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1996
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Exhaled Nitric Oxide Measurements in a Population Sample of Young Adults
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Natural and Experimental Rhinovirus Infections of the Lower Respiratory Tract
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Guidelines for Methacholine and Exercise Challenge Testing—1999
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Suggestive Evidence for Genetic Linkage Between IgE Phenotypes and Chromosome 14q Markers
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1998
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Cytokines as Mediators of Chronic Asthma
1994
“Refractory” Eosinophilic Airway Inflammation in Severe Asthma
2004
Airway Epithelial Cells, Cytokines, and Pollutants
1999
Lower Airways Inflammation during Rhinovirus Colds in Normal and in Asthmatic Subjects
1995
RANTES Induces Nasal Mucosal Inflammation Rich in Eosinophils, Basophils, and Lymphocytes In Vivo
1998
CD8 + T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease
1998
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
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1997
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2001
Revisiting the Roles of Mast Cells in Allergic Rhinitis and its Relation to Local IgE Synthesis
2000
Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents.
1992
Evidence for the Increase in Asthma Worldwide
2007
The leukotrienes: mediators of chronic inflammation in asthma
1996
Fluorine in medicinal chemistry
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Desensitization of the beta‐adrenoceptor of lymphocytes from normal subjects and patients with phaeochromocytoma: studies in vivo.
1978
Toxic Potential of Materials at the Nanolevel
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Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
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Allergen‐Induced Release of Sulphidopeptide Leukotrienes (SRS‐A) and LTB4 in Allergic Rhinitis
1985
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1995
The ABCs of Rhinoviruses, Wheezing, and Asthma
2010
Asthma : Mechanisms of Disease Persistence and Progression
2004
Allergic and nonallergic interactions between house dust mite allergens and airway mucosa
1997
Occurrence of exercise induced bronchospasm in elite runners: dependence on atopy and exposure to cold air and pollen.
1998
The Spreading of Disorder
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Comparison of levocabastine, a new selective H1‐receptor antagonist, and disodium cromoglycate, in a nasal provocation test with allergen.
1986
Potent antagonists for the human adenosine A2B receptor. Derivatives of the triazolotriazine adenosine receptor antagonist ZM241385 with high affinity
1999
The leukotrienes: mediators of chronic inflammation in asthma
1996
Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma
2004
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
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Sensory neuropeptides and the human lower airways: present state and future directions
1994
Antihistamines in the treatment of asthma
1992
Requirement for IL-13 Independently of IL-4 in Experimental Asthma
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Lack of Effect of Hot, Humid Air on Response to Nasal Challenge with Histamine
1996
Virus-induced airway hyperresponsiveness in man.
1993
Asthma genetics: waiting to exhale
1997
AN UPDATE ON THE PATHOPHYSIOLOGY OF RHINOVIRUS UPPER RESPIRATORY TRACT INFECTIONS
1999
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: Suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects
1990
Myeloperoxidase and interleukin‐8 levels in chronic sinusitis
1997
In Vitro Desensitization of Beta Adrenergic Receptors in Human Neutrophils. ATTENUATION BY CORTICOSTEROIDS
1983 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
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Exclusion of chromosome 11q and the FcεRI‐β gene as aetiological factors in allergy and asthma in a population of Dutch asthmatic families
1998
Cytokine Storm
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Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
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Efficacy and Safety of Nedocromil Sodium Ophthalmic Solution in the Treatment of Seasonal Allergic Conjunctivitis
1992
Mediators of inflammation in response to air pollution: a focus on ozone and nitrogen dioxide.
1996
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Metagenomics of the Human Body
2010
Leucocyte-endothelial adhesion molecules and their role in bronchial asthma and allergic rhinitis
1993
A double-blind evaluation of skin test suppression produced by two doses of terfenadine
1987
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Inflammation and the mechanism of action of anti‐inflammatory drugs
1987 Nobel
Terfenadine, a potent histamine H1‐receptor antagonist in the treatment of grass pollen sensitive asthma.
1990
Protective effects of inhaled ipratropium bromide on bronchoconstriction induced by adenosine and methacholine in asthma
1992
Virus-induced airway hyperresponsiveness in man
1993
Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease
2006
An update on the pathophysiology of rhinovirus upper respiratory tract infections.
