Citation Impact
Citing Papers
NMR structure reveals intramolecular regulation mechanism for pheromone binding and release
2001 StandoutNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
2018 StandoutScience
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
A rapid phospholipase D assay using zirconium precipitation of anionic substrate phospholipids: application to N-acylethanolamine formation in vitro
2000
Functional architecture of an intracellular membrane t-SNARE
2000 StandoutNatureNobel
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Structural views of phosphoinositide-specific phospholipase C: signalling the way ahead
1996
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains
1996 Nature
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
The C2 domain calcium‐binding motif: Structural and functional diversity
1996
N‐acylphosphatidylethanolamine‐hydrolysing phospholipase D lacks the ability to transphosphatidylate
1999
A Primer on Vesicle Budding
1999 StandoutNobel
Oxytocin and Male Reproductive Function
1997
Necroptosis and its role in inflammation
2015 StandoutNature
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis
2006
Chromatin Modifications and Their Function
2007 Standout
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Phosphoinositide phosphatases in cell biology and disease
2010
Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors
1999 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Lessons from the Cancer Genome
2013
A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: Identification of duplicated repeats and potential active site residues
1996
Identification and Cloning of Centaurin-α
1996
Autophagy regulates lipid metabolism
2009 StandoutNature
Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from β-spectrin 1 1Edited by P. E. Wright
1997
Molecular Characterization of a Phospholipase D Generating Anandamide and Its Congeners
2004 Standout
Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export
2003
ARF proteins mediate insulin-dependent activation of phospholipase D
1997
Different Domains of Mammalian ADP-ribosylation Factor 1 Mediate Interaction with Selected Target Proteins
1997
The role of lipid signaling in constitutive membrane traffic
1997
Activation of phospholipase Cgamma by PI 3-kinase-induced PH domain-mediated membrane targeting
1998
Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
2005
The Small GTPase Rho: Cellular Functions and Signal Transduction
1996
Binding of Basic Peptides to Membranes Produces Lateral Domains Enriched in the Acidic Lipids Phosphatidylserine and Phosphatidylinositol 4,5-Bisphosphate: An Electrostatic Model and Experimental Results
1998
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Plasma membrane phosphoinositide organization by protein electrostatics
2005 Nature
The TRPM7 channel is inactivated by PIP2 hydrolysis
2002
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
TRP channels as cellular sensors
2003 StandoutNature
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity
1997
C2-domains, Structure and Function of a Universal Ca2+-binding Domain
1998 StandoutNobel
Localization of oxytocin receptors in the human and macaque monkey male reproductive tracts: evidence for a physiological role of oxytocin in the male
1998
Heterotrimeric G proteins
1996
Oxytocin and Oxytocin Receptor Expression in Reproductive Tissues of the Male Marmoset Monkey1
1997
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
2014
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
1997 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
C2 domain conformational changes in phospholipase C-δ1
1996
G Protein-coupled Receptors
1998 StandoutNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization
1997
Identification of a novel, Ca2+‐dependent phospholipase D with preference for phosphatidylserine and phosphatidylethanolamine in Saccharomyces cerevisiae
1996
Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation
1999
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking
1998
A duplicated catalytic motif in a new superfamily of phosphohydrolases and phospholipid synthases that includes poxvirus envelope proteins
1996
ADP-Ribosylation Factor 6 Regulates a Novel Plasma Membrane Recycling Pathway
1997
The Role of ADP-ribosylation Factor and Phospholipase D in Adaptor Recruitment
1997
Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology
2003 Science
Prospore Membrane Formation Defines a Developmentally Regulated Branch of the Secretory Pathway in Yeast
1998
β 2 -Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
1998 StandoutNobel
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes
1998 StandoutNobel
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
2000 StandoutNobel
Signal-dependent membrane targeting by pleckstrin homology (PH) domains
2000
RANTES Activation of Phospholipase D in Jurkat T Cells: Requirement of GTP-Binding Proteins ARF and RhoA
1998
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles
1998 StandoutNobel
PLD1 and ERK2 regulate cytosolic lipid droplet formation
2006
Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase.
1996
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
Functional association between Arf and RalA in active phospholipase D complex
1998
Localization of a high-affinity inositol 1,4,5-trisphosphate/inositol 1,4,5,6-tetrakisphosphate binding domain to the pleckstrin homology module of a new 130 kDa protein: characterization of the determinants of structural specificity
1996
Surface structure of the COPII-coated vesicle
2001 StandoutNobel
Phospholipase D: molecular and cell biology of a novel gene family
2000
1997 StandoutNobel
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Global Analysis of Protein Activities Using Proteome Chips
2001 StandoutScience
Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network
1997
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
NMR structure of the calreticulin P-domain
2001 StandoutNobel
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
1998 StandoutScience
Works of Simon A. Rudge being referenced
PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity
2012
Inositol lipid-mediated signalling in response to endothelin and ATP in the mammalian testis
1995
The pleckstrin homology domain of phospholipase C-.delta.1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes
1995
Regulation and function of PLDs in yeast
1999
Human ADP-ribosylation Factor-activated Phosphatidylcholine-specific Phospholipase D Defines a New and Highly Conserved Gene Family
1995
Regulation and functions of phospholipase D
1997
Phospholipase D signaling is essential for meiosis.
1995
SPO14 Separation-of-Function Mutations Define Unique Roles for Phospholipase D in Secretion and Cellular Differentiation in Saccharomyces cerevisiae
2001
Vacuole Size Control: Regulation of PtdIns(3,5)P2Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P2-specific Phosphatase
2003
Regulation of phosphoinositide-3-kinase by G protein beta gamma subunits in a rat osteosarcoma cell line.
1995
Rat testicular myoid cells express vasopressin receptors: receptor structure, signal transduction, and developmental regulation.
1995
Relocalization of Phospholipase D Activity Mediates Membrane Formation During Meiosis
1998
Saccharomyces cerevisiae Sps1p Regulates Trafficking of Enzymes Required for Spore Wall Synthesis
2005
ADP-Ribosylation Factors Do Not Activate Yeast Phospholipase Ds but Are Required for Sporulation
1998
Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes
2002