Simon Hsu

Discovery of a regioselectivity switch in nitrating P450s guided by molecular dynamics simulations and Markov models

Dynamics and Hydration of the Active Sites of Mammalian Cytochromes P450 Probed by Molecular Dynamics Simulations

The Structural Biology of Toll-like Receptors

Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells

Adaptors in Toll-Like Receptor Signaling and their Potential as Therapeutic Targets

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

Mechanism of Intracellular cAMP Sensor Epac2 Activation

Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains

New amphiphiles for membrane protein structural biology

Structure–function relationships of immunostimulatory polysaccharides: A review

Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Toll-Like Receptor Signaling Pathways

Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

Vaccine innovations for emerging infectious diseases—a symposium report

Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes

Sensing of microbial molecular patterns by Toll‐like receptors

Pivotal Role of Water in Terminating Enzymatic Function: A Density Functional Theory Study of the Mechanism-Based Inactivation of Cytochromes P450

Molecular Mimicry in Innate Immunity

Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography

Structural Insights into Glucan Phosphatase Dynamics Using Amide Hydrogen−Deuterium Exchange Mass Spectrometry