Citation Impact
Citing Papers
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier
1994
Genetic Aspects of Unconventional Virus Infections: The Basis of the Virino Hypothesis
2007
Hypoxia-Dependent Retinal Toxicity of Bioreductive Anticancer Prodrugs in Mice
2000
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Chemistry and biology of prions
1992
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
1993
Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease
1991 Nature
Mutation of the Prion Protein in Libyan Jews with Creutzfeldt–Jakob Disease
1991 StandoutNobel
Glycosylinositol Phospholipid Anchors of the Scrapie and Cellular Prion Proteins Contain Sialic Acid
1992 StandoutNobel
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
1990 StandoutNobel
Catalysis for fluorination and trifluoromethylation
2011 StandoutNature
BIOLOGY AND GENETICS OF PRION DISEASES
1994
The Genomic Identity of Different Strains of Mouse Scrapie Is Expressed in Hamsters and Preserved on Reisolation in Mice
1989
A 'unified theory' of prion propagation
1991 Nature
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
To what Extent is Strain Variation Evidence for an Independent Genome in the Agent of the Transmissible Spongiform Encephalopathies?
1996
Bioreducible mustards: a paradigm for hypoxia-selective prodrugs of diffusible cytotoxins (HPDCs)
1993
Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters
1992
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
Linkage of the Scrapie-associated Fibril Protein (PrP) Gene and Sinc Using Congenic Mice and Restriction Fragment Length Polymorphism Analysis
1987
Bovine spongiform encephalopathy: detection and quantitation of fibrils, fibril protein (PrP) and vacuolation in brain
1990
Exploiting tumour hypoxia in cancer treatment
2004 Standout
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis
1991
The experimental development of bioreductive drugs and their role in cancer therapy
1993
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Genetic and Infectious Prion Diseases
1993
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours
2002
Bioreductive drugs for cancer therapy: The search for tumor specificity
1994
AQ4N: a new approach to hypoxia-activated cancer chemotherapy
2000
Transmission of bovine spongiform encephalopathy and scrapie to mice
1992
Variation in the characteristics of 10 mouse-passaged scrapie lines derived from five scrapie-positive sheep
1991
SR 4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours
1993
[PSI] and [URE3] as yeast prions
1995
Tumor-activated Prodrugs—A New Approach to Cancer Therapy
2004
Amphotericin B treatment dissociates in vivo replication of the scrapie agent from PrP accumulation
1992 Nature
Search for a Putative Scrapie Genome in Purified Prion Fractions Reveals a Paucity of Nucleic Acids
1991
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes
1993
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Chimeric prion protein expression in cultured cells and transgenic mice
1992 StandoutNobel
BIOREDUCTIVELY ACTIVATED ANTITUMORN-OXIDES: THE CASE OF AQ4N, A UNIQUE APPROACH TO HYPOXIA-ACTIVATED CANCER CHEMOTHERAPY
2002
Transmissible Mink Encephalopathy Species Barrier Effect Between Ferret and Mink: PrP Gene and Protein Analysis
1994
Bioreductive GDEPT using cytochrome P450 3A4 in combination with AQ4N
2002
NMR structures of three single-residue variants of the human prion protein
2000 StandoutNobel
Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein.
1996 StandoutNobel
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice
1997 StandoutNobel
Fluorine in medicinal chemistry
2007 Standout
Structure and polymorphism of the mouse prion protein gene.
1994 StandoutNobel
Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis
1992 StandoutNobel
Prion-inducing domain 2–114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments
1997 StandoutNobel
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
1994 StandoutNobel
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies.
1993 StandoutNobel
Hypoxia-specific cytotoxins in cancer therapy
1996
Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier.
1995
Prion protein NMR structure and familial human spongiform encephalopathies
1998 StandoutNobel
Regional mapping of prion proteins in brain.
1992 StandoutNobel
Unraveling prion diseases through molecular genetics
1989 StandoutNobel
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation
1997 StandoutNobel
Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice
1996 StandoutScience
Recent developments in the design of bioreductive drugs.
1996
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Primary structure of prion protein may modify scrapie isolate properties.
