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Citing Papers
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Consensus statement * on the treatment of allergic rhinitis
2000
The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis.
1996
Bronchial responsiveness to distilled water and methacholine and its relationship to inflammation and remodeling of the airways in asthma.
1996
Formoterol and salbutamol inhibit bradykinin‐ and histamine‐induced airway microvascular leakage in guinea‐pig
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Comparison of ciliary activity and inflammatory mediator release from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients and the effect of diesel exhaust particles in vitro
1998
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1997
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
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Mediator and cytokine mechanisms in asthma.
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Purinergic Signaling in the Airways
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Genetics of susceptibitlity to human infectious disease
2001
Adenosine-induced bronchoconstriction and its inhibition by nedocromil sodium
1993
Clinical Pharmacology of New Histamiine H1 Receptor Antagonists
1999
Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps.
1995
The place of airway hyperresponsiveness in the asthma phenotype
1995
Prednisolone Treatment in Asthma Is Associated with Modulation of Bronchoalveolar Lavage Cell Interleukin-4, Interleukin-5, and Interferon-γ Cytokine Gene Expression
1993
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The comparative actions and adverse effect profile of single doses of H1-receptor antihistamines in the airways and skin of subjects with asthma
1993
Tolerance to the Nonbronchodilator Effects of Inhaled β2-Agonists in Asthma
1992
A methodological assessment of diurnal variability of peak flow as a basis for comparing different inhaled steroid formulations
1996
Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways
2003
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2008
Effects of antihistamines in adult asthma: a meta-analysis of clinical trials
1997
Effect of Inhaled Formoterol and Budesonide on Exacerbations of Asthma
1997 Standout
Immunohistochemical Characterization of Cellular Infiltrate in Nasal Polyp from Aspirin-Sensitive Asthmatic Patients
1998
The VCAM-1 Gene That Encodes the Vascular Cell Adhesion Molecule Is a Target of the Sry-related High Mobility Group Box Gene, Sox18
2004
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Development and validation of a questionnaire to measure asthma control
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Effect of cetirizine on bronchial hyperresponsiveness in patients with seasonal allergic rhinitis and asthma
2001
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The Pharmacology and Use of H1-Receptor-Antagonist Drugs
1994
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A controlled trial of two forms of self-management education for adults with asthma
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Repair mechanisms in asthma
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Eosinophils, mast cells, and basophils in induced sputum from patients with seasonal allergic rhinitis and perennial asthma: Relationship to methacholine responsiveness☆☆☆★
1997
Adverse Effects of benzalkonium chloride on the nasal mucosa: Allergic rhinitis and rhinitis medicamentosa
1999
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2001 Standout
Highlights in cardiovascular effects of histamine and HI‐receptor ansgonists
1997
Tryptase levels in nasal-lavage fluid as an indicator of the immediate allergic response
1988
Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part I)
1994
Measurement properties and interpretation of three shortened versions of the asthma control questionnaire
2004
The development of allergic inflammation
2008 StandoutNature
Interleukin-10 inhibits antigen-induced cellular recruitment into the airways of sensitized mice.
1995
The role of adhesion molecules in human eosinophil and basophil recruitment
1994
Air pollution and health
2002 Standout
Asthma
2001 Standout
Patient Self-management of Chronic Disease in Primary Care
2002 Standout
Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial
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Eicosanoids and asthma: an update
1995
Lung inflammation and epithelial changes in a murine model of atopic asthma.
1996
Clinician’s Guide to Cardiopulmonary Exercise Testing in Adults
2010 Standout
Cetirizine
1990
Proteasome inhibition: A novel mechanism to combat asthma☆☆☆
1999
DNA antisense therapy for asthma in an animal model
1997 Nature
How much asthma is really attributable to atopy?
