Standout Papers
Citation Impact
Citing Papers
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
A TOG:αβ-tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
2012 Science
Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion
2011
Bulk RNA degradation by nitrogen starvation‐induced autophagy in yeast
2014 StandoutNobel
Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met
1999
CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor.
1995
CD44 is required for two consecutive steps in HGF/c-Met signaling
2002
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
2015 StandoutNobel
The role of chemokines in the regulation of dendritic cell trafficking
1999
Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis
2012 StandoutNobel
Antisense Transcription Controls Cell Fate in Saccharomyces cerevisiae
2006
Identification of CD44 Residues Important for Hyaluronan Binding and Delineation of the Binding Site
1998
Organization and Assembly of the TRAPPII Complex
2011
CD44: From adhesion molecules to signalling regulators
2003 Standout
Hyaluronan Metabolism in Skin
1994
Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family
2014
Variant Exons v6 and v7 Together Expand the Repertoire of Glycosaminoglycans Bound by CD44
1997
HA receptors: Regulators of signalling to the cytoskeleton
1996
Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates
2011
Genome-wide detection of tissue-specific alternative splicing in the human transcriptome
2002
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Structural basis of starvation-induced assembly of the autophagy initiation complex
2014 StandoutNobel
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
The BRG-1 Subunit of the SWI/SNF Complex Regulates CD44 Expression
2001
Binding and degradation of hyaluronan by human breast cancer cell lines expressing different forms of CD44: Correlation with invasive potential
1994
Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression
1994
Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion
1999
CD44: A Multitude of Isoforms with Diverse Functions
1993
Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of α‐mannosidase under nitrogen starvation conditions
2014 StandoutNobel
Regulation of alternative pre-mRNA splicing by the ERK MAP-kinase pathway
2001
The generation of diversity and pattern in animal development
1992 StandoutNobel
Rho-kinase (ROK) promotes CD44v3,8-10-ankyrin interaction and tumor cell migration in metastatic breast cancer cells
1999
Antibody‐induced activation of the hyaluronan receptor function of CD44 requires multivalent binding by antibody
1993
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
New Insights into the Mechanisms of Cytomotive Actin and Tubulin Filaments
2011
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
The CD44 Proteins in Embryonic Development and in Cancer
1996
Atg12–Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site
2013 StandoutNobel
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Regulated CD44 Cleavage under the Control of Protein Kinase C, Calcium Influx, and the Rho Family of Small G Proteins
1999
ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery
2014
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
2001
Lap3 is a selective target of autophagy in yeast, Saccharomyces cerevisiae
2008 StandoutNobel
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
Proteomic Profiling of Autophagosome Cargo in Saccharomyces cerevisiae
2014 StandoutNobel
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Ras Oncoprotein Induces CD44 Cleavage through Phosphoinositide 3-OH Kinase and the Rho Family of Small G Proteins
2000
Expression of CD44 in Apc and TcfMutant Mice Implies Regulation by the WNT Pathway
1999
Proteolytic Cleavage of the CD44 Adhesion Molecule in Multiple Human Tumors
2002
A LOV2 Domain-Based Optogenetic Tool to Control Protein Degradation and Cellular Function
2013
The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin
2017
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Characterization of a Functional Hyaluronan-Binding Domain from the Human CD44 Molecule Expressed inEscherichia coli
1998
Signaling through CD44 Is Mediated by Tyrosine Kinases
1996
Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons
1992
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration
1999
A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth
1998
Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy
2008
Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells
1999
The sweet and sour of cancer: glycans as novel therapeutic targets
2005
Localization of Atg3 to autophagy‐related membranes and its enhancement by the Atg8‐family interacting motif to promote expansion of the membranes
2015 StandoutNobel
Glycosylation in cancer: mechanisms and clinical implications
2015 Standout
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery
2006
Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site
2012 StandoutNobel
The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan.
1992
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.
1994
CD44 is the major peanut lectin-binding glycoprotein of human epidermal keratinocytes and plays a role in intercellular adhesion
1995
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
AP-1-Mediated Invasion Requires Increased Expression of the Hyaluronan Receptor CD44
1997
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Coupling of Osteopontin and Its Cell Surface Receptor CD44 to the Cell Survival Response Elicited by Interleukin-3 or Granulocyte-Macrophage Colony-Stimulating Factor
2000
Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44.
1993
Phosphorylation of CD44 in vivo requires both Ser323 and Ser325, but does not regulate membrane localization or cytoskeletal interaction in epithelial cells.
1992
Hrr25 triggers selective autophagy–related pathways by phosphorylating receptor proteins
2014 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
Forms and functions of CD44
1998
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
2000 Standout
Distinct effects of two CD44 isoforms on tumor growth in vivo.
1991
Layilin, a Novel Integral Membrane Protein, Is a Hyaluronan Receptor
2001
A link between ras and metastatic behavior of tumor cells : ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells
1993
CD44 Regulates Hematopoietic Progenitor Distribution, Granuloma Formation, and Tumorigenicity
1997
Tumour necrosis factor-alpha is required for accumulation of dendritic cells in draining lymph nodes and for optimal contact sensitization.
1995
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
2012 StandoutNobel
CD44-Deficient Mice Develop Normally with Changes in Subpopulations and Recirculation of Lymphocyte Subsets
1999
CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis.
1999
Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway
2001
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts
1995
CD44 exhibits a cell type dependent interaction with Triton X-100 insoluble, lipid rich, plasma membrane domains
1995
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
2015 StandoutNobel
Induction of Apoptosis of Metastatic Mammary Carcinoma Cells In Vivo by Disruption of Tumor Cell Surface CD44 Function
1997
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.
1994
Expression of CD44 is repressed in neuroblastoma cells.
1991 Nobel
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Imaging the glycome
2008 StandoutNobel
The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts.
1993
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.
2000 Standout
Peroxisomal Membrane Proteins Insert into the Endoplasmic Reticulum
2010
Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.
1992
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity
2013 StandoutNobel
Centrosomes are autocatalytic droplets of pericentriolar material organized by centrioles
2014
Absence of the CD44 gene prevents sarcoma metastasis.
2002
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Analysis of iron–sulfur protein maturation in eukaryotes
2009
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation.
1997
Participation in Normal Immune Responses of a Metastasis-Inducing Splice Variant of CD44
1992 Science
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Chemical Glycoproteomics
2016 StandoutNobel
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
1994 Standout
An Essential Role for CD44 Variant Isoforms in Epidermal Langerhans Cell and Blood Dendritic Cell Function
1997
Works of Simone Reber being referenced
A versatile toolbox for PCR‐based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes
2004 Standout
Retardation of metastatic tumor growth after immunization with metastasis‐specific monoclonal antibodies
1990
A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
1991
Dynamic Organization of the Actin Cytoskeleton During Meiosis and Spore Formation in Budding Yeast
2006
Prevention of tumor metastasis formation by anti-variant CD44.
1993
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules
2013
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region
2011