Standout Papers
Citation Impact
Citing Papers
Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease
2014
Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance
2014 StandoutNobel
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Abolition of Long-Term Stability of New Hippocampal Place Cell Maps by NMDA Receptor Blockade
1998 StandoutScienceNobel
Low clinical diagnostic accuracy of early vs advanced Parkinson disease
2014
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
The odor stick identification test for Japanese differentiates Parkinson's disease from multiple system atrophy and progressive supra nuclear palsy
2011
The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia
2010
Alterations in glutamate but not GABAA receptor subunit expression as a consequence of epileptiform activity in vitro
1995
Progression of parkinsonism in multiple system atrophy
2005
Neurophysiological characterization of parkinsonian syndromes
2000
Molecular cloning and characterization of the rat NMDA receptor
1991 StandoutNature
T1ρ and T2ρ MRI in the evaluation of Parkinson’s disease
2010
Apoptosis in the nervous system
2000 StandoutNature
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
Biomarkers to detect central dopamine deficiency and distinguish Parkinson disease from multiple system atrophy
2008
5′ Splice Site Mutations in tau Associated with the Inherited Dementia FTDP-17 Affect a Stem-Loop Structure That Regulates Alternative Splicing of Exon 10
1999
Head injury, alpha‐synuclein Rep1, and Parkinson's disease
2011
Montreal Cognitive Assessment Performance in Patients with Parkinson's Disease with “Normal” Global Cognition According to Mini‐Mental State Examination Score
2008
A novel presenilin 1 mutation associated with Pick's disease but not β‐amyloid plaques
2004
FTDP-17: An early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation
1999
Microstructure of a spatial map in the entorhinal cortex
2005 StandoutNatureNobel
Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
2012 Standout
Tau protein pathology in neurodegenerative diseases
1998
A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy
1999
Activity-dependent scaling of quantal amplitude in neocortical neurons
1998 StandoutNature
Phenotypic variation in hereditary frontotemporal dementia with tau mutations
1999
Parkinson's disease: clinical features and diagnosis
2008 Standout
Hallucinations in Parkinson's disease: Prevalence, phenomenology and risk factors
2000 Standout
Clinical diagnosis of multiple system atrophy: level of agreement between Quinn's criteria and the consensus conference guidelines
2001
Staging of brain pathology related to sporadic Parkinson’s disease
2002 Standout
Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17: A New Group of Tauopathies
1998
Clinical correlates of selective pathology in the amygdala of patients with Parkinson’s disease
2002
Alpha-synuclein and transgenic mouse models
2004
Cardiac MIBG scintigraphy is a sensitive tool for detecting cardiac sympathetic denervation in Parkinson's disease
2003
A Hundred Years of Alzheimer's Disease Research
2006
Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17
1998
Stable Expression in Chinese Hamster Ovary Cells of Mutated Tau Genes Causing Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17)
1999
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria
2007 Standout
Brain Glucose Metabolism in Postanoxic Syndrome
1990
Dementia of Frontal Type and Dementias with Subcortical Gliosis
1998
The frequency and significance of ‘striatal toe’ in parkinsonism
2002
Erectile and urinary dysfunction may be the presenting features in patients with multiple system atrophy: a retrospective study
2003
Multiple system atrophy. Clinical and MR observations on 42 cases
1993
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
2009
Mutation-dependent aggregation of tau protein and its selective depletion from the soluble fraction in brain of P301L FTDP-17 patients
2000
Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations
2003
Parkinsonism and Neck Extensor Myopathy
2001
What Is the Accuracy of the Clinical Diagnosis of Multiple System Atrophy?
