Standout Papers
Citation Impact
Citing Papers
neurotic , a novel maternal neurogenic gene, encodes an O -fucosyltransferase that is essential for Notch-Delta interactions
2003
A heterotrimeric death domain complex in Toll signaling
2002
A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice
2007 StandoutScienceNobel
An O -fucose site in the ligand binding domain inhibits Notch activation
2003
[35] Epitope tagging and protein surveillance
1991
An EGFR/Ebi/Sno Pathway Promotes Delta Expression by Inactivating Su(H)/SMRTER Repression during Inductive Notch Signaling
2002
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Lack of requirement for Presenilin1 in Notch1 signaling
1999
Down-regulation of Delta by proteolytic processing
2002
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
1998 StandoutNature
Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation
1997
The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters
1999
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins
1994
The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain
1996
The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.
1995
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
In Vivo Regulation of the IκB Homologue cactus during the Immune Response of Drosophila
1998 StandoutNobel
Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila
1996
A dual function of the Notch gene in Drosophila sensillum development
1990
The suppressor of hairless protein participates in notch receptor signaling
1994
Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation
1999
Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane
1997
LIN-12/Notch signaling: lessons from worms and flies
1998
Notch and neurogenesis
1998
Nuclear Notch1 signaling and the regulation of dendritic development
2000
Genetic and Molecular Bases of Neurogenesis in Drosophila Melanogaster
1991
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
1991
Roles of the ankyrin repeats and C-terminal region of the mouse Notch1 intracellular region
1998 StandoutNobel
Cell autonomy of lin-12 function in a cell fate decision in C. elegans
1989
An Activated Form of Notch Influences the Choice between CD4 and CD8 T Cell Lineages
1996
An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
1993 Nature
The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions
1990
Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells
1992
IκB-β regulates the persistent response in a biphasic activation of NF-κB
1995
Neurogenic genes and vertebrate neurogenesis
1996
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Mutations in erupted, the Drosophila Ortholog of Mammalian Tumor Susceptibility Gene 101, Elicit Non-Cell-Autonomous Overgrowth
2005
Notch/LIN-12 signaling: transduction by regulated protein slicing
1998
Oncogenic Forms of NOTCH1 Lacking Either the Primary Binding Site for RBP-Jκ or Nuclear Localization Sequences Retain the Ability to Associate with RBP-Jκ and Activate Transcription
1997
Notch Receptors, Partners and Regulators: From Conserved Domains to Powerful Functions
1998
Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous
1995
The Notch Ligands, Jagged and Delta, Are Sequentially Processed by α-Secretase and Presenilin/γ-Secretase and Release Signaling Fragments
2003
Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel
1994 StandoutNatureNobel
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
1998 StandoutNatureNobel
The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch
1988 Nature
Cell Surface Presenilin-1 Participates in the γ-Secretase-like Proteolysis of Notch
1999
Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless
2005
Drosophila larval neuromuscular junction: Molecular components and mechanisms underlying synaptic plasticity
2000
Control of Daughter Cell Fates during Asymmetric Division: Interaction of Numb and Notch
1996
The dorsal protein enhances the biosynthesis and stability of theDrosophilaIkB homologue cactus
1995
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene
1991 StandoutNature
Kuz and TACE can activate Notch independent of ligand
2008
Early ventral expression of the Drosophila neurogenic locus mastermind
1991
Notch Signaling – Constantly on the Move
2007
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila
1990
Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila
1991 StandoutNobel
Genes required for specifying cell fates in Drosophila embryonic sensory nervous system
1990
A role for the Drosophila neurogenic genes in mesoderm differentiation
1991 StandoutNobel
A common enzyme connects Notch signaling and Alzheimer's disease
2000
The Ins and Outs of Notch Signaling
1997
A Novel Proteolytic Cleavage Involved in Notch Signaling
2000 Standout
Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor
1991
Presenilin is required for activity and nuclear access of Notch in Drosophila
1999 Nature
Positive and negative signals between interacting cells for establishing neural fate
1998
Molecular characterization of the Notch homologue from the Australian sheep blowfly, Lucilia cuprina
1998
The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo
1994
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
1993 StandoutNatureNobel
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF
1999
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila
1996 Nobel
The Conserved C2 Domain Protein Lethal (2) Giant Discs Regulates Protein Trafficking in Drosophila
2006
Requirement for Dynamin during Notch Signaling inDrosophilaNeurogenesis
1997
Microfibrillar Proteins MAGP-1 and MAGP-2 Induce Notch1 Extracellular Domain Dissociation and Receptor Activation
2006
Structural basis for autoinhibition of Notch
2007
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
Notchic-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation
2000
Functional Interaction between the Mouse Notch1 Intracellular Region and Histone Acetyltransferases PCAF and GCN5
2000 StandoutNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
Indirect evidence for Delta-dependent intracellular processing of Notch in Drosophila embryos
1998
Drosophila innate immunity: an evolutionary perspective
2002 StandoutNobel
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1
2000 Nature
The immune response of Drosophila
2003 StandoutNatureNobel
Requirements for Presenilin-Dependent Cleavage of Notch and Other Transmembrane Proteins
2000
Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans
1990 Nature
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Lateral inhibition during vulval induction in Caenorhabditis elegans
1988 Nature
