Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs
2022 StandoutNobel
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
2008 Standout
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review
2023 Standout
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
2023 Standout
Guidelines for the welfare and use of animals in cancer research
2010 Standout
Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo
2018 Standout
Inference and analysis of cell-cell communication using CellChat
2021 Standout
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Adults with genetic syndromes and cardiovascular abnormalities: clinical history and management
2008
Gastric emptying in Parkinson's disease
1996
Ras oncogenes: split personalities
2008
Gastrointestinal dysfunction in Parkinson's disease
2003 Standout
Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders
2007
Pathological roles of MAPK signaling pathways in human diseases
2010 Standout
Rheb Inhibits C-Raf Activity and B-Raf/C-Raf Heterodimerization
2006
Regulation of chromatin by histone modifications
2011 Standout
Single-Cell Profiling Identifies Aberrant STAT5 Activation in Myeloid Malignancies with Specific Clinical and Biologic Correlates
2008
RAS oncogenes: weaving a tumorigenic web
2011
A computationally engineered RAS rheostat reveals RAS–ERK signaling dynamics
2016 StandoutNobel
The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders
2008
Birth incidence and prevalence of tumor‐prone syndromes: Estimates from a UK family genetic register service
2010 Standout
A Fifth of the Protein World: Rossmann-like Proteins as an Evolutionarily Successful Structural unit
2020
Ras history
2010
Ras proteins: paradigms for compartmentalised and isoform-specific signalling
2007
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Noonan syndrome and related disorders: dysregulated RAS-mitogen activated protein kinase signal transduction
2006
Recurring HRAS mutation G12S in Dutch patients with Costello syndrome
2006
Research Perspectives in Inherited Lymphatic Disease
2008
Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by 18F-FDG-PET is associated with the KRAS mutation status and prognosis
2018 StandoutNobel
Mechanisms of drug combinations: interaction and network perspectives
2009 Standout
Genetic Basis for Congenital Heart Defects: Current Knowledge
2007
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Regulating the regulator: post-translational modification of RAS
2011
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
EMT: 2016
2016 Standout
Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development
2012
Maximizing mouse cancer models
2007
Hyperactive Ras in developmental disorders and cancer
2007
Reactive oxygen species in cancer
2010 Standout
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation
2009
Genotype differences in cognitive functioning in Noonan syndrome
2008
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
2008 Standout
Lymphedema beyond breast cancer
2010 Standout
Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1–like phenotype
2007
Computation of Conformational Coupling in Allosteric Proteins
2009 StandoutNobel
22q11.2 deletion syndrome
2015 Standout
ROS signalling in the biology of cancer
2017 Standout
Mining electronic health records: towards better research applications and clinical care
2012 Standout
Slaying RAS with a synthetic lethal weapon
2010 StandoutNobel
The cancer genome
2009 StandoutNature
Germline Missense Mutations Affecting KRAS Isoform B Are Associated with a Severe Noonan Syndrome Phenotype
2006
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
The MAPK pathway across different malignancies: A new perspective
2014 Standout
Oncogenic transformation and experimental models of human cancer
2007
Biochemical and Functional Characterization of Germ Line KRAS Mutations
2007
The Spectrum of Cardiac Anomalies in Noonan Syndrome as a Result of Mutations in the PTPN11 Gene
2007
2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy
2011 Standout
The preparation of magnetic nanoparticles for applications in biomedicine
2003 Standout
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
2008 Standout
Repurposing approved drugs on the pathway to novel therapies
2019
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
A Comprehensive Survey of Ras Mutations in Cancer
2012 Standout
Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation
2012
Recurrence of Congenital Heart Defects in Families
2009
Continuous inertial focusing, ordering, and separation of particles in microchannels
2007 Standout
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Isoform-Specific Ras Functions in Development and Cancer
2009
Field-Flow Fractionation: Analysis of Macromolecular, Colloidal, and Particulate Materials
1993 StandoutScience
Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management
2012 Standout
Works of Silke Böll being referenced
Germline KRAS mutations cause Noonan syndrome
2006
STRUCTURE AND EXPRESSION OF HUMAN ALPHA-INTERFERON GENES
1982