Citation Impact
Citing Papers
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
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β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
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High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Functional specialization of β-arrestin interactions revealed by proteomic analysis
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Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
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A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination
2011
Simultaneous prediction of protein folding and docking at high resolution
2009 StandoutNobel
A Novel Endocytic Mechanism of Epidermal Growth Factor Receptor Sequestration and Internalization
2006
Ubiquitin-binding domains
2006
Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development
2007
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
UAF1 Is a Subunit of Multiple Deubiquitinating Enzyme Complexes
2008
Structural Basis for Ubiquitin Recognition by the Otu1 Ovarian Tumor Domain Protein
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Cargo Selection in Vesicular Transport: The Making and Breaking of a Coat
2002
Distinct Dynamics of Endocytic Clathrin-Coated Pits and Coated Plaques
2009
Ubiquitin-binding domains
2005
Ubiquitin-binding domains — from structures to functions
2009
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Structure and functional interactions of the Tsg101 UEV domain
2002
The closure of Pak1‐dependent macropinosomes requires the phosphorylation of CtBP1/BARS
2008
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
The multiple faces of caveolae
2007
Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination
2003 StandoutNobel
Regulation of Translesion Synthesis DNA Polymerase η by Monoubiquitination
2010
Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules
2006
The interplay between clathrin-coated vesicles and cell signalling
2007
Actin in the endocytic pathway: From yeast to mammals
2008
Derailed endocytosis: an emerging feature of cancer
2008
Receptor downregulation and multivesicular-body sorting
2002
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Building ubiquitin chains: E2 enzymes at work
2009
Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7
2008
Activation of the Endosome-Associated Ubiquitin Isopeptidase AMSH by STAM, a Component of the Multivesicular Body-Sorting Machinery
2006
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Mature Dendritic Cells Respond to SDF-1, but not to Several β-Chemokines
1998
Differential Nucleocytoplasmic Shuttling of β-Arrestins
2002
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles
2003 StandoutNobel
Pathways of clathrin-independent endocytosis
2007
Solution structure of Vps27 UIM-ubiquitin complex important for endosomal sorting and receptor downregulation
2003
A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis
2011
TGFβ signalling in context
2012 Standout
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
2009
Crystal Structure of a Josephin-Ubiquitin Complex
2010
Actin in membrane trafficking
2007
A Deubiquitinating Enzyme UBPY Regulates the Level of Protein Ubiquitination on Endosomes
2006
Proliferation Versus Migration in Platelet-derived Growth Factor Signaling
2008
Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
2003
Exposure to bacterial products renders macrophages highly susceptible to T-tropic HIV-1.
1998
Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome
2006
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
E3-Independent Monoubiquitination of Ubiquitin-Binding Proteins
2007
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
2009 Nature
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Chemokine Receptor Regulation and HIV Type 1 Tropism in Monocyte-Macrophages
1998
The endocytic matrix
2010 Nature
TAB2 and TAB3 Activate the NF-κB Pathway through Binding to Polyubiquitin Chains
2004
Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation
2007 StandoutNobel
Role of CD4 and CCR5 Levels in the Susceptibility of Primary Macrophages to Infection by CCR5-Dependent HIV Type 1 Isolates
1999
Rab GTPases as coordinators of vesicle traffic
2009 Standout
Clathrin‐Coated Pits: Vive La Différence?