1989 StandoutNobel
Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
1996 StandoutNobel
Evidence of mitochondrial involvement in scrapie infection
1989
Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells
1994
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
Propagation of prion strains through specific conformers of the prion protein
1997 StandoutNobel
NMR solution structure of the human prion protein
2000 StandoutNobel
Unusual Topogenic Sequence Directs Prion Protein Biogenesis
1990 StandoutScienceNobel
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
1997 StandoutNobel
Enzyme-Responsive Snap-Top Covered Silica Nanocontainers
2008 StandoutNobel
Hypoxia-Selective Antitumor Agents. 16. Nitroarylmethyl Quaternary Salts as Bioreductive Prodrugs of the Alkylating Agent Mechlorethamine
2001
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains
1996 StandoutNobel
Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform.
1993
NMR structure of the bovine prion protein
2000 StandoutNobel
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.
1994 StandoutNobel
Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters.
1992 StandoutNobel
The search for scrapie agent nucleic acid
1990
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells
1995
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
Inherited prion diseases.
1994 StandoutNobel
Recombinant scrapie-like prion protein of 106 amino acids is soluble
1996 StandoutNobel
Prion protein NMR structure and species barrier for prion diseases
1997 StandoutNobel
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
1993 StandoutNobel
Prion liposomes
1990 StandoutNobel
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
1990 StandoutScienceNobel
Works of Soren Cole being referenced
True
2000
Dual function nitroimidazoles less toxic than RSU 1069: selection of candidate drugs for clinical trial (RB 6145 and/or PD 130908)
1992
Oral (po) dosing with RSU 1069 or RB 6145 maintains their potency as hypoxic cell radiosensitizers and cytotoxins but reduces systemic toxicity compared with parenteral (ip) administration in mice
1991
Fused pyrazine mono-N-oxides as bioreductive drugs III. Characterization of RB 90740 in vitro and in vivo
1995
Synthesis and evaluation of .alpha.-[[(2-haloethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanols as prodrugs of .alpha.-[(1-aziridinyl)methyl]-2-nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogs which are radiosensitizers and bioreductively activated cytotoxins
1990
Pathogenesis of scrapie is faster when infection is intraspinal instead of intracerebral
1987
THE DISPOSITION OF VORICONAZOLE IN MOUSE, RAT, RABBIT, GUINEA PIG, DOG, AND HUMAN
2003
Bioreductive drugs as post-irradiation sensitizers: Comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9
1992
Manipulation of Radiobiological Hypoxia in a Human Melanoma Xenograft to Exploit the Bioreductive Cytotoxicity of RSU-1069
1989
Dual-function 2-nitroimidazoles as hypoxic cell radiosensitizers and bioreductive cytotoxins: in vivo evaluation in KHT murine sarcomas.
1990
ChemInform Abstract: Synthesis and Evaluation of α‐(((2‐Haloethyl)amino)methyl)‐2‐ nitro‐1H‐imidazole‐1‐ethanols as Prodrugs of α‐((1‐Aziridinyl) methyl)‐2‐nitro‐1H‐imidazole‐1‐ethanol (RSU‐1069) and Its Analogues which are Radiosensitizers and Bioreductively Activated Cytotoxins.
1991
Induction of hypoxia in normal and malignant tissues by changing the oxygen affinity of hemoglobin—Implications for theraphy
1986
Dual-Function 2-Nitroimidazoles as Hypoxic Cell Radiosensitizers and Bioreductive Cytotoxins: In Vivo Evaluation in KHT Murine Sarcomas
1990
PATHOGENESIS OF MOUSE SCRAPIE: DYNAMICS OF VACUOLATION IN BRAIN AND SPINAL CORD AFTER INTRAPERITONEAL INFECTION
1985
TRANSMISSIBLE MINK ENCEPHALOPATHY (TME) IN CHINESE HAMSTERS: IDENTIFICATION OF TWO STRAINS OF TME AND COMPARISONS WITH SCRAPIE
1986
Temporary and Permanent Modifications to a Single Strain of Mouse Scrapie on Transmission to Rats and Hamsters
1987
Manipulation of oxygenation in a human tumour xenograft with BW12C or hydralazine : effects on responses to radiation and to the bioreductive cytotoxicity of misonidazole or RSU-1069
1989