Citation Impact
Citing Papers
Molecular Chaperone Functions in Protein Folding and Proteostasis
2013
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma
2017
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
2009 Standout
Rheb localized on the Golgi membrane activates lysosome-localized mTORC1 at the Golgi–lysosome contact site
2017
Activity-independent targeting of mTOR to lysosomes in primary osteoclasts
2017
Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
2009 Standout
Autophagosome Precursor Maturation Requires Homotypic Fusion
2011
HIV-1 Inhibits Autophagy in Bystander Macrophage/Monocytic Cells through Src-Akt and STAT3
2010
Hallmarks of Cancer: The Next Generation
2011 Standout
Autophagy in cancers including brain tumors: role of MicroRNAs
2020
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
ER–lysosome contacts enable cholesterol sensing by mTORC1 and drive aberrant growth signalling in Niemann–Pick type C
2019
Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk
2016
Induction of macroautophagy by exogenously introduced calcium
2008
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
The role of the Atg1/ULK1 complex in autophagy regulation
2010 Standout
The Role of Autophagy in Parkinson's Disease
2012
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Autophagy in infection, inflammation and immunity
2013 Standout
mTOR Signaling in Growth Control and Disease
2012 Standout
Autophagy and Viruses: Adversaries or Allies?
2013 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant
2008
Clarifying lysosomal storage diseases
2011
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
2014
Cargo recognition and degradation by selective autophagy
2018
Autophagy and the Integrated Stress Response
2010 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
2017
Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
2014
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
2010
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
2009
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
2009
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Vesicular trafficking and autophagosome formation
2009
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β
2011
Autophagy in the Cellular Energetic Balance
2011
Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders
2017
Amino acids and mTORC1: from lysosomes to disease
2012
The Salmonella Deubiquitinase SseL Inhibits Selective Autophagy of Cytosolic Aggregates
2012
Role of autophagy in cancer
2007 Standout
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
2010
The cellular pathology of lysosomal diseases
2011
TOR-dependent control of autophagy: biting the hand that feeds
2009
Can autophagy promote longevity?
2010
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
2017
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
2011
DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
2017
Plasma membrane contributes to the formation of pre-autophagosomal structures
2010
Autophagy in lysosomal storage disorders
2012
FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
2007
Chemical modulators of autophagy as biological probes and potential therapeutics
2010
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
2013
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos
2009
FoxO3 Controls Autophagy in Skeletal Muscle In Vivo
2007 Standout
Autophagy gone awry in neurodegenerative diseases
2010
Autophagy in the Pathogenesis of Disease
2008 Standout
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
2010
Mechanisms of Age-Related Macular Degeneration
2012
Potential therapeutic applications of autophagy
2007
The roles of intracellular protein-degradation pathways in neurodegeneration
2006 Nature
Repeat expansion disease: progress and puzzles in disease pathogenesis
2010
Cell Death
2009
Autophagy in Human Health and Disease
2013 Standout
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
2010
Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney
2018
The Beclin 1 network regulates autophagy and apoptosis
2011 Standout
Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy
2016
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
2013
Methods in Mammalian Autophagy Research
2010 Standout
Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
2014
The propagation of prion-like protein inclusions in neurodegenerative diseases
2010
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
mTOR Regulates Lysosomal ATP-Sensitive Two-Pore Na+ Channels to Adapt to Metabolic State
2013
Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1
2007
Regulation of autophagy by ATF4 in response to severe hypoxia
2010
Autophagy and Aging
2011 Standout
Lipophagy and liver disease: New perspectives to better understanding and therapy
2017
Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism
2015
Basic mechanisms of neurodegeneration: a critical update
2010
Hepatocyte growth factor has a role in the amelioration of diabetic vascular complications via autophagic clearance of advanced glycation end products: Dispo85E, an HGF inducer, as a potential botanical drug
2010
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies
2007
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
2012
Control of autophagy as a therapy for neurodegenerative disease
2011
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
2012
Autophagy: process and function
2007 Standout
The Hallmarks of Aging
2013 Standout
Trehalose transporter from African chironomid larvae improves desiccation tolerance of Chinese hamster ovary cells
2011
Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy
2013
Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
2010
Molecular logic of mTORC1 signalling as a metabolic rheostat
2019
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Listeria monocytogenes ActA-mediated escape from autophagic recognition
2009
Autophagy and human diseases
2013
Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model
2016
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
2009
Rapamycin Inhibits Polyglutamine Aggregation Independently of Autophagy by Reducing Protein Synthesis
2008
Pathogenic Lysosomal Depletion in Parkinson's Disease
2010
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase
2017 StandoutNobel
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis
2019
TBC1D20 mediates autophagy as a key regulator of autophagosome maturation
2016
AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets
2011
Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein.
