Shuo-Bin Chen

c-di-GMP can form remarkably stable G-quadruplexes at physiological conditions in the presence of some planar intercalators

Molecular dynamics simulations of G-DNA and perspectives on the simulation of nucleic acid structures

Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

PROTAC targeted protein degraders: the past is prologue

The application of DNA and RNA G-quadruplexes to therapeutic medicines

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies

The Hitchhiker’s Guide to Flow Chemistry

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

Artificial Molecular Machines

Rapid Development and Scale-Up of a 1H-4-Substituted Imidazole Intermediate Enabled by Chemistry in Continuous Plug Flow Reactors

Reactive Oxygen Species (ROS)-Based Nanomedicine

A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology

Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA

Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand

Design, synthesis, and biological evaluation of 2-arylethenylquinoline derivatives as multifunctional agents for the treatment of Alzheimer's disease

New Insights into the Structures of Ligand−Quadruplex Complexes from Molecular Dynamics Simulations