Standout Papers
- Identification of ribonuclease P activity from chick embryos (1980)
- Characterization in vitro of the defect in a temperature-sensitive mutant of the protein subunit of RNase P from Escherichia coli (1989)
- Partial purification and properties of an endoribonuclease isolated from human KB cells. (1975)
- Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells. (1989)
- Role in translation of a triple tandemly repeated sequence in the 5′-untranslated region of human thymidylate synthase mRNA (1987)
- Coding properties of an ochre-suppressing derivative of Escherichia coli tRNAITyr (1977)
- Identification of a ribonuclease P-like activity from human KB cells (1976)
- Properties of purified ribonuclease P from Escherichia coli (1981)
- Site-directed mutagenesis of M1 RNA, the RNA subunit of Escherichia coli ribonuclease P (1986)
- An E. coli gene coding for a protamine-like protein (1981)
- Ribonuclease P: An Enzyme with a Catalytic RNA Subunit (1989)
- The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme (1983)
- Veal heart ribonuclease P has an essential RNA component (1980)
- Characteristics of Ribonuclease P from Various Organisms (1987)
- Transfer RNA processing enzymes (1981)
- CONTEXT EFFECTS ON NONSENSE CODON SUPPRESSION IN ESCHERICHIA COLI (1978)
- An immunological determinant of RNase P protein is conserved between Escherichia coli and humans. (1989)
- The recognition by RNase P of precursor tRNAs. (1988)
- A T4-Induced Endonuclease Which Attacks T4 DNA (1970)
- Purification and Properties of a Specific Escherichia coli Ribonuclease which Cleaves a Tyrosine Transfer Ribonucleic Acid Precursor (1972)
- Catalysis by the RNA subunit of RNase P — a minireview (1989)
- M1 RNA with large terminal deletions retains its catalytic activity (1986)
- RNA's as catalysts: A new class on enzymes (1987)
- Identification of an ochre-suppressing anticodon (1971)
- Specific Interactions in RNA Enzyme-Substrate Complexes (1989)
- A G43 to U43 mutation in E. coli tRNATyrsu3+ which affects processing by RNase P (1983)
- Biosynthesis of Transfer RN (1981)
- Enzymatic cleavage of RNA by RNA (1986)
- E. coli RNAase P has a required RNA component in vivo (1980)
- Kinetics and intermediates in the intracellular synthesis of bacteriophage T4 deoxyribonucleic acid (1970)
- Biosynthesis of transfer RNA in Escherichia coli (1975)
- Selection and characterization of randomly produced mutants in the gene coding for M1 RNA (1988)
- Suppressor and novel mutants of bacteriophage T4 tRNAGly (1987)
- Isolation of Tyrosine tRNA Precursor Molecules (1971)
- RNA precursor molecules and ribonucleases in E. coli (1973)
- Nucleotide Modification In Vitro of the Precursor of Transfer RNA Tyr of Escherichia coli (1973)
- A modified uridine in the anticodon of E. coli $${\hbox{ tRNA }}_{\hbox{ 1 }}^{\hbox{ Tyr }}\hbox{ \hspace }{\hbox{ su }}_{\hbox{ oc }}^ $$ (1976)
- Ribonuclease P substrate specificity: cleavage of a bacteriophage phi80-induced RNA. (1976)
- Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA. (1976)
- Endoribonuclease activity associated with animal RNA viruses (1978)
- Reconstitution of RNAase P activity using inactive subunits from E. coli and HeLa cells (1986)
- Aspects of biochemical catalysis (1984)
- Heterologous enzyme function in Escherichia coli and the selection of genes encoding the catalytic RNA subunit of RNase P. (1987)
- Nucleotide sequence of the gene encoding the RNA subunit (M1 RNA) of ribonuclease P from Escherichia coli (1982)
- RNA-processing Nucleases (1982)
- Identification of precursor molecules to individual tRNA species from Bombyx mori. (1978)
- Identification of tRNA Precursor Molecules made by Phage T4 (1973)
- Influence of the A15 mutation on the conformational energy balance in Escherichia coli tRNATyr (1977)
- M1 RNA, the RNA subunit of Escherichia coli ribonuclease P, can undergo a pH-sensitive conformational change (1986)
- Effects of 9-aminoacridine on bacteriophage T4 deoxyribonucleic acid synthesis (1970)
- Repeated sequences and open reading frames in the 3' flanking region of the gene for the RNA subunit of Escherichia coli ribonuclease P. (1983)
- Reaction in vitro of some mutants of RNase P with wild-type and temperature-sensitive substrates (1989)
- Model Substrates for an RNA Enzyme (1987)
- Antibodies in human serum that precipitate ribonuclease P. (1988)
- Differential effects of mutations in the protein and RNA moieties of RNase P on the efficiency of suppression by various tRNA suppressors (1988)
