Standout Papers
Citation Impact
Citing Papers
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules
2003
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
The Respiratory Burst Oxidase
1992
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the U.S. Registry
2014 Standout
Defibrotide reduces procoagulant activity and increases fibrinolytic properties of endothelial cells
2003
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
1994 Standout
Increasingly frequent diagnosis of acute gastrointestinal graft-versus-host disease after allogeneic hematopoietic cell transplantation
2004
Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer
2004
Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes
2006
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
2007
Oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction
2015
Defibrotide for the treatment of hepatic veno-occlusive disease: results of the European compassionate-use study
2000
Nucleotide signalling during inflammation
2014 StandoutNature
Hematologic and Cytogenetic Responses to Imatinib Mesylate in Chronic Myelogenous Leukemia
2002 Standout
Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome
2002
Veno-occlusive disease of the liver after allogeneic bone marrow transplantation in children with hematologic malignancies: incidence, onset time and risk factors
1998
Hydrogen peroxide mediates amyloid β protein toxicity
1994 Standout
MGMT Methylation Status: The Advent of Stratified Therapy in Glioblastoma?
2007
Hypermethylation of the DNA Repair Gene O6-Methylguanine DNA Methyltransferase and Survival of Patients With Diffuse Large B-Cell Lymphoma
2002
Acute graft-vs-host disease
2001
Can Only Partial T-Cell Depletion of the Graft before Hematopoietic Stem Cell Transplantation Mitigate Graft-versus-Host Disease While Preserving a Graft-versus-Leukemia Reaction? A Prospective Phase II Study
2006
Inactivation of the DNA-Repair GeneMGMTand the Clinical Response of Gliomas to Alkylating Agents
2000 Standout
Hypoxia and Inflammation
2011 Standout
Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia
2001 Standout
Tissue Destruction by Neutrophils
1989 Standout
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
Regulation and termination of NADPH oxidase activity
2005
Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs oral busulfan in adults conditioned with busulfan + cyclophosphamide for allogeneic bone marrow transplantation
2004
Venoocclusive disease of the liver: development of a model for predicting fatal outcome after marrow transplantation.
1993
A Prospective, Randomized Trial of Autologous Bone Marrow Transplantation and Chemotherapy in Multiple Myeloma
1996 Standout
Multi-institutional Feasibility Study of a Fast Patient Localization Method in Total Marrow Irradiation With Helical Tomotherapy: A Global Health Initiative by the International Consortium of Total Marrow Irradiation
2014
Graft-versus-host disease and the Th1/Th2 paradigm
1996
Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas
2004
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
1993 Standout
Vascular disorders of the liver # †
2008 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Epigenetics in Cancer
2008 Standout
Veno-occlusive disease of the liver after busulfan, melphalan, and thiotepa conditioning therapy: Incidence, risk factors, and outcome
1999
Alkylation damage in DNA and RNA—repair mechanisms and medical significance
2004
Prevention of veno-occlusive disease with defibrotide after allogeneic stem cell transplantation
2004
Outcomes among 562 Recipients of Placental-Blood Transplants from Unrelated Donors
1998 Standout
Graft-versus-host disease
2009 Standout
Can graft-versus-leukemia reactivity be dissociated from graft-versus-host disease?