1997
Comparison of diffusion‐weighted imaging and [123I]IBZM‐SPECT for the differentiation of patients with the Parkinson variant of multiple system atrophy from those with Parkinson's disease
2004
Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval
2002
Characteristics of the Dysarthria of Multiple System Atrophy
1996
Decoupling the Cortical Power Spectrum Reveals Real-Time Representation of Individual Finger Movements in Humans
2009
Frontotemporal dementia: Clinicopathological correlations
2006
Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau
1998
Abnormal microtubule packing in processes of SF9 cells expressing the FTDP‐17 V337M tau mutation
1999
Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: electrophysiological data
1990
Apparent diffusion coefficient measurements of the middle cerebellar peduncle differentiate the Parkinson variant of MSA from Parkinson's disease and progressive supranuclear palsy
2006
Identifying prodromal Parkinson's disease: Pre‐Motor disorders in Parkinson's disease
2012
Machado-Joseph Disease: from first descriptions to new perspectives
2011
Long-term stability of the place-field activity of single units recorded from the dorsal hippocampus of freely behaving rats
1990
Fragile X‐associated tremor/ataxia syndrome: Clinical features, genetics, and testing guidelines
2007
Parkinson's disease
2015 Standout
Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia
2001
Joint and skeletal deformities in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy
2006
Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism
2006
Parkinson’s disease: the thalamic components of the limbic loop are severely impaired by α-synuclein immunopositive inclusion body pathology
2002
Thiocyanate stabilizes AMPA binding to the quisqualate receptor
1988
SIC Task Force appraisal of clinical diagnostic criteria for parkinsonian disorders
2003
Impaired response of human motoneurones to corticospinal stimulation after voluntary exercise
1999
Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy
2007
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Correlation between cardiac 123I‐MIBG and odor identification in patients with Parkinson's disease and multiple system atrophy
2006
Immunohistochemical and Biochemical Studies Demonstrate a Distinct Profile of α-Synuclein Permutations in Multiple System Atrophy
2000
Parkinson's disease: a dual‐hit hypothesis
2007
Pick's Disease: A Modern Approach
1998
Where Does Parkinson Disease Pathology Begin in the Brain?
2002
The effect of Alzheimer's disease and Parkinson's disease on olfaction: A meta-analysis
2012
A new case of frontotemporal dementia and parkinsonism resulting from an intron 10 +3‐splice site mutation in the tau gene: clinical and pathological features
2000
The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service
2002
Pain and motor complications in Parkinson's disease
2006
Axonal Transection in the Lesions of Multiple Sclerosis
1998 Standout
Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease
2003
Sporadic adult onset ataxia of unknown etiology
2007
Delayed emergence of a parkinsonian disorder or dementia in 81% of older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: a 16-year update on a previously reported series
2013
Alzheimer's Disease
2010 Standout
Tau gene mutation in familial progressive subcortical gliosis
1999
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
GABAergic Mechanisms in Epilepsy
2001
Using gadolinium‐enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis
1992
High Prevalence of Mutations in the Microtubule-Associated Protein Tau in a Population Study of Frontotemporal Dementia in the Netherlands
1999
Are Ubiquitination Pathways Central to Parkinson's Disease?
2003
Frontotemporal lobar degeneration and ubiquitin immunohistochemistry
2004
Functional imaging with positron emission tomography in multiple system atrophy
2005
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
A clinical pathological comparison of three families with frontotemporal dementia and identical mutations in the tau gene (P301L)
1999
From genotype to phenotype: A clinical, pathological, and biochemical investigation of frontotemporal dementia and parkinsonism (FTDP-17) caused by the P301L tau mutation
1999
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.
