Citation Impact
Citing Papers
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
2009 StandoutScience
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Regulation of B Versus T Lymphoid Lineage Fate Decision by the Proto-Oncogene LRF
2007 Science
Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism
2012 Science
ZBTB1 is a determinant of lymphoid development
2011 StandoutNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells
2011
Emerging roles of PKM2 in cell metabolism and cancer progression
2012 StandoutNobel
G9a inhibition induced PKM2 regulates autophagic responses
2016
C/EBPα and C/EBPβ Are Required for Sebocyte Differentiation and Stratified Squamous Differentiation in Adult Mouse Skin
2010
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Prolactin Inhibits Activity of Pyruvate Kinase M2 to Stimulate Cell Proliferation
2010
Transcription factors in myeloid development: balancing differentiation with transformation
2007
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
2016
Protein lipoylation: an evolutionarily conserved metabolic regulator of health and disease
2017
Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions
2012
Transcriptional regulation by hypoxia inducible factors
2013
New plays in the p53 theater
2010
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
2012 Nature
Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase
2011
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
2010
Anti‐aging activity of the Ink4/Arf locus
2009
MUC1-C Oncoprotein Regulates Glycolysis and Pyruvate Kinase m2 Activity in Cancer Cells
2011
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells
2010
Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons
2011
PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors
2018
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
2011
Neutrophils, from Marrow to Microbes
2010 Standout
Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
2010
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Pyruvate kinase: Function, regulation and role in cancer
2015
Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice
2010
Dysregulated pH: a perfect storm for cancer progression
2011 Standout
The Transcriptional Regulation of B Cell Lineage Commitment
2007
Myeloid Lineage Commitment from the Hematopoietic Stem Cell
2007
Clonal evolution in cancer
2012 StandoutNature
The Hallmarks of Aging
2013 Standout
Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes
2012
Regulation of Metabolism by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Reprogramming of Committed T Cell Progenitors to Macrophages and Dendritic Cells by C/EBPα and PU.1 Transcription Factors
2006
The Kruppel‐like factor KLF4 is a critical regulator of monocyte differentiation
2007
Mitochondria and cancer
2012 Standout
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Autophagy in immunity and inflammation
2011 StandoutNature
Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myeloerythroid and Myelolymphoid Lineages
2007
Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
2012
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells
2010
Clues from cell metabolism
2010 StandoutNatureNobel
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells
2009
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
2011 Standout
PU.1 and C/EBPα/β convert fibroblasts into macrophage-like cells
2008
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells
2011 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
PKM2 Tyrosine Phosphorylation and Glutamine Metabolism Signal a Different View of the Warburg Effect
2009
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation
2012
Metabolic reprogramming and cancer progression
2020 StandoutScience
No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis
2011
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
2010
Cancer Genome Landscapes
2013 StandoutScience
Fueling Immunity: Insights into Metabolism and Lymphocyte Function
2013 Science
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Shannon Elf being referenced
p53 Regulates Hematopoietic Stem Cell Quiescence
2009
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis
2007
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin
2016
Tyr-301 Phosphorylation Inhibits Pyruvate Dehydrogenase by Blocking Substrate Binding and Promotes the Warburg Effect
2014
Respiratory Failure Due to Differentiation Arrest and Expansion of Alveolar Cells following Lung-Specific Loss of the Transcription Factor C/EBPα in Mice
2006
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
2009
Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation
2005
Fibroblast Growth Factor Receptor 3 Associates with and Tyrosine Phosphorylates p90 RSK2, Leading to RSK2 Activation That Mediates Hematopoietic Transformation
2009