Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
2009 StandoutScience
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis
2019
A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation
2015 Science
Normal gut microbiota modulates brain development and behavior
2011 Standout
Cutting Edge: Developmental Stage-Specific Recruitment of Cohesin to CTCF Sites throughout Immunoglobulin Loci during B Lymphocyte Development
2009
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
2013 Standout
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus
2009 Nature
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
2010 Standout
The molecular hallmarks of epigenetic control
2016 Standout
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Association of Patient Social, Cognitive, and Functional Risk Factors with Preventable Hospitalizations: Implications for Physician Value-Based Payment
2019
Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods?
2013
Inflammation and metabolic disorders
2006 StandoutNature
Central nervous system control of food intake and body weight
2006 StandoutNature
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Use of a hanging-weight system for isolated renal artery occlusion during ischemic preconditioning in mice
2006
Thoughts for Food: Brain Mechanisms and Peripheral Energy Balance
2006
The Human Intestinal Microbiome in Health and Disease
2016 Standout
Lipid phosphatases as drug discovery targets for type 2 diabetes
2006
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth
2015
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Metabolic and Hormonal Changes After Laparoscopic Roux-en-Y Gastric Bypass and Sleeve Gastrectomy: a Randomized, Prospective Trial
2012
Maternal and child undernutrition and overweight in low-income and middle-income countries
2013 Standout
DNA methylation: roles in mammalian development
2013 Standout
Inflammation, stress, and diabetes
2005 Standout
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
PRC2 mediated H3K27 methylations in cellular identity and cancer
2015
Molecular signaling involved in regulating feeding and other mitivated behaviors
2007
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Ghrelin induces adiposity in rodents
2000 StandoutNature
Central nervous system control of food intake
2000 StandoutNature
High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the adipose tissue, along with increased expression of extracellular matrix remodelling- and inflammation-related genes
2015
Mass-spectrometric exploration of proteome structure and function
2016 Nature
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
2008
The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene
1999 Standout
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
2004
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
2012
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Driver mutations of cancer epigenomes
2014
A Neural Circuit Mechanism Integrating Motivational State with Memory Expression in Drosophila
2009
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
2016
NPY receptors as potential targets for anti‐obesity drug development
2011
Childhood obesity
2010
What We Talk About When We Talk About Fat
2014 Standout
Activation of Arcuate Nucleus Neurons by Systemic Administration of Leptin and Growth Hormone-Releasing Peptide-6 in Normal and Fasted Rats
1999
Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight
1999
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Epigenetic Determinants of Cancer
2016
Topological domains in mammalian genomes identified by analysis of chromatin interactions
2012 StandoutNature
Obesity is associated with macrophage accumulation in adipose tissue
2003 Standout
Comprehensive Integration of Single-Cell Data
2019 Standout
The H19 locus: Role of an imprinted non‐coding RNA in growth and development
2010
The neurochemical characterisation of hypothalamic pathways projecting polysynaptically to brown adipose tissue in the rat
2002
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet
2017 Standout
Enhancer function: new insights into the regulation of tissue-specific gene expression
2011
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians
2008
CTCF: Master Weaver of the Genome
2009 Standout
CLOCK:BMAL1 is a pioneer-like transcription factor
2014 StandoutNobel
The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome
2012
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
CRISPR/Cas9-Mediated Genome Editing of Epigenetic Factors for Cancer Therapy
2015
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight*
1999
Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development
2008
Site-Specific Quantification of Surface N-Glycoproteins in Statin-Treated Liver Cells
2016
CTCF-dependent enhancer-blocking by alternative chromatin loop formation
2008
Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss in Patients With Morbid Obesity
2018 Standout
Hospitalization and Mortality among Black Patients and White Patients with Covid-19
2020 Standout
Loss of Atg12, but not Atg5, in pro-opiomelanocortin neurons exacerbates diet-induced obesity.
