Standout Papers
Citation Impact
Citing Papers
Antibiotics: past, present and future
2019 Standout
The preparation of resin-bound nitroalkenes and some applications in high pressure promoted cycloadditions
2000
Reactions in Droplets in Microfluidic Channels
2006 Standout
A novel catalytic asymmetric route towards skipped dienes with a methyl-substituted central stereogenic carbon
2013 StandoutNobel
Natural products: A continuing source of novel drug leads
2013 Standout
Phloroglucinol compounds of natural origin
2006 Standout
Natural products: An evolving role in future drug discovery
2011 Standout
Asymmetric Disulfonimide‐Catalyzed Synthesis of δ‐Amino‐β‐Ketoester Derivatives by Vinylogous Mukaiyama–Mannich Reactions
2014 StandoutNobel
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
Total Synthesis of Discodermolide: Optimization of the Effective Synthetic Route
2008
Combinatorial carbohydrate chemistry
2002
Directed evolution: new parts and optimized function
2009 StandoutNobel
Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones
2012 Standout
Marine natural products
1990 Standout
Discodermolide analogues as the chemical component of combination bacteriolytic therapy
2005
Drug development from marine natural products
2008 Standout
Prevalence and hazardous impact of pharmaceutical and personal care products and antibiotics in environment: A review on emerging contaminants
2021 Standout
Glycopeptide Antibiotics
2004
Glycopeptides: Update on an old successful antibiotic class
2006
Identification of synthetic compounds active against VRE: the role of the lipidated aminoglucose and the structure of glycopeptide binding pocket
2005
Anticancer drugs from nature—natural products as a unique source of new microtubule-stabilizing agents
2007
The recent impact of solid-phase synthesis on medicinally relevant benzoannelated nitrogen heterocycles
2002
Recent developments in antibacterial drug discovery: microbe-derived natural products – from collection to the clinic
2006
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Remarkable Structural Similarities between Diverse Glycosyltransferases
2002
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
Microtubule-binding agents: a dynamic field of cancer therapeutics
2010 Standout
Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin
2008
Bioassay-Guided Evolution of Glycosylated Macrolide Antibiotics in Escherichia coli
2007
New aspects of natural products in drug discovery
2007
Natural compounds for cancer treatment and prevention
2009 Standout
A Two-Component regulatory system with opposite effects on glycopeptide antibiotic biosynthesis and resistance
2020
Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation
2011 Standout
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Natural products in drug discovery
2008 Standout
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products
2007
How antibiotics kill bacteria: from targets to networks
2010 Standout
Catalytic, asymmetric reactions of ketenes and ketene enolates
2009
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Formation of benzo[ghi]fluoranthenes by palladium catalyzed intramolecular coupling
2000
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Linkers and Cleavage Strategies in Solid-Phase Organic Synthesis and Combinatorial Chemistry
2000
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
2012 Standout
Solid-Phase Intramolecular N-Acyliminium Pictet−Spengler Reactions as Crossroads to Scaffold Diversity
2004 StandoutNobel
Chemistry of Polyvalent Iodine
2008 Standout
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
N‐Heterocyclic Carbene‐Catalyzed Cyclization of Unsaturated Acyl Chlorides and Ketones
2011
Total Synthesis of [Ψ[C(═NH)NH]Tpg4]Vancomycin and its (4-Chlorobiphenyl)methyl Derivative: Impact of Peripheral Modifications on Vancomycin Analogues Redesigned for Dual d -Ala-d -Ala and d -Ala-d -Lac Binding
2014
Bioactive compounds in seaweed: functional food applications and legislation
2011 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Transition metals in organic synthesis: Highlights for the year 2005
2007
Phosphine Organocatalysis
2018 Standout
Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential
2007 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Total Synthesis of (+)-Ambruticin S: Probing the Pharmacophoric Subunit
2010
Diels–Alder reactions on solid supports
2001
Cyclobutarenes and Related Compounds
2003
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Electrospray ionization–principles and practice
1990 StandoutNobel
Synthesis of new copper(I)-complexed rotaxanes via click chemistry
2008 StandoutNobel
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?
2015 Standout
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
Diversifying Vancomycin via Chemoenzymatic Strategies
2005
Prenylated benzophenones from Clusia sandiensis
1991
Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]‐Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE
2016 StandoutNobel
Total Syntheses and Initial Evaluation of [Ψ[C(═S)NH]Tpg4]vancomycin, [Ψ[C(═NH)NH]Tpg4]vancomycin, [Ψ[CH2NH]Tpg4]vancomycin, and Their (4-Chlorobiphenyl)methyl Derivatives: Synergistic Binding Pocket and Peripheral Modifications for the Glycopeptide Antibiotics
2015
Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes
2015 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Glycopeptide and Lipoglycopeptide Antibiotics
2005
Enzymatic Glycosylation of Vancomycin Aglycon: Completion of a Total Synthesis of Vancomycin and N- and C-Terminus Substituent Effects of the Aglycon Substrate
2014
Total Synthesis and Biological Evaluation of C16 Analogs of (−)-Dictyostatin
2007
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Microwave assisted organic synthesis—a review
2001 Standout
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
The Renaissance of Natural Products as Drug Candidates
2005 Science
Synthesis and biological evaluation of novel analogues of dictyostatin
2007
Glycosyltransferases: Structures, Functions, and Mechanisms
2007 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Multivalent Antibiotics via Metal Complexes: Potent Divalent Vancomycins against Vancomycin-Resistant Enterococci
2003
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Selenium-Based Solid-Phase Synthesis of Benzopyrans II: Applications to Combinatorial Synthesis of Medicinally Relevant Small Organic Molecules
2000
Curie point pyrolysis in direct combination with low voltage electron impact ionization mass spectrometry. New method for the analysis of nonvolatile organic materials
1973
Recent chemistry of benzocyclobutenes
2001
C-Terminally modified peptides via cleavage of the HMBA linker by O-, N- or S-nucleophiles
2016 StandoutNobel
Important Flavonoids and Their Role as a Therapeutic Agent
2020 Standout
Works of Simon J. Shaw being referenced
Investigating Carboxylic Acid Analogues of Ambruticin through Semi‐Synthesis
2006
Investigating Amine Derivatives of Ambruticin VS‐5 and VS‐4
2008
15-Amido Erythromycins: Synthesis and in Vitro Activity of a New Class of Macrolide Antibiotics
2005
A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions
2006
Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues
2004
The Structure Activity Relationship of Discodermolide Analogues
2008
Traceless Linkers for Solid-phase Synthesis. Homo- and Hetero-Diels-Alder Reactions of o-Quinodimethanes
1998
Structural requirements for VanA activity of vancomycin analogues
2002
A new route to benzo[ghi]fluoranthene
1969
Design, Synthesis, and Evaluation of Analogues of (+)-14-Normethyldiscodermolide
2004
Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry
2013
Design, Synthesis, and Evaluation of Carbamate-Substituted Analogues of (+)-Discodermolide
2004
Fragment Assembly: An Alternative Approach to Generating Complex Polyketides
2006
Butylboronate esters as derivatives for gas-chromatography-mass spectrometry of hop constituents
1968
Mass spectrometry of hop compounds—II: Mass spectra of related oxygen heterocyclic compounds
1970
Toward Understanding How the Lactone Moiety of Discodermolide Affects Activity
2005
Hybrid Glycopeptide Antibiotics
2001
antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
2019 Standout