Citation Impact
Citing Papers
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
2015 StandoutNobel
An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
2010
Origin and Molecular Specification of Striatal Interneurons
2000
Dlx1&2 and Mash1 Transcription Factors Control MGE and CGE Patterning and Differentiation through Parallel and Overlapping Pathways
2009
Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling
2013 StandoutNobel
Molecular evolution of two vertebrate aryl hydrocarbon (dioxin) receptors (AHR1 and AHR2) and the PAS family
1997
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
The aryl hydrocarbon receptor and light
2006
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Evolutionary Genetics of Fish
1991
Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion
2006
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Identification and biochemical analysis of novel olfactory-specific cytochrome P-450IIA and UDP-glucuronosyl transferase
1990
The retention signal for soluble proteins of the endoplasmic reticulum
1990
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Thyroid hormone receptor repression is linked to type I pneumocyte–associated respiratory distress syndrome
2011
DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation
1999
Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus
1998 StandoutNobel
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Bidirectional Transport by Distinct Populations of COPI-Coated Vesicles
1997 StandoutNobel
Generation of Cre-transgenic mice using Dlx1/Dlx2 enhancers and their characterization in GABAergic interneurons
2008
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
The aryl hydrocarbon receptor in immunity
2009
CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells
2009
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
Chapter 3 The Developmental Integration of Cortical Interneurons into a Functional Network
2009
Diagnostic analysis, clinical importance and molecular basis of dihydropyrimidine dehydrogenase deficiency
1995
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
1990 StandoutNature
TH2 Cytokines and Allergic Challenge Induce Ym1 Expression in Macrophages by a STAT6-dependent Mechanism
2002
A long, remarkable journey: Tangential migration in the telencephalon
2001
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Isolation and Expression of cDNAs from Rainbow Trout (Oncorhynchus mykiss) That Encode Two Novel Basic Helix-Loop-Helix/PER-ARNT-SIM (bHLH/PAS) Proteins with Distinct Functions in the Presence of the Aryl Hydrocarbon Receptor
1996
Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq
2014 Nature
Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy
2005
Fate mapping Nkx2.1‐lineage cells in the mouse telencephalon
2007
Multipotent embryonic spinal cord stem cells expanded by endothelial factors and Shh/RA promote functional recovery after spinal cord injury
2007
HIF-1alpha is required for solid tumor formation and embryonic vascularization
1998
Sonic Hedgehog Signaling Confers Ventral Telencephalic Progenitors with Distinct Cortical Interneuron Fates
2010
Human UDP‐glucuronosyl transferases: Chemical defence, jaundice and gene therapy
1993
Neuroligin 1: A splice site-specific ligand for β-neurexins
1995 StandoutNobel
PDGF‐a/PDGF alpha‐receptor signaling is required for lung growth and the formation of alveoli but not for early lung branching morphogenesis
2001
Loss of teratogenic response to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) in mice lacking the Ah (dioxin) receptor
1997
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
2008 StandoutNobel
Portrait of PTEN: Messages from mutant mice
2008 StandoutNobel
Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: Potential for understanding NKX2.1 haploinsufficiency in humans?
2009
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Spatial Genetic Patterning of the Embryonic Neuroepithelium Generates GABAergic Interneuron Diversity in the Adult Cortex
2007
Telomeric repeat from T. thermophila cross hybridizes with human telomeres
1988 StandoutNatureNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Gene Expression in Cortical Interneuron Precursors is Prescient of their Mature Function
2008
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
Evolution of the P450 gene superfamily:
1990
Generation of interneuron diversity in the mouse cerebral cortex
2010
Ah receptor and NF-κB interactions: mechanisms and physiological implications
2002
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Delineation of Multiple Subpallial Progenitor Domains by the Combinatorial Expression of Transcriptional Codes
2007
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling
1997
A Role for Intermediate Radial Glia in the Tangential Expansion of the Mammalian Cerebral Cortex
2010
Constitutive and Inducible Cytochromes P450 in Rat Lung Mitochondria: Xenobiotic Induction, Relative Abundance, and Catalytic Properties
1999
Genetic Fate Mapping Reveals That the Caudal Ganglionic Eminence Produces a Large and Diverse Population of Superficial Cortical Interneurons
2010
Physiologically Distinct Temporal Cohorts of Cortical Interneurons Arise from Telencephalic Olig2 -Expressing Precursors
2007
A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex
2011 Standout
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
1993 StandoutNobel
Type 2 alveolar cells are stem cells in adult lung
2013 Standout
Bronchopulmonary Dysplasia
2001 Standout
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family.
1987
Geometric and Electronic Structure/Function Correlations in Non-Heme Iron Enzymes
1999 Standout
Splicing in Caenorhabditis elegans does not require an AG at the 3' splice acceptor site.
