Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
A Small-Molecule Modulator of Poly-α2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells
2001 StandoutScienceNobel
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation
2003 StandoutNobel
Photocrosslinkers illuminate interactions in living cells
2008
Metabolic oligosaccharide engineering: perspectives, applications, and future directions
2007
The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid–binding lectin SIGLEC7 on the cell surface
2019
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
2019 StandoutNobel
Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
2006
Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins
2018
Achievements and challenges of sialic acid research
2000
Exploring the glycan repertoire of genetically modified mice by isolation and profiling of the major glycan classes and nano-NMR analysis of glycan mixtures
2000
Siglec-mediated regulation of immune cell function in disease
2014
Siglec functions of microglia
2014
Biosynthetic Modulation of Sialic Acid-dependent Virus-Receptor Interactions of Two Primate Polyoma Viruses
1995
Purification and cDNA Cloning of a Human UDP-N-acetyl-α- D-galactosamine:polypeptide N-Acetylgalactosaminyltransferase
1995
Siglecs and their roles in the immune system
2007 Standout
Glycosylation: Heterogeneity and the 3D Structure of Proteins
1997
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Chemical Technologies for Probing Glycans
2006 StandoutNobel
Tumor-Associated Macrophages in Breast Cancer
2002
Syntheses and some applications of chemically defined multivalent glycoconjugates
1996
Genetic Compatibility and Virulence of Reassortants Derived from Contemporary Avian H5N1 and Human H3N2 Influenza A Viruses
2008
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Binding of the Influenza A Virus to Cell-Surface Receptors: Structures of Five Hemagglutinin–Sialyloligosaccharide Complexes Determined by X-Ray Crystallography
1997
Associations of genetic polymorphisms of Siglecs with human diseases
2014
Synthetic multivalent ligands in the exploration of cell-surface interactions
2000
Methyl α‐glycoside of N‐thioacetyl‐d ‐neuraminic acid: A potential inhibitor of influenza A virus a 1H NMR study
1993
Differential and Cooperative Polysialylation of the Neural Cell Adhesion Molecule by Two Polysialyltransferases, PST and STX
1998
Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking
2005
Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor
1994
Sialic Acid Capping of CD8β Core 1-O-Glycans Controls Thymocyte-Major Histocompatibility Complex Class I Interaction
2003
New sialic acids from biological sources identified by a comprehensive and sensitive approach: liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) of SIA quinoxalinones
1997
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Expression of CD33-related siglecs on human mononuclear phagocytes, monocyte-derived dendritic cells and plasmacytoid dendritic cells
2004
Metabolic oligosaccharide engineering as a tool for glycobiology
2003
Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions
2012
Molecular basis of human CD22 function and therapeutic targeting
2017
Highly Efficient Chemoenzymatic Synthesis of Naturally Occurring and Non‐Natural α‐2,6‐Linked Sialosides: A P. damsela α‐2,6‐Sialyltransferase with Extremely Flexible Donor–Substrate Specificity
2006
Biology of Animal Lectins
1993
Siglecs at the Host–Pathogen Interface
2020
High Resolution Crystal Structures of Siglec-7
2003
Lectins: Carbohydrate-specific Reagents and Biological Recognition Molecules
2006
CD22 is a negative regulator of B-cell receptor signalling
1997 Nobel
Cloning, Characterization, and Phylogenetic Analysis of Siglec-9, a New Member of the CD33-related Group of Siglecs
2000
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Cell surface biology mediated by low affinity multivalent protein–glycan interactions
2004
Photocrosslinking of glycoconjugates using metabolically incorporated diazirine-containing sugars
2009
Potent Glycan Inhibitors of Myelin-associated Glycoprotein Enhance Axon Outgrowth in Vitro
2005
Studies of the Binding Properties of Influenza Hemagglutinin Receptor-Site Mutants
1998
Concepts and Principles of O-Linked Glycosylation
1998
Sialic acid-specific lectins: occurrence, specificity and function
2006
Chemical remodelling of cell surfaces in living animals
2004 StandoutNatureNobel
Loss of N-Glycolylneuraminic Acid in Human Evolution
2000
Membrane Fusion
2003 StandoutNobel
Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and x-ray crystallography
1992
In vivo modulated N‐acyl side chain of N‐acetylneuraminic acid modulates the cell contact‐dependent inhibition of growth
