Standout Papers
Citation Impact
Citing Papers
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
2009 Standout
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Preparation, dissolution and characterization of albendazole solid dispersions
1996
Population pharmacokinetics of the photodynamic therapy agent 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a in cancer patients.
2003
Pharmacokinetic Study of Omeprazole in Elderly Healthy Volunteers
1992
Concurrent Cisplatin-Based Radiotherapy and Chemotherapy for Locally Advanced Cervical Cancer
1999 Standout
Myopia
2012 Standout
Evaluation of aspirin metabolites as inhibitors of hypoxia-inducible factor hydroxylases
2008 StandoutNobel
Role of transport proteins in drug absorption, distribution and excretion
2001
The role of porphyrin chemistry in tumor imaging and photodynamic therapy
2010 Standout
Valvular Heart Disease Associated with Fenfluramine–Phentermine
1997 Standout
Improving drug solubility for oral delivery using solid dispersions
2000 Standout
Antibiotic Treatment ofChlamydia pneumoniaeafter Acute Coronary Syndrome
2005 Standout
Physicochemical characterization and in vivo properties of Zolpidem in solid dispersions with polyethylene glycol 4000 and 6000
1999
Occurrence, fate and transformation of emerging contaminants in water: An overarching review of the field
2017
Effects of Computerized Clinical Decision Support Systems on Practitioner Performance and Patient Outcomes
2005 Standout
Non-compliance—or how many aunts has Matilda?
1993 Standout
Amorphous pharmaceutical solids: preparation, characterization and stabilization
2001 Standout
Modification of Rectal Absorption of Morphine Hollow-Type Suppositories with a Combination of α‐Cyclodextrin and Viscosity-Enhancing Pol ysacc haride
1995
Theophylline concentrations in patients with acute exacerbation of COPD
1990
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
In Vivo Ligand Specificity of E-selectin Binding to Multivalent Sialyl Lewisx N-linked Oligosaccharides
1999
Amorphous Drug Delivery Systems: Molecular Aspects, Design, and Performance
2004
Clinical Implications of Prostaglandin and Thromboxane A2Formation
1988
Improvement of the diuretic effect of triamterene via solid dispersion technique with PEG 4000
1994
Long-term Proton Pump Inhibitor Therapy and Risk of Hip Fracture
2006 Standout
Pharmaceutical intervention for myopia control
2010
Structure-antioxidant activity relationships of flavonoids and phenolic acids
1996 Standout
Spectroscopic Characterization of Interactions Between PVP and Indomethacin in Amorphous Molecular Dispersions
1997
A Randomized, Controlled Trial of Theophylline in Patients with Severe Chronic Obstructive Pulmonary Disease
1989
Drug assay using antibody mimics made by molecular imprinting
1993 StandoutNature
Acne vulgaris
2011 Standout
Polyphenols: food sources and bioavailability
2004 Standout
The Pharmacokinetics of Vecuronium in Male and Female Patients
1998
Sufficient levels of quinine in the serum circumvent the multidrug resistance of the human leukemic cell line K562/ADM
1991
The biochemistry and toxicology of benzoic acid metabolism and its relationship to the elimination of waste nitrogen
1993
Clinical Implications of Prostaglandin and Thromboxane A2Formation
1988
Regulatory Functions of the Vascular Endothelium
1990 StandoutNobel
Paresis Acquired in the Intensive Care Unit<SUBTITLE>A Prospective Multicenter Study</SUBTITLE>
2002 Standout
Computer-assisted optimization of aminophylline therapy in the emergency department
1989
Preparation, Characterization, and Dissolution Studies of Ibuprofen Solid Dispersions Using Polyethylene Glycol (PEG), Talc, and PEG-Talc as Dispersion Carriers
1998
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Concurrent daily carboplatin and accelerated hyperfractionated thoracic radiotherapy in locally advanced nonsmall cell lung cancer
1997
Physical Properties of Solid Molecular Dispersions of Indomethacin with Poly(vinylpyrrolidone) and Poly(vinylpyrrolidone-co-vinyl-acetate) in Relation to Indomethacin Crystallization
1999
A Simple HPLC–UV Method for the Quantification of Theophylline in Rabbit Plasma and its Pharmacokinetic Application
2015
Effect of Multiple‐Dose Gatifloxacin or Ciprofloxacin on Glucose Homeostasis and Insulin Production in Patients with Noninsulin‐Dependent Diabetes Mellitus Maintained with Diet and Exercise
2000
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
2001 Standout
Direct enantiomeric separations by high performance liquid chromatography using cyclodextrins
1997
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
1993 Standout
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
2014 Standout
Excretion of ciprofloxacin in sweat and multiresistant Staphylococcus epidermidis
1997
Improved Oral Absorption of Enteric Coprecipitates of a Poorly Soluble Drug
1994
Carbonic Anhydrase Inhibitors: Synthesis of Sulfonamides Incorporating 2, 4, 6–Trisubstituted-Pyridinium-Ethylcarboxamido Moieties Possessing Membrane-Impermeability and in Vivo Selectivity for the Membrane-Bound (CA IV) Versus the Cytosolic (CA I and CA II) Isozymes
2000
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms
2010 Standout
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2001 Standout
Anti‐remodelling effect of canrenone in patients with mild chronic heart failure (AREA IN‐CHF study): final results
2009