1993
Nucleotide sequence of cDNA coding for rat liver pI 6.1 esterase (ES-10), a carboxylesterase located in the lumen of the endoplasmic reticulum
1990
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.
1995 StandoutNobel
Human cytochrome P-450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10.
1988
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
Oligodendrocyte development in the spinal cord and telencephalon: common themes and new perspectives
2001
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.
1995 StandoutNobel
Clinical significance of the sparteine/debrisoquine oxidation polymorphism
1989
CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT
2005
MOLECULAR MECHANISMS OF GENETIC POLYMORPHISMS OF DRUG METABOLISM
1997
Relationship between sequence conservation and three‐dimensional structure in a large family of esterases, lipases, and related proteins
1993
Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension
1996 StandoutNobel
PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR –ACTIVATED RECEPTOR α: An Adaptive Metabolic System
2001
Functional Interference between Hypoxia and Dioxin Signal Transduction Pathways: Competition for Recruitment of the Arnt Transcription Factor
1996
AH RECEPTOR SIGNALING PATHWAYS
1996
A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors
2002
The Glial Nature of Embryonic and Adult Neural Stem Cells
2009 Standout
The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases.
1990
Odorant-selective genes and neurons mediate olfaction in C. elegans
1993 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
[51] Cloning of sheep and mouse prostaglandin endoperoxide synthases
1990
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
2002 StandoutNobel
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
2004
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
2010 StandoutNobel
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.
1996
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
1991 Standout
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor
2007
Works of Shioko Kimura being referenced
Pten Loss in the Mouse Thyroid Causes Goiter and Follicular Adenomas: Insights into Thyroid Function and Cowden Disease Pathogenesis
2007
The Rat Clofibrate-Inducible CYP4A Subfamily II. cDNA Sequence of IVA3, Mapping of the Cyp4a Locus to Mouse Chromosome 4, and Coordinate and Tissue-Specific Regulation of the CYP4A Genes
1989
The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping
1990
Postmitotic Nkx2-1 Controls the Migration of Telencephalic Interneurons by Direct Repression of Guidance Receptors
2008
The Requirement of Nkx2-1 in the Temporal Specification of Cortical Interneuron Subtypes
2008
Deletion of theTtf1Gene in Differentiated Neurons Disrupts Female Reproduction without Impairing Basal Ganglia Function
2006
Assignment of the Human Dihydropyrimidine Dehydrogenase Gene (DPYD) to Chromosome Region 1p22 by Fluorescence in Situ Hybridization
1994
Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression
2006
Immunohistochemical analyses of thyroid-specific enhancer-binding protein in the fetal and adult rat hypothalami and pituitary glands
2001
In vivo characterization of the Nkx2.1 promoter/enhancer elements in transgenic mice
2004
Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism
1993
Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene
1989
Correlation between catalytic activity and protein content for the polymorphically expressed dihydropyrimidine dehydrogenase in human lymphocytes
1995
Hyalinosis and Ym1/Ym2 Gene Expression in the Stomach and Respiratory Tract of 129S4/SvJae and Wild-Type and CYP1A2-Null B6,129 Mice
2001
The Progenitor Zone of the Ventral Medial Ganglionic Eminence Requires Nkx2-1 to Generate Most of the Globus Pallidus But Few Neocortical Interneurons
2010
Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin-Binding Ah Receptor
1995 Science
Rat liver carboxylesterase: cDNA cloning, sequencing, and evidence for a multigene family
1988
Defects in Tracheoesophageal and Lung Morphogenesis inNkx2.1(−/−) Mouse Embryos
1999
Human myeloperoxidase and thyroid peroxidase, two enzymes with separate and distinct physiological functions, are evolutionarily related members of the same gene family
1988
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.
1996
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
1988 Nature
Thyroid-Specific Enhancer-Binding Protein/NKX2.1 Is Required for the Maintenance of Ordered Architecture and Function of the Differentiated Thyroid
2006
Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.
1991
GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo
2006
Structure and regulation of rat long-chain acyl-CoA synthetase.
1990
The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.
1989
Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs.
1987
Formation of Rathke’s pouch requires dual induction from the diencephalon
1998
Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.
1986
A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.
1992
Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum
1999
Unusual low-frequency resonance Raman spectra of heme observed for hog intestinal peroxidase and its derivatives
1981
Disruption of Lymphocyte Function and Signaling in CD45–associated Protein–null Mice
1998
Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon
2001
Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways
2012
Sequence of two related P-450 mRNAs transcriptionally increased during rat development. An R.dre.1 sequence occupies the complete 3' untranslated region of a liver mRNA.
1986
Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.
1985
claudin-18, a Novel Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor, Encodes Lung- and Stomach-Specific Isoforms through Alternative Splicing
2001
The human CYP2D locus associated with a common genetic defect in drug oxidation: a G1934----A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site.
1990
Targeted Disruption of the Microsomal Epoxide Hydrolase Gene
1999