- Tyrosine tRNA Precursor Molecule Polynucleotide Sequence (1971)
- Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli (1986)
- Novel reactions of RNAase P with a tRNA-like structure in turnip yellow mosaic virus RNA (1988)
- A Catalytic RNA and Its Gene from Salmonella typhimurium (1985)
- Structure in solution of M1 RNA, the catalytic subunit of ribonuclease P from Escherichia coli (1984)
- Large deletion mutants of Escherichia coli tRNA1Tyr (1982)
- Characterization of ribonuclease NU cleavage sites in a bacteriophage phi80-induced ribonucleic acid. (1975)
- Aspects of RNase P Structure and Function (1980)
- Characterization of an RNase P activity from HeLa cell mitochondria. Comparison with the cytosol RNase P activity. (1985)
- Ribonuclease P: an enzyme with an essential RNA component. (1978)
- Processing of E. coli tRNA Tyr precursor RNA in vitro. (1975)
- Reconstitution of RNase P activity from inactive RNA and protein. (1979)
- Catalytic Activity of an RNA Molecule Prepared by Transcription in Vitro (1984)
- In vitro processing of B. mori transfer RNA precursor molecules (1979)
- Affinity chromatography with an immobilized RNA enzyme. (1986)
- Cleavage of tRNA precursors by the RNA subunit of E. coli ribonuclease P (M1 RNA) is influenced by 3′-proximal CCA in the substrates (1984)
Citation Impact
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The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
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Phylogenetic comparative analysis and the secondary structure of ribonuclease P RNA — a review
1989
Deoxyribozymes: DNA catalysts for bioorganic chemistry
2004
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Rapid kinetic characterization of hammerhead ribozymes by real-time monitoring of fluorescence resonance energy transfer (FRET)
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1998
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2013
The involvement of RNA in ribosome function
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New loop-loop tertiary interactions in self-splicing introns of subgroup IC and ID: a complete 3D model of the Tetrahymena thermophila ribozyme
1996
Metal coordination sites that contribute to structure and catalysis in the group I intron from Tetrahymena
1993
RNA-catalysed synthesis of complementary-strand RNA
1989 StandoutNatureNobel
Phylogenetic-comparative analysis of the eukaryal ribonuclease P RNA
2000
A DNA enzyme that cleaves RNA
1994
In vitro selection of RNA molecules that bind specific ligands
1990 StandoutNatureNobel
A model for RNA editing in kinetoplastid mitochondria: RNA molecules transcribed from maxicircle DNA provide the edited information
1990
Substrate masking: binding of RNA by EGTA-inactivated micrococcal nuclease results in artifactual inhibition of RNA processing reactions
1990
Design of RNA enzymes distinguishing a single base mutation in RNA
1989
A novel mode of regulation of an RNA-cleaving DNAzyme by effectors that bind to both enzyme and substrate
2001
Multiple magnesium ions in the ribonuclease P reaction mechanism
1993
Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage
2000
Deoxyribozymes: useful DNA catalysts in vitro and in vivo
2008
A site-specific self-cleavage reaction performed by a novel RNA in neurospora mitochondria
1990
Catalytic DNA (deoxyribozymes) for synthetic applications—current abilities and future prospects
2008
Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain
1992
Eukaryotic ribonuclease P: Increased complexity to cope with the nuclear pre-tRNA pathway
2001
In vitro selection of self-cleaving DNAs
1996
Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features
1998 Nobel
Simple RNA enzymes with new and highly specific endoribonuclease activities
1988 Nature
Derivation of the three-dimensional architecture of bacterial ribonuclease P RNAs from comparative sequence analysis
1998
Real-Time Kinetics of Gene Activity in Individual Bacteria
2005 Standout
Structure‐Switching Signaling Aptamers: Transducing Molecular Recognition into Fluorescence Signaling
2004
Role of divalent metal ions in the hammerhead RNA cleavage reaction
1991
RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme
1992 Nature
In Vitro Selection of Nucleic Acid Enzymes
1999
In vitro selection of RNA aptamers specific for cyanocobalamin
1994 StandoutNobel
Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity
