Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Immunomodulatory Function of Interleukin 28B During Primary Infection With Cytomegalovirus
2014 StandoutNobel
An Important Role for Type III Interferon (IFN-λ/IL-28) in TLR-Induced Antiviral Activity
2008
The Lambda Interferons: Guardians of the Immune–Epithelial Interface and the T-helper 2 Response
2010
Interferon Lambda Genetic Polymorphisms and Viral Infection: The Tip of the Iceberg?
2013
Importance of Cytokines in Murine Allergic Airway Disease and Human Asthma
2010
Involvement of Toll-like Receptor 3 in the Immune Response of Lung Epithelial Cells to Double-stranded RNA and Influenza A Virus
2004
IL‐28A (IFN‐λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease
2011
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2007 Standout
Interferon-λ: Immune Functions at Barrier Surfaces and Beyond
2015
Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness
2017
Epithelium dysfunction in asthma
2007
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease
2008
Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease
2010 Standout
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Respiratory virus induction of alpha‐, beta‐ and lambda‐interferons in bronchial epithelial cells and peripheral blood mononuclear cells
2009
RIG-I-like receptors: their regulation and roles in RNA sensing
2020
SOCS proteins, cytokine signalling and immune regulation
2007 Standout
The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
2013 StandoutNobel
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
2004 Standout
Cytosolic surveillance and antiviral immunity
2011
Human interferon-λ3 is a potent member of the type III interferon family
2008
Chronic obstructive pulmonary disease
2003
The Role of Genomic Data in the Discovery, Annotation and Evolutionary Interpretation of the Interferon-Lambda Family
2009
LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs
2011
Type I interferons in infectious disease
2015 Standout
Vitamin E and Respiratory Tract Infections in Elderly Nursing Home Residents
2004
Epithelium: At the interface of innate and adaptive immune responses
2007
Cancer immunotherapy via dendritic cells
2012 Standout
IgE and mast cells in allergic disease
2012 Standout
Immunogenic cell death in cancer and infectious disease
2016 Standout
CFTR, Mucins, and Mucus Obstruction in Cystic Fibrosis
2012
Pharmacology and therapeutic potential of interferons
2012
COPD exacerbations: defining their cause and prevention
2007
The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity
2013
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
2003 StandoutNobel
Complement: a key system for immune surveillance and homeostasis
2010 Standout
Respiratory virus shedding in exhaled breath and efficacy of face masks
2020 Standout
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
The sentinel role of the airway epithelium in asthma pathogenesis
2011
Asthma
2017 Standout
Toll-like receptors as potential therapeutic targets for multiple diseases
2002
TLR4 links innate immunity and fatty acid–induced insulin resistance
2006 Standout
Long-term Erythromycin Therapy Is Associated with Decreased Chronic Obstructive Pulmonary Disease Exacerbations
2008
Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease
2003
Human interferon lambda-1 (IFN-λ1/IL-29) modulates the Th1/Th2 response
2007
The development of allergic inflammation
2008 StandoutNature
RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus
2015
Neutrophil extracellular traps in immunity and disease
2017 Standout
Interferon‐λ1 (interleukin‐29) preferentially down‐regulates interleukin‐13 over other T helper type 2 cytokine responses in vitro
2008
Interferon-λ Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family
2009
Defensins in innate antiviral immunity
2006
Interpretative strategies for lung function tests
2005 Standout
Periodontitis: from microbial immune subversion to systemic inflammation
2014 Standout
The immunology of asthma
2014
The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila
2008 StandoutNobel
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Updated Clinical Classification of Pulmonary Hypertension
2013 Standout
Genetic Variation of the IL-28B Promoter Affecting Gene Expression
2011
Type III IFN‐λ mRNA expression in sputum of adult and school‐aged asthmatics
2008
Interferon lambdas: the next cytokine storm
2011
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
Deficient antiviral immune responses in childhood: Distinct roles of atopy and asthma
2012
IFN-λs
2011