2000 Standout
The Human Hippocampus and Spatial and Episodic Memory
2002 StandoutNobel
Segregation of a Missense Mutation in the Microtubule-Associated Protein Tau Gene with Familial Frontotemporal Dementia and Parkinsonism
1998
Positron Emission Tomography Diagnosis of Alzheimer's Disease
2005
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
Parkinson's Disease and Parkinsonism: Neuropathology
2012
Reduced genital sensitivity in female patients with multiple system atrophy of parkinsonian type
2002
Progression of putaminal degeneration in multiple system atrophy: A serial diffusion MR study
2006
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
Head direction cells and the neurophysiological basis for a sense of direction
1998
Some highlights of research on the effects of caudate nucleus lesions over the past 200 years
2008
Tau Pathology in Two Dutch Families with Mutations in the Microtubule-Binding Region of Tau
1998
Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors
2008
Solvent exposures and parkinson disease risk in twins
2011
The diagnosis of Parkinson's disease
2005
Familial multiple system tauopathy with presenile dementia: A disease with abundant neuronal and glial tau filaments
1997
Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
2009
The Basal Ganglia and Chunking of Action Repertoires
1998
The Evolution of Diagnosis in Early Parkinson Disease
2000
Frequency oftau mutations in three series of non-Alzheimer's degenerative dementia
1999
Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
2010
The -synuclein gene in multiple system atrophy
2006
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Multiple system atrophy in a patient with the spinocerebellar ataxia 3 gene mutation
2006
Multiplex Families With Multiple System Atrophy
2007
Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease
2010
Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene
2000
Striatal D2 receptor status in patients with Parkinson's disease, striatonigral degeneration, and progressive supranuclear palsy, measured with 11C‐raclopride and positron emission tomography
1992
The preparation, execution and suppression of copied movements in the human brain
1998
Tau is a candidate gene for chromosome 17 frontotemporal dementia
1998
Familial frontotemporal dementia with a P301L tau mutation in Japan
2000
Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene
1994
Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors
1990
Neurodegenerative Tauopathies
2001 Standout
Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct
1996 StandoutScience
Skin nerve α-synuclein deposits
2014
Editorial Expression of Concern for multiple articles
2008 StandoutNobel
Improved accuracy of clinical diagnosis of Lewy body Parkinson’s disease
2001
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease
2009 Standout
A Century of Alzheimer's Disease
2006 StandoutScience
Camptocormia
2005
Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene
2000
γ‐Aminobutyric Acid and Benzodiazepine Receptor Changes Induced by Unilateral 6‐Hydroxydopamine Lesions of the Medial Forebrain Bundle
1985
Effect of contraction strength on responses in biceps brachii and adductor pollicis to transcranial magnetic stimulation
1997
Advances in Treatment of Wilson Disease
2017
Parkinson disease and smoking revisited
2014
Cognitive impairment in incident, untreated Parkinson disease
2008
MDS clinical diagnostic criteria for Parkinson's disease
2015 Standout
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Synaptic Control of Motoneuronal Excitability
2000
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Cortical Mechanisms of Human Imitation
1999 StandoutScience
Reversal of Experimental Parkinsonism by Lesions of the Subthalamic Nucleus
1990 StandoutScience
Muscle activation in unilateral and bilateral efforts assessed by motor nerve and cortical stimulation
1996
Spinal and Supraspinal Factors in Human Muscle Fatigue
2001 Standout
Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements
1999
From genetics to pathology: tau and a–synuclein assemblies in neurodegenerative diseases
2001
A default mode of brain function
2001 Standout
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
1998 Nobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Exploring the relationship between essential tremor and Parkinson's disease
2006
Bimanual coordination in monkeys
1968 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Pick's disease is associated with mutations in thetau gene
2000
Do published criteria improve clinical diagnostic accuracy in multiple system atrophy?
2002
MRI of the human brain at 130 microtesla
2013 StandoutNobel
Conjunctive Representation of Position, Direction, and Velocity in Entorhinal Cortex
2006 StandoutScienceNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Reduced cardiac uptake and enhanced washout of 123I-MIBG in pure autonomic failure occurs conjointly with Parkinson's disease and dementia with Lewy bodies.
