Citation Impact

Citing Papers

Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Oligomerization of the integrin αIIbβ3: Roles of the transmembrane and cytoplasmic domains
2001
Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1 H‐CEST
2016
Formation, chemical evolution and solidification of the dense liquid phase of calcium (bi)carbonate
2024 StandoutNobel
Stacked Sets of Parallel, In-register β-Strands of β2-Microglobulin in Amyloid Fibrils Revealed by Site-directed Spin Labeling and Chemical Labeling
2010
The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration
2018
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors
2003
Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker
2012 Standout
The Single Transmembrane Domains of ErbB Receptors Self-associate in Cell Membranes
2002
The role of HER2 in cancer therapy and targeted drug delivery
2010
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
Recombinant self-assembling peptides as biomaterials for tissue engineering
2010
ERBB receptors and cancer: the complexity of targeted inhibitors
2005 Standout
Engineering synthetic biomolecular condensates
2023
Unraveling the meaning of chemical shifts in protein NMR
2017
Multistate and functional protein design using RoseTTAFold sequence space diffusion
2024 StandoutNobel
Methods for Physical Characterization of Phase-Separated Bodies and Membrane-less Organelles
2018
Coarse-grained molecular dynamics simulations of membrane proteins and peptides
2006
HIV Accessory Genes Vif and Vpu
2007
Role of Side-Chain Conformational Entropy in Transmembrane Helix Dimerization of Glycophorin A
2003
Structural and dynamical characterization of tubular HIV‐1 capsid protein assemblies by solid state nuclear magnetic resonance and electron microscopy
2010
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis
2008 StandoutNobel
Structural Characteristics of α-Synuclein Oligomers
2016
On the Interpretation of Force-Induced Unfolding Studies of Membrane Proteins Using Fast Simulations
2019 StandoutNobel
Revisiting 1HN CPMG relaxation dispersion experiments: a simple modification can eliminate large artifacts
2019
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Chemical shift-based methods in NMR structure determination
2018
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3
2009 StandoutNobel
Delicate Balance between Functionally Required Flexibility and Aggregation Risk in a β-Rich Protein
2013
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
2021
The Dynamic Orientation of Membrane-Bound Peptides: Bridging Simulations and Experiments
2007
EGF–ERBB signalling: towards the systems level
2006 Standout
The Science of Antibiotic Discovery
2020 Standout
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Simulation Studies of Protein-Induced Bilayer Deformations, and Lipid-Induced Protein Tilting, on a Mesoscopic Model for Lipid Bilayers with Embedded Proteins
2005
Energetics and dynamics of SNAREpin folding across lipid bilayers
2007 StandoutNobel
Computational design of self-assembling cyclic protein homo-oligomers
2016 StandoutNobel
SNAREs — engines for membrane fusion
2006 Standout
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice
2019
De Novo Design and Experimental Characterization of Ultrashort Self-Associating Peptides
2014
Viroporins: structure and biological functions
2012
Tilt Angles of Transmembrane Model Peptides in Oriented and Non-Oriented Lipid Bilayers as Determined by 2H Solid-State NMR
2004
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints
2016
The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles
2013 StandoutNobel
De novo design of a non-local β-sheet protein with high stability and accuracy
2018 StandoutNobel
The Amyloid State of Proteins in Human Diseases
2012 Standout
Design of amyloidogenic peptide traps
2024 StandoutNobel
A Diversity of Assembly Mechanisms of a Generic Amyloid Fold
2011
Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers
2018
Production of self-assembling biomaterials for tissue engineering
2009
The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production
2015 StandoutNobel
BST-2/tetherin: Structural biology, viral antagonism, and immunobiology of a potent host antiviral factor
2012
De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy
2015 StandoutNobel
The p7 Protein of Hepatitis C Virus Forms Structurally Plastic, Minimalist Ion Channels
2012
Protein aggregation processes: In search of the mechanism
2007
Molecular Dynamics Simulations of Model Trans-Membrane Peptides in Lipid Bilayers: A Systematic Investigation of Hydrophobic Mismatch
2006
Integrins
2002 Standout
Exploring the conformational space of Vpu from HIV‐1: A versatile adaptable protein
2008
Epidermal growth factor receptor (EGFR) signaling in cancer
2005 Standout
Bioproduction and characterization of a pH responsive self‐assembling peptide
2009
Mechanical Coupling via the Membrane Fusion SNARE Protein Syntaxin 1A: A Molecular Dynamics Study
2003
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
2021 StandoutNobel
Modelling of proteins in membranes
2006
The amyloid state and its association with protein misfolding diseases
2014 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy
2009
Visualizing Side Chains of Invisible Protein Conformers by Solution NMR
2013
A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations
2018 StandoutNobel
Phase to Phase with TDP-43
2017
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Customized Reversible Stapling for Selective Delivery of Bioactive Peptides
2022
Supramolecular Polymerization
2009 Standout
The Supramolecular Chemistry of β-Sheets
2013
Computer Simulation of Liquids
2017 Standout
Using 19F NMR to Probe Biological Interactions of Proteins and Peptides
2014
Solid-State NMR Studies of Amyloid Fibril Structure
2011
Proteinase K-Catalyzed Synthesis of Linear and Star Oligo(l-phenylalanine) Conjugates
2013
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
The MARTINI Coarse-Grained Force Field: Extension to Proteins
2008 Standout
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
On the Orientation of a Designed Transmembrane Peptide:  Toward the Right Tilt Angle?
2007
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Mesoscopic models of biological membranes
2006
Force-dependent switch in protein unfolding pathways and transition-state movements
2016
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Energy Landscapes as a Tool to Integrate GPCR Structure, Dynamics, and Function
2010 StandoutNobel
The α-Helical C-Terminal Domain of Full-Length Recombinant PrP Converts to an In-Register Parallel β-Sheet Structure in PrP Fibrils: Evidence from Solid State Nuclear Magnetic Resonance
2010
Measurement of Proton Chemical Shifts in Invisible States of Slowly Exchanging Protein Systems by Chemical Exchange Saturation Transfer
2012
How Protein Transmembrane Segments Sense the Lipid Environment
2007
Mechanisms of Endocytosis
2009 Standout
Multiple Unbiased Prospective Screens Identify TRP Channels and Their Conserved Gating Elements
2008 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience

