Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice
2004
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Inflammation and cancer
2002 StandoutNature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
p53: traffic cop at the crossroads of DNA repair and recombination
2005
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
Repair of damaged DNA by extracts from a xeroderma pigmentosum complementation group A revertant and expression of a protein absent in its parental cell line
1992
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Intermediate (6-4) photoproduct repair in Chinese hamster V79 mutant V-H1 correlates with intermediate levels of DNA incision and repair replication
1989
Genetic instabilities in human cancers
1998 StandoutNature
Telomeres and mechanisms of Robertsonian fusion
1998
Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cells
1992
Telomere states and cell fates
2000 StandoutNatureNobel
(6-4) Photoproducts and not cyclobutane pyrimidine dimers are the main UV-induced mutagenic lesions in Chinese hamster cells
1992
When Checkpoints Fail
1997 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Functional links between telomeres and proteins of the DNA-damage response
2004
COMMENTARY: p53 Tumor suppressor gene: from the basic research laboratory to the clinic—an abridged historical perspective
1996
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Telomeres and cancer: a tale with many endings
2003
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Cockayne syndrome – a primary defect in DNA repair, transcription, both or neither?
1996
Deoxyribonucleoside triphosphate levels: A critical factor in the maintenance of genetic stability
1994
Problems and paradigms: Fine tuning of DNA repair in transcribed genes: Mechanisms, prevalence and consequences
1993
Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation
1998
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
1992
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Repair of pyrimidine dimer ultraviolet light photoproducts by human cell extracts
1989
Rodent UV-Sensitive Mutant Cell Lines in Complementation Groups 6-10 Have Normal General Excision Repair Activity
1997
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
2001
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors
2018
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene
1991
Ku acts in a unique way at the mammalian telomere to prevent end joining
2000
The XPD complementation group
1992
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
1995
Where transcription meets repair
1994 StandoutNobel
Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics
1993
Somatic cell genetics approach to dissecting mammalian DNA repair
1989
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
The telomerase activator TA‐65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
2011
Telomeres and human disease: ageing, cancer and beyond
2005
The Hallmarks of Aging
2013 Standout
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Repair of telomeric DNA prior to replicative senescence
2000
Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers
1998
DNA repair
1993 StandoutNobel
Evidence of a differential organization of chromatin containing terminal or interstitial (TTAGGG)<sub>n</sub> repeats by in situ digestion with nucleases
1998
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang
2000
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Novel Chinese hamster ultraviolet-sensitive mutants for excision repair form complementation groups 9 and 10.
1991
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions.
1993 StandoutNobel
Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents.
1992
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Restoration of Nucleotide Excision Repair in a Helicase-Deficient XPD Mutant from Intragenic Suppression by a Trichothiodystrophy Mutation
2001 StandoutNobel
Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA.
1993
Regulation of Telomerase by Telomeric Proteins
2004
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients
1997 StandoutNobel
Substrate and Temperature Dependence of DNA Photolyase Repair Activity Examined with Ultrafast Spectroscopy
1997 StandoutNobel
Loss of DNA mismatch repair in acquired resistance to cisplatin.
1996
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
2005
Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells.
1994
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Cancer Cell Cycles
1996 StandoutScience
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Ku is associated with the telomere in mammals
1999 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.
1993
Telomere fusions caused by mutating the terminal region of telomeric DNA
2000 StandoutNobel
Telomeres and telomerase: more than the end of the line
1999
Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.
2003 StandoutNobel
Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia
2001 Nobel
Short Telomeres Induce a DNA Damage Response inSaccharomyces cerevisiae
2003 StandoutNobel
THE BIOLOGY OF THE (6–4) PHOTOPRODUCT
1989
Identification of the eleventh complementation group of UV-sensitive excision repair-defective rodent mutants.
1992
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b.
1994 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Abnormal Centrosome Amplification in the Absence of p53
1996 Science
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.
1994 StandoutNobel
ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.
1990
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
1992 StandoutNobel
Cockayne syndrome group B protein enhances elongation by RNA polymerase II
1997 StandoutNobel
Works of Simon Bouffler being referenced
Telomere length, chromatin structure and chromosome fusigenic potential
1997
The role of DNA repeats and associated secondary structures in genomic instability and neoplasia
1993
The involvement of telomeric sequences in chromosomal aberrations
1996
Cockayne's syndrome fibroblasts are characterized by hypersensitivity to deoxyguanosine and abnormal DNA precursor pool metabolism in response to deoxyguanosine or ultraviolet light
1992
Elongated Telomeres inscidMice
1999
Molecular mechanisms of alkylation sensitivity in Indian muntjac cell lines
1989
PU.1 downregulation in murine radiation-induced acute myeloid leukaemia (AML): from molecular mechanism to human AML
2015
Long but dysfunctional telomeres correlate with chromosomal radiosensitivity in a mouse AML cell line
2001
Mammalian cells share a common pathway for the relief of DNA replication arrest by O6-alkyl guanine, incorporated 6-thioguanine and UV photoproducts
1992
Evidence for Msh2 haploinsufficiency in mice revealed by MNU-induced sister-chromatid exchange analysis
2000
Murine radiation myeloid leukaemogenesis: Relationship between interstitial telomere‐like sequences and chromosome 2 fragile sites
1993
Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12
1999
Telomere length abnormalities in mammalian radiosensitive cells.
2001
Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice.
1995
Short Telomeres Result in Organismal Hypersensitivity to Ionizing Radiation in Mammals
2000
CHO mutant UV61 removes (6–4) photoproducts but not cyclobutane dimers
1989