2003
Inflammaging: disturbed interplay between autophagy and inflammasomes
2012
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
mTOR's role in ageing: protein synthesis or autophagy?
2009
Autophagy is an adaptive response in desmin-related cardiomyopathy
2008
Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy
2012
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging
2011 Science
Beclin-1-Dependent Autophagy Protects the Heart During Sepsis
2018
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
2012
Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae
2015 StandoutNobel
Measurement of Autophagy in Cells and Tissues
2010
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Huntington's disease: from pathology and genetics to potential therapies
2008
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
2008
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
2008 Standout
Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
2009
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
2000 Standout
Regulation of TFEB and V-ATPases by mTORC1
2011
Canonical and non-canonical autophagy: variations on a common theme of self-eating?
2011
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Rotational dynamics and transition mechanisms of surface-adsorbed proteins
2022 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Autophagy in stem cells: repair, remodelling and metabolic reprogramming
2018
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding
2018
Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing
2017
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
2015 StandoutNobel
Small molecule regulators of autophagy identified by an image-based high-throughput screen
2007
Mechanisms of Diabetic Complications
2013 Standout
Macroautophagy Regulates Energy Metabolism during Effector T Cell Activation
2010
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
2010
IP3Receptors, Mitochondria, and Ca2+Signaling: Implications for Aging
2011
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
TOR and RAS pathways regulate desiccation tolerance inSaccharomyces cerevisiae
2012
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
The Double-Edged Sword of Autophagy Modulation in Cancer
2009
The position of lysosomes within the cell determines their luminal pH
2016
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Rapid Hypothesis Testing with Candida albicans through Gene Disruption with Short Homology Regions
1999
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020
Works of Sovan Sarkar being referenced
Small molecule enhancers of autophagy for neurodegenerative diseases
2008
The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias
2007
Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis
2014
Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells
2014
Trehalose reduces aggregate formation and delays pathology in a transgenic mouse model of oculopharyngeal muscular dystrophy
2005
SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability
2014
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
2010
Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein
2006
Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation
2015
Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease
2013
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
2007
Huntington’s disease: degradation of mutant huntingtin by autophagy
2008
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease
2010
Inositol and IP3 Levels Regulate Autophagy—Biology and Therapeutic Speculations
2005
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
2007
Chapter 5 Autophagic Clearance of Aggregate‐Prone Proteins Associated with Neurodegeneration
2009
Restarting stalled autophagy a potential therapeutic approach for the lipid storage disorder, Niemann-Pick type C1 disease
2014
Lysosomal positioning coordinates cellular nutrient responses
2011
Complex Inhibitory Effects of Nitric Oxide on Autophagy
2011
Autophagy, lipophagy and lysosomal lipid storage disorders
2016
Aggregate‐Prone Proteins Are Cleared from the Cytosol by Autophagy: Therapeutic Implications
2006
Clearance of Mutant Aggregate-Prone Proteins by Autophagy
2008
Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases
2010
Methodological considerations for assessing autophagy modulators: A study with calcium phosphate precipitates
2009
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
2008
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
2008
Deletion of the Huntingtin Polyglutamine Stretch Enhances Neuronal Autophagy and Longevity in Mice
2010
DNA Interstrand Cross-Link Repair in the Cell Cycle: A Critical Role for Polymerase ζ in G1 Phase
2006
Lithium induces autophagy by inhibiting inositol monophosphatase
2005
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics
2015
Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety.
1995
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
2016
Dysregulation of autophagy as a common mechanism in lysosomal storage diseases
2017
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
2013
The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid- and alkaline-expressed genes by ambient pH.
1995
Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
2008
Mammalian macroautophagy at a glance
2009
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function
2007