2015
Region-Specific Leptin Resistance within the Hypothalamus of Diet-Induced Obese Mice
2004
Protection against diet-induced obesity and obesity- related insulin resistance in Group 1B PLA2-deficient mice
2002
Restoration of leptin responsiveness in diet‐induced obese mice using an optimized leptin analog in combination with exendin‐4 or FGF21
2012
Physiological and Anatomical Circuitry between Agouti-Related Protein and Leptin Signaling*
1999
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
2020 StandoutNobel
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Circumventricular Organs: Gateways to the BrainLeptin Receptors In Hypothalamus And Circumventricular Organs
2001
The Role of Electron Transfer Dissociation in Modern Proteomics
2017
Metabolic reprogramming and cancer progression
2020 StandoutScience
Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview
2019
Molecular signaling involved in regulating feeding and other mitivated behaviors
2007
Obesity is associated with macrophage accumulation in adipose tissue
2003 Standout
CTCF physically links cohesin to chromatin
2008
Rapid Rewiring of Arcuate Nucleus Feeding Circuits by Leptin
2004 Science
Leptin depolarizes rat hypothalamic paraventricular nucleus neurons
1998
Histone Variants and Epigenetics
2015
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
GENETIC MODELS OF OBESITY AND ENERGY BALANCE IN THE MOUSE
2000
Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
2015 Science
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Leptin Receptor Immunoreactivity in Chemically Defined Target Neurons of the Hypothalamus
1998
Gut hormone PYY3-36 physiologically inhibits food intake
2002 StandoutNature
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
2000 StandoutScience
Chemical Glycoproteomics
2016 StandoutNobel
Works of Shu Lin being referenced
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
2013 Science
EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra*
2015
Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH) Analysis for Characterization and Quantification of Histone Post-translational Modifications
2015
Critical Role of Arcuate Y4 Receptors and the Melanocortin System in Pancreatic Polypeptide-Induced Reduction in Food Intake in Mice
2009
Upregulation of leptin receptor mRNA expression in obese mouse brain
1997
Y4 receptors and pancreatic polypeptide regulate food intake via hypothalamic orexin and brain-derived neurotropic factor dependent pathways
2010
Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice
2000
Peripheral neuropeptide Y Y1 receptors regulate lipid oxidation and fat accretion
2009
Pancreatic Polypeptide Controls Energy Homeostasis via Npy6r Signaling in the Suprachiasmatic Nucleus in Mice
2014
NPY and Y receptors: lessons from transgenic and knockout models
2004
Novel Role of Y1 Receptors in the Coordinated Regulation of Bone and Energy Homeostasis
2007
Maintenance of Paternal Methylation and Repression of the Imprinted H19 Gene Requires MBD3
2007
Fasting increases leptin receptor mRNA expression in lean but not obese (ob/ob) mouse brain
1997
Cohesins localize with CTCF at the KSHV latency control region and at cellular c‐myc and H19/Igf2 insulators
2008
NPY Neuron-Specific Y2 Receptors Regulate Adipose Tissue and Trabecular Bone but Not Cortical Bone Homeostasis in Mice
2010
Compensatory changes in [125I]-PYY binding in Y receptor knockout mice suggest the potential existence of further Y receptor(s)
2004
Y1 and Y5 Receptors Are Both Required for the Regulation of Food Intake and Energy Homeostasis in Mice
2012
Intermittent Moderate Energy Restriction Improves Weight Loss Efficiency in Diet-Induced Obese Mice
2016
The role of pancreatic polypeptide in the regulation of energy homeostasis
2015
Peptide YY ablation in mice leads to the development of hyperinsulinaemia and obesity
2006
PYY transgenic mice are protected against diet-induced and genetic obesity
2008
Localization of leptin receptor mRNA expression in mouse brain
1996
Arcuate NPY Controls Sympathetic Output and BAT Function via a Relay of Tyrosine Hydroxylase Neurons in the PVN
2013
Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain
2000
Neuropeptide Y (NPY) Y4Receptor Selective Agonists Based on NPY(32−36): Development of an Anorectic Y4Receptor Selective Agonist with Picomolar Affinity
2006
Bottom-Up and Middle-Down Proteomics Have Comparable Accuracies in Defining Histone Post-Translational Modification Relative Abundance and Stoichiometry
2015
Y1 receptors regulate aggressive behavior by modulating serotonin pathways
2004
Fasting Inhibits the Growth and Reproductive Axes via Distinct Y2 and Y4 Receptor-Mediated Pathways
2007
Y2Y4 Receptor Double Knockout Protects Against Obesity Due to a High-Fat Diet or Y1 Receptor Deficiency in Mice
2006
Nonallelic Transcriptional Roles of CTCF and Cohesins at Imprinted Loci
2011
Quantitative Proteomic Analysis of Histone Modifications
2015