Citation Impact
Citing Papers
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter
2006 StandoutNobel
Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles
2001
Cancer statistics, 2020
2020 Standout
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
IRF-7 is the master regulator of type-I interferon-dependent immune responses
2005 StandoutNature
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
The therapeutic potential of interleukin-6 hyperagonists and antagonists
1997
CASK and Protein 4.1 Support F-actin Nucleation on Neurexins
2001 StandoutNobel
Regulation of Phosphorylation of Thr-308 of Akt, Cell Proliferation, and Survival by the B55α Regulatory Subunit Targeting of the Protein Phosphatase 2A Holoenzyme to Akt
2007
Combining immunotherapy and targeted therapies in cancer treatment
2012
Nuclear Phosphoinositides and Their Functions
2004
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
The mTOR pathway and its role in human genetic diseases
2008
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Familial nonmedullary thyroid carcinoma—clinical relevance and prognosis. A European multicenter study
2010
Phosphoinositides : key players in cell signalling, in time and space
2001
The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB
1999
The next generation of PDE4 inhibitors
2001
Cell surface adherence and endocytosis of protein transduction domains
2003
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
2002 StandoutNobel
Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processes
2009
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
2001 StandoutNobel
A Chromatin Insulator Determines the Nuclear Localization of DNA
2000
Relationships between Rap1b, Affinity Modulation of Integrin αIIbβ3, and the Actin Cytoskeleton
2002
N-Formyl Peptide Receptors Internalize but Do Not Recycle in the Absence of Arrestins
2003 StandoutNobel
Trafficking of the HIV Coreceptor CXCR4
1999
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Cell Cycle Regulation of Membrane Phospholipid Metabolism
1996
T cell life and death signalling via TNF-receptor family members
2000
Synergistic Inhibition of HIV-1 in Activated and Resting Peripheral Blood Mononuclear Cells, Monocyte-Derived Macrophages, and Selected Drug-Resistant Isolates With Nucleoside Analogues Combined With a Natural Product, Resveratrol
2000
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Phospholipids in the nucleus—metabolism and possible functions
1992
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Generation, Control, and Processing of Cellular Calcium Signals
2001
Programmed Cell Death as a Mechanism of CD4 and CD8 T Cell Deletion in AIDS: Molecular Control and Effect of Highly Active Anti‐retroviral Therapy
1999 StandoutNobel
Heterotrimeric G protein activation by G-protein-coupled receptors
2007
Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells
1992 Nature
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment
2009
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Cisplatin in cancer therapy: Molecular mechanisms of action
2014 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Identification of the key genes and microRNAs in adult acute myeloid leukemia with FLT3 mutation by bioinformatics analysis
2020
GIT Proteins, A Novel Family of Phosphatidylinositol 3,4,5-Trisphosphate-stimulated GTPase-activating Proteins for ARF6
2000 StandoutNobel
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
The TNF and TNF Receptor Superfamilies
2001 Standout
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
The Regulation of Apoptosis by Microbial Pathogens
1999
Integrins
2002 Standout
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120
1995 Nature
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
2002
PIKE
2000
The Long-Term Outcomes of the Second Generation of Familial Nonmedullary Thyroid Carcinoma Are More Aggressive than Sporadic Cases
2012
Prevalence, Clinicopathologic Features, and Somatic Genetic Mutation Profile in Familial Versus Sporadic Nonmedullary Thyroid Cancer
2010
In Patients with Thyroid Cancer of Follicular Cell Origin, a Family History of Nonmedullary Thyroid Cancer in One First-Degree Relative Is Associated with More Aggressive Disease
2011
T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons.
