Citation Impact

Citing Papers

2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
2018
Kinetics of FKBP12.6 Binding to Ryanodine Receptors in Permeabilized Cardiac Myocytes and Effects on Ca Sparks
2010
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary
2014 Standout
Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell
2018
Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface
2013
Sensing intracellular calcium ions using a manganese-based MRI contrast agent
2019
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Redox Sensitivity of the Ryanodine Receptor Interaction with FK506-binding Protein
2007
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
Ryanodine receptors and ventricular arrhythmias: Emerging trends in mutations, mechanisms and therapies
2006
Skeletal Muscle Fatigue: Cellular Mechanisms
2008 Standout
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Ryanodine Receptors: Allosteric Ion Channel Giants
2014
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
EXCITATION–CONTRACTION COUPLING FROM THE 1950s INTO THE NEW MILLENNIUM
2006
Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein
2017 NatureNobel
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Pericytes of the neurovascular unit: key functions and signaling pathways
2016
Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain
2012
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Structure of frozen–hydrated triad junctions: A case study in motif searching inside tomograms
2008 StandoutNobel
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
Caffeine induced Ca2+ release and capacitative Ca2+ entry in human embryonic kidney (HEK293) cells
2005
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment
2017 StandoutNobel
Exercise Standards for Testing and Training
2013 Standout
High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers
2019
Cell Biology of Ischemia/Reperfusion Injury
2012 Standout
Ryanodine receptor channelopathies
2004
Architecture and conformational switch mechanism of the ryanodine receptor
2014 Nature
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
2018 Standout
Superresolution microscopy in heart — Cardiac nanoscopy
2012 StandoutNobel
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
Calcium Sparks
2008
Outcomes of defibrillator therapy in catecholaminergic polymorphic ventricular tachycardia
2013
Regulation of blood flow in the microcirculation: role of conducted vasodilation
2010
Na/K-ATPase—An Integral Player in the Adrenergic Fight-or-Flight Response
2009
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
2012
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Pyroptosis: mechanisms and diseases
2021 Standout
Recent advances in the molecular pathophysiology of atrial fibrillation
2011
Macromolecular complexes regulating cardiac ryanodine receptor function
2004
Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033
2010 StandoutNobel
The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule
2010 Nature
A tyrosine residue in TM6 of the Vanilloid Receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents
2003
Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons*
2010 StandoutNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Modulation of P2X4/P2X7/Pannexin-1 sensitivity to extracellular ATP via Ivermectin induces a non-apoptotic and inflammatory form of cancer cell death
2015
The Pore Structure of the Closed RyR1 Channel
2005
Ca2+ sparks as a plastic signal for skeletal muscle health, aging, and dystrophy
2006
Dantrolene Inhibition of Ryanodine Receptor Ca2+Release Channels
2001
Nanoscale organization of nicotinic acetylcholine receptors revealed by stimulated emission depletion microscopy
2006 StandoutNobel
Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling
2017
Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle
2004
Pyroptosis: A new frontier in cancer
2019 Standout
FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death
2003
Functional Characterization of the Cardiac Ryanodine Receptor Pore-Forming Region
2013
Catecholaminergic Polymorphic Ventricular Tachycardia
2008
Membrane mimetic systems in CryoEM: keeping membrane proteins in their native environment
2019 StandoutNobel
Supramolecular Assemblies and Localized Regulation of Voltage-Gated Ion Channels
2009
Calcium Signaling
2007 Standout
The Pathobiology of Vascular Dementia
2013 Standout
Transient Receptor Potential Cation Channels in Disease
2007 Standout
Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant
2015
Calcium Green FlAsH as a genetically targeted small-molecule calcium indicator
2007 StandoutNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain
2014
Modulation of the Ryanodine Receptor and Intracellular Calcium
2007
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Defective Cardiac Ryanodine Receptor Regulation During Atrial Fibrillation
2005
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Ca 2+ /Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor
2004
Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure
2005
Abnormal Calcium Signaling and Sudden Cardiac Death Associated With Mutation of Calsequestrin
2004
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Management of Acute Myocarditis and Chronic Inflammatory Cardiomyopathy
2020 Standout
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
2015 Standout
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
Single-nanometer iron oxide nanoparticles as tissue-permeable MRI contrast agents
2021 StandoutNobel
“Optical Patch-clamping”
2005
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Ion channel networks in the control of cerebral blood flow
2015
INTRACELLULAR CALCIUM RELEASE AND CARDIAC DISEASE
2004
Determination of the ribosome structure to a resolution of 2.5 Å by single‐particle cryo‐EM
2016 StandoutNobel
2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
2017

Works of S.R. Wayne Chen being referenced

Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2
2016 Science
Reduced Threshold for Luminal Ca2+ Activation of RyR1 Underlies a Causal Mechanism of Porcine Malignant Hyperthermia
2008
Removal of FKBP12.6 Does Not Alter the Conductance and Activation of the Cardiac Ryanodine Receptor or the Susceptibility to Stress-induced Ventricular Arrhythmias
2007
The EF-hand Ca2+ Binding Domain Is Not Required for Cytosolic Ca2+ Activation of the Cardiac Ryanodine Receptor
2015
Intravascular pressure augments cerebral arterial constriction by inducing voltage-insensitive Ca2+waves
2010
Localization of the Dantrolene-binding Sequence near the FK506-binding Protein-binding Site in the Three-dimensional Structure of the Ryanodine Receptor
2011
Diffusion of Single Cardiac Ryanodine Receptors in Lipid Bilayers Is Decreased by Annexin 12
2004
Ligand-dependent Conformational Changes in the Clamp Region of the Cardiac Ryanodine Receptor
2012
Changes in Negative Charge at the Luminal Mouth of the Pore Alter Ion Handling and Gating in the Cardiac Ryanodine-Receptor
2009
Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes
2000
Conformational Dynamics inside Amino-Terminal Disease Hotspot of Ryanodine Receptor
2013
Location of Divergent Region 2 on the Three-dimensional Structure of Cardiac Muscle Ryanodine Receptor/Calcium Release Channel
2004
Role of CaMKII and ROS in rapid pacing-induced apoptosis
2013
Store overload‐induced Ca2+ release as a triggering mechanism for CPVT and MH episodes caused by mutations in RYR and CASQ genes
2009
Enhanced Basal Activity of a Cardiac Ca 2+ Release Channel (Ryanodine Receptor) Mutant Associated With Ventricular Tachycardia and Sudden Death
2002
Two potential calmodulin-binding sequences in the ryanodine receptor contribute to a mobile, intra-subunit calmodulin-binding domain
2013
Abnormal Termination of Ca 2+ Release Is a Common Defect of RyR2 Mutations Associated With Cardiomyopathies
2012
Inherited Dysfunction of Sarcoplasmic Reticulum Ca 2+ Handling and Arrhythmogenesis
2011
Protein Kinase A Phosphorylation at Serine-2808 of the Cardiac Ca 2+ -Release Channel (Ryanodine Receptor) Does Not Dissociate 12.6-kDa FK506-Binding Protein (FKBP12.6)
2004
HEK-293 cells possess a carbachol- and thapsigargin-sensitive intracellular Ca2+ store that is responsive to stop-flow medium changes and insensitive to caffeine and ryanodine
1999
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2026