1996
Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches
2015
Proton nuclear magnetic resonance studies of the binding of sialosides to intact influenza virus
1992
Crystal structures of murine polyomavirus in complex with straight-chain and branched-chain sialyloligosaccharide receptor fragments
1996
CD22 as a target of passive immunotherapy
2003
X-ray Crystal Structure of the Soybean Agglutinin Cross-Linked with a Biantennary Analog of the Blood Group I Carbohydrate Antigen
1995
Role of Hemagglutinin Cleavage for the Pathogenicity of Influenza Virus
1999
Negative Regulation of Toll-like Receptor-4 Signaling through the Binding of Glycosylphosphatidylinositol-anchored Glycoprotein, CD14, with the Sialic Acid-binding Lectin, CD33
2014
Atherosclerosis — An Inflammatory Disease
1999 Standout
Selectins and other mammalian sialic acid-binding lectins
1992
The ST3Gal-I Sialyltransferase Controls CD8+ T Lymphocyte Homeostasis by Modulating O-Glycan Biosynthesis
2000
Genetic analysis of two influenza A (H1) swine viruses isolated from humans in Thailand and the Philippines
2007
Click and Pick: Identification of Sialoside Analogues for Siglec‐Based Cell Targeting
2012
Universal primer set for the full-length amplification of all influenza A viruses
2001 Standout
Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligands
2015
Conversion of cellular sialic acid expression from N-acetyl- to N-glycolylneuraminic acid using a synthetic precursor, N-glycolylmannosamine pentaacetate: inhibition of myelin-associated glycoprotein binding to neural cells
2000
Siglec-9, a Novel Sialic Acid Binding Member of the Immunoglobulin Superfamily Expressed Broadly on Human Blood Leukocytes
2000
Negative Regulation of T Cell Receptor Signaling by Siglec-7 (p70/AIRM) and Siglec-9
2004
TNF/iNOS-Producing Dendritic Cells Mediate Innate Immune Defense against Bacterial Infection
2003
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
A structural difference between the cell surfaces of humans and the great apes
1998
lec32 Is a New Mutation in Chinese Hamster Ovary Cells That Essentially Abrogates CMP-N-acetylneuraminic Acid Synthetase Activity
1995
Elongation of theN-Acyl Side Chain of Sialic Acids in MDCK II Cells Inhibits Influenza A Virus Infection
1998
Strength in numbers: non-natural polyvalent carbohydrate derivatives
1996
Glycan Array Screening Reveals a Candidate Ligand for Siglec-8*
2004
Emergence and pandemic potential of swine-origin H1N1 influenza virus
2009 Nature
Molecular Cloning of Cytidine Monophospho-N-acetylneuraminic Acid Hydroxylase. REGULATION OF SPECIES- AND TISSUE-SPECIFIC EXPRESSION OF N-GLYCOLYLNEURAMINIC ACID
1995
Carbohydrate recognition systems: functional triads in cell—cell interactions
1996
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Multifarious roles of sialic acids in immunity
2012
Siglec-7: a sialic acid-binding lectin of the immunoglobulin superfamily
2000
The molecular and cell biology of glycosyltransferases
1993
Azido Sialic Acids Can Modulate Cell‐Surface Interactions
2004 StandoutNobel
Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis
2016
The Human Condition—A Molecular Approach
2014 StandoutNobel
The Molecular Basis for the Absence ofN-Glycolylneuraminic Acid in Humans
1998
Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec‐7‐dependent and ‐independent mechanisms
2003
[11] Sialic acid analogs and application for preparation of neoglycoconjugates
1994
I-type Lectins
1995
Multiple changes in sialic acid biology during human evolution
2008
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Increasing diversity of animal lectin structures
1995
The Crystal Structure and Mode of Action of Trans-Sialidase, a Key Enzyme in Trypanosoma cruzi Pathogenesis
2002
The mannose receptor and other macrophage lectins
1992
Reassortment and Mutation of the Avian Influenza Virus Polymerase PA Subunit Overcome Species Barriers
2011 StandoutNobel
Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment
2005
A Lymnaea stagnalis gene, with sequence similarity to that of mammalian beta 1–>4-galactosyltransferases, encodes a novel UDP-GlcNAc:GlcNAc beta-R beta 1–>4-N-acetylglucosaminyltransferase.
1994
Siglecs as Immune Cell Checkpoints in Disease
2020
A Genetic Approach to Mammalian Glycan Function
2003
Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors
1997
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
A Novel Migration Pathway for Rat Dendritic Cells from the Blood: Hepatic Sinusoids–Lymph Translocation
1997
New insights into the kinetic target-guided synthesis of protein ligands
2015
Cloning and expression of Gal beta 1,3GalNAc-specific GalNAc alpha 2,6-sialyltransferase.