1999
Atopic and Vernal Keratoconjunctivitis: A Model for Studying Atopic Disease
1999
Pathology of asthma
1992
P-450 Metabolites of Arachidonic Acid in the Control of Cardiovascular Function
2002
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination
1990
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Increased urinary excretion of LTE4 after exercise and attenuation of exercise-induced bronchospasm by montelukast, a cysteinyl leukotriene receptor antagonist
1997
Bronchial mucosal manifestations of atopy: a comparison of markers of inflammation between atopic asthmatics, atopic nonasthmatics and healthy controls
1992
Short‐term preseasonal birch pollen allergoid immunotherapy influences symptoms, specific nasal provocation and cytokine levels in nasal secretions, but not peripheral T‐cell responses, in patients with allergic rhinitis
1999
The effect of intranasal azelastine, Rhinolast®, on nasal airways obstruction and sneezing following provocation testing with histamine and allergen
1992
Astemizole
1984
Tolerogenic Dendritic Cells
2003 StandoutNobel
Effect of regular inhaled beclomethasone on exercise and methacholine airway responses in school children with recurrent wheeze
1995
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
2012
Should auld acquaintance be forgot…
2004
Nedocromil sodium eye drops are more effective than sodium cromoglycate eye drops for the long‐term management of vernal keratoconjunctivitis
1999
The 1992 Cournand Lecture. Asthma: past, present and future
1993
Airborne transmission of respiratory viruses
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Bronchial biopsies and airway inflammation
1996
Mast cell function modulating IgE-mediated allergy
1999
Effect of Treatment With Zileuton, a 5-Lipoxygenase Inhibitor, in Patients With Asthma
1996
Direct in vivo evidence for mast cell degranulation during allergen-induced reactions in man
1986
Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy
1995
Treatment of bronchial asthma with terfenadine; a randomized controlled trial.
1987
The role of leukotrienes in asthma and allergic rhinitis
1996
Oral antihistamine or nasal steroid in hay fever: a double‐blind double‐dummy comparative study of once daily oral astemizole vs twice daily nasal beclomethasone dipropionate
1986
Efficacy of an oral antihistamine, astemizole, as compared to a nasal steroid spray in hay fever
1988
Works of S.T. Holgate being referenced
Absorption and disposition kinetics of cromolyn sodium and the influence of inhalation technique.
1987
RANTES: a novel mediator of allergic inflammation?
1994
Airway Inflammation and Atopic Asthma: A Comparative Bronchoscopic Investigation
1991
The inhibitory actions of azelastine hydrochloride on the early and late bronchoconstrictor responses to inhaled allergen in atopic asthma
1989
Ozone, airways and allergic airways disease
1995
The Interaction between Immunoglobulin E and Smoking in Airflow Obstruction in the Elderly
1992
Predicting and evaluating response to omalizumab in patients with severe allergic asthma
2007
Adenosine as a pro-inflammatory mediator in asthma
1989
The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects
1997
The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics.
1997
Asthma mechanisms, determinants of severity and treatment: the role of nedocromil sodium Report of a workshop held in Whistler, British Columbia, Canada, 18–19 May 1995
1995
The protective efficacy of inhaled, oral and intravenous nedocromil sodium against adenosine-5′-monophosphate-induced bronchoconstriction in asthmatic volunteers
1990
Effect of inhaled corticosteroids on episodes of wheezing associated with viral infection in school age children: randomised double blind placebo controlled trial
1997
Epithelially Derived Endothelin and Nitric Oxide in Asthma
1995
Comparative protective effect of the inhaled β2-agonist salbutamol (albuterol) on bronchoconstriction provoked by histamine, methacholine, and adenosine 5′-monophosphate in asthma
1990
Immunohistochemical analysis of nasal biopsies during rhinovirus experimental colds.
1994
Nedocromil sodium is more potent than sodium cromoglycate against AMP‐induced bronchoconstriction in atopic asthmatic subjects
1989
Mast cell numbers and staining characteristics in the normal and allergic human conjunctiva
1991
Effect of Inhaled Platelet-Activating Factor on Bronchial Inflammation in Atopic Non-Asthmatic Subjects
1992
Sensitivity to Parietaria pollen in the Southampton area as determined by skin‐prick and RAST tests
1988
The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5′-monophosphate and histamine in asthma
1991
Genetic analysis of atopy and asthma as quantitative traits and ordered polychotomies
1994
Mucosal Cytokine Expression in Allergic Rhinitis
1995
Role of Leukotrienes in Exercise-induced Asthma: Inhibitory Effect of ICI 204219, a Potent Leukotriene D 4 Receptor Antagonist
1992
The Effect of Oral Terfenadine Alone and in Combination with Flurbiprofen on the Bronchoconstrictor Response to Inhaled Adenosine 5′-Monophosphate in Nonatopic Asthma
1989
Rhinoviruses Infect the Lower Airways
2000
The effects ofMycobacterium vaccaeon allergen-induced airway responses in atopic asthma
2003
The natural history of bronchial hyperresponsiveness
1989
Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma
1990
The effect of the orally active platelet-activating factor antagonist WEB 2086 in the treatment of asthma.
1994
Montelukast or salmeterol combined with an inhaled steroid in adult asthma: design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial)
2000
Inhibition of Hypertonic Saline-induced Bronchoconstriction by Terfenadine and Flurbiprofen: Evidence for the Predominant Role of Histamine
1989
Mucosal Nerves in Endobronchial Biopsies in Asthma and Non-Asthma
1991
Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus-induced asthma.