2007
EGF–ERBB signalling: towards the systems level
2006 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Distinct monoubiquitin signals in receptor endocytosis
2003
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
2008
Integrins: masters and slaves of endocytic transport
2009
BAR, F-BAR (EFC) and ENTH/ANTH domains in the regulation of membrane–cytosol interfaces and membrane curvature
2006
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase
2007
The Structure of the APPBP1-UBA3-NEDD8-ATP Complex Reveals the Basis for Selective Ubiquitin-like Protein Activation by an E1
2003
STAM and Hrs Are Subunits of a Multivalent Ubiquitin-binding Complex on Early Endosomes
2003
Contribution of Lysine 11-linked Ubiquitination to MIR2-mediated Major Histocompatibility Complex Class I Internalization
2010
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Role of ubiquitin- and Ubl-binding proteins in cell signaling
2007
The Deubiquitinating Enzyme Ataxin-3, a Polyglutamine Disease Protein, Edits Lys63 Linkages in Mixed Linkage Ubiquitin Chains
2008
Characterization of ubiquitin and ubiquitin‐like‐protein isopeptidase activities
2008
Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly
2006
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
NEMO specifically recognizes K63‐linked poly‐ubiquitin chains through a new bipartite ubiquitin‐binding domain
2009
Deubiquitylation and regulation of the immune response
2008
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Fiji: an open-source platform for biological-image analysis
2012 Standout
The MIT Domain of UBPY Constitutes a CHMP Binding and Endosomal Localization Signal Required for Efficient Epidermal Growth Factor Receptor Degradation
2007
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
2006
The Ubiquitin Binding Region of the Smurf HECT Domain Facilitates Polyubiquitylation and Binding of Ubiquitylated Substrates
2009
Linkage-Specific Avidity Defines the Lysine 63-Linked Polyubiquitin-Binding Preference of Rap80
2009
Structure validation of the Josephin domain of ataxin-3: Conclusive evidence for an open conformation
2006
Cargo recognition during clathrin-mediated endocytosis: a team effort
2004
Endocytosis: the DUB version
2006
The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin
2006
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Role of lipids and actin in the formation of clathrin-coated pits
2006
Ubiquitin Chains Are Remodeled at the Proteasome by Opposing Ubiquitin Ligase and Deubiquitinating Activities
2006
Endocytosis and signalling: intertwining molecular networks
2009
Making and breaking contacts: the cellular biology of cadherin regulation
2007
Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells
2005
Differential Regulation of EGF Receptor Internalization and Degradation by Multiubiquitination within the Kinase Domain
2006
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
2011 Standout
Intestinal macrophages display reduced permissiveness to human immunodeficiency virus 1 and decreased surface CCR5
1999
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity
2003
Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
2010
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
2009
Subcellular Localization of β-Arrestins Is Determined by Their Intact N Domain and the Nuclear Export Signal at the C Terminus
2003
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
Mechanism and Consequences for Paralog-Specific Sumoylation of Ubiquitin-Specific Protease 25
2008
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
2009
α-Synuclein and Parkin Contribute to the Assembly of Ubiquitin Lysine 63-linked Multiubiquitin Chains
2005
TTP Specifically Regulates the Internalization of the Transferrin Receptor
2005
The ubiquitous role of ubiquitin in the DNA damage response
2010
Ubiquitin and ubiquitin-like proteins as multifunctional signals
2005
Clathrin anchors deubiquitinating enzymes, AMSH and AMSH‐like protein, on early endosomes
2006
Systems survey of endocytosis by multiparametric image analysis
2010 Nature
E3 ubiquitin ligases as T cell anergy factors
2004
IL-13 and TNF-α inhibit dual-tropic HIV-1 in primary macrophages by reduction of surface expression of CD4, chemokine receptors CCR5, CXCR4 and post-entry viral gene expression
2000
Analysis of Clathrin-mediated Endocytosis of Epidermal Growth Factor Receptor by RNA Interference
2004
The ESCRT Pathway
2011
Cells of the Monocyte-Macrophage Lineage and Pathogenesis of HIV-1 Infection
1999
Regulation of clathrin‐mediated endocytosis by p53
2008
The Comparative Proteomics of Ubiquitination in Mouse
2003
SCA3: Neurological features, pathogenesis and animal models
2008
Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin‐3
2009
Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
2003
Driving membrane curvature in clathrin-dependent and clathrin-independent endocytosis
2009
EGFR endocytosis requires its kinase activity and N-terminal transmembrane dimerization motif
2013
The Ubiquitin Isopeptidase UBPY Regulates Endosomal Ubiquitin Dynamics and Is Essential for Receptor Down-regulation
2006
Clathrin‐Dependent Mechanisms of G Protein‐coupled Receptor Endocytosis
2007
Regulation of death receptor signaling by the ubiquitin system
2009
Regulation of ubiquitin-binding proteins by monoubiquitination
2006
The crosstalk between microtubules, actin and membranes shapes cell division
2020
EGF receptor ubiquitination is not necessary for its internalization
2007
Atypical ubiquitin chains: new molecular signals
2008
