Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
2004 StandoutScience
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
p185neu expression in human lung adenocarcinomas predicts shortened survival.
1990
Early glandular neoplasia of the lung
2000
C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas.
1994
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
EGFR Antagonists in Cancer Treatment
2008 Standout
Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.
1992
Mutational activation of the K-ras oncogene and the effect of chemotherapy in advanced adenocarcinoma of the lung: a prospective study.
1997
K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
2008 Standout
RAS oncogenes: the first 30 years
2003
Analysis of the genome to personalize therapy for melanoma
2010
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
2013 StandoutNature
Wildtype Kras2 can inhibit lung carcinogenesis in mice
2001
Prognostic Markers in Resected Non–Small-Cell Lung Cancer: An Patients with 5 Year Follow-Up
1999
Atypical Adenomatous Hyperplasia of the Lung: A Probable Forerunner in the Development of Adenocarcinoma of the Lung
2001
K-rasOncogene Activation as a Prognostic Marker in Adenocarcinoma of the Lung
1990
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
The development and progression of adenocarcinoma of the lung
1994
The biology and management of non-small cell lung cancer
2018 StandoutNature
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
Lung Cancer
2008 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Renal-Cell Carcinoma
1996 Standout
A genetic model for colorectal tumorigenesis
1990 Standout
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
K‐ras mutations in human adenocarcinoma of the lung: Association with smoking and occupational exposure to asbestos
1993
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
RAS Is Regulated by the let-7 MicroRNA Family
2005 Standout
Mutations of epidermal growth factor receptor of non-small cell lung cancer were associated with sensitivity to gefitinib in recurrence after surgery
2005
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li–Fraumeni syndrome
1990 StandoutNature
All ras proteins are polyisoprenylated but only some are palmitoylated
1989 Standout
WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis
2009
Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer
2005 Standout
Suppression of lung adenocarcinoma progression by Nkx2-1
2011 Nature
Wnt/β-Catenin Signaling and Disease
2012 Standout
The molecular biology of breast cancer
1991
The p53 tumour suppressor gene
1991 StandoutNature
Smoking molecular damage in bronchial epithelium
2002
Increased expression of mutant forms of p53 oncogene in primary lung cancer
1990
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
1992 Standout
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
1997 Standout
Epidermal growth factor receptor abnormalities in lung cancer. Pathogenetic and clinical implications
2006
Emerging Biological Principles of Metastasis
2017 Standout
Promotion of Lung Carcinogenesis by Chronic Obstructive Pulmonary Disease–Like Airway Inflammation in a K-ras–Induced Mouse Model
2008
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1994 StandoutNature
KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib
2005
Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man
1994 Standout
Understanding resistance to EGFR inhibitors—impact on future treatment strategies
2010
Tobacco Smoke Carcinogens and Lung Cancer
1999 Standout
The ras gene family and human carcinogenesis
1988
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
1991 Standout
Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung
2001
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
2004
Gene-expression profiles predict survival of patients with lung adenocarcinoma
2002 Standout
DNA Synthesis and Repair Genes RRM1 and ERCC1 in Lung Cancer
2007
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
1988 Standout
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Analysis of oncogene alterations in human endometrial carcinoma: Prevalence of ras mutations
1991
Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse.
1989
p53 Mutations in Human Cancers
1991 StandoutScience
Small GTP-Binding Proteins
2001 Standout
Infrequent ras Oncogene Point Mutations in Renal Cell Carcinoma
1990
Cancer Metastasis: Experimental Approaches, Theoretical Concepts, and Impacts for Treatment Strategies
1985
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 Standout
Adenocarcinoma of the lung: its development and malignant progression
1993
Molecular mechanisms of oncogenesis.
1989
Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms
1990 StandoutScience
Small adenocarcinoma of the lung. Histologic characteristics and prognosis
1995 Standout
Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21
1990 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Growth Factors and Cancer
1991 StandoutScience
ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent.
1991
Missense mutations of the BRAF gene in human lung adenocarcinoma.
2002
p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines.
1991
Frequency and Distinctive Spectrum of KRAS Mutations in Never Smokers with Lung Adenocarcinoma
2008
ras oncogenes in human cancer: a review.
1989 Standout
BRAF and RAS mutations in human lung cancer and melanoma.
2002
LKB1 protein expression in the evolution of glandular neoplasia of the lung.
2003
Incidence of activating ras oncogene mutations associated with primary and metastatic human breast cancer.
1989
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
2004 Standout
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
Analysis of genetic alterations in renal cell carcinoma using the polymerase chain reaction
1994
Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53
1990 StandoutScience
The Differential Effects of Mutant p53 Alleles on Advanced Murine Lung Cancer
2005
Works of Siegina G. Evers being referenced
Cellular protoonocogenes are infrequently amplified in untreated non-small cell lung cancer
1989
K‐ ras oncogene activation in lung adenocarcinomas from former smokers evidence that K‐ ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung
1993
A Rapid and Simple Procedure for the Routine Detection of ras Point Mutations in Formalin-Fixed, Paraffin-Embedded Tissues
1992
A Rapid and Simple Procedure for the Routine Detection of ras Point Mutations in Formalin-Fixed, Paraffin-Embedded Tissues
1992
Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung.
1988
Outgrowth of grafts containing different ratios of hormone-dependent and independent mouse mammary tumor cells
1981
Mutational Activation of the K-rasOncogene
1987