Asthma phenotypes: the evolution from clinical to molecular approaches
2012 Standout
IL-28A, IL-28B, and IL-29: Promising cytokines with type I interferon-like properties
2010
IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo
2008
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
2020 Standout
Remodeling in Asthma
2009
Exacerbations of chronic obstructive pulmonary disease
2007
Mechanisms and Experimental Models of Chronic Obstructive Pulmonary Disease Exacerbations
2005
Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention
2007 Standout
Airway Mucus Function and Dysfunction
2010 Standout
Protective and pathogenic functions of macrophage subsets
2011 Standout
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
2017
Treatment strategies for allergy and asthma
2008
Salmeterol and Fluticasone Propionate and Survival in Chronic Obstructive Pulmonary Disease
2007 Standout
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Guidelines for the management of adult lower respiratory tract infections
2005
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
2002 Standout
Global burden of COPD: risk factors, prevalence, and future trends
2007 Standout
Clinical Practice Guidelines and Quality of Care for Older Patients With Multiple Comorbid Diseases
2005 Standout
Chronic obstructive pulmonary disease: molecular and cellularmechanisms
2003
Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease
2008
Control of adaptive immunity by the innate immune system
2015 Standout
COPD exacerbations: definitions and classifications
2003
Strain-specific Immune Response to Haemophilus influenzae in Chronic Obstructive Pulmonary Disease
2003
The Effect of Inhaled IFN-β on Worsening of Asthma Symptoms Caused by Viral Infections. A Randomized Trial
2014
Bronchiolitis to Asthma
2006
The Superiority of IFN-λ as a Therapeutic Candidate to Control Acute Influenza Viral Lung Infection
2016
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Early Therapy Improves Outcomes of Exacerbations of Chronic Obstructive Pulmonary Disease
2004
Biopsy Neutrophilia, Neutrophil Chemokine and Receptor Gene Expression in Severe Exacerbations of Chronic Obstructive Pulmonary Disease
2003
Functional Polymorphism in the Suppressor of Cytokine Signaling 1 Gene Associated with Adult Asthma
2006
Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology
2010
The ABCs of Rhinoviruses, Wheezing, and Asthma
2010
The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections
2014 StandoutNobel
Antibiotics for exacerbations of chronic obstructive pulmonary disease
2012
Respiratory Viruses Other than Influenza Virus: Impact and Therapeutic Advances
2008
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo
2010
Lung damage and airway remodelling in severe asthma
2011
IFN-λ1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells
2009
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
IL-4 enhances IFN-λ1 (IL-29) production by plasmacytoid DCs via monocyte secretion of IL-1Ra
2010
Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease
2006
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Mouse CD8α+ DCs and human BDCA3+ DCs are major producers of IFN-λ in response to poly IC
2010
Physical Activity and Public Health in Older Adults
2007 Standout
Rhinovirus Infection of Allergen-Sensitized and -Challenged Mice Induces Eotaxin Release from Functionally Polarized Macrophages
2010
Alpha/Beta Interferon Receptor Signaling Amplifies Early Proinflammatory Cytokine Production in the Lung during Respiratory Syncytial Virus Infection
2014
Works of Simon Message being referenced
Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production
2008
Defining critical roles for NF‐κB p65 and type I interferon in innate immunity to rhinovirus
2012
Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma
2014
Viruses in asthma
2002
Rhinovirus induces MUC5AC in a human infection model andin vitroviaNF-κB and EGFR pathways
2010
Role of deficient type III interferon-λ production in asthma exacerbations
2006
Co-ordinated Role of TLR3, RIG-I and MDA5 in the Innate Response to Rhinovirus in Bronchial Epithelium
2010
An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study
2006
Increased aeroallergen‐specific interleukin‐4‐producing T cells in asthmatic adults
2002
Respiratory Viruses, Symptoms, and Inflammatory Markers in Acute Exacerbations and Stable Chronic Obstructive Pulmonary Disease
2001
Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production
2006
Host defense function of the airway epithelium in health and disease: clinical background
2003