1990 Nature
Protein facilitation of group I intron splicing by assembly of the catalytic core and the 5′ splice site domain
1995 Nobel
Binding Stoichiometry of an RNA Aptamer and Its Transcription Factor Target
2002
In vitro evolution of new ribozymes with polynucleotide kinase activity
1994 StandoutNatureNobel
Ribozyme-mediated repair of defective mRNA by targeted trans-splicing
1994 NatureNobel
Dissecting metal ion–dependent folding and catalysis of a single DNAzyme
2007
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Emerging clinical applications of RNA
2002 Nature
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
1989 StandoutNatureNobel
Site‐specific cleavage reaction catalyzed by leadzyme is enhanced by combined effect of lead and rare earth ions
1996
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
A Mutational Analysis of the 8–17 Deoxyribozyme Core
2005
Presence of a coordinated metal ion in a trans-acting antigenomic delta ribozyme
1999
Aptamers come of age – at last
2006
Evidence for the metal-cofactor independence of an RNA phosphodiester-cleaving DNA enzyme
1997
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
Bacterial Small RNA Regulators: Versatile Roles and Rapidly Evolving Variations
2010
An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme
1993
RNA evolution and the origins of life
1989 Nature
Chemical synthesis of biologically active oligoribonucleotides using β-cyanoethyl protected ribonucleoside phosphoramidites
1990
RNA tectonics: towards RNA design
1996
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for Pre-mRNA splicing in vitro
1985
Autolytic Processing of Dimeric Plant Virus Satellite RNA
1986 Science
A mechanism for RNA splicing.
1980
A model for the RNA-catalyzed replication of RNA.
1986 StandoutNobel
The 40-kilodalton to autoantigen associates with nucleotides 21 to 64 of human mitochondrial RNA processing/7-2 RNA in vitro.
1991
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
Functional Nucleic Acid Sensors
2009 Standout
RNA Editing—A Novel Genetic Phenomenon?
1990 Science
Defining the Inside and Outside of a Catalytic RNA Molecule
1989 StandoutScienceNobel
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites
1987
Thermus thermophilus 16S rRNA is transcribed from an isolated transcription unit
1989
Suppressors in Yeast
1974
MECHANISTIC ASPECTS OF ENZYMATIC CATALYSIS: Lessons from Comparison of RNA and Protein Enzymes
1997
Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
1984 Standout
Ribonuclease P Catalysis Differs from Ribosomal RNA Self-Splicing
1985 Science
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
Characterization of functionally active subribosomal particles from Thermus aquaticus
1999
Capturing the Structure of a Catalytic RNA Intermediate: The Hammerhead Ribozyme
1996 ScienceNobel
The 3′-5′ exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.
1991
Ion dependence of the Bacillus subtilis RNase P reaction.
1985
Visualizing the Higher Order Folding of a Catalytic RNA Molecule
1991 ScienceNobel
A general two-metal-ion mechanism for catalytic RNA.
1993 StandoutNobel
Self-Splicing RNA: Implications for Evolution
1985 StandoutNobel
Zn2+-Dependent Deoxyribozymes That Form Natural and Unnatural RNA Linkages
2005
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing
1987 Nature
Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs.
1983
A general purpose RNA-cleaving DNA enzyme
1997
RNase P of Bacillus subtilis has a RNA component.
1980
The new frontier of genome engineering with CRISPR-Cas9
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Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA
1985
Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid
1986
Self-splicing of yeast mitochondrial ribosomal and messenger RNA precursors
1985
Why Nature Chose Phosphates
1987 StandoutScience
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Rna catalysis and the origin of life
1985
Small nuclear ribonucleoprotein particle assembly in vivo: Demonstration of a 6S RNA-free core precursor and posttranslational modification
1985 StandoutNobel
Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon
1976 Nature
Chance and Necessity in the Selection of Nucleic Acid Catalysts
1996 StandoutNobel
Movement of the Guide Sequence During RNA Catalysis by a Group I Ribozyme
1993 ScienceNobel
An enhancer screen identifies a gene that encodes the yeast U1 snRNP A protein: implications for snRNP protein function in pre-mRNA splicing.
