Standout Papers
Citation Impact
Citing Papers
Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells
2011
Regulation of Flowering Time by Histone Acetylation in Arabidopsis
2003 Science
Positional cloning of the wheat vernalization gene VRN1
2003 Standout
Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes
2011
Regulatory T-cells in autoimmune diseases: Challenges, controversies and—yet—unanswered questions
2014
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1
2004 Standout
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Regulatory T-cell directed therapies in liver diseases
2013 StandoutNobel
Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity
2017
Differential Effects of IL-12 on Tregs and Non-Treg T Cells: Roles of IFN-γ, IL-2 and IL-2R
2012
Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency
2018
Myocardial viability as a determinant of the ejection fraction response to carvedilol in patients with heart failure (CHRISTMAS trial): randomised controlled trial
2003
Molecular Mechanisms Controlling Foxp3 Expression in Health and Autoimmunity: From Epigenetic to Post-translational Regulation
2020
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127low regulatory T cells
2012
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
2015 Standout
Molecular Bases for Circadian Clocks
1999 Standout
Protein tyrosine phosphatases in lymphocyte activation and autoimmunity
2012
Rheumatoid arthritis
2016 Standout
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention
2011 Standout
The inflammatory milieu in the rheumatic joint reduces regulatory T‐cell function
2011
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure
2005
The Failing Heart — An Engine Out of Fuel
2007 Standout
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
2008
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
2006 Standout
Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)
2014
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases
2013
Etiology of Type 1 Diabetes
2010
The changing landscape of atherosclerosis
2021 StandoutNature
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Historical Overview of Immunological Tolerance
2012
The Effect of Cardiac Resynchronization on Morbidity and Mortality in Heart Failure
2005 Standout
Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis
2009
Genetics, pathogenesis and clinical interventions in type 1 diabetes
2010 Nature
Inducing and Administering Tregs to Treat Human Disease
2016
Phytochromes and light signal perception by plants—an emerging synthesis
2000 StandoutNature
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes
2016 StandoutNobel
Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases
2021
Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response
2013
Regulatory T cells in autoimmune disease
2018
A plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes
2014
Impaired suppression of synovial fluid CD4+CD25− T cells from patients with juvenile idiopathic arthritis by CD4+CD25+ Treg cells
2011
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
FOXP3 and scurfy: how it all began
2014 StandoutNobel
The regulation of immune tolerance by FOXP3
2017
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism
2018
Foxp3: a genetic foundation for regulatory T cell differentiation and function
2020 StandoutNobel
Regulatory T cell proliferative potential is impaired in human autoimmune disease
2013
Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor
2016
Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease
2016
The PD‐1 pathway in tolerance and autoimmunity
2010 Standout
Antagonistic regulation of flowering-time gene SOC1 by CONSTANS and FLC via separate promoter motifs
2002
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Type 1 diabetes
2013 Standout
Targeting Treg signaling for the treatment of autoimmune diseases
2015
Heart failure
2005
The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes
2021
Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity
2013
Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention
2007 Standout
TREG-cell therapies for autoimmune rheumatic diseases
2014 StandoutNobel
The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis
2016 StandoutNobel
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models
2013
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
2020 StandoutNobel
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Opportunities for Treg cell therapy for the treatment of human disease
2023 StandoutNobel
Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity
2010
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
2013
Treg cell-based therapies: challenges and perspectives
2019
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
New Roles for β-Arrestins in Cell Signaling: Not Just for Seven-Transmembrane Receptors
2006 StandoutNobel
Clinical trials update and cumulative meta‐analyses from the American College of Cardiology: WATCH, SCD‐HeFT, DINAMIT, CASINO, INSPIRE, STRATUS‐US, RIO‐Lipids and cardiac resynchronisation therapy in heart failure
2004
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Clinical application of regulatory T cells in type 1 diabetes
2013
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
Citrulline‐Specific Th1 Cells Are Increased in Rheumatoid Arthritis and Their Frequency Is Influenced by Disease Duration and Therapy
2014
FLOWERING LOCUS C Encodes a Novel MADS Domain Protein That Acts as a Repressor of Flowering
1999 Standout
Regulatory T Cells and Human Disease
2020 StandoutNobel
Tyrosine Phosphatase PTPN22: Multifunctional Regulator of Immune Signaling, Development, and Disease
2013
B7x in the Periphery Abrogates Pancreas-Specific Damage Mediated by Self-reactive CD8 T Cells
2012 StandoutNobel
Analysis of Natural Allelic Variation at Flowering Time Loci in the Landsberg erecta and Cape Verde Islands Ecotypes of Arabidopsis thaliana
1998
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation
2019 StandoutNobel
Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis
2020
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
2016 StandoutNobel
Myocardial Viability Testing and the Effect of Early Intervention in Patients With Advanced Left Ventricular Systolic Dysfunction
2006
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2
2013
Benefit and risk in tissue engineering
2004
Chimeric Antigen Receptor Therapy
2018 Standout
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
2015 Standout
Molecular Analysis of FRIGIDA , a Major Determinant of Natural Variation in Arabidopsis Flowering Time
2000 Science
Immunotherapy: Building a bridge to a cure for type 1 diabetes
2021 Science
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
CD4+CD45RA−FoxP3high activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes
2013
PTPN22 Controls the Germinal Center by Influencing the Numbers and Activity of T Follicular Helper Cells
2014
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game
2011
Effects of interleukin-2 in immunostimulation and immunosuppression
2019
IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells
2013
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
2015
Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling
2015
PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes–Associated Allele Is Not a Loss-of-Function Variant
2012
Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice
2017 StandoutNobel
The short-period mutant, toc1-1, alters circadian clock regulation of multiple outputs throughout development in Arabidopsis thaliana
1998
Works of Srinath Sanda being referenced
Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs β-Cell Function
2012
Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects
2009
Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin
2010
Functional islet‐specific Treg can be generated from CD4+CD25− T cells of healthy and type 1 diabetic subjects
2009
Analysis of Flowering Time in Ecotypes of Arabidopsis thaliana
1997
Interaction ofFLC and late-flowering mutations inArabidopsis thaliana
1996
Type 1 diabetes as a relapsing–remitting disease?
2007
Islet antigen specific IL-10+ immune responses but not CD4+CD25+FoxP3+ cells at diagnosis predict glycemic control in type 1 diabetes
2008
The heart failure revascularisation trial (HEART): rationale, design and methodology
2003
The Effector T Cells of Diabetic Subjects Are Resistant to Regulation via CD4+FOXP3+ Regulatory T Cells
2008
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1
2012
Ecotype-Specific Expression of a Flowering Mutant Phenotype in Arabidopsis thaliana
1996
Evaluation of in vivo T cell kinetics: use of heavy isotope labelling in type 1 diabetes
2013
Altered B Cell Homeostasis Is Associated with Type I Diabetes and Carriers of the PTPN22 Allelic Variant
2011
2012
Through the Fog: Recent Clinical Trials to Preserve β-Cell Function in Type 1 Diabetes
2012