Citation Impact
Citing Papers
Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry
2008 Science
Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
2012 Standout
Development and Implementation of a Miniaturized High-Throughput Time-Resolved Fluorescence Energy Transfer Assay to Identify Small Molecule Inhibitors of Polo-Like Kinase 1
2007
Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review
2023 Standout
The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change
2008
Discovery of Potent and Selective Covalent Inhibitors of JNK
2012
Pharmacoinformatics approach for the identification of Polo-like kinase-1 inhibitors from natural sources as anti-cancer agents
2018
Miniproteins as a Powerful Modality in Drug Development
2020
A view on drug resistance in cancer
2019 StandoutNature
The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
2013 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
2013 Standout
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Thymoquinone: Potential cure for inflammatory disorders and cancer
2011 Standout
Challenges and opportunities for non-antibody scaffold drugs
2015
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
2011
Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1
2008
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases
2008
Targeting cancer with small molecule kinase inhibitors
2008 Standout
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Memory of viral infections by CRISPR-Cas adaptive immune systems: Acquisition of new information
2012 StandoutNobel
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes
2015 StandoutNobel
Using transcriptome sequencing to identify mechanisms of drug action and resistance
2012
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity
2013
Common pitfalls in preclinical cancer target validation
2017 StandoutNobel
In vitro-engineered non-antibody protein therapeutics
2017
Targeting Echinococcus multilocularis Stem Cells by Inhibition of the Polo-Like Kinase EmPlk1
2014
Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System
2012 StandoutNobel
Polo and Aurora kinases — lessons derived from chemical biology
2008
De novo design of buttressed loops for sculpting protein functions
2024 StandoutNobel
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity
2015 StandoutNobel
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
2010 Standout
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
Anxiolytic Effects of Phosphodiesterase-2 Inhibitors Associated with Increased cGMP Signaling
2009
Multiple Conformations of Phosphodiesterase-5
2006
Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression
2021 StandoutNobel
Cell cycle kinases as therapeutic targets for cancer
2009
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity
2009
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
2016 StandoutNobel
Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct
2009
Echinococcosis: Advances in the 21st Century
2019 Standout
Assessing the performance of docking scoring function, FEP, MM-GBSA, and QM/MM-GBSA approaches on a series of PLK1 inhibitors
2017
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies
2019 StandoutNobel
Beyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis
2017
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Works of Simon Low being referenced
Research Article: Selectivity‐determining Residues in Plk1
2007
Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering
2014
Structure of the Catalytic Domain of Human Polo-like Kinase 1,
2007
Structural Determinants for Inhibitor Specificity and Selectivity in PDE2A Using the Wheat Germ in Vitro Translation System
2005