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Regulation of chemokine/cytokine network during in vitro differentiation and HIV-1 infection of human monocytes: possible importance in the pathogenesis of AIDS
2000
β-Chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans
1998 Nature
Control of AMPK-related kinases by USP9X and atypical Lys29/Lys33-linked polyubiquitin chains
2008
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Regulation of G Protein and Mitogen-Activated Protein Kinase Signaling by Ubiquitination
2006
Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus
2008
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive β-chemokines
1998
Protein partners of deubiquitinating enzymes
2008
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection
2002
Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling
2007 Science
Novel function of β-arrestin2 in the nucleus of mature spermatozoa
2006
Clathrin-mediated endocytosis in AP-2–depleted cells
2003
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution
2008 Science
Activation-Induced Resistance of Human Macrophages to HIV-1 Infection In Vitro
1999
Cell Signaling in Space and Time: Where Proteins Come Together and When They’re Apart
2009 Science
Lipopolysaccharide Inhibits HIV-1 Infection of Monocyte- Derived Macrophages Through Direct and Sustained Down-Regulation of CC Chemokine Receptor 5
2000
Stabilization of the E3 Ubiquitin Ligase Nrdp1 by the Deubiquitinating Enzyme USP8
2004
ADAPTORS FOR CLATHRIN COATS: Structure and Function
2004
Depletion of TSG101 forms a mammalian `Class E' compartment: a multicisternal early endosome with multiple sorting defects
2005
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
Opposite Fate of Endocytosed CCR7 and Its Ligands: Recycling versus Degradation
2006
RING Domain E3 Ubiquitin Ligases
2009 Standout
AMSH is an endosome-associated ubiquitin isopeptidase
2004
Interferon γ and interleukin 6 modulate the susceptibility of macrophages to human immunodeficiency virus type 1 infection
2000
Assembly of Cell Regulatory Systems Through Protein Interaction Domains
2003 Science
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells
2004
Chemokine immunobiology in HIV-1 pathogenesis
1999
Early-Arriving Syp1p and Ede1p Function in Endocytic Site Placement and Formation in Budding Yeast
2009
Regulation of Epidermal Growth Factor Receptor Down-Regulation by UBPY-mediated Deubiquitination at Endosomes
2005
Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice
2009
Modeling the Structural Basis of Human CCR5 Chemokine Receptor Function: From Homology Model Building and Molecular Dynamics Validation to Agonist and Antagonist Docking
2006
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Fcγ Receptor-Mediated Suppression of Human Immunodeficiency Virus Type 1 Replication in Primary Human Macrophages
2003 StandoutNobel
Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins
2003
Get Off My Back! Rapid Receptor Internalization through Circular Dorsal Ruffles
2006
The Ubiquitin Code
2012 Standout
Regulation of Human Immunodeficiency Virus Type 1 Infection, β-Chemokine Production, and CCR5 Expression in CD40L-Stimulated Macrophages: Immune Control of Viral Entry
2001
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Seven-Transmembrane Receptors and Ubiquitination
2007
Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1
2006
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Mechanisms of Endocytosis
2009 Standout
Structure and function of a HECT domain ubiquitin‐binding site
2011
Neuregulin-Induced ErbB3 Downregulation Is Mediated by a Protein Stability Cascade Involving the E3 Ubiquitin Ligase Nrdp1
2007
Bending a membrane: How clathrin affects budding
2006
Structure of the A20 OTU domain and mechanistic insights into deubiquitination
2007
Works of Simona Polo being referenced
Reticulon 3–dependent ER-PM contact sites control EGFR nonclathrin endocytosis
2017 Science
Clathrin-independent endocytosis of ubiquitinated cargos
2005
Differential Nucleocytoplasmic Trafficking between the Related Endocytic Proteins Eps15 and Eps15R
2002
Signaling Through Monoubiquitination
2004
When ubiquitin meets E-cadherin: Plasticity of the epithelial cellular barrier
2018
Endocytosis Conducts the Cell Signaling Orchestra
2006
When ubiquitin meets ubiquitin receptors: a signalling connection
2003
Molecular mechanisms of coupled monoubiquitination
2006
Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES.
2001
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins
2002 Nature
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
2003
Endocytosis and cancer
2004
Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation
2008
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin
2006
USP15 is a deubiquitylating enzyme for receptor-activated SMADs
2011
Ubiquitin in trafficking: The network at work
2008
EH and UIM: Endocytosis and More
2003
Nucleocytoplasmic Shuttling of Endocytic Proteins
2001
Rapid Ca2+-dependent decrease of protein ubiquitination at synapses
2003
CXCR4 is a functional coreceptor for infection of human macrophages by CXCR4-dependent primary HIV-1 isolates.
1998
Deubiquitinating function of ataxin-3: Insights from the solution structure of the Josephin domain
2005
C–C Chemokines Released by Lipopolysaccharide (LPS)-stimulated Human Macrophages Suppress HIV-1 Infection in Both Macrophages and T Cells
1997
N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits
2005
Cutting Edge: CXCR4 Is a Functional Coreceptor for Infection of Human Macrophages by CXCR4-Dependent Primary HIV-1 Isolates
1998
Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation
2011
Endocytosis and Signaling: Cell Logistics Shape the Eukaryotic Cell Plan
2012