Citation Impact
Citing Papers
Infection, inflammation, height, and longevity
2005 Standout
Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)
1999 Standout
Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host
2004
The MyD88-Dependent, but Not the MyD88-Independent, Pathway of TLR4 Signaling Is Important in Clearing Nontypeable Haemophilus influenzae from the Mouse Lung
2005 StandoutNobel
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
1998 StandoutNature
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Recognition of Gram-negative bacteria and endotoxin by the innate immune system
1999
CONCENTRATIONS OF LIPOPOLYSACCHARIDE-BINDING PROTEIN, BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN, SOLUBLE CD14 AND PLASMA LIPIDS IN RELATION TO ENDOTOXAEMIA IN PATIENTS WITH ALCOHOLIC LIVER DISEASE
2002
Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2
1999 Standout
Molecular mechanisms of endotoxin activity
1995
Toll-like Receptors and Innate Immunity
2001
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
2004 Standout
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
2001 StandoutNature
Early Immunologic Failure is Associated With Early Mortality Among Advanced HIV–Infected Adults Initiating Antiretroviral Therapy With Active Tuberculosis
2013 StandoutNobel
Interaction between high-density lipoproteins and inflammation: Function matters more than concentration!
2020
Saturated Fatty Acid Activates but Polyunsaturated Fatty Acid Inhibits Toll-like Receptor 2 Dimerized with Toll-like Receptor 6 or 1
2004 Standout
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2012 StandoutNobel
Binding of Bacterial Peptidoglycan to CD14
1998
The changing landscape of atherosclerosis
2021 StandoutNature
Catalytic Properties of Lipopolysaccharide (LPS) Binding Protein
1996
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
2006 Standout
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
2013 Standout
Inflammation, stress, and diabetes
2005 Standout
Genetic-dietary regulation of serum paraoxonase expression and its role in atherogenesis in a mouse model.
1996
Complement: a key system for immune surveillance and homeostasis
2010 Standout
Intracellular Toll-like Receptors
2010 StandoutNobel
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction
1999 Standout
Recognition of Pneumococcal Peptidoglycan
2003
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection
1997 Nature
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
2000 Standout
A comparative analysis of cytokine production and tolerance induction by bacterial lipopeptides, lipopolysaccharides and Staphyloccocus aureus in human monocytes
1997
PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene
2000 StandoutNobel
Combinations of ERK and p38 MAPK Inhibitors Ablate Tumor Necrosis Factor-α (TNF-α) mRNA Induction
2001
HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
2000 Standout
Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation
2010 Standout
Toll receptors in innate immunity
2001 StandoutNobel
Sickle-cell disease
2010 Standout
The endotoxin-lipoprotein hypothesis
2000
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Myocarditis
2000 Standout
Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction
2003
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins
2000
Toll-like receptors and innate immunity
2009
Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.
1997
Endotoxin and immune activation in chronic heart failure: a prospective cohort study
1999
Treponemal Phospholipids Inhibit Innate Immune Responses Induced by Pathogen-associated Molecular Patterns
2003
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
Combined Serum Paraoxonase Knockout/Apolipoprotein E Knockout Mice Exhibit Increased Lipoprotein Oxidation and Atherosclerosis
2000 Standout
Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections.
1996
Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.
1998 Standout
Modulatory effects of sCD14 and LBP on LPS-host cell interactions
2005
Lipopolysaccharide‐induced production of tumour necrosis factor and interleukin‐1 is differentially regulated at the receptor level: the role of CD14‐dependent and CD14‐independent pathways
1998
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
Regulation of interactions of endotoxin with host cells
2003
Interactions between Lipid A and Serum Proteins
2009
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
The immunopathogenesis of sepsis
2002 StandoutNature
Involvement of CD14 and Complement Receptors CR3 and CR4 in Nuclear Factor-κB Activation and TNF Production Induced by Lipopolysaccharide and Group B Streptococcal Cell Walls
1998
Recognition of Bacterial Endotoxin in the Lungs
2000
New Approaches to Sepsis: Molecular Diagnostics and Biomarkers
2012
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Toll-Like Receptors
2003 Standout
Receptors, Mediators, and Mechanisms Involved in Bacterial Sepsis and Septic Shock
2003
Soluble CD141–152 Confers Responsiveness to Both Lipoarabinomannan and Lipopolysaccharide in a Novel HL-60 Cell Bioassay
1998
Inducible Expression of Human β-Defensin 2 byFusobacterium nucleatumin Oral Epithelial Cells: Multiple Signaling Pathways and Role of Commensal Bacteria in Innate Immunity and the Epithelial Barrier
2000
Elevated Levels of Serum-Soluble CD14 in Human Immunodeficiency Virus Type 1 (HIV-1) Infection: Correlation to Disease Progression and Clinical Events
1998
Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis
1996
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2
1999 StandoutScience
Molecular Physiology of P2X Receptors
2002 Standout
Genetics of O-Antigen Biosynthesis inPseudomonas aeruginosa
1999
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
2001 Standout
Cutting Edge: The Nucleotide Receptor P2X7 Contains Multiple Protein- and Lipid-Interaction Motifs Including a Potential Binding Site for Bacterial Lipopolysaccharide
2001
Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein.
1995
Low Endotoxic Potential ofLegionella pneumophilaLipopolysaccharide due to Failure of Interaction with the Monocyte Lipopolysaccharide Receptor CD14
1998
CD14-Mac-1 interactions inBacillus anthracisspore internalization by macrophages
2009
Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact
1997
Renal Function as a Predictor of Outcome in a Broad Spectrum of Patients With Heart Failure
2006 Standout
Effect of Spaceflight on Ability of Monocytes To Respond to Endotoxins of Gram-Negative Bacteria
2008
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
2004 Standout
The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
2009 StandoutNature
Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages
2000
Customizing the genome as therapy for the β-hemoglobinopathies
2016
Modulatory effects of sCD14 and LBP on LPS-host cell interactions
2005
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
Lipopolysaccharide Endotoxins
2002 Standout
Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls.
1998
Toll‐like receptors: molecular mechanisms of the mammalian immune response
2000
Innate Immune Recognition
2002 Standout
Lipopolysaccharide binding protein promoter variants influence the risk for Gram-negative bacteremia and mortality after allogeneic hematopoietic cell transplantation
2007
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Membrane-Anchored Forms of Lipopolysaccharide (LPS)-Binding Protein Do Not Mediate Cellular Responses to LPS Independently of CD14
1999
Bacille Calmette-Guérin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes
2012 Standout
LPS-binding proteins and receptors
1998
A Point Mutation in the Amino Terminus of TLR7 Abolishes Signaling without Affecting Ligand Binding
2011 StandoutNobel
Works of Shaela Wright being referenced
Chemical characteristics of Staphylococcus aureus molecules that have CD14-dependent cell-stimulating activity.
1996
Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS.
1994
Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and subsequent immune cell activation.
1996
Genome Editing Recreates Hereditary Persistence of Fetal Hemoglobin in Primary Human Erythroblasts
2015