Citation Impact

Citing Papers

Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
2009
The role of FUS gene variants in neurodegenerative diseases
2014
Limelight on Alpha-Synuclein: Pathological and Mechanistic Implications in Neurodegeneration
2013
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Parkinson disease
2017 Standout
Olfaction in Parkinson's disease and related disorders
2011
Recent advances in our understanding of neurodegeneration
2009
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
2013
Arginine methylation next to the PY‐NLS modulates Transportin binding and nuclear import of FUS
2012
Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry
2011
Mechanism and medical implications of mammalian autophagy
2018 Standout
The changing scene of amyotrophic lateral sclerosis
2013
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
The role of autophagy in neurodegenerative disease
2013 Standout
Cellular strategies for controlling protein aggregation
2010
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
Post-mortem MRI versus conventional autopsy in fetuses and children: a prospective validation study
2013
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Hallmarks of aging: An expanding universe
2023 Standout
The Levinthal paradox of the interactome
2011
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology
2014
Crohn's disease
2012 Standout
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
2012
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Genetic Animal Models of Parkinson's Disease
2010
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis
2016
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
2010
Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes
2013
Autophagy: Renovation of Cells and Tissues
2011 Standout
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease
2009
Exploring the link between glucocerebrosidase mutations and parkinsonism
2011
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
2015 Standout
RNA-binding proteins with prion-like domains in ALS and FTLD-U
2011
Parkinson's disease
2015 Standout
Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
2015 Nobel
Autophagy in Human Health and Disease
2013 Standout
Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
2012
A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components
2010
Mechanisms and functions of Nrf2 signaling in Drosophila
2015
PCR assays for detection of human astroviruses: In silico evaluation and design, and in vitro application to samples collected from patients in the Netherlands
2018
Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS
2011
Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy
2009
Mechanisms of mitophagy
2010 Standout
Intranuclear Aggregation of Mutant FUS/TLS as a Molecular Pathomechanism of Amyotrophic Lateral Sclerosis
2013
mTOR Signaling in Epilepsy: Insights from Malformations of Cortical Development
2015
Distinct RolesIn Vivofor the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein
2011
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
2017 Standout
Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism
2015
Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
2012 Standout
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis
2010
Non-motor features of Parkinson disease
2017 Standout
The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
2012
The role of iron in brain ageing and neurodegenerative disorders
2014 Standout
Regulation of proteasome assembly and activity in health and disease
2018
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
2012
Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship
2012
Endosome maturation
2011 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Linking pathways in the developing and aging brain with neurodegeneration
2014
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
2014
The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2
2020 Standout
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
The amyloid state and its association with protein misfolding diseases
2014 Standout
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
2013
Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis
2014 Standout
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
2009
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
The Proteasome and Oxidative Stress in Alzheimer's Disease
2016
The Ubiquitin-Proteasome System in Neurodegeneration
2014
Does Impairment of the Ubiquitin-Proteasome System or the Autophagy-Lysosome Pathway Predispose Individuals to Neurodegenerative Disorders such as Parkinson's Disease?
2010
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
KEGG: integrating viruses and cellular organisms
2020 Standout
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
2019 StandoutNobel
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
2016 StandoutNobel
Ubiquitin and Parkinson's disease through the looking glass of genetics
2017
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Liquid-Liquid Phase Separation in Biology
2014 Standout
SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner
2011 Standout
Neuronal‐specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age‐related cognitive decline
2019
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 Standout
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020

Works of Simon Paine being referenced

Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations
2010
Approach to the post-mortem investigation of neurodegenerative diseases: from diagnosis to research
2011
mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis
2013
Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients
2015
Pale Body-Like Inclusion Formation and Neurodegeneration following Depletion of 26S Proteasomes in Mouse Brain Neurones are Independent of α-Synuclein
2013
Is malfunction of the ubiquitin proteasome system the primary cause of α-synucleinopathies and other chronic human neurodegenerative disease?
2008
Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies
2008
Role of routine neuropathological examination for determining cause of death in sudden unexpected deaths in infancy (SUDI)
2011
The UPS and autophagy in chronic neurodegenerative disease: Six of one and half a dozen of the other—Or not?
2009
Assembly, structure, and function of the 26S proteasome
2010
Atypical Progressive Multifocal Leukoencephalopathy Associated With an Unusual JC Polyomavirus Mutation
2009
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