1995
Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy
2008
Transgenic Expression of Stromal Cell-Derived Factor-1/CXC Chemokine Ligand 12 Enhances Myeloid Progenitor Cell Survival/Antiapoptosis In Vitro in Response to Growth Factor Withdrawal and Enhances Myelopoiesis In Vivo
2003
Fluorine in medicinal chemistry
2007 Standout
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2
1999 StandoutScience
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Transforming Growth Factor β/Smad3 Signaling Regulates IRF-7 Function and Transcriptional Activation of the Beta Interferon Promoter
2004
Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy
2006 StandoutNobel
Expression and properties of two distinct classes of the phorbol ester receptor family, four conventional protein kinase C types, and a novel protein kinase C.
1990
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Intrinsic Human Immunodeficiency Virus Type 1 Resistance of Hematopoietic Stem Cells Despite Coreceptor Expression
1999
Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase
2002
Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
2008 Standout
Neither Human Immunodeficiency Virus-1 (HIV-1) nor HIV-2 Infects Most-Primitive Human Hematopoietic Stem Cells as Assessed in Long-Term Bone Marrow Cultures
1998
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Glucose-induced changes in protein kinase C and nitric oxide are prevented by vitamin E
2000
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Structure, Function, and Control of Phosphoinositide-Specific Phospholipase C
2000
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
2002 StandoutNobel
Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells.
1989
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans.
1991 StandoutNobel
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron
2012 StandoutNobel
Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State
2001 Standout
A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrix.
1992
Autophagy, a key mechanism of oncogenesis and resistance in leukemia
2016
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
1993 StandoutNobel
Viral Subversion of the Immune System
2000
Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1
1999
Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest
1997
Identification of intracellular receptor proteins for activated protein kinase C.
1991
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Induction of Apoptosis in Uninfected Lymphocytes by HIV-1 Tat Protein
1995 Science
A Role for Nuclear PTEN in Neuronal Differentiation
2000
The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis.
1995
Prospects for the Future
2002 StandoutScienceNobel
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Works of Silvano Capitani being referenced
Extracellular HIV-1 Tat Protein Up-Regulates the Expression of Surface CXC-Chemokine Receptor 4 in Resting CD4+ T Cells
1999
Extracellular Human Immunodeficiency Virus Type-1 Tat Protein Activates Phosphatidylinositol 3-Kinase in PC12 Neuronal Cells
1996
Nuclear Diacylglycerol Produced by Phosphoinositide-specific Phospholipase C Is Responsible for Nuclear Translocation of Protein Kinase C-α
1998
Targeting PI3K/AKT/mTOR network for treatment of leukemia
2015
Recombinant human immunodeficiency virus type‐1 (HIV‐1) Tat protein sequentially up‐regulates IL‐6 and TFG‐β1 mRNA expression and protein synthesis in peripheral blood monocytes
1994
Familial non-medullary thyroid carcinoma displays the features of clinical anticipation suggestive of a distinct biological entity
2008
Intranuclear Translocation of Phospholipase C β2 during HL-60 Myeloid Differentiation
1997
Nuclear lipids: New functions for old molecules?