1993 StandoutNobel
Are snRNPs involved in splicing?
1980 Nature
Distinctive sequence of human mitochondrial ribosomal RNA genes
1980 Nature
RNA-Protein Interactions in 30 S Ribosomal Subunits: Folding and Function of 16 S rRNA
1989 Science
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
Precise localization and nucleotide sequence of the two mouse mitochondrial rRNA genes and three immediately adjacent novel tRNA genes
1980
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.
1978 StandoutNobel
The Intervening Sequence RNA of Tetrahymena Is an Enzyme
1986 StandoutScienceNobel
Temperature sensitive mutants of Escherichia coli for tRNA synthesis
1974
A Labile Phosphodiester Bond at the Ligation Junction in a Circular Intervening Sequence RNA
1984 StandoutScienceNobel
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA
1984 StandoutNatureNobel
Reversibility of cyclization of the tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice
1985 StandoutNobel
The Tetrahymena ribozyme acts like an RNA restriction endonuclease
1986 StandoutNatureNobel
Modern metabolism as a palimpsest of the RNA world.
1989
RNA catalysis and the origins of life
1986
Reactions of the intervening sequence of the Tetrahymena ribosomal ribonucleic acid precursor: pH dependence of cyclization and site-specific hydrolysis
1985 StandoutNobel
Influence of metal ions on the ribonuclease P reaction. Distinguishing substrate binding from catalysis.
1992
Speculations on the early course of evolution.
1986
Ribozymes: A Distinct Class of Metalloenzymes
1993 Science
Sequence and organization of the human mitochondrial genome
1981 StandoutNatureNobel
Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains.
1990 StandoutNobel
Expanding the Scope of RNA Catalysis
1994 Science
Site-specific polyadenylation in a cell-free reaction
1984
Functional reconstitution of wild-type and mutant Tetrahymena telomerase.
1994 StandoutNobel
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus
1979
RNAs with Dual Specificity and Dual RNAs with Similar Specificity
1994 Science
Origin of life: The RNA world
1986 StandoutNatureNobel
Satellite tobacco ringspot virus RNA: A subset of the RNA sequence is sufficient for autolytic processing
1986
A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences.
1981
Reconstitution of a group I intron self-splicing reaction with an activator RNA.
1991
Cocrystal structure of an editing complex of Klenow fragment with DNA.
1988
A suppressor mutation in the nematode acting on specific alleles of many genes
1978 StandoutNatureNobel
Unusual Resistance of Peptidyl Transferase to Protein Extraction Procedures
1992 Science
Ribozyme Structures and Mechanisms
2000 StandoutNobel
Directed Evolution of Nucleic Acid Enzymes
2004
Messenger RNA Degradation in Bacterial Cells
2014
The Tetrahymena intervening sequence ribonucleic acid enzyme is a phosphotransferase and an acid phosphatase
1986 StandoutNobel
Crystal Structure of a Conserved Ribosomal Protein-RNA Complex
1999 Science
Partial purification of RNase P from Schizosaccharomyces pombe.
1981
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Mapping the active site of ribonuclease P RNA using a substrate containing a photoaffinity agent.
1990
Total chemical synthesis of a ribozyme derived from a group I intron.
1995 StandoutNobel
The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors
1984
A System for Stable Expression of Short Interfering RNAs in Mammalian Cells
2002 StandoutScience
Gene regulation by riboswitches
2004
Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site
1987
tRNA punctuation model of RNA processing in human mitochondria
1981 StandoutNature
Transfer ribonucleic acid biosynthesis. Substrate specificity of ribonuclease P.
1976
Ribozyme Structures and Mechanisms
2001 StandoutNobel
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine
1977 StandoutNobel
Ribozyme inhibitors. Deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor
1986 StandoutNobel
Functional Nucleic Acids for Analytical Applications
2009
Disassembly and reconstitution of signal recognition particle
1983 StandoutNobel
Mechanisms of Suppression
1973
RIBONUCLEASE P: Unity and Diversity in a tRNA Processing Ribozyme
1998
Structure and function of telomeres
1991 StandoutNatureNobel
Catalytic activity of the nucleic acid component of the 1,4-α-glucan branching enzyme from rabbit muscles
1987
Selection of an RNA domain that binds Zn2+.