1994
CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics
1997
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Impact of host cell line choice on glycan profile
2017
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
Polyvalent binding to carbohydrates immobilized on an insoluble resin
1997
Macrophage Phenotype in Mice Deficient in Both Macrophage-Colony–Stimulating Factor (Op) and Apolipoprotein E
1998
Lectins: Carbohydrate-Specific Proteins That Mediate Cellular Recognition
1998 Standout
Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway
1999 StandoutNobel
A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and -F on Immune Cells
2019
CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca 2+ signaling
2013
Diversity of Microbial Sialic Acid Metabolism
2004
A mutation in human CMP-sialic acid hydroxylase occurred after theHomo-Pandivergence
1998
Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse
1993 StandoutNobel
Viewing Siglecs through the lens of tumor immunology
2017
A chemical approach for identifying O -GlcNAc-modified proteins in cells
2003 StandoutNobel
Structural Studies of Biomaterials Using Double-Quantum Solid-State NMR Spectroscopy
2003
Photoaffinity Probes for Studying Carbohydrate Biology
2012
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
METABOLIC SUBSTRATE ENGINEERING AS A TOOL FOR GLYCOBIOLOGY
2002 StandoutNobel
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Adaptive strategies of the influenza virus polymerase for replication in humans
2009 StandoutNobel
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
2000 Standout
Cutting Edge: CD43 Functions as a T Cell Counterreceptor for the Macrophage Adhesion Receptor Sialoadhesin (Siglec-1)
2001
Chemical modification of chitosan: preparation of chitosan–sialic acid branched polysaccharide hybrids
2000
Siglec‐7 tetramers characterize B‐cell subpopulations and leukemic blasts
2012
The Surface Glycoproteins of H5 Influenza Viruses Isolated from Humans, Chickens, and Wild Aquatic Birds Have Distinguishable Properties
1999
Identification and Characterization of a Novel Siglec, Siglec-7, Expressed by Human Natural Killer Cells and Monocytes
1999
Photoactivatable Crosslinking Sugars for Capturing Glycoprotein Interactions
2008
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups.
1994
Decoding the Patterns of Self and Nonself by the Innate Immune System
2002 StandoutScience
Imaging the glycome
2008 StandoutNobel
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
Preparation and Lectin Binding Property of Chitosan–Carbohydrate Conjugates
2001
Inactivation of CMP- N -acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution
2002 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air
2009
PB2 Protein of a Highly Pathogenic Avian Influenza Virus Strain A/chicken/Yamaguchi/7/2004 (H5N1) Determines Its Replication Potential in Pigs
2008
Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.
1996
Synthesis of Complex Carbohydrates and Glycoconjugates: Enzyme-Based and Programmable One-Pot Strategies
2000
Lectins as Cell Recognition Molecules
1989 Science
Identification and Molecular Cloning of P75/Airm1, a Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells
1999
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Chemical Diversity in the Sialic Acids and Related α-Keto Acids: An Evolutionary Perspective
2002
The Sialome—Far More Than the Sum of Its Parts
2010
Recognition of N -Glycolylneuraminic Acid Linked to Galactose by the α2,3 Linkage Is Associated with Intestinal Replication of Influenza A Virus in Ducks
2000
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
Siglec‐1 and ‐2 as potential biomarkers in autoimmune disease
2016
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain.