2003
The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system
2002
Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia
2012
Extracellular HIV‐1 Tat protein activates phosphatidylinositol 3‐ and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells
1997
Inositol lipid cycle and autonomous nuclear signalling
1996
Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells
1999
Translocation of Akt/PKB to the nucleus of osteoblast‐like MC3T3‐E1 cells exposed to proliferative growth factors
2000
Nuclear translocation of protein kinase C‐α and ‐ζ isoforms in HL‐60 cells induced to differentiate along the granulocytic lineage by all‐trans retinoic acid
1996
Lipid phosphorylation in isolated rat liver nuclei Synthesis of polyphosphoinositides at subnuclear level
1989
Uptake and phosphorylation of phosphatidylinositol by rat liver nuclei. Role of phosphatidylinositol transfer protein
1990
Extracellular HIV-1 Tat Protein Induces a Rapid and Selective Activation of Protein Kinase C (PKC)-α, -ϵ, and -ζ Isoforms in PC12 Cells
1998
TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells
2004
Enhancement of TRAIL cytotoxicity by AG-490 in human ALL cells is characterized by downregulation of cIAP-1 and cIAP-2 through inhibition of Jak2/Stat3
2009
Nuclear polyphosphoinositides during cell growth and differentiation
1989
Threonine 308 phosphorylated form of akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin
2003
Phosphatidylinositol 3-Kinase in HL-60 Nuclei Is Bound to the Nuclear Matrix and Increases During Granulocytic Differentiation
1998
Changes of Nuclear PI-PLC γ1 During Rat Liver Regeneration
1997
Extracellular HIV-1 Tat protein differentially activates the JNK and ERK/MAPK pathways in CD4 T cells
1999
All‐trans retinoic acid shows multiple effects on the survival, proliferation and differentiation of human fetal CD34+ haemopoietic progenitor cells
1995
Morphological evidence of function-related localization of phospholipids in the cell nucleus
1992
Nuclear association of tyrosine‐phosphorylated Vav to phospholipase C‐γ1 and phosphoinositide 3‐kinase during granulocytic differentiation of HL‐60 cells
1998
Engagement of CD28 Modulates CXC Chemokine Receptor 4 Surface Expression in Both Resting and CD3-Stimulated CD4+ T Cells
2000
Nuclear phosphoinositide-specific phospholipase C, phosphatidylinositol 4,5-bisphosphate and protein kinase C during rat spermatogenesis.
1996
Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+T cell hyperactivation and HIV type 1 replication
2000
Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD4+ T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD95/CD95 Ligand Pathway
1999
Antiangiogenic Activity of the MDM2 Antagonist Nutlin-3
2006
Decrease in nuclear phospholipids associated with DNA replication
1993
Cisplatin-induced apoptosis in human promyelocytic leukemia cells
2006
Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD4+ T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD95/CD95 Ligand Pathway
1999
Nuclear translocation of phosphatidylinositol 3-kinase in rat pheochromocytoma PC 12 cells after treatment with nerve growth factor.
1994
Thrombopoietin Enhances the αIIbβ3-Dependent Adhesion of Megakaryocytic Cells to Fibrinogen or Fibronectin Through PI 3 Kinase
1997
The human immunodeficiency virus type-1 Tat protein upregulates Bcl-2 gene expression in Jurkat T-cell lines and primary peripheral blood mononuclear cells
1995
In vitro phosphorylation of lamin B by protein kinase C in friend erythroleukemia. Effect of chemically induced differentiation
1991
Progressive and Persistent Downregulation of Surface CXCR4 in CD4+ T Cells Infected With Human Herpesvirus 7
1998
Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4+ T cells
2001
Inhibition of purified CD34+ hematopoietic progenitor cells by human immunodeficiency virus 1 or gp120 mediated by endogenous transforming growth factor beta 1.
1996
Multiple biological responses activated by nuclear protein kinase C
1999
Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis.
1993
Lipid-DNA interactions. II. Phospholipids, cholesterol, glycerophosphorylcholine, sphingosine and fatty acids
1974
Stromal derived factor-1α (SDF-1α) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway
2001
In vitro exposure to human immunodeficiency virus type 1 induces apoptotic cell death of the factor-dependent TF-1 hematopoietic cell line
1994
Immunochemical characterization of protein kinase C in rat liver nuclei and subnuclear fractions
1987
Proliferating or Differentiating Stimuli Act on Different Lipid-dependent Signaling Pathways in Nuclei of Human Leukemia Cells
2002
Progressive and Persistent Downregulation of Surface CXCR4 in CD4+ T Cells Infected With Human Herpesvirus 7
1998
A subset of human CD34+ hematopoietic progenitors express low levels of CD4, the high-affinity receptor for human immunodeficiency virus-type 1
1994
Increase in nuclear phosphatidylinositol 3‐kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC‐ζ translocation to the nucleus of NGF‐treated PC12 cells
1999
Human herpesvirus 7 induces the down-regulation of CD4 antigen in lymphoid T cells without affecting p56lck levels.
1997
Stromal derived factor-1 alpha (SDF-1 alpha) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway.
2001