Citation Impact
Citing Papers
Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling
2013 Science
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
2018 Science
Wnt5a–Ror–Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis
2012
Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice
2015
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size
2015
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation
2014
Inference and analysis of cell-cell communication using CellChat
2021 Standout
Ror2 Receptor Requires Tyrosine Kinase Activity to Mediate Wnt5A Signaling
2009
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Engineering precision nanoparticles for drug delivery
2020 Standout
WNT5A mutations in patients with autosomal dominant Robinow syndrome
2009
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
2014
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
2016 Standout
Atopic Dermatitis
2008 Standout
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Interactions between Hedgehog proteins and their binding partners come into view
2010
Autophagosomes form at ER–mitochondria contact sites
2013 StandoutNature
Brachy–syndactyly caused by loss of Sfrp2 function
2008
R-Loop Mediated trans Action of the APOLO Long Noncoding RNA
2020
Roles of RUNX in Hypoxia-Induced Responses and Angiogenesis
2017
Generation of a transgenic mouse model with chondrocyte‐specific and tamoxifen‐inducible expression of Cre recombinase
2007
Recent advances in BMP receptor signaling
2009
Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos
2011
The complex world of WNT receptor signalling
2012
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Histone lysine demethylases as targets for anticancer therapy
2013
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B
2010
Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells
2009 StandoutNobel
Glycan structures of the structural subunit (HtH1) of Haliotis tuberculata hemocyanin
2011
Genetic evidence that SOST inhibits WNT signaling in the limb
2010
Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice
2005
TGFβ signalling in context
2012 Standout
The emerging role of lncRNAs in cancer
2015 Standout
Gene deregulation in gastric cancer
2005
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Pulmonary Hypertension Due to BMPR2 Mutation: A New Paradigm for Tissue Remodeling?
2006
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla
2008 Nature
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING)
2017
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Cancer-associated cachexia
2018 Standout
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Dissection of Wnt5a-Ror2 Signaling Leading to Matrix Metalloproteinase (MMP-13) Expression
2011
Variants in a Novel Epidermal Collagen Gene (COL29A1) Are Associated with Atopic Dermatitis
2007
Mutation in WNT10A Is Associated with an Autosomal Recessive Ectodermal Dysplasia: The Odonto-onycho-dermal Dysplasia
2007
Sarcopenia
2019 Standout
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
GPR124 Functions as a WNT7-Specific Coactivator of Canonical β-Catenin Signaling
2014
The Sequence of a Gastropod Hemocyanin (HtH1 from Haliotis tuberculata)
2000
Agonists and Antagonists of TGF-β Family Ligands
2016
The Deleted in Brachydactyly B Domain of ROR2 Is Required for Receptor Activation by Recruitment of Src
2008
Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations
2013
Collagens
2009
Ext1-Dependent Heparan Sulfate Regulates the Range of Ihh Signaling during Endochondral Ossification
2004
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
2016 Standout
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Chapter 13 Long‐Range Gene Control and Genetic Disease
2008
Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus.
2004
Toll‐like receptor 4 contributes to poor outcome after intracerebral hemorrhage
2011 StandoutNobel
The neuronal endopeptidase ECEL1 is associated with a distinct form of recessive distal arthrogryposis
2012
Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing
2018 Standout
Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded
2010
Ror‐family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases
2009
Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C
2018
Long Noncoding RNAs: Cellular Address Codes in Development and Disease
2013 Standout
Spatial partitioning of the regulatory landscape of the X-inactivation centre
2012 StandoutNature
Update on Wnt signaling in bone cell biology and bone disease
2011
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Fragments of extracellular matrix as mediators of inflammation
2007
Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression
2013
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data
2013 Standout
Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression
2016
The archaeogastropod molluscHaliotis iris: tissue and blood metabolites and allosteric regulation of haemocyanin function
2002
Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development
2009
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development
2010 StandoutNobel
Copper Active Sites in Biology
2014 Standout
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development
2012 StandoutNobel
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases
2015 StandoutNobel
Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization
2010
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Zinc-Finger Transcription Factor Odd-Skipped Related 2 Is One of the Regulators in Osteoblast Proliferation and Bone Formation
2007
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis
2003
Collagen Structure and Stability
2009 Standout
Dose-Dependent Effects of Runx2 on Bone Development
2009
Non-Smad TGF-β signals
2005 Standout
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Towards an integrated view of Wnt signaling in development
2009
Wnt proteins synergize to activate β-catenin signaling
2017
Structures of two molluscan hemocyanin genes: Significance for gene evolution
2001
Long Non-Coding RNAs: Challenges for Diagnosis and Therapies
2013
Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis
2009
Specificity, versatility, and control of TGF-β family signaling
2019
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Mutations in HOXD13 Underlie Syndactyly Type V and a Novel Brachydactyly-Syndactyly Syndrome
2007
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
HIF1α regulation ofSox9is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis
2007
The Evolution of Extracellular Matrix
2010
The Orphan Receptor Tyrosine Kinase Ror2 Promotes Osteoblast Differentiation and Enhances ex Vivo Bone Formation
2006
Works of Sigmar Stricker being referenced
A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C
2010
Expression of Galectin-3 in Skeletal Tissues Is Controlled by Runx2
2003
Cloning and expression pattern of chicken Ror2 and functional characterization of truncating mutations in Brachydactyly type B and Robinow syndrome
2006
Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development
2017
Evolution of a Core Gene Network for Skeletogenesis in Chordates
2008
A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range
2009 Nature
The synpolydactyly homolog (spdh) mutation in the mouse – a defect in patterning and growth of limb cartilage elements
2002
Mutations in WNT7A Cause a Range of Limb Malformations, Including Fuhrmann Syndrome and Al-Awadi/Raas-Rothschild/Schinzel Phocomelia Syndrome
2006
Role of Runx Genes in Chondrocyte Differentiation
2002
Comparative expression pattern of Odd-skipped related genes Osr1 and Osr2 in chick embryonic development
2006
BMP signaling controls muscle mass
2013
Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2−/− mouse model
2006
A gradient of ROR2 protein stability and membrane localization confers brachydactyly type B or Robinow syndrome phenotypes
2009
A molecular pathogenesis for transcription factor associated poly-alanine tract expansions
2004
Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN
2009
Modulation of GDF5/BRI‐b signalling through interaction with the tyrosine kinase receptor Ror2
2004
A misplaced lncRNA causes brachydactyly in humans
2012
Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4
2008
Wnt-ligand-dependent interaction of TAK1 (TGF-β-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling
2008
Expression of Type XXIII Collagen mRNA and Protein
2006
Abalone (Haliotis tuberculata) hemocyanin type 1 (HtH1)
1999
Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation
2009
Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2
2003
Induction of Macrophage Chemotaxis by Aortic Extracts of the mgR Marfan Mouse Model and a GxxPG-Containing Fibrillin-1 Fragment
2006
Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region
2010
An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression
2005
Escobar Syndrome Is a Prenatal Myasthenia Caused by Disruption of the Acetylcholine Receptor Fetal γ Subunit
2006
Negative regulation of Wnt signaling mediated by CK1‐phosphorylated Dishevelled via Ror2
2010
The mutationROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome
2008