Citation Impact
Citing Papers
The Yeast Synaptojanin-like Proteins Control the Cellular Distribution of Phosphatidylinositol (4,5)-Bisphosphate
2002
Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3
2010 Science
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy
2013
Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways
2013 StandoutScience
Flavivirus Replication Complex Assembly Revealed by DNAJC14 Functional Mapping
2012 StandoutNobel
G-Protein Signaling Through Tubby Proteins
2001 Science
TOR Signaling in Growth and Metabolism
2006 Standout
Combined Vemurafenib and Cobimetinib in BRAF -Mutated Melanoma
2014 Standout
Imaging beyond the proteome
2012 StandoutNobel
β-Arrestin Scaffolding of Phosphatidylinositol 4-Phosphate 5-Kinase Iα Promotes Agonist-stimulated Sequestration of the β2-Adrenergic Receptor
2008 StandoutNobel
Molecular machinery for non-vesicular trafficking of ceramide
2003 Nature
Multiple Pools of Phosphatidylinositol 4-Phosphate Detected Using the Pleckstrin Homology Domain of Osh2p
2004
Oncogenic kinase signalling
2001 StandoutNature
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Signaling pathways controlling cell polarity and chemotaxis
2001
Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo
2002
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling
2005
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P
2004
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
TOR, a Central Controller of Cell Growth
2000 Standout
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Snares and munc18 in synaptic vesicle fusion
2002 StandoutNobel
PI3K in lymphocyte development, differentiation and activation
2003
Phosphoinositide 3-Kinase-mediated Activation of Cofilin Phosphatase Slingshot and Its Role for Insulin-induced Membrane Protrusion
2004 StandoutNobel
Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy
2002
Phosphatidylinositol 4-Phosphate Formation at ER Exit Sites Regulates ER Export
2006
Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
2002 StandoutNobel
PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans
2008 StandoutNobel
Live cell imaging of phosphoinositide dynamics with fluorescent protein domains
2006
Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication
2010
Survey of the year 2000 commercial optical biosensor literature
2001
Phosphoinositide Recognition Domains
2003
Membrane Fusion
2003 StandoutNobel
Mechanisms of thrombopoiesis
2005
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
External Lipid PI3P Mediates Entry of Eukaryotic Pathogen Effectors into Plant and Animal Host Cells
2010
Essential Ca2+-independent Role of the Group IVA Cytosolic Phospholipase A2 C2 Domain for Interfacial Activity
2003
Structural Basis for Discrimination of 3-Phosphoinositides by Pleckstrin Homology Domains
2000
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Expression Cloning of Protein Targets for 3-Phosphorylated Phosphoinositides
1999
Membrane lipids: where they are and how they behave
2008 Standout
Imaging and manipulating phosphoinositides in living cells
2007
Survey of the year 2003 commercial optical biosensor literature
2004
Membrane recognition by phospholipid-binding domains
2008
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
2006 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
2007 Standout
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components
2000
AKT/PKB Signaling: Navigating the Network
2017 Standout
Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages
2004 Standout
Imaging phosphoinositide dynamics using GFP‐tagged protein domains
2005
Structural Basis of 3-Phosphoinositide Recognition by Pleckstrin Homology Domains
2000
The PI3K Pathway in Human Disease
2017 Standout
Calcium Signaling
2007 Standout
Dynamics and diversity in autophagy mechanisms: lessons from yeast
2009 StandoutNobel
COPII and the regulation of protein sorting in mammals
2011 StandoutNobel
Spatial and Temporal Regulation of 3-Phosphoinositides by PI 3-Kinase and PTEN Mediates Chemotaxis
2002
Probing the Functional Equivalence of Otoferlin and Synaptotagmin 1 in Exocytosis
2011 StandoutNobel
Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes
2001
Mycobacterium tuberculosis Reprograms Waves of Phosphatidylinositol 3-Phosphate on Phagosomal Organelles
2004
Neutrophil recruitment and function in health and inflammation
2013 Standout
Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries
2014 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Dynamics of Phosphoinositides in Membrane Retrieval and Insertion
2003
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast
2006 StandoutNobel
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
2000
The Pleckstrin Homology Domain Proteins Slm1 and Slm2 Are Required for Actin Cytoskeleton Organization in Yeast and Bind Phosphatidylinositol-4,5-Bisphosphate and TORC2
2005
The PI3K‒PDK1 connection: more than just a road to PKB
2000
Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase
2002
Visualizing Cellular Phosphoinositide Pools with GFP-Fused Protein-Modules
2002
Phosphoinositide Regulation of the Actin Cytoskeleton
2003
Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins
2002 StandoutNobel
Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain
2004 StandoutNobel
Requirements for Transitional Endoplasmic Reticulum Site Structure and Function in Saccharomyces cerevisiae
2010
Membrane Recognition and Targeting by Lipid-Binding Domains
2003
Emerging evidence of signalling roles for PI(3,4)P2 in Class I and II PI3K-regulated pathways
2016
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
2010 StandoutNobel
Membrane-Protein Interactions in Cell Signaling and Membrane Trafficking
2005
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism
2003
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
2005 StandoutScience
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
2005
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
An Arabidopsis Homolog of YeastATG6/VPS30Is Essential for Pollen Germination
2007 StandoutNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Secretive Bacterial Pathogens and the Secretory Pathway
2012
Phospholipid-Based Signaling in Plants
2003
The PI3K–PDK1 connection: more than just a road to PKB
2000
Works of Simon DOWLER being referenced
Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase
2000
Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities
2000
Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity
2001
Protein Lipid Overlay Assay
2002
Protein Lipid Overlay Assay
2002
DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides
1999
Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity
2001
DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides
1999
Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities
2000