Citation Impact
Citing Papers
Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
2003 Standout
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
Variable phenotype of familial adenomatous polyposis in pedigrees with 3′ mutation in the APC gene
1998
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene.
1996
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
2001 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Three‐dimensional MR mapping of angiogenesis with α 5 β 1 (α v β 3 )‐targeted theranostic nanoparticles in the MDA‐MB‐435 xenograft mouse model
2008
APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis
2000
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms
2001
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Ulcerative Colitis
2011 Standout
A shared and unique peptide in the human colon, eye, and joint detected by a monoclonal antibody
1994
Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism
2002 Standout
Genetics of hereditary colorectal cancer
2005
Tumor Ablation with Radio-frequency Energy
2000
Genetic pathways in colorectal and other cancers
1999
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature
2015
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Vascular Endothelial Growth Factor and Angiogenesis
2004 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
The biology of VEGF and its receptors
2003 Standout
The Epigenomics of Cancer
2007 Standout
APC Genotype, Polyp Number, and Surgical Options in Familial Adenomatous Polyposis
1998
Attenuated familial adenomatous polyposis (AFAP) a phenotypically and genotypically distinctive variant of FAP
1995
Epigenetics in Cancer
2008 Standout
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Targeting Vascular Endothelial Growth Factor (VEGF) for Anti-tumor Therapy, by Anti-VEGF Neutralizing Monoclonal Antibodies or by VEGF Receptor Tyrosine-kinase Inhibitors
1999
A role for MLH3 in hereditary nonpolyposis colorectal cancer
2001
Microdeletions and microinsertions causing human genetic disease: common mechanisms of mutagenesis and the role of local DNA sequence complexity
2005
Oesophageal carcinoma
2013 Standout
The ABC of APC
2001
Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene
1997
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
Novel germline mutations in the APC gene and their phenotypic spectrum in familial adenomatous polyposis kindreds
1997
Mutations of theAPC adenomatous polyposis coli) gene
1993
Hereditary Colorectal Cancer
2003 Standout
EMT: 2016
2016 Standout
The Risk of Cancer Associated with Specific Mutations ofBRCA1andBRCA2among Ashkenazi Jews
1997 Standout
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
1993
Microsatellite Instability in Human Cancer: A Prognostic Marker for Chemotherapy?
1999
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
2002
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
LKB1, a protein kinase regulating cell proliferation and polarity
2003
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
2001
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Mechanism of 5′-Directed Excision in Human Mismatch Repair
2003 StandoutNobel
Behçet's Disease
1999 Standout
Wnt signaling drives WRM-1/β-catenin asymmetries in early C. elegans embryos
2005 StandoutNobel
Attenuated familial adenomatous polyposis due to a mutation in the 3′ part of the APC gene. A clue for understanding the function of the APC protein
1996
Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer
2013
β-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds
2002 Standout
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.
2000
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors).
1997
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer.
2003
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
1999
A systems approach to cancer therapy
1996
Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin
1998 Science
Hepatoblastoma and APC gene mutation in familial adenomatous polyposis.
1996
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
2003 Standout
Surgical treatment of intestinal BehÇet's disease
1997
Tissues of MSH2-deficient mice demonstrate hypermutability on exposure to a DNA methylating agent
1998
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Wnt signaling and cancer
2000 Standout
HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression
2001 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
Chemotherapy of Thyroid Cancer with Adriamycin
1974
Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis.
1999
Multicenter Phase II Study of Irinotecan, Cisplatin, and Bevacizumab in Patients With Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
2006
Brca2 is required for embryonic cellular proliferation in the mouse.
1997 StandoutNobel
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
1997 StandoutScience
Anti-Vascular Endothelial Growth Factor Monoclonals in Non-Small Cell Lung Cancer
2004
ZD4190: an orally active inhibitor of vascular endothelial growth factor signaling with broad-spectrum antitumor efficacy.
2000
Chemotherapy of thyroid cancer. An evaluation of experience with 37 patients
1972
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Overcoming cisplatin resistance in vitro by a free and liposome‐encapsulated bile acid derivative: BAMET‐R2
2000
The Anthracycline Antineoplastic Drugs
1981 Standout
Overcoming cisplatin resistancein vitro by a free and liposome-encapsulated bile acid derivative: BAMET-R2
2000
Human DNA Repair Genes
2001 StandoutScienceNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
2001 Standout
Angiogenesis in Endocrine Tumors
2003
Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review.
2006
Angiogenesis and Tumor Metastasis
1998
Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli
1996
Works of Shozo Baba being referenced
Efficacy of an angiogenesis inhibitor, TNP-470, in xenotransplanted human colorectal cancer with high metastatic potential
1996
Genetic Alterations of Mixed Hyperplastic Adenomatous Polyps in the Colon and Rectum
1998
Antitumor Effect of a Neutralizing Antibody to Vascular Endothelial Growth Factor on Liver Metastasis of Endocrine Neoplasm
1998
Loss or Somatic Mutations of hMSH2 Occur in Hereditary Nonpolyposis Colorectal Cancers with hMSH2 Germline Mutations
1996
Predominant germ-line mutation of thehMSH2 gene in Japanese hereditary non-polyposis colorectal cancer kindreds
1999
Suspected hereditary nonpolyposis colorectal cancer
1999
Nine novel germline mutations of STK11 in ten families with Peutz-Jeghers syndrome
1998
Importance of retinal pigmentation as a subclinical marker in familial adenomatous polyposis
1990
Cytoplasmic Beta-Catenin Accumulation as a Predictor of Hematogenous Metastasis in Human Colorectal Cancer
2000
Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP‐470, and mitomycin c on the growth and liver metastasis of human colon cancer
1995
Anti-tumor and anti-metastatic effects of human-vascular-endothelial-growth-factor-neutralizing antibody on human colon and gastric carcinoma xenotransplanted orthotopically into nude mice
1998
Application of liposomes to the treatment of liver metastasis
1997
Intestinal Behçet's disease
1976
Efficacy of an angiogenesis inhibitor, TNP-470, in xenotransplanted human colorectal cancer with high metastatic potential
1996
Ulcerative colitis complicated by idiopathic central serous chorioretinopathy with bullous retinal detachment
1985
Bleomycin treatment for cancer of the thyroid
1971
Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients.
1992
Resection of Liver Metastases of Colorectal Carcinoma
1997