Simon Völkl

Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics

The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy

Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists

mTOR inhibitors effects on regulatory T cells and on dendritic cells

Transcription Factor Bhlhe40 in Immunity and Autoimmunity

Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity

Macrophages in immunoregulation and therapeutics

Functional Characterization of Polymorphisms in the Kidney Enhancer of the Human Renin Gene

A unique chromatin signature uncovers early developmental enhancers in humans

mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model

Understanding the Intersections between Metabolism and Cancer Biology

CD3+CD4-CD8- (Double-Negative) T Cells in Inflammation, Immune Disorders and Cancer

Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity

Control of foreign Ag‐specific Ab responses by Treg and Tfr

Myeloid-Derived Suppressor Cells and Mesenchymal Stem/Stromal Cells in Myeloid Malignancies

Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling

CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity

Human Double-Negative Regulatory T-Cells Induce a Metabolic and Functional Switch in Effector T-Cells by Suppressing mTOR Activity

Suppressive effects of tumor cell-derived 5′-deoxy-5′-methylthioadenosine on human T cells

CD33/CD3-bispecific T-cell engaging (BiTE®) antibody construct targets monocytic AML myeloid-derived suppressor cells

BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease

Tumor Necrosis Factor-α Activates NFκB to Inhibit Renin Transcription by Targeting cAMP-responsive Element

IL-7 Abrogates the Immunosuppressive Function of Human Double-Negative T Cells by Activating Akt/mTOR Signaling