2007
P‐glycoprotein in blood–brain barrier endothelial cells: interaction and oligomerization with caveolins
2003
Murine brain capillary endothelial cells exhibit improved barrier properties under the influence of hydrocortisone
2005
Comparison of Two Blood-Brain Barrier In Vitro Systems: Cytotoxicity and Transfer Assessments of Malathion/Oxon and Lead Acetate
2010
Development of the Nitrone‐Based Spin Trap Agent NXY‐059 to Treat Acute Ischemic Stroke
2003
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Direct Evidence That Polysorbate-80-Coated Poly(Butylcyanoacrylate) Nanoparticles Deliver Drugs to the CNS via Specific Mechanisms Requiring Prior Binding of Drug to the Nanoparticles
2003
Human astrocytes/astrocyte-conditioned medium and shear stress enhance the barrier properties of human brain microvascular endothelial cells
2007
Murine in vitro model of the blood–brain barrier for evaluating drug transport
2010
The blood-brain barrier: an engineering perspective
2013
Measuring reactive species and oxidative damagein vivoand in cell culture: how should you do it and what do the results mean?
2004 Standout
Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises
2011 Standout
Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier
2012
Aptamers as targeted therapeutics: current potential and challenges
2016 Standout
Stroke
2008 Standout
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Microfluidic organs-on-chips
2014 Standout
Growth-factor reduced Matrigel source influences stem cell derived brain microvascular endothelial cell barrier properties
2016
Tanshinone IIB, a primary active constituent from Salvia miltiorrhza, exhibits neuro-protective activity in experimentally stroked rats
2007
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke
2008 Standout
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
2019
Permeability Studies on In Vitro Blood–Brain Barrier Models: Physiology, Pathology, and Pharmacology
2005
Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery
2008
In silico prediction of blood–brain barrier permeation
2003
Development of a three-dimensional, all-human in vitro model of the blood–brain barrier using mono-, co-, and tri-cultivation Transwell models
2011
Nitrone-Related Therapeutics
2004
Role of the Blood–Brain Barrier in the Nutrition of the Central Nervous System
2014
The effect of astrocytes on the induction of barrier properties in aortic endothelial cells
2011
Small vessel disease: mechanisms and clinical implications
2019 Standout
Development of the blood-brain barrier
2003
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials
2010 Standout
Erythropoietin protects the in vitro blood–brain barrier against VEGF‐induced permeability
2003
Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches
2010
Oxidative stress and neurodegeneration: where are we now?
2006 Standout
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
The Pathobiology of Vascular Dementia
2013 Standout
In vitro models for the blood–brain barrier
2004
Puromycin‐based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood–brain barrier‐specific properties
2005
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
The blood-brain barrier: Bottleneck in brain drug development
2004 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
IgG Subclasses and Allotypes: From Structure to Effector Functions
2014 Standout
Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models
2004
Novel models for assessing blood–brain barrier drug permeation
2012
Potential Roles of HDAC Inhibitors in Mitigating Ischemia-induced Brain Damage and Facilitating Endogenous Regeneration and Recovery
2013
Guidelines for the Early Management of Adults With Ischemic Stroke
2007 Standout
Guidelines for the Early Management of Patients With Acute Ischemic Stroke
2013 Standout
Constituents from Salvia Species and Their Biological Activities
2012 Standout
Functional and Histological Evidence for the Protective Effect of NXY-059 in a Primate Model of Stroke When Given 4 Hours After Occlusion
2003
Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier
2018
In Vitro Models of the Blood–Brain Barrier for the Study of Drug Delivery to the Brain
2014
Prediction of Drug Absorption Using Multivariate Statistics
2000 Standout
Computational methods for the prediction of ‘drug-likeness’
2000
Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma
2013
The Therapeutic Potential of Apigenin
2019 Standout
1,500 scientists lift the lid on reproducibility
2016 StandoutNature
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
2012 Standout
Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties
2000 Standout
Drug delivery and nanoparticles: Applications and hazards
2008 Standout
Outcomes Validity and Reliability of the Modified Rankin Scale: Implications for Stroke Clinical Trials
2007 Standout
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Methotrexate Loaded Polyether-Copolyester Dendrimers for the Treatment of Gliomas: Enhanced Efficacy and Intratumoral Transport Capability
2008
Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations
2009 Standout
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Works of Stefan Lundquist being referenced
The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood–brain barrier in the pharmaceutical industry—Background and current status in the drug discovery process
2002
Prediction of Drug Transport Through the Blood-Brain Barrier in Vivo: A Comparison Between Two in Vitro Cell Models
2002
Brain penetration of the novel free radical trapping neuroprotectant NXY-059 in rats subjected to permanent focal ischemia
2006
Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates
2015
Modelling of the blood–brain barrier in drug discovery and development
2007
Transport Screening of Drug Cocktails Through an in Vitro Blood-Brain Barrier: Is It a Good Strategy for Increasing the Throughput of the Discovery Pipeline?
2004
Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitromodels of the rat blood-brain barrier and blood-spinal cord barrier
2013
An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening
2008
In vitro blood–brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions
2002
In vitro model for evaluating drug transport across the blood–brain barrier
1999