Works of Simon Sharpe being referenced

Direct observation of structure and dynamics during phase separation of an elastomeric protein
2017
Dynamic Equilibria between Monomeric and Oligomeric Misfolded States of the Mammalian Prion Protein Measured by 19 F NMR
2013
Structure of an Intermediate State in Protein Folding and Aggregation
2012 Science
Expression and Membrane Assembly of a Transmembrane Region from Neu
2000
Val659→Glu Mutation within the Transmembrane Domain of ErbB-2:  Effects Measured by 2H NMR in Fluid Phospholipid Bilayers
2000
Structural Implications of a Val→Glu Mutation in Transmembrane Peptides from the EGF Receptor
2001
Expression and purification of a recombinant peptide from the Alzheimer’s β-amyloid protein for solid-state NMR
2005
FRET Analysis of the Promiscuous yet Specific Interactions of the HIV-1 Vpu Transmembrane Domain
2017
Core Structure of Amyloid Fibrils Formed by Residues 106–126 of the Human Prion Protein
2009
Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides
2017
The Mechanism of Membrane Disruption by Cytotoxic Amyloid Oligomers Formed by Prion Protein(106–126) Is Dependent on Bilayer Composition
2014
Organization of Model Helical Peptides in Lipid Bilayers: Insight into the Behavior of Single-Span Protein Transmembrane Domains
2002
Molecular Dynamics Simulation of Transmembrane Polypeptide Orientational Fluctuations
2004
Oligomerization state and supramolecular structure of the HIV‐1 Vpu protein transmembrane segment in phospholipid bilayers
2010
Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses
2016
Role of Liquid–Liquid Phase Separation in Assembly of Elastin and Other Extracellular Matrix Proteins
2018
Dimerization of the Transmembrane Domain of Human Tetherin in Membrane Mimetic Environments
2012
Solid-State NMR Characterization of Autofluorescent Fibrils Formed by the Elastin-Derived Peptide GVGVAGVG
2011
Solid-State NMR Yields Structural Constraints on the V3 Loop from HIV-1 Gp120 Bound to the 447-52D Antibody Fv Fragment
2004
Probing Dynamic Conformations of the High-Molecular-Weight αB-Crystallin Heat Shock Protein Ensemble by NMR Spectroscopy
2012
Structural Properties and Dynamic Behavior of Nonfibrillar Oligomers Formed by PrP(106−126)
2010
Structure and Dynamics of the HIV-1 Vpu Transmembrane Domain Revealed by Solid-State NMR with Magic-Angle Spinning
2005
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