2007
Nox proteins in signal transduction
2009
Myeloperoxidase: a key regulator of neutrophil oxidant production
1997
Malignant Gliomas in Adults
2008 Standout
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation
2010 Standout
OPTIONS FOR THERAPY IN CHRONIC MYELOID LEUKAEMIA
1995
Pathophysiology of Graft-Versus-Host Disease
2006
Hematopoietic Stem-Cell Transplantation
2006 Standout
Enzymic mechanisms of superoxide production
1991
Hypoxia and Metabolic Factors That Influence Inflammatory Bowel Disease Pathogenesis
2011
Intravenous versus oral busulfan as part of a busulfan/cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: Decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality
2002
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
2001 Standout
Analysis of 462 Transplantations from Unrelated Donors Facilitated by the National Marrow Donor Program
1993
Transplantation of Anergic Histoincompatible Bone Marrow Allografts
1999
Immunobiology of acute graft-versus-host disease
2003
Bone Marrow Transplantation
1994
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
1997 Standout
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
2005 Standout
Idarucizumab for Dabigatran Reversal
2015 Standout
Treatment of High-Risk Acute Leukemia with T-Cell–Depleted Stem Cells from Related Donors with One Fully Mismatched HLA Haplotype
1998
Hepatic Venoocclusive Disease in Blood and Bone Marrow Transplantation in Children and Young Adults: Incidence, Risk Factors, and Outcome in a Cohort of 241 Patients
2002
The Japanese multicenter open randomized trial of ursodeoxycholic acid prophylaxis for hepatic veno-occlusive disease after stem cell transplantation
2000
A review of autologous hematopoietic cell transplantation
2000 Nobel
Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: Myeloablation with reduced toxicity
2003
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
Repair of O6-alkylguanine by alkyltransferases
2000
Prognostic value of doppler-ultrasonography in hepatic veno-occlusive disease
2002
Transjugular Intrahepatic Portosystemic Shunt for the Management of Severe Venoocclusive Disease Following Bone Marrow Transplantation
1996
Use of prophylactic anticoagulation and the risk of hepatic veno-occlusive disease in patients undergoing hematopoietic stem cell transplantation: a systematic review and meta-analysis
2006
A randomized trial of heparin plus ursodiol vs heparin alone to prevent hepatic veno-occlusive disease after hematopoietic stem cell transplantation
2002
Brain Tumors
2001 Standout
Symptoms and Suffering at the End of Life in Children with Cancer
2000 Standout
Hypoxia: an alarm signal during intestinal inflammation
2010
MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
2005 Standout
Total Body Irradiation and Acute Graft-Versus-Host Disease: The Role of Gastrointestinal Damage and Inflammatory Cytokines
1997
Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation
2003
Myeloperoxidase-dependent effect of amines on functions of isolated neutrophils.
1983
Hepatic injury after nonmyeloablative conditioning followed by allogeneic hematopoietic cell transplantation: a study of 193 patients
2003
Voltage-Gated Proton Channels and Other Proton Transfer Pathways
2003
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
1999 StandoutScience
Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery
2011
A Risk Score for Mortality after Allogeneic Hematopoietic Cell Transplantation
2006
Acute Myeloid Leukemia
2015 Standout
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities
2004
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Cell Surface Antigen and Molecular Targeting in the Treatment of Hematologic Malignancies
2002
Generation of nitrogen-chlorine oxidants by human phagocytes.
1984
Treatment of Hepatic Venocclusive Disease With Recombinant Human Tissue Plasminogen Activator and Heparin in 42 Marrow Transplant Patients
1997
Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide
2004
The hemochromatosis C282Y allele: a risk factor for hepatic veno-occlusive disease after hematopoietic stem cell transplantation
2005
Augmentation of umbilical cord blood (UCB) transplantation with ex vivo–expanded UCB cells: results of a phase 1 trial using the AastromReplicell System
2003
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
VENO-OCCLUSIVE DISEASE OF THE LIVER
1955
Phase II Trial of Temozolomide Plus O6-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma
2009
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
TREATMENT OF HEPATIC VENOOCCLUSIVE DISEASE WITH RECOMBINANT HUMAN TISSUE PLAMINOGEN ACTIVATOR OR ORTHOTOPIC LIVER TRANSPLANTATION AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION1
1996
Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells
2003
Conditioning regimens for hematopoietic cell transplantation: one size does not fit all
2014
Unrelated donor marrow transplantation in children
1995
Embolization by sinusoidal lining cells obstructs the microcirculation in rat sinusoidal obstruction syndrome
2003
Promoter Hypermethylation of the DNA Repair Gene O6‐Methylguanine‐DNA Methyltransferase is an Independent Predictor of Shortened Progression Free Survival in Patients with Low‐grade Diffuse Astrocytomas
2003
An evidence-based analysis of the effect of busulfan, hydroxyurea, interferon, and allogeneic bone marrow transplantation in treating the chronic phase of chronic myeloid leukemia: developed for the American Society of Hematology.
