Citation Impact
Citing Papers
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
2007 Standout
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
2007 Standout
Crystal Structures of the Adenylate Sensor from Fission Yeast AMP-Activated Protein Kinase
2007 Science
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases
2003
TOR Signaling in Growth and Metabolism
2006 Standout
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
Identifying positive selection candidate loci for high-altitude adaptation in Andean populations
2009
A Conserved Sequence Immediately N-terminal to the Bateman Domains in AMP-activated Protein Kinase γ Subunits Is Required for the Interaction with the β Subunits
2007
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells
2007
Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR
2004
AMP-activated protein kinase: also regulated by ADP?
2011
Molecular mediators of hepatic steatosis and liver injury
2004 Standout
Identification of novel single amino acid changes that result in hyperactivation of the unique GTPase, Rheb, in fission yeast
2005
Abiotic Stress Signaling and Responses in Plants
2016 Standout
Structure of the BamC Two-Domain Protein Obtained by Rosetta with a Limited NMR Data Set
2011 StandoutNobel
A Novel Domain in AMP-Activated Protein Kinase Causes Glycogen Storage Bodies Similar to Those Seen in Hereditary Cardiac Arrhythmias
2003
AMPK at the crossroads of circadian clocks and metabolism
2012
mTOR Signaling in Growth Control and Disease
2012 Standout
The Tuberous Sclerosis Complex
2006 Standout
Liver Regeneration
2006
AMP-activated protein kinase and human cancer: cancer metabolism revisited
2008
A Revised Model for AMP-activated Protein Kinase Structure
2006
SNF1/AMPK/SnRK1 kinases, global regulators at the heart of energy control?
2006
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Biochemical Regulation of Mammalian AMP-activated Protein Kinase Activity by NAD and NADH
2004
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
2005 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
2006
New roles for the LKB1→AMPK pathway
2005
Mammalian TAK1 Activates Snf1 Protein Kinase in Yeast and Phosphorylates AMP-activated Protein Kinase in Vitro
2006
The Failing Heart — An Engine Out of Fuel
2007 Standout
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
2009 Standout
The 5′-AMP-activated Protein Kinase γ3 Isoform Has a Key Role in Carbohydrate and Lipid Metabolism in Glycolytic Skeletal Muscle
2004
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
2005
Structure and function of AMP‐activated protein kinase
2009
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
AMP‐activated protein kinase and cancer
2009
AMP-activated Protein Kinase β Subunit Tethers α and γ Subunits via Its C-terminal Sequence (186–270)
2005
Dissecting the Role of 5′-AMP for Allosteric Stimulation, Activation, and Deactivation of AMP-activated Protein Kinase
2006
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1
2005
Metformin increases the PGC-1α protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo
2006
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
2004
AMP-activated protein kinase: nature's energy sensor
2011
Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase
2005
Insulin sensitivity: modulation by nutrients and inflammation
2008
Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase
2005
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase
2005
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Mitochondria: In Sickness and in Health
2012 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
AMP‐activated protein kinase phosphorylates glutamine : fructose‐6‐phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity
2009
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue
2005
Regulation of cancer cell metabolism
2011 Standout
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Phosphorylation and Functional Inactivation of TSC2 by Erk
2005 Standout
AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs
2015
Intrasteric control of AMPK via the γ1 subunit AMP allosteric regulatory site
2003
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle
2006
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Structural Insight into AMPK Regulation: ADP Comes into Play
2007
AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise
2004
AMPK activation: a therapeutic target for type 2 diabetes?
2014
A pancreatic islet-specific microRNA regulates insulin secretion
2004 StandoutNature
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome
2004
Structural basis of AMPK regulation by small molecule activators
2013
The role of site accessibility in microRNA target recognition
2007 Standout
AMPK functions as an adenylate charge-regulated protein kinase
2012
Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1
2007 Nature
Conserved α-Helix Acts as Autoinhibitory Sequence in AMP-activated Protein Kinase α Subunits
2006
AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells
2004
Drosophila lacking microRNA miR-278 are defective in energy homeostasis
2006
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance
2008
The LKB1 tumor suppressor negatively regulates mTOR signaling
2004
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway
2006
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Bateman domains and adenosine derivatives form a binding contract
2004
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin
2004
The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases
2005
Glycogen debranching enzyme association with β-subunit regulates AMP-activated protein kinase activity
2005
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
AMPK and PPARδ Agonists Are Exercise Mimetics
2008
Genetic causes of human heart failure
2005
Structure of a CBS-domain pair from the regulatory γ1 subunit of human AMPK in complex with AMP and ZMP
2007
5′-AMP-activated Protein Kinase Controls Insulin-containing Secretory Vesicle Dynamics
2003
Adenosine Monophosphate-Activated Protein Kinase: A Central Regulator of Metabolism with Roles in Diabetes, Cancer, and Viral Infection
2011
Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes
2004 StandoutNobel
AMP‐activated protein kinase – development of the energy sensor concept
2006
Function of Mammalian LKB1 and Ca2+/Calmodulin-dependent Protein Kinase Kinase α as Snf1-activating Kinases in Yeast
2005
Predominant α2/β2/γ3 AMPK activation during exercise in human skeletal muscle
2006
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling
2007
Minireview: The AMP-Activated Protein Kinase Cascade: The Key Sensor of Cellular Energy Status
2003
The α2–5′AMP-Activated Protein Kinase Is a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and Is Responsive to Glucose Loading
2004
AMP-Activated Protein Kinase in the Heart
2007
Bateman domains and adenosine derivatives form a binding contract
2004
Type 2 diabetes: principles of pathogenesis and therapy
2005 Standout
AMP-Activated Protein Kinase as a Drug Target
2006
2016
The AMP-activated protein kinase cascade – a unifying system for energy control
2003
AMP-activated protein kinase and the metabolic syndrome
2005
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver
2004
The AMP-activated protein kinase pathway – new players upstream and downstream
2004
Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis
2003
Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)
2014
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
Interleukin-6 Regulation of AMP-Activated Protein Kinase
2006
Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms
2015
Molecular mediators of hepatic steatosis and liver injury
2004 Standout
AMPK: A Key Sensor of Fuel and Energy Status in Skeletal Muscle
2006
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
2012
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Works of Sid Murthy being referenced
AMP-Activated Protein Kinase Is Not Down-Regulated in Human Skeletal Muscle of Obese Females
2004
Recent advances in the regulation of the TOR pathway by insulin and nutrients
2004
AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen
2003
Effect of Exercise Intensity on Skeletal Muscle AMPK Signaling in Humans
2003
AMP-activated protein kinase, super metabolic regulator
2003