Induction and regulation of antimicrobial peptides in Drosophila
1999
The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats
1987
Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor
1993
Intrinsic activity of the lin-12 and Notch intracellular domains in vivo
1993
OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development
2008
Zinc Stoichiometry of Yeast RNA Polymerase II and Characterization of Mutations in the Zinc-binding Domain of the Largest Subunit
2000
glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins
1989
A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit
1988
γ-Secretase-mediated proteolysis in cell-surface-receptor signalling
2002
Structure/function studies of lin-12/Notch proteins
1994
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
The many facets of Notch ligands
2008
A light-entrainment mechanism for the Drosophila circadian clock
1996 StandoutNatureNobel
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
The choice of cell fate in the epidermis of Drosophila
1991
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers
2007
Two groups of interrelated genes regulate early neurogenesis in Drosophila melanogaster
1988
The Notch amino terminus regulates protein levels and Delta-induced clustering of Drosophila Notch receptors
2004
Glycosylation regulates Notch signalling
2003
Ectodomain Shedding and Intramembrane Cleavage of Mammalian Notch Proteins Are Not Regulated through Oligomerization
2004
λ ZAP: a bacteriophage λ expression vector within vivoexcision properties
1988
Dif, a dorsal-related gene that mediates an immune response in Drosophila
1993
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
1992 StandoutNobel
Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins
1990 Nature
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1998 Nature
Human deltex is a conserved regulator of Notch signalling
1998
The Notch Locus and the Cell Biology of Neuroblast Segregation
1991
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts
2002
The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium
1994
Kuzbanian Controls Proteolytic Processing of Notch and Mediates Lateral Inhibition during Drosophila and Vertebrate Neurogenesis
1997
Notch is required for wingless signaling in the epidermis of Drosophila
1994
Correlating Notch Signaling with Thymocyte Maturation
1998
Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations
1990
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
The role of cell-cell interaction in the development of the drosophila visual system
1990
Involvement of Notch-1 in mammalian retinal neurogenesis: association of Notch-1 activity with both immature and terminally differentiated cells
1995
Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster
1987
Dorsal-ventral polarity in the Drosophila embryo
1993
The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
1994 Standout
Regulated nuclear import of Rel proteins in the Drosophila immune response
1998 Nature
pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo
1993
Function and Activation of NF-kappaB in the Immune System
1994 Standout
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants
1999 Nature
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development
1996
Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling
2008
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
1996 StandoutNature
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)
1995 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo.
1993
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Notch Ligands Are Substrates for ProteinO-Fucosyltransferase-1 and Fringe
2002
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
The Notch pathway: democracy and aristocracy in the selection of cell fate
1996
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε
1998
Cell-cell interactions that specify certain cell fates in C. elegans development
1989
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
Alterations in Notch signaling in neoplastic lesions of the human cervix.
1995
Inducible Nuclear Expression of Newly Synthesized IκBα Negatively Regulates DNA-Binding and Transcriptional Activities of NF-κB
1995
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Cactus protein degradation mediates Drosophila dorsal-ventral signaling.
1995
lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans
1994
Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor.
1996
Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development
1992
Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.
1995
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
1996
Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation
2001
Specificity of Rel-Inhibitor Interactions in Drosophila Embryos
1995
Transcriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila
1997
Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling
2003
Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.
1996
Nuclear Access and Action of Notch In Vivo
1998
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage.
1996
Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila
1998
Notch is required for successive cell decisions in the developing Drosophila retina.
1989
Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats
1985
The adhesion force of Notch with Delta and the rate of Notch signaling
2004
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.
1993
Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region
1987 StandoutNatureNobel
SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling
1997
Xotch , the Xenopus Homolog of Drosophila Notch
1990 Science
Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling
1996
Insertional Mutagenesis of the Drosophila Genome with Single P Elements
1988 Science
Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster.
1989
Leukemia-Associated Mutations within the NOTCH1 Heterodimerization Domain Fall into at Least Two Distinct Mechanistic Classes
2006
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
2000
The dorsal-related immunity factor, Dif, is a sequence-specific trans-activator of Drosophila Cecropin gene expression.
1995
Suppressor of Hairless, the Drosophila homologue of RBP-J.KAPPA., transactivates the neurogenic gene E(spl)m8.
1995 StandoutNobel
Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila
1995
The Notch locus of Drosophila is required in epidermal cells for epidermal development
1990
T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells.
1996
A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis
1998
Influence of gamma subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes.
