Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
antiSMASH 6.0: improving cluster detection and comparison capabilities
2021 Standout
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins
2016
NF-κB in inflammation and renal diseases
2015
Signaling in Innate Immunity and Inflammation
2012
Physiological functions of the HECT family of ubiquitin ligases
2009
Ubiquitin-binding domains — from structures to functions
2009
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
2015
Myeloid-derived suppressor cells coming of age
2018 Standout
Autophagy in infection, inflammation and immunity
2013 Standout
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
2011 Nature
Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
2012
NF-κB signaling in inflammation
2017 Standout
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
2009
Ubiquitination in signaling to and activation of IKK
2012
Necroptosis and its role in inflammation
2015 StandoutNature
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Building ubiquitin chains: E2 enzymes at work
2009
A Ubiquitin Replacement Strategy in Human Cells Reveals Distinct Mechanisms of IKK Activation by TNFα and IL-1β
2009
c‐IAP1 and UbcH5 promote K11‐linked polyubiquitination of RIP1 in TNF signalling
2010
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Eaten alive: a history of macroautophagy
2010 Standout
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
2010
Activation and regulation of the inflammasomes
2013 Standout
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
DNA damage-induced nuclear factor-kappa B activation and its roles in cancer progression
2017
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
Type I interferons in infectious disease
2015 Standout
Crystal structure of inhibitor of κB kinase β
2011 Nature
NOD2 and inflammation: current insights
2018
The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO
2013
The NF-κB-independent functions of IKK subunits in immunity and cancer
2009
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction
2011
The structural biology of biosynthetic megaenzymes
2015
Autophagy: Renovation of Cells and Tissues
2011 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
NEMO specifically recognizes K63‐linked poly‐ubiquitin chains through a new bipartite ubiquitin‐binding domain
2009
Crystal structure of the NEMO ubiquitin‐binding domain in complex with Lys 63‐linked di‐ubiquitin
2009
IKK Regulation and Human Genetics
2010
Regulation of nuclear factor-κB in autoimmunity
2013
Auxiliary-assisted chemical ubiquitylation of NEMO and linear extension by HOIP
2019
Return to homeostasis: downregulation of NF-κB responses
2011
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation
2010
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Linear ubiquitination prevents inflammation and regulates immune signalling
2011 Nature
Regulation of tumour necrosis factor signalling: live or let die
2015
Linear ubiquitination in NF-κB signaling and inflammation: What we do understand and what we do not
2011
LUBAC, a novel ubiquitin ligase for linear ubiquitination, is crucial for inflammation and immune responses
2012
Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
2010
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex
2009
Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain
2009
LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB
2017
Crosstalk in NF-κB signaling pathways
2011 Standout
Ubiquitin signaling in immune responses
2016
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
2009
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
The Structure and Conformation of Lys63-Linked Tetraubiquitin
2009
Structural basis for specific recognition of Lys 63‐linked polyubiquitin chains by tandem UIMs of RAP80
2009
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Structural basis for specific recognition of Lys 63‐linked polyubiquitin chains by NZF domains of TAB2 and TAB3
2009
Fluorescence-Based Sensors to Monitor Localization and Functions of Linear and K63-Linked Ubiquitin Chains in Cells
2012
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
2011
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Control of adaptive immunity by the innate immune system
2015 Standout
Inflammasomes in health and disease
2012 StandoutNature
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
2017
Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
2016
Control of Life-or-Death Decisions by RIP1 Kinase
2013
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
2014
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
NEMO oligomerization and its ubiquitin-binding properties
2009
Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains
2009
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Cell Signaling in Space and Time: Where Proteins Come Together and When They’re Apart
2009 Science
The Effects of TLR Activation on T-Cell Development and Differentiation
2012
Ubiquitin and Parkinson's disease through the looking glass of genetics
2017
Novel cross-talk within the IKK family controls innate immunity
2011
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions
2012
B cell–intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice
2021 StandoutNobel
The Ubiquitin Code
2012 Standout
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Rapid access to Asp/Glu sidechain hydrazides as thioester precursors for peptide cyclization and glycosylation
2021 StandoutNobel
Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis
2018 StandoutNobel
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
2014
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Works of Simin Rahighi being referenced
Selectivity of the ubiquitin‐binding modules
2012
Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification
2014
Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
2009
Mechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex
2014