1997
Effect of Nedocromil Sodium on Early and Late Phase Responses to Allergen Challenge in the Guinea-Pig
1989
Duration of growth suppressive effects of regular inhaled corticosteroids
1998
Influence of interleukin-8 challenge in the nasal mucosa in atopic and nonatopic subjects.
1994
The Protective Effect of Inhaled Leukotriene D 4 Receptor Antagonist ICI 204,219 against Exercise-induced Asthma
1993
Laser Doppler flowmetry for determining changes in cutaneous blood flow following intradermal injection of histamine
1987
Adenosine: a Positive Modulator of Airway Inflammation in Asthma
1991
Cellular infiltration of the airways in asthma of varying severity.
1996
Early and Late-Phase Bronchoconstriction After Allergen Challenge of Nonanesthetized Guinea Pigs: I. The Association of Disordered Airway Physiology to Leukocyte Infiltration
1988
The Inhibitory Effect of Nebulized Albuterol on the Early and Late Asthmatic Reactions and Increase in Airway Responsiveness Provoked by Inhaled Allergen in Asthma
1991
New Insights into Airway Inflammation by Endobronchial Biopsy
1992
The role of a soluble TNF receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial
2008
Adenosine A2B receptors: a novel therapeutic target in asthma?
1998
Comparative Airway Response to Inhaled Bradykinin, Kallidin, and [des-Arg 9 ]Bradykinin in Normal and Asthmatic Subjects
1990
The temporal relationship between the neural and vascular actions of kallidin within the nose
1993
The in vivo potency and selectivity of azelastine as an H1 histamine-receptor antagonist in human airways and skin
1988
Circulating adhesion molecules in asthma.
1994
Evidence That Neutrophils Do Not Participate in the Late-Phase Airway Response Provoked by Ovalbumin Inhalation in Conscious, Sensitized Guinea Pigs
1990
The Response of Plasma Histamine to Bronchoprovocation with Methacholine, Adenosine 5′-monophosphate, and Allergen in Atopic Nonasthmatic Subjects
1990
Leukocyte recruitment after local endobronchial allergen challenge in asthma. Relationship to procedure and to airway interleukin-8 release.
1996
The effects of theophylline on mucosal inflammation in asthmatic airways: biopsy results
1995
The effect of inhaled 15-(s)-hydroxyeicosatetraenoic acid (15-HETE) on airway calibre and non-specific responsiveness in normal and asthmatic human subjects
1990
Bronchial reactivity to histamine and bradykinin is unchanged after rhinovirus infection in normal subjects
1992
A longitudinal study of baseline FEV1 and bronchial responsiveness in patients with asthma
1992
Prevalence of atopy and range of bronchial response to methacholine in 7 and 11 year old schoolchildren.
1989
263 Neutrophils do not participate in the development of the late asthmatic reaction (LAR) in guinea-pigs
1988
Interaction of inhaled LTC4 with histamine and PGD2 on airway caliber in asthma
1989
Does non-specific bronchial responsiveness indicate the severity of asthma?
1990
Compromised concentrations of ascorbate in fluid lining the respiratory tract in human subjects after exposure to ozone.
1999
INTRAVENOUS PREDNISOLONE IN ASTHMA
1976
Effect of GR32191, a potent thromboxane receptor antagonist, on exercise induced bronchoconstriction in asthma.
1991
The effect of histamine‐H1 receptor antagonism with terfenadine on concentration‐related AMP‐induced bronchoconstriction in asthma
1989
Airway response to exercise and methacholine in children with respiratory symptoms.
1991
Comparison of the efficacy of preservative free ipratropium bromide and Atrovent nebuliser solution.
1988
The epidemic of asthma and allergy
2004
Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma.
1999
Allergic disorders
2000
Effect of methacholine induced bronchoconstriction on the pulmonary distribution and plasma pharmacokinetics of inhaled sodium cromoglycate in subjects with normal and hyperreactive airways.
1988
Attenuation of exercise induced asthma by local hyperthermia.
1992
Comparative trial of two non-sedative H1 antihistamines, terfenadine and astemizole, for hay fever.
1984
New perspectives on the putative role of eicosanoids in airway hyperresponsiveness
1985
Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways.
1987
Tumour necrosis factor alpha: a polcnlial mediator of asthma
1995
Bronchoconstrictor and antibronchoconstrictor properties of inhaled prostacyclin in asthma
1988
Nitric oxide synthase in asthmatic human lung
1993
Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction
1989
144 Airway hyperreactivity and mediator release in clinical models of asthma
1985
Reduced Selenium Status of Patients with Asthma
1989
Inhaled PAF fails to induce airway hyperresponsiveness to methacholine in normal human subjects
1990
Symptoms, atopy, and bronchial response to methacholine in parents with asthma and their children.
1987
Airway and cardiovascular responses to inhaled prostacyclin in normal and asthmatic subjects.
1985
Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms.
1996
285 Bronchial mucosal intercellular adhesion molecule-1 [ICAM-1] and endothelial leukocyte adhesion molecule-1 [ELAM-1] expression in normals and asthmatics
1991
Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma
1986