1992 StandoutNobel
EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes.
1987
A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway
1996
The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis.
1990
The molecular logic of Notch signaling – a structural and biochemical perspective
2008
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
1996 Nobel
Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila.
1990
Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function.
1991
The notch gene product is a glycoprotein expressed on the cell surface of both epidermal and neuronal precursor cells during Drosophila development.
1989
Neoplastic Transformation by Truncated Alleles of Human NOTCH1/TAN1 and NOTCH2
1997 Nobel
Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis.
1996
Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway
1994
The pattern of transcription of the neurogenic gene Delta of Drosophila melanogaster
1990
A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1
2000
Investigating the Genetic Circuitry of Mastermind in Drosophila, a Notch Signal Effector
2007
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
1995
The Notch ligand Jagged1 is required for inner ear sensory development
2001
Lateral inhibition mediated by the Drosophila neurogenic gene delta is enhanced by proneural proteins.
1994
Genetic Interactions in Early Neurogenesis of Drosophila melanogaster
1985
The roles of receptor and ligand endocytosis in regulating Notch signaling
2005
Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors
2000
Role of Glycosylation in Development
2004
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and γ-secretase
2003
IRAK: A Kinase Associated with the Interleukin-1 Receptor
1996 Science
DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur
2007
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
A homolog of Drosophila Notch expressed during mammalian development
1991
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.
1995 StandoutNobel
The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder
2008
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis
1997
The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein.
1987
Novel Regulators of Bone Formation: Molecular Clones and Activities
1988 StandoutScience
Effect of Mutations in a Zinc-Binding Domain of Yeast RNA Polymerase C (III) on Enzyme Function and Subunit Association
1992
Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila
1990
Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements
1997
Evidence for Physical and Functional Association Between EMB-5 and LIN-12 in Caenorhabditis elegans
1996 Science
Notch Signaling
1995 Science
Truncated Mammalian Notch1 Activates CBF1/RBPJk-Repressed Genes by a Mechanism Resembling That of Epstein-Barr Virus EBNA2
1996
The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
2000
Autoregulation of I kappa B alpha activity.
1994
RBP-L, a Transcription Factor Related to RBP-Jκ
1997 StandoutNobel
Notch Inhibition of E47 Supports the Existence of a Novel Signaling Pathway
1998
Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element.
1996
Isolation, Characterization, and Expression in Escherichia coli of the DNA Polymerase Gene from Thermus aquaticus
1989
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Notch2: a second mammalian Notch gene
1992
Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal.
1993
The Notch1 receptor is cleaved constitutively by a furin-like convertase
1998
Disulfide cross-linking in crude embryonic lysates reveals three complexes of the Drosophila morphogen dorsal and its inhibitor cactus.
1994 StandoutNobel
Cell proliferation control by Notch signaling in Drosophila development
1998
An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells
1994 StandoutNobel
Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin
1992 StandoutScienceNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 Standout
The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD
1994
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates
1987
Identification and localization of a sea urchin Notch homologue: insights into vegetal plate regionalization and Notch receptor regulation
1997
THE LIN-12/Notch SIGNALING PATHWAY AND ITS REGULATION
1997
Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.
1996
The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila
1988
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
1994 StandoutNatureNobel
Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains
1989 Science
The molecular genetics of Enhancer of split, a gene required for embryonic neural development in Drosophila.
1988
Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates.
1988
Cellular interactions during early neurogenesis of Drosophila melanogaster
1988
Dominant-negative mutation in the β2 and β6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage
1999
SKIP, a CBF1-Associated Protein, Interacts with the Ankyrin Repeat Domain of NotchIC To Facilitate NotchIC Function
2000
The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers.
1990
The function of the neurogenic genes during epithelial development in the Drosophila embryo
1992
Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2
2000
Positional Cloning and Sequence Analysis of the Drosophila Clock Gene, timeless
1995 Science
Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.
1988
Serrate expression can functionally replace Delta activity during neuroblast segregation in the Drosophila embryo
1995
Works of Simon Kidd being referenced
Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus
1987
Ligand-induced cleavage and regulation of nuclear entry of Notch in Drosophila melanogaster embryos
1998
Furin cleavage is not a requirement for Drosophila Notch function
2002
Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins
1992
kuzbanian-mediated cleavage of Drosophila Notch
2002
Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors.
1986 StandoutNobel
Sequence of the Notch Locus of Drosophila melanogaster: Relationship of the Encoded Protein to Mammalian Clotting and Growth Factors
1986
Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.
1993
An improved filamentous helper phage for generating single-stranded plasmid DNA
1986
Structure and distribution of the Notch protein in developing Drosophila.
1989
The Notch locus of Drosophila melanogaster
1983
Transposon-dependent mutant phenotypes at the Notch locus of Drosophila
1986 Nature
Restriction of P-element insertions at the Notch locus of Drosophila melanogaster.
1987