Citation Impact
Citing Papers
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System
1993
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
1998 StandoutNature
Functional diversity of helper T lymphocytes
1996 StandoutNature
Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor
1988 StandoutNobel
The Influence of Chromosomal Location on the Expression of Two Transgenes in Mice
1999 StandoutNobel
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Mechanism and Regulation of Immunoglobulin Isotype Switching
1993
Strictly Target Cell-dependent Activation of T Cells by Bispecific Single-chain Antibody Constructs of the BiTE Class
2007
Lymph nodes and Peyer's patches of IL-6 transgenic BALB/c mice harbor T(12;15) translocated plasma cells that contain illegitimate exchanges between the immunoglobulin heavy-chain μ locus and c-myc
2000
Induction of apoptosis in fibroblasts by c-myc protein
1992 Standout
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Identification of 3α-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation
1995
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
2000 StandoutNobel
CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis
2006
Developmental and Molecular Regulation of Immunoglobulin Class Switch Recombination
1996
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
1995 StandoutNatureNobel
Circular DNA is excised by immunoglobulin class switch recombination
1990 StandoutNobel
A class switch control region at the 3′ end of the immunoglobulin heavy chain locus
1994
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
Immunoglobulin Class Switching: Molecular and Cellular Analysis
1990
A zonal organization of odorant receptor gene expression in the olfactory epithelium
1993 StandoutNobel
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus
1998
DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally
1990
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Excessive bone resorption in human plasmacytomas: direct induction by tumour cells in vivo
1995
Modulation of EZH2 expression in T cells improves efficacy of anti–CTLA-4 therapy
2018 StandoutNobel
Clonal selection and learning in the antibody system
1996 StandoutNature
INTERACTION OF TUMOR AND HOST CELLS WITH ADHESION AND EXTRACELLULAR MATRIX MOLECULES IN THE DEVELOPMENT OF MULTIPLE MYELOMA
1997
Redundancy of information in enhancers as a principle of mammalian transcription control
1988
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Mechanisms of Bone Metastasis
2004 Standout
Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells
2004
Control of c-myc Regulation in Normal and Neoplastic Cells
1991
Bispecific antibodies: a mechanistic review of the pipeline
2019
Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells
1999 StandoutNobel
Clonal diversification of primary BALB/c plasmacytomas harboring T(12;15) chromosomal translocations
2000
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
How eukaryotic transcriptional activators work
1988 StandoutNature
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching
1988
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Characterization of immunoglobulin enhancer deletions in murine plasmacytomas.
1985
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
GERM-LINE TRANSFORMATION OF MICE
1986
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
Evolutionary and Somatic Selection of the Antibody Repertoire in the Mouse
1987 Science
Activation Of Cellular Oncogenes in Hemopoietic Cells by Chromosome Translocation
1986
Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
1989 StandoutNobel
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Bispecific Antibodies as Novel Bioconjugates
1998
Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.
1989
Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements
1985
A dominant interfering Myb mutant causes apoptosis in T cells.
1996
Structure and expression of germ line immunoglobulin gamma 2b transcripts.
1988
Directed Ig class switch recombination in activated murine B cells.
1987
High-frequency germ-line transmission of plasmid DNA sequences injected into fertilized zebrafish eggs.
1991 StandoutNobel
Enhancers and eukaryotic gene transcription
1985
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.
1989 StandoutNobel
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
1986 StandoutNobel
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
1986 Standout
Regulation of Inducible and Tissue-Specific Gene Expression
1987 Science
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction
1992 StandoutScience
Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells
1991 StandoutNobel
Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men
2006
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
The chromosomal distribution of mouse odorant receptor genes.
1996 StandoutNobel
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
1996 StandoutNobel
Development of the Primary Antibody Repertoire
1987 Science
Transcription cell type specificity is conferred by an immunoglobulin VH gene promoter that includes a functional consensus sequence
1985
Level of β-Adrenergic Receptor Kinase 1 Inhibition Determines Degree of Cardiac Dysfunction After Chronic Pressure Overload–Induced Heart Failure
2005 StandoutNobel
Formation of stable transcription complexes as assayed by analysis of individual templates.
1988
Activation of the c-myc oncogene by the immunoglobulin heavy-chain gene enhancer after multiple switch region-mediated chromosome rearrangements in a murine plasmacytoma.
1985
Conservation of sequence and structure flanking the mouse and human β-globin loci: The β-globin genes are embedded within an array of odorant receptor genes
1999 StandoutNobel
Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells.
1994
Age-Associated Increased Interleukin-6 Gene Expression, Late-Life Diseases, and Frailty
2000
The complete murine immunoglobulin class switch region of the alpha heavy chain gene-hierarchic repetitive structure and recombination breakpoints.
1993 StandoutNobel
Works of Sigrid Klein being referenced
Clinical Experience with CD3 X CD19 Bispecific Antibodies in Patients with B Cell Malignancies
1995
CD8 T cell activation after intravenous administration of CD3×CD19 bispecific antibody in patients with non-Hodgkin lymphoma
1995
Promotion of IL8, IL10, TNFα and TNFβ production by EBV infection
1996
Inhibition of Class Switch Recombination in Plasma Cells
1994
Heterogeneous expression of c-myb protein in human leukemia detected by simultaneous two color flow cytometric analysis
1992
Increased levels of circulating interleukin‐6 in patients with hodgkin's disease
1991
Release of Cytokines and Soluble Cell Surface Molecules by PBMC after Activation with the Bispecific Antibody CD3 × CD19
1997
Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures
1994
Evidence for transient requirement of the IgH enhancer
1985
Control of Immunoglobulin Class Switch Recombination
1986
Electron microscopic and immunolabeling studies of the lesional and normal skin of patients with mycosis fungoides treated by total body electron beam irradiation
1987
CD8 T cell activation after intravenous administration of CD3�CD19 bispecific antibody in patients with non-Hodgkin lymphoma
1995
Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant.
1984