1995
Small Stable RNAs from Escherichia coli : Evidence for the Existence of New Molecules and for a New Ribonucleoprotein Particle Containing 6S RNA
1978
Ribonuclease P: function and variation.
1990
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U
1984
Primary Structure of the Nucleic Acid from the 1,4-α-Glucan Branching Enzyme
1979
Creative catalysis: pieces of the RNA world jigsaw
2001 StandoutNobel
Self cleavage of a precursor RNA from bacteriophage T4
1984
Molecular relationships between two nuclear antigens, ribonucleoprotein and Sm: purification of active antigens and their biochemical characterization
1981
A mammalian Mitochondrial RNA Processing Activity Contains Nucleus-Encoded RNA
1987 Science
Aminoacyl Esterase Activity of the Tetrahymena Ribozyme
1992 ScienceNobel
A self-splicing RNA excises an intron lariat
1986
Works of Sidney Altman being referenced
A view of RNase P
2007
Aspects of RNase P Structure and Function
1980 Standout
RNA-processing Nucleases
1982 Standout
Saccharomyces cerevisiaeにおいて,核RNアーゼPの必須蛋白質サブユニットであるRpp2は前駆体tRNAと35S前駆体rRNAのプロセシングに必要である
1998
Enzymatic Cleavage of RNA by RNA (Nobel Lecture)
1990
Mapping in Three Dimensions of Regions in a Catalytic RNA Protected from Attack by an Fe(II)-EDTA Reagent
1996
Protection from chemical modification of nucleotides in complexes of M1 RNA, the catalytic subunit of RNase P from E coli, and tRNA precursors
1990
Mapping RNA-protein interactions in ribonuclease P from Escherichia coli using disulfide-linked EDTA-fe 1 1Edited by K. Nagai
2000
Analysis of the functional role of conserved residues in the protein subunit of ribonuclease P from Escherichia coli
1997
Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA inSaccharomyces cerevisiae
1997
Ribonuclease P: An Enzyme with a Catalytic RNA Subunit
1989 Standout
Rpp14 and Rpp29, two protein subunits of human ribonuclease P
1999
Kinetics of the processing of the precursor to 4·5 S RNA, a naturally occurring substrate for RNase P from Escherichia coli
1991
Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA inSaccharomyces cerevisiae
1997
A physical assay for and kinetic analysis of the interactions between M1 RNA and tRNA precursor substrates
1993
Selection and characterization of randomly produced mutants in the gene coding for M1 RNA
1988 Standout
The RNA Subunit of Ribonuclease P from the Zebrafish, Danio rerio
1996
Interaction of RNase P fromEscherichia coliwith pseudoknotted structures in viral RNAs
1990
Similar cage-shaped structures for the RNA components of all ribonuclease P and ribonuclease MRP enzymes
1990
Novel reactions of RNAase P with a tRNA-like structure in turnip yellow mosaic virus RNA
1988 Standout
Differential effects of mutations in the protein and RNA moieties of RNase P on the efficiency of suppression by various tRNA suppressors
1988 Standout
Catalysis by the RNA subunit of RNase P — a minireview
1989 Standout
Important 2′-hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli
1992
Structure and transcription of a human gene for H1 RNA, the RNA component of human RNase P
1990
Reaction in vitro of some mutants of RNase P with wild-type and temperature-sensitive substrates
1989 Standout
Varieties of RNase P: A nomenclature problem?
2000
Gel Retardation Analysis of the Interaction between C5 Protein and M1 RNA in the Formation of the Ribonuclease P Holoenzyme from Escherichia coli
1994
Characteristics of Ribonuclease P from Various Organisms
1987 Standout
Pathway of Activation by Magnesium Ions of Substrates for the Catalytic Subunit of RNase P from Escherichia coli
1993
Fluorescence properties of a tryptophan residue in an aromatic core of the protein subunit of ribonuclease P from Escherichia coli
1997
Twenty years
2015
Identification of ribonuclease P activity from chick embryos
1980 Standout
Effective inhibition of influenza virus production in cultured cells by external guide sequences and ribonuclease P
1998
Identification of an ochre-suppressing anticodon
1971 StandoutNobel
Ribonuclease P: an enzyme with an essential RNA component.