1999
A 12‐week, placebo‐controlled study of the efficacy and safety of ebastine, 10 and 20 mg once daily, in the treatment of perennial allergic rhinitis
1999
Leprosy
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Eosinophilic airway inflammation in nasal polyposis
1999
Improving Primary Care for Patients With Chronic Illness
2002 Standout
A comparison of cytokine release from epithelial cells cultured from nasal biopsy specimens of atopic patients with and without rhinitis and nonatopic subjects without rhinitis
1997
Astemizole
1993
Indirect airway challenges
2003
Time course of changes in adenosine 5′-monophosphate airway responsiveness with inhaled heparin in allergic asthma
1997
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial
2012 Standout
Improving Primary Care for Patients With Chronic Illness
2002 Standout
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Relationships between rhinitis and asthma
1998
Astemizole: A Long-Acting, Nonsedating Antihistamine
1987
Exercise‐induced asthma and the use of hypertonic saline aerosol as a ronchial challenge
1996
Outdoor air pollution and asthma
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Biochemistry and physiology of the leukotrienes
1999
Comparison of the efficacy of subcutaneous and sublingual immunotherapy in mite-sensitive patients with rhinitis and asthma—a placebo controlled study
1999
Cetirizine and astemizole therapy for chronic idiopathic urticaria: A double-blind, placebo-controlled, comparative trial
1995
Aspirin desensitization treatment of aspirin-sensitive patients with rhinosinusitis-asthma: Long-term outcomes
1996
Immunocompetent cells of the upper airway: Functions in normal and diseased mucosa
1995
Effect of astemizole on antigen‐mediated histamine release from the blood of patients with allergic rhinitis
1992
Cytokine expression in the lower airways of nonasthmatic subjects with allergic rhinitis: Influence of natural allergen exposure
2000
Interventions to Enhance Patient Adherence to Medication Prescriptions
2002 Standout
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
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Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults
1993
Allergic rhinitis and asthma: How important is the link?
1997
Allergic rhinitis: a rational choice of treatment
1989
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response
2000 Standout
Characterization of the inhibitory prostanoid receptors on human neutrophils
1993
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation
2007
Isolated Bronchi from Asthmatics Are Hyperresponsive to Adenosine, which Apparently Acts Indirectly by Liberation of Leukotrienes and Histamine
1992
Airways Remodeling Is a Distinctive Feature of Asthma and Is Related to Severity of Disease
1997
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Airway Inflammation in Mild Intermittent and in Persistent Asthma
1998
Physiologic Measures: Pulmonary Function Tests
1994
Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography
1997 Standout
Airway Inflammation in Occupational Asthma
1994
Guidelines for Methacholine and Exercise Challenge Testing—1999
2000 Standout
Occupational Asthma
2005
Ozone-induced Airway Inflammatory Changes Differ between Individuals and Are Reproducible
1999
Evidence for Linkage Between Asthma/Atopy in Childhood and Chromosome 5q31-q33 in a Japanese Population
1997
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2012 Standout
E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
2004 StandoutNobel
The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway
1997
The effect of inhaled sodium cromoglycate on cellular infiltration into the bronchial mucosa and the expression of adhesion molecules in asthmatics
1997
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations
1987
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
Allergen‐Induced Release of Sulphidopeptide Leukotrienes (SRS‐A) and LTB4 in Allergic Rhinitis
1985
Eosinophil cationic protein(ECP) and eosinophil protein X (EXP) concentrations in serum and bronchial lavage fluid in asthma. effect of prednisolone treatment.
1995
Inhibition of cytokine-primed eosinophil chemotaxis by nedocromil sodium
1993
Asthma : Mechanisms of Disease Persistence and Progression
2004
The leukotrienes: mediators of chronic inflammation in asthma
1996
Crosslinking of the receptors for immunoglobulin E depolarizes the plasma membrane of rat basophilic leukemia cells.
1983
Antihistamines in the treatment of asthma
1992
Comparative study of the effects of different glucocorticosteroids on eosinophil survival primed by cultured epithelial cell supernatants obtained from nasal mucosa and nasal polyps.
1995
Generation of leukotrienes by purified human lung mast cells.
1982
Guanine nucleotides modulate the binding affinity of the oligopeptide chemoattractant receptor on human polymorphonuclear leukocytes.
1983 StandoutNobel
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
2007 StandoutNobel
Mucosal Dendritic Cells
2007
The Asthma Epidemic
2006 Standout
Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force
1995
Self-management education and regular practitioner review for adults with asthma
2002
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.
1984 StandoutNobel
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
Chemotaxin-induced changes in cyclic adenosine monophosphate levels in human neutrophils
1980
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Virus-induced airway hyperresponsiveness in man
1993
Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis.
1983 StandoutNobel
Radioimmunoassay for leukotriene B 4
1982
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
Airway eosinophilia and expression of interleukin‐5 protein in asthma and in exacerbations of chronic bronchitis
1996
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Fast calcium transients in rat peritoneal mast cells are not sufficient to trigger exocytosis.