2006
Rapid metabolic evolution in human prefrontal cortex
2011 StandoutNobel
The overlap of amyotrophic lateral sclerosis and frontotemporal dementia
2002
The Metabolic Substrates of Bradykinesia and Tremor in Uncomplicated Parkinson's Disease
2002
ALZHEIMER'S DISEASE: Genetic Studies and Transgenic Models
1998
Neurophysiological correlates of hand preference in primary motor cortex of adult squirrel monkeys
1992
Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD
2005
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
1990 StandoutScience
Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
1998
Cognitive profile of patients with newly diagnosed Parkinson disease
2005
Second consensus statement on the diagnosis of multiple system atrophy
2008 Standout
Clinical Implications of Cardiac-MIBG SPECT in the Differentiation of Parkinsonian Syndromes
2006
A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration
1999
Ia afferent activity during a variety of voluntary movements in the cat
1977
Aberrant Splicing of tau Pre-mRNA Caused by Intronic Mutations Associated with the Inherited Dementia Frontotemporal Dementia with Parkinsonism Linked to Chromosome 17
2000
How common are the “common” neurologic disorders?
2007
Molecular Diversity of Glutamate Receptors and Implications for Brain Function
1992 StandoutScience
Works of Sid Gilman being referenced
Inhibitory and excitatory amino acid neurotransmitter binding sites in cynomolgus monkey (Macaca fascicularis) cervical spinal cord
1993
Autoradiographic localization of inhibitory and excitatory amino acid neurotransmitter receptors in human normal and olivopontocerebellar atrophy cerebellar cortex
1990
Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex
1990
The Spinocerebellar Ataxias
2000
Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)
2004
Feline subthalamic nucleus neurons contain glutamate-like but not GABA-like or glycine-like immunoreactivity
1989
Differentiation of Alzheimer's disease from dementia with Lewy bodies utilizing positron emission tomography with [18F]fluorodeoxyglucose and neuropsychological testing
2004
Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions
1996
Cerebral hypometabolism in progressive supranuclear palsy studied with positron emission tomography
1988
Decreased striatal monoaminergic terminals in olivopontocerebellar atrophy and multiple system atrophy demonstrated with positron emission tomography
1996
Diagnostic Criteria for Parkinson Disease
1999 Standout
Patterns of cerebral glucose metabolism detected with positron emission tomography differ in multiple system atrophy and olivopontocerebellar atrophy
1994
Consensus statement on the diagnosis of multiple system atrophy
1998
Unilateral striatal lesions in the cat disrupt well-learned motor plans in a GO/NO-GO reaching task
1997
Cerebellar and brainstem hypometabolism in olivopontocerebellar atrophy detected with positron emission tomography
1988
Decreased striatal monoaminergic terminals in multiple system atrophy detected with positron emission tomography
1999
Altered excitatory and inhibitory amino acid receptor binding in hippocampus of patients with temporal lobe epilepsy
1991
Speech disorders in olivopontocerebellar atrophy correlate with positron emission tomography findings
1988
Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference
1997
Primate basal ganglia activity in a precued reaching task: preparation for movement
1993
Cortical blindness: Etiology, diagnosis, and prognosis
1987
Perceptual analysis of speech disorders in progressive supranuclear palsy
1993
The initial diagnosis of multiple sclerosis: Clinical impact of magnetic resonance imaging
1985
Denny–Brown, Wilson’s disease, and BAL (British antilewisite [2,3-dimercaptopropanol])
2002
11C-DTBZ and 18F-FDG PET measures in differentiating dementias.
2005
Descending vestibular activity and its modulation by proprioceptive, cerebellar, and reticular influences
1959
Diagnostic criteria for dementia in clinical trials. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines.
1997
Characterization of spontaneous unit activity in hypothalamus and reticular formation recorded with semimicroelectrodes
1973
Corticospinal Neurones. Their Role in Movement
1979
Brain stem pathways for vestibular projections to cerebral cortex in the cat
1977
DISORDERS OF MOVEMENT AND BEHAVIOUR FOLLOWING DORSAL COLUMN LESIONS
1966
A densitometer for quantitative autoradiography
1983
PET measurement of cardiac and nigrostriatal denervation in Parkinsonian syndromes.
2006