Standout Papers
Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
2020 StandoutNobel
The Isopeptidase USP2a Protects Human Prostate Cancer from Apoptosis
2006
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Frealign
2016
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase
2008 Nature
A structural view on the mechanism of the ribosome-catalyzed peptide bond formation
2009 StandoutNobel
Ribosome Function: Governing the Fate of a Nascent Polypeptide
2004
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Structure of the E. coli signal recognition particle bound to a translating ribosome
2006 Nature
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
2007
Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
2012 Nature
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Molecular Mechanism of Drug-Dependent Ribosome Stalling
2008
Membrane-protein topology
2006
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
Elongation Arrest by SecM via a Cascade of Ribosomal RNA Rearrangements
2006 StandoutNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Three-Dimensional Structures of Translating Ribosomes by Cryo-EM
2004
Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments
2008
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
The role of distant mutations and allosteric regulation on LovD active site dynamics
2014
Protein Translocation Is Mediated by Oligomers of the SecY Complex with One SecY Copy Forming the Channel
2007
Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage
2015
The Geometry of the Ribosomal Polypeptide Exit Tunnel
2006 StandoutNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Cryo-EM structure of the ribosome–SecYE complex in the membrane environment
2011
A structural understanding of the dynamic ribosome machine
2008 StandoutNobel
Translation Arrest Requires Two-Way Communication between a Nascent Polypeptide and the Ribosome
2006
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Super-resolution biomolecular crystallography with low-resolution data
2010 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
A model for co‐translational translocation: Ribosome‐regulated nascent polypeptide translocation at the protein‐conducting channel
2006 StandoutNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics
2008 StandoutNobel
Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction
2012
Structure of the Mammalian 80S Ribosome at 8.7 Å Resolution
2008
Rationally engineering natural protein assemblies in nanobiotechnology
2011
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
The Lateral Gate of SecYEG Opens during Protein Translocation
2009
Mutational Analysis of the Ribosome
2007
Real-space refinement in PHENIX for cryo-EM and crystallography
2018 Standout
Principles of protein folding, misfolding and aggregation
2004
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
Molecular Dynamics Studies of the Archaeal Translocon
2006
Combining Efficient Conformational Sampling with a Deformable Elastic Network Model Facilitates Structure Refinement at Low Resolution
2007 StandoutNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance, and Antibiotics Inactivation
2007 StandoutNobel
Clues from cell metabolism
2010 StandoutNatureNobel
How small-molecule inhibitors of dengue-virus infection interfere with viral membrane fusion
2018
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel
Structural characterization of mRNA-tRNA translocation intermediates
2012 StandoutNobel
pH Dependence of Zika Membrane Fusion Kinetics Reveals an Off-Pathway State
2018
Size, Motion, and Function of the SecY Translocon Revealed by Molecular Dynamics Simulations with Virtual Probes
2006
The transition state for formation of the peptide bond in the ribosome
2006 StandoutNobel
Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
2009 StandoutNobel
Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
2018
Probing the SecYEG translocation pore size with preproteins conjugated with sizable rigid spherical molecules
2011 StandoutNobel
Signal Recognition Particle Receptor Exposes the Ribosomal Translocon Binding Site
2006 Science
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Directed Evolution of a Protein Container
2011 Science
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Channeling by Proximity: The Catalytic Advantages of Active Site Colocalization Using Brownian Dynamics
2010
RIBOSOME DYNAMICS: Insights from Atomic Structure Modeling into Cryo-Electron Microscopy Maps
2006 StandoutNobel
Protein Translocation Across the Bacterial Cytoplasmic Membrane
2007
Multiple conformational switches in a GTPase complex control co-translational protein targeting
2009
A nascent polypeptide domain that can regulate translation elongation
2004
The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity
2014
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
2012 StandoutNobel
The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
2011 StandoutScienceNobel
Fatty Acid Synthase and Cancer: New Application of an Old Pathway
2006
Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome
2009 Science
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action
2005 StandoutNobel
Works of Simon Jenni being referenced
Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling
2007 Science
Architecture of a Fungal Fatty Acid Synthase at 5 A Resolution
2006 Science
The multienzyme architecture of eukaryotic fatty acid synthases
2008
The Structural Basis of Macrolide–Ribosome Binding Assessed Using Mutagenesis of 23S rRNA Positions 2058 and 2059
2004
The crystal structure of dynamin
2011 Nature
Structure of the E. coli protein-conducting channel bound to a translating ribosome
2005 StandoutNatureNobel
Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy
2015
CryoEM Structure of an Influenza Virus Receptor-Binding Site Antibody–Antigen Interface
2017
Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly
2016
The chemistry of protein synthesis and voyage through the ribosomal tunnel
2003
Mechanism of membrane fusion induced by vesicular stomatitis virus G protein
2016
Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution
2006 Science
Structural Basis for Substrate Delivery by Acyl Carrier Protein in the Yeast Fatty Acid Synthase
2007 Science