1995
Chemical Glycoproteomics
2016 StandoutNobel
Alu -mediated inactivation of the human CMP- N -acetylneuraminic acid hydroxylase gene
2001
Animal Lectins
1997
Host Range Restriction and Pathogenicity in the Context of Influenza Pandemic
2006
THE ORIGINS OF NEW PANDEMIC VIRUSES: The Acquisition of New Host Ranges by Canine Parvovirus and Influenza A Viruses
2005
Works of Sørge Kelm being referenced
Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes
2017
Sialic Acids in Molecular and Cellular Interactions
1997
SIGLEC-4 (MAG) Antagonists: From the Natural Carbohydrate Epitope to Glycomimetics
2013
Chemical and enzymatic synthesis of multivalent sialoglycopeptides
1994
C‐4 Modified Sialosides Enhance Binding to Siglec‐2 (CD22): Towards Potent Siglec Inhibitors for Immunoglycotherapy
2013
Characterization of the Sialic Acid-binding Site in Sialoadhesin by Site-directed Mutagenesis
1996
Reversible binding of sialidase-treated rat lymphocytes by homologous peritoneal macrophages
1991
Adhesion ofHelicobacter pylori strains to?-2,3-linked sialic acids
1996
Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily
1994
CMP‐N‐acetylneuraminic acid hydroxylase: the first cytosolic Rieske iron‐sulphur protein to be described in Eukarya
1996
Improved endothelial cell attachment on ePTFE vascular grafts pretreated with synthetic RGD-containing peptides
1996
A Fragment‐Based In Situ Combinatorial Approach To Identify High‐Affinity Ligands for Unknown Binding Sites
2010
Glycan specificity of myelin‐associated glycoprotein and sialoadhesin deduced from interactions with synthetic oligosaccharides
1998
Crystallographic and in Silico Analysis of the Sialoside-binding Characteristics of the Siglec Sialoadhesin
2006
Functional groups of sialic acids involved in binding to siglecs (sialoadhesins) deduced from interactions with synthetic analogues
1998
Receptor specificity of influenza virus influences severity of illness in ferrets
1995
Use of sialic acid analogues to define functional groups involved in binding to the influenza virus hemagglutinin
1992
The Galactose-Recognizing System of Rat Peritoneal Macrophages; Identification and Characterization of the Receptor Molecule
1988
Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin
2003
The Sialoadhesins ? A family of sialic acid-dependent cellular recognition molecules within the immunoglobulin superfamily
1996
Modifications of cell surface sialic acids modulate cell adhesion mediated by sialoadhesin and CD22
1994
The Amino-terminal Immunoglobulin-like Domain of Sialoadhesin Contains the Sialic Acid Binding Site
1995
Sialoadhesin binds preferentially to cells of the granulocytic lineage.
1995
Influence of Sialic Acids on the Galactose-Recognizing Receptor of Rat Peritoneal Macrophages
1990
Constitutively hyposialylated human T-lymphocyte clones in the Tn-syndrome: binding characteristics of plant and animal lectins
1996
Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG)
2007
From a Library of MAG Antagonists to Nanomolar CD22 Ligands
2011
Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules
1995
Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule.
1992
Localization of the Putative Sialic Acid-binding Site on the Immunoglobulin Superfamily Cell-surface Molecule CD22
1996
Examination of the Biological Role of the α(2→6)-Linked Sialic Acid in Gangliosides Binding to the Myelin-Associated Glycoprotein (MAG)
2009
Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains.
1994
Identification of N-acetylneuraminyl alpha 2–>3 poly-N-acetyllactosamine glycans as the receptors of sialic acid-binding Streptococcus suis strains.
1992
Molecular analysis of sialoside binding to sialoadhesin by NMR and site-directed mutagenesis
1999
The Ligand-binding Domain of CD22 Is Needed for Inhibition of the B Cell Receptor Signal, as Demonstrated by a Novel Human CD22-specific Inhibitor Compound
2002
Cluster sialoside inhibitors for influenza virus: synthesis, NMR, and biological studies.
1992
Purification of a Sialic Acid-Specific Lectin from the Indian ScorpionHeterometrus granulomanus
1986
Molecular analysis of sialoside binding to sialoadhesin by NMR and site-directed mutagenesis
1999
Design, Synthesis, and Structure−Affinity Relationships of Novel Series of Sialosides as CD22-Specific Inhibitors
2008
Sialoadhesin and related cellular recognition molecules of the immunoglobulin superfamily
1996
Low Molecular Weight Antagonists of the Myelin-Associated Glycoprotein: Synthesis, Docking, and Biological Evaluation
2010
Synthesis of cluster sialoside inhibitors for influenza virus
1991
The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
2006
Primary structure of Gal beta 1,3(4)GlcNAc alpha 2,3-sialyltransferase determined by mass spectrometry sequence analysis and molecular cloning. Evidence for a protein motif in the sialyltransferase gene family.
1992
Cloning and expression of the Gal beta 1, 3GalNAc alpha 2,3-sialyltransferase.
1992
S18.11 Potential regulatory role of sialic acid modifications in cell adhesion mediated by murine sialo-adhesin as a macrophage-restricted cell adhesion molecule
1993
Synthesis of Esterase‐resistant 9‐O‐Acetylated Polysialoside as Inhibitor of Influenza C Virus Hemagglutinin
1992
Regulation of alpha 2,3-sialyltransferase expression correlates with conversion of peanut agglutinin (PNA)+ to PNA- phenotype in developing thymocytes.
1993
Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages.
1991
Molecular Basis for the Generation in Pigs of Influenza A Viruses with Pandemic Potential
1998