1978 Standout
In vitro processing of B. mori transfer RNA precursor molecules
1979 Standout
Biosynthesis of transfer RNA in Escherichia coli
1975 Standout
A subunit of human nuclear RNase P has ATPase activity
2001
A modified uridine in the anticodon of E. coli $${\hbox{ tRNA }}_{\hbox{ 1 }}^{\hbox{ Tyr }}\hbox{ \hspace }{\hbox{ su }}_{\hbox{ oc }}^ $$
1976 Standout
Polarity Effects in the Lactose Operon of Escherichia coli
2004
Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P.
1998
Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA.
1976 Standout
Veal heart ribonuclease P has an essential RNA component
1980 Standout
External Guide Sequences for an RNA Enzyme
1990 Science
Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae
1998
Ribonuclease P substrate specificity: cleavage of a bacteriophage phi80-induced RNA.
1976 Standout
Isolation of Tyrosine tRNA Precursor Molecules
1971 Standout
M1 RNA, the RNA subunit of Escherichia coli ribonuclease P, can undergo a pH-sensitive conformational change
1986 Standout
A Catalytic RNA and Its Gene from Salmonella typhimurium
1985 StandoutScience
Reconstitution of enzymatic activity from fragments of M1 RNA.
1992
Localization in the Nucleolus and Coiled Bodies of Protein Subunits of the Ribonucleoprotein Ribonuclease P
1999
Cleavage of tRNA precursors by the RNA subunit of E. coli ribonuclease P (M1 RNA) is influenced by 3′-proximal CCA in the substrates
1984 Standout
Ribonuclease P. Postscript
1990
Tyrosine tRNA Precursor Molecule Polynucleotide Sequence
1971 Standout
Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells.
1989 Standout
M1 RNA with large terminal deletions retains its catalytic activity
1986 Standout
E. coli RNAase P has a required RNA component in vivo
1980 Standout
Specific Interactions in RNA Enzyme-Substrate Complexes
1989 StandoutScience
Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P
1997
An immunological determinant of RNase P protein is conserved between Escherichia coli and humans.
1989 Standout
Heterologous enzyme function in Escherichia coli and the selection of genes encoding the catalytic RNA subunit of RNase P.
1987 Standout
A specific endoribonuclease, RNase P, affects gene expression of polycistronic operon mRNAs
2003
Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli.
1991
Aspects of biochemical catalysis
1984 Standout
Enzymatic cleavage of RNA by RNA
1986 Standout
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
1983 Standout
Kinetics and intermediates in the intracellular synthesis of bacteriophage T4 deoxyribonucleic acid
1970 Standout
A trinucleotide can promote metal ion-dependent specific cleavage of RNA.
1992
Characterization of an RNase P activity from HeLa cell mitochondria. Comparison with the cytosol RNase P activity.
1985 Standout
Recent studies of ribonuclease P.
1993
Three-dimensional working model of M1 RNA, the catalytic RNA subunit of ribonuclease P from Escherichia coli.
1994
Catalytic Activity of an RNA Molecule Prepared by Transcription in Vitro
1984 StandoutScience
Purification and Properties of a Specific Escherichia coli Ribonuclease which Cleaves a Tyrosine Transfer Ribonucleic Acid Precursor
1972 Standout
Model Substrates for an RNA Enzyme
1987 StandoutScience
Identification of tRNA Precursor Molecules made by Phage T4
1973 Standout
Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli
1986 Standout
Reconstitution of RNAase P activity using inactive subunits from E. coli and HeLa cells
1986 Standout
Reconstitution of RNase P activity from inactive RNA and protein.
1979 Standout
Antibodies in human serum that precipitate ribonuclease P.
1988 Standout
Nucleotide sequence of the gene encoding the RNA subunit (M1 RNA) of ribonuclease P from Escherichia coli
1982 Standout
Structure in solution of M1 RNA, the catalytic subunit of ribonuclease P from Escherichia coli
1984 Standout
The protein cofactor allows the sequence of an RNase P ribozyme to diversify by maintaining the catalytically active structure of the enzyme.
1997