1999
Phase I Study of 131I-Anti-CD45 Antibody Plus Cyclophosphamide and Total Body Irradiation for Advanced Acute Leukemia and Myelodysplastic Syndrome
1999
The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation
2000
Chemoradiotherapy in Malignant Glioma: Standard of Care and Future Directions
2007
Treatment of the Newly Diagnosed Adult with De Noyo Acute Myeloid Leukemia
1993
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Ursodiol Prophylaxis against Hepatic Complications of Allogeneic Bone Marrow Transplantation
1998
Morbidity and mortality with nonmyeloablative compared with myeloablative conditioning before hematopoietic cell transplantation from HLA-matched related donors
2004
Cytokine dysregulation and acute graft-versus-host disease
1992
Defibrotide for the treatment of hepatic veno‐occlusive disease: results of the European compassionate‐use study
2000
Immunobiology of acute graft-versus-host disease.
1987
Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants
2002 StandoutScience
Metal–Organic Frameworks in Biomedicine
2011 Standout
Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation
2002
GITR Activation Induces an Opposite Effect on Alloreactive CD4+ and CD8+ T Cells in Graft-Versus-Host Disease
2004 StandoutNobel
Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation
2004
Treatment of severe veno-occlusive disease with defibrotide: compassionate use results in response without significant toxicity in a high-risk population.
1998
Human DNA Repair Genes
2001 StandoutScienceNobel
A controlled trial of recombinant human granulocyte-macrophage colony- stimulating factor after total body irradiation, high-dose chemotherapy, and autologous bone marrow transplantation for acute lymphoblastic leukemia or malignant lymphoma
1992
A randomized controlled trial of pentoxifylline for the prevention of regimen-related toxicities in patients undergoing allogeneic marrow transplantation
1993
Norethisterone Treatment, a Major Risk-Factor for Veno-Occlusive Disease in the Liver After Allogeneic Bone Marrow Transplantation
1998
Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity
2008
Superoxide-dependent oxidation of extracellular reducing agents by isolated neutrophils.
1988
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury
1988
Proton-Coupled Electron Transfer
2012 Standout
Nitric oxide: an endogenous modulator of leukocyte adhesion.
1991 Standout
Defibrotide in the treatment of children with veno-occlusive disease (VOD): a retrospective multicentre study demonstrates therapeutic efficacy upon early intervention
2003
Treatment of the newly diagnosed adult with de novo acute myeloid leukemia.
1993
Monocyte and granulocyte-mediated tumor cell destruction. A role for the hydrogen peroxide-myeloperoxidase-chloride system.
1982
Works of SI Bearman being referenced
Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study.
1998
Regimen-related toxicity and early posttransplant survival in patients undergoing marrow transplantation for lymphoma.
1989 StandoutNobel
Avoiding hepatic veno-occlusive disease: what do we know and where are we going?
2001
Transplantation of adult and pediatric cancer patients with ex vivo expanded cord blood
2000
Effects of oxygen tension and pH on the respiratory burst of human neutrophils
1979
Effects of oxygen tension and pH on the respiratory burst of human neutrophils
1979
Naturally occurring anticoagulants and bone marrow transplantation: plasma protein C predicts the development of venocclusive disease of the liver
1993
Amifostine (WR-2721) shortens the engraftment period of 4- hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support
1994
Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens
1991
The syndrome of hepatic veno-occlusive disease after marrow transplantation
1995
Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens
1991
Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]
1990
Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]
1990
Recombinant human tissue plasminogen activator for the treatment of established severe venocclusive disease of the liver after bone marrow transplantation
1992
Comparison of morbidity and mortality after marrow transplantation from HLA-genotypically identical siblings and HLA-phenotypically identical unrelated donors.
1994