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Characterization and dissolution behavior of nifedipine and phosphatidylcholine binary systems
1996
Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability
1989 Standout
The Activation of Carboxylic Acids via Self-Assembly Asymmetric Organocatalysis: A Combined Experimental and Computational Investigation
2016 StandoutNobel
Dissolution Behavior of Griseofulvin Solid Dispersions Using Polyethylene Glycol, Talc, and Their Combination as Dispersion Carriers
1996
Inhibitory effects of water-soluble polymers on precipitation of RS-8359
1997
Investigation of formulation approaches to improve the dissolution of SB-210661, a poorly water soluble 5-lipoxygenase inhibitor
1998
Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000: A National Reconnaissance
2002 Standout
Application of a Radiotelemetric System to Evaluate the Performance of Enteric Coated and Plain Aspirin Tablets
1986
Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
1991 Standout
Physical characteristics and dissolution kinetics of solid dispersions of ketoprofen and polyethylene glycol 6000
1994
Evaluation of a scheme for establishing and maintaining dosage of theophylline in ambulatory patients with chronic asthma
1986
Understanding the Dose-Effect Relationship
1981
Caffeine and Pharmaceuticals as Indicators of Waste Water Contamination in Wells
1999
Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.
1994 Standout
Ketoprofen: A Review of Its Pharmacologic and Clinical Properties
1986
Noncompartmental Determination of the Steady-State Volume of Distribution for Any Mode of Administration
1982 Standout
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.
1987 StandoutNobel
Absorption and dissolution of nitrofurantoin from different experimental formulations
1984
NL-FIT: A microcomputer program for non-linear fitting
1983
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Effects of parathyroid hormone on plasma and urinary adenosine 3′,5′-monophosphate in man
1970 StandoutNobel
Cyclodextrin Drug Carrier Systems
1998 Standout
Review: A History of Cyclodextrins
2014 Standout
Pharmacokinetics of absorption, distribution and elimination of fenfluramine and its main metabolite in man
1972
Improvement of the dissolution kinetics of SR 33557 by means of solid dispersions containing PEG 6000
1995
Effects of glucagon on adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate in human plasma and urine
1970 StandoutNobel
Drug Solubility: Importance and Enhancement Techniques
2012 Standout
Biological Feedbacks in Global Desertification
1990 StandoutScience
Furosemide Absorption Altered in Decompensated Congestive Heart Failure
1985
The properties of solid dispersions of indomethacin or phenylbutazone in polyethylene glycol
1986
The In-vitro pH-Dissolution Dependence and In-vivo Bioavailability of Frusemide-PVP Solid Dispersions
1989
Enhanced Dissolution of Ursodeoxycholic Acid from the Solid Dispersion
1997
Characterization and dissolution of fenofibrate solid dispersion systems
1994
Monitoring Serum Theophylline Levels
1978
The effect of wetting agents on the dissolution of indomethacin solid dispersion systems
1986
Quantitative determination of D- and L-amino acids by reaction with tert-butyloxycarbonyl-L-leucine N-hydroxysuccinimide ester and chromatographic separation as L,D and L,L dipeptides
1978 StandoutNobel
Dose-Related Kinetics of Aspirin
1984
Relationship Between Drug Concentration in Plasma or Serum and Amount of Drug in the Body
1969
The Pharmacokinetics of Non-Steroidal Anti-Inflammatory Drugs in the Elderly
1987
Kinetic parameters and renal clearances of plasma adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate in man
1970 StandoutNobel
Ultrasound-mediated gastrointestinal drug delivery
2015
Michaelis-Menten pharmacokinetics of diphenylhydantoin and application in the pediatric age patient
1980
Physicochemical aspects of drug release. XIV. The effects of some ionic and non-ionic surfactants on properties of a sparingly soluble drug in solid dispersions
1992
Dissolution rates of partially water-soluble drugs from solid dispersion systems. I. Prednisolone
1987
Improved dissolution of ofloxacin via solid dispersion
1997
HPLC‐Fluorescence Method for the Enantioselective Analysis of Propranolol in Rat Serum Using Immobilized Polysaccharide‐Based Chiral Stationary Phase
2014
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Amorphous spironolactone-hydroxypropylated cyclodextrin complexes with superior dissolution and oral bioavailability
1997
Thermal Behavior and Dissolution Properties of Naproxen From Binary and Ternary Solid Dispersions
1999
Preformulation study of etoposide: II. Increased solubility and dissolution rate by solid-solid dispersions
1995
Determination of theophylline in plasma ultrafiltrate by reversed phase high pressure liquid chromatography
1976
Intestinal Drug Absorption and Metabolism III: Glycine Conjugation and Accumulation of Benzoic Acid in Rat Intestinal Tissue
1971
Pharmacokinetics of Gentamicin in Children and Adults
1975
Disposition of quercetin in man after single oral and intravenous doses
1975
Effects of Theophylline on Diaphragmatic Strength and Fatigue in Patients with Chronic Obstructive Pulmonary Disease
1984
Effect of polyvinylpyrrolidone on the crystallinity and dissolution rate of solid dispersions of the antiinflammatory CI-987
1994
An evaluation of the potential use of isoniazid, acetylisoniazid and isonicotinic acid for monitoring the self‐administration of drugs.