1986 StandoutNobel
Astemizole
1984
The impact of training informal health care providers in India: A randomized controlled trial
2016 StandoutScienceNobel
Mediation of local homeostasis and inflammation by leukotrienes and other mast cell-dependent compounds
1981 Nature
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.
1984 StandoutNobel
Platelet-derived growth factor-beta mRNA in human alveolar macrophages in vivo in asthma
1994
Position Paper: Allergen standardization and skin tests
1993
Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.
1996
Bronchial biopsies and airway inflammation
1996
HLA-DR- and CD11c-positive Dendritic Cells Penetrate beyond Well-developed Epithelial Tight Junctions in Human Nasal Mucosa of Allergic Rhinitis
2005
Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms.
1996
IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS
1999
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The impact of allergic rhinitis on quality of life and other airway diseases
1998
Linkage analysis of the 5q31–33 candidate region for asthma in 240 UK families
2001
Allergen-induced release of GM-CSF and IL-8 in vitro by nasal polyp tissue from atopic subjects prolongs eosinophil survival
1997
Expression of CD44 and integrins in bronchial mucosa of normal and mildly asthmatic subjects
1996
Immunopathology of fatal soybean dust-induced asthma
1996
Plasma and urinary histamine in allergen-induced early and late phase asthmatic responses.
1993
135 The effect of inhaled beclomethasone dipropionate (BDP) on inflammatory cells in the asthmatic airways
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Dendritic cells in normal and asthmatic airways: expression of the alpha subunit of the high affinity immunoglobulin E receptor (Fc epsilon RI -alpha).
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Inhibition of histamine release from dispersed human lung and tonsillar mast cells by nicardipine and nifedipine.
1985
Preferential generation of prostaglandin D2 by rat and human mast cells.
1981
Effects of indomethacin on cyclic nucleotide levels and histamine release from rat serosal mast cells.
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The reproducibility and effect on non‐specific airway responsiveness of inhaled prostaglandin D2 and leukotriene D4 in asthmatic subjects.
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Anaphylactic Release of Prostaglandins from Dispersed Human Lung Cells
1983
International Consensus Report on Diagnosis and Treatment of Asthma.
1992
The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2‐ and histamine‐induced bronchoconstriction in asthma, and relationship to plasma drug concentrations.
1992
The inflammatory response in asthma.
1991
The role of cytokines in the pathogenesis of allergic asthma.
1993
Mediators of inflammation in response to air pollution: a focus on ozone and nitrogen dioxide.
1996
Leucocyte-endothelial adhesion molecules and their role in bronchial asthma and allergic rhinitis
1993
Specific antagonism of adenosine‐induced bronchoconstriction in asthma by oral theophylline.
1985
Terfenadine, a potent histamine H1‐receptor antagonist in the treatment of grass pollen sensitive asthma.
1990
Mechanisms of purine-induced bronchoconstriction in asthma.
1990
The influence of cyclooxygenase inhibition on the loss of bronchoconstrictor response to repeated bradykinin challenge in asthma
1990
The contribution of histamine release to bronchoconstriction provoked by inhaled benzalkonium chloride in asthma.
1988
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination
1990
Repeated inhalation of bradykinin attenuates adenosine 5'-monophosphate (AMP) induced bronchoconstriction in asthmatic airways
1992
A double‐blind, placebo controlled study of the effect of the specific histamine H1‐receptor antagonist, terfenadine, in chronic severe asthma.
1995
Bronchial mucosal manifestations of atopy: a comparison of markers of inflammation between atopic asthmatics, atopic nonasthmatics and healthy controls
1992
Clinical evaluation of nedocromil sodium in asthma.
1986
The distribution of adhesive mechanisms in the normal bronchial epithelium
1993
Effect of regular inhaled beclomethasone on exercise and methacholine airway responses in school children with recurrent wheeze
1995
Inhibition of adenosine 5'-monophosphate- and methacholine-induced bronchoconstriction in asthma by inhaled frusemide
1990
Activation of human mast cells after immunoglobulin E-dependent and neuropeptide stimulation.
1989
Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5'-monophosphate
1989
The effect of 2 weeks treatment with cetirizine on bronchial reactivity to methacholine in asthma.
1990
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1999
Astemizole, a potent histamine H1‐receptor antagonist: effect in allergic rhinoconjunctivitis, on antigen and histamine induced skin weal responses and relationship to serum levels.
1984
The 1992 Cournand Lecture. Asthma: past, present and future
1993
Active sensitization of guinea-pig airways in vivo enhances in vivo and in vitro responsiveness
1988