1980
Age-related differences in salicylamide and acetaminophen conjugation in man
1977 StandoutNobel
Similarities in the release rates of different drugs from polyethylene glycol 6000 solid dispersions
1985
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Dissolution kinetics of piroxicam in solid dispersions with polyethylene glycol 4000
1993
Absorption Potential: Estimating the Fraction Absorbed for Orally Administered Compounds
1985
Polymerized Liposome Assemblies: Bifunctional Macromolecular Selectin Inhibitors Mimicking Physiological Selectin Ligands
2001 StandoutNobel
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Effect of Mode of Administration on Drug Distribution in a Two-Compartment Open System
1969
Pharmacotherapy of Respiratory Muscles
1988
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Sidney Riegelman being referenced
Disposition of caffeine and its metabolites in man.
1983
Stereospecific assay for (-)- and (+)-propranolol in human and dog plasma.
1980
Fluorometric Microassay for Spironolactone and Its Metabolites in Biological Fluids
1972
Preparation and Dissolution Characteristics of Several Fast-Release Solid Dispersions of Griseofulvin
1969
The clinical pharmacokinetics of phenytoin
1977
The effect of quinidine and its metabolites on the electrocardiogram and systolic time intervals: concentration‐effect relationships.
1981
Effect of erythromycin on theophylline kinetics
1981
Simultaneous determination of theophylline and its major metabolites in urine by reversed-phase ion-pair high-performance liquid chromatography
1980
Increased Dissolution Rates of Water-Insoluble Cardiac Glycosides and Steroids via Solid Dispersions in Polyethylene Glycol 6000
1971
Quinidine pharmacokinetics in man: Choice of a disposition model and absolute bioavailability studies
1979
Pharmacokinetics of Acetylsalicylic Acid and Salicylic Acid After Intravenous Administration in Man
1968
Pharmacokinetics of isoniazid and some metabolites in man
1976
Renal contribution to overall metabolism of drugs I: Conversion of benzoic acid to hippuric acid
1972
Statistical estimations in pharmacokinetics
1974
The application of statistical moment theory to the evaluation ofin vivo dissolution time and absorption time
1980 Standout
Intestinal Drug Absorption and Metabolism I: Comparison of Methods and Models to Study Physiological Factors of In Vitro and In Vivo Intestinal Absorption
1970
Absorption Characteristics of Solid Dispersed and Micronized Griseofulvin in Man
1971
Shortcomings in Pharmacokinetic Analysis by Conceiving the Body to Exhibit Properties of a Single Compartment
1968
Pharmacokinetics of quinidine and three of its metabolites in man
1984
Assessment of Pharmacokinetic Constants from Postinfusion Blood Curves Obtained after I.V. Infusion
1970
Intestinal Drug Absorption and Metabolism II: Kinetic Aspects of Intestinal Glucuronide Conjugation
1970
Plasma Levels of Spirolactones in the Dog
1972
Theophylline disposition in acutely ill hospitalized patients. The effect of smoking, heart failure, severe airway obstruction, and pneumonia.
1978
Pharmaceutical Applications of Solid Dispersion Systems
1971 Standout
Influence of the Route of Administration on the Area Under the Plasma Concentration-Time Curve
1969
Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine
1980
Role of Sweat in Accumulation of Orally Administered Griseofulvin in Skin
1974
Stereoselective Disposition and Glucuronidation of Propranolol in Humans
1982
Ketoprofen pharmacokinetics and bioavailability based on an improved sensitive and specific assay
1981
Uptake of Acetazolamide by Human Erythrocytes In Vitro
1977
Oral Absorption of Griseofulvin in Dogs: Increased Absorption via Solid Dispersion - in Polyethylene Glycol 6000
1970
GLC Determination of Theophylline in Biological Fluids
1974
Dose-dependent kinetics for theophylline: Observations among ambulatory asthmatic children
1980
A New Stabilized Form of Epinephrine for the Treatment of Open-Angle Glaucoma
1961
Rational Use of Theophylline for Bronchodilatation
1974
New Method for Calculating the Intrinsic Absorption Rate of Drugs
1968
Absorption Kinetics of Aspirin in Man follow Oral Administration of an Aqueous Solution
1972
Concept of a Volume of Distribution and Possible Errors in Evaluation of This Parameter
1968