Standout Papers
- Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds (2011)
- A Nontranscriptional Role for HIF-1α as a Direct Inhibitor of DNA Replication (2013)
- Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia (2007)
- Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells (2012)
- Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells (2011)
- Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling (2010)
- Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth (2008)
- Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue (2011)
- Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors (2012)
- Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia (2009)
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
A Novel Two-Stage, Transdisciplinary Study Identifies Digoxin as a Possible Drug for Prostate Cancer Treatment
2011
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition
2012
Differential expressions and roles of hypoxia-inducible factor-1alpha, -2alpha and -3alpha in the rat carotid body during chronic and intermittent hypoxia.
2008
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Hypoxia-inducible factors regulate human and rat cystathionine β-synthase gene expression
2013 StandoutNobel
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1α Expression in an AhR-Independent Fashion
2010
Hallmarks of Cancer: The Next Generation
2011 Standout
Regulation of hypoxia‐inducible factor‐α isoforms and redox state by carotid body neural activity in rats
2014 StandoutNobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Breast Tumor Kinase (Brk/PTK6) Is a Mediator of Hypoxia-Associated Breast Cancer Progression
2013
Central and peripheral factors contributing to obstructive sleep apneas
2013
Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1α
2010
Impaired angiogenesis and mobilization of circulating angiogenic cells in HIF-1α heterozygous-null mice after burn wounding
2010 StandoutNobel
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Time-dependent adaptation in the hemodynamic response to hypoxia
2008
Heterozygous HIF‐1α deficiency impairs carotid body‐mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
2006 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
2012 StandoutNobel
HIF-1α in Epidermis: Oxygen Sensing, Cutaneous Angiogenesis, Cancer, and Non-Cancer Disorders
2011
Neonatal Intermittent Hypoxia Leads to Long-Lasting Facilitation of Acute Hypoxia-Evoked Catecholamine Secretion From Rat Chromaffin Cells
2009
Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
2010 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Carotid body function in heart failure
2007
The hypoxic tumor microenvironment: A driving force for breast cancer progression
2015 StandoutNobel
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Age‐dependent impairment of HIF‐1α expression in diabetic mice: Correction with electroporation‐facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells
2008 StandoutNobel
Systemic, cellular and molecular analysis of chemoreflex‐mediated sympathoexcitation by chronic intermittent hypoxia
2006
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Hypoxia‐inducible factor 1 mediates increased expression of NADPH oxidase‐2 in response to intermittent hypoxia
2011 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer
2013 StandoutNobel
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats
2006
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Peripheral Chemoreceptors: Function and Plasticity of the Carotid Body
2012
Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment
2013
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
2011
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Cardiovascular disease in obstructive sleep apnoea syndrome: the role of intermittent hypoxia and inflammation
2009
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Peripheral Chemoreception and Arterial Pressure Responses to Intermittent Hypoxia
2015
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Oxygen homeostasis
2009 StandoutNobel
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
HIF and the Lung
2011 StandoutNobel
ROS Signaling in Systemic and Cellular Responses to Chronic Intermittent Hypoxia
2007 StandoutNobel
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
2014 StandoutNobel
Effect of Hypoxia-Inducible Factor-1α Gene Therapy on Walking Performance in Patients With Intermittent Claudication
2011
Digoxin inhibits retinal ischemia‐induced HIF‐1α expression and ocular neovascularization
2010 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy
2013 StandoutNobel
Stabilization of HIF-1α is critical to improve wound healing in diabetic mice
2008
Therapeutic Targeting of the Tumor Microenvironment
2021
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
Role of Hypoxia-Inducible Factors in Breast Cancer Metastasis
2013 StandoutNobel
Sympatho-adrenal activation by chronic intermittent hypoxia
2012
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Inhibition of Prolyl Hydroxylase Domain Proteins Promotes Therapeutic Revascularization
2009
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
2013 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Pathophysiology of Sleep Apnea
2010 Standout
HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells
2015 StandoutNobel
HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury
2010 StandoutNobel
O2 Regulates Skeletal Muscle Progenitor Differentiation through Phosphatidylinositol 3-Kinase/AKT Signaling
2011
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1
2009 StandoutNobel
Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long‐term intermittent hypoxia
2016 StandoutNobel
Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia
2011
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
CaV3.2 T-type Ca2+channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia
2015
Works of Sergio Rey being referenced
Chronic intermittent hypoxia enhances cat chemosensory and ventilatory responses to hypoxia
2004
Hypoxia: Turning vessels into vassals of cancer immunotolerance
2020
Contribution of Endothelin-1 and Endothelin A and B Receptors to the Enhanced Carotid Body Chemosensory Responses Induced by Chronic Intermittent Hypoxia
2007
Aging impairs the mobilization and homing of bone marrow-derived angiogenic cells to burn wounds
2011 StandoutNobel
Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells
2011 StandoutNobel
Contribution of endothelin-1 to the enhanced carotid body chemosensory responses induced by chronic intermittent hypoxia
2006
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling
2010 StandoutNobel
Lipopolysaccharide‐induced carotid body inflammation in cats: functional manifestations, histopathology and involvement of tumour necrosis factor‐α
2008
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Matrix Rigidity Controls Endothelial Differentiation and Morphogenesis of Cardiac Precursors
2012 StandoutNobel
A Nontranscriptional Role for HIF-1α as a Direct Inhibitor of DNA Replication
2013 StandoutNobel
Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia
2007 StandoutNobel
Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue
2011 StandoutNobel
Inhibitory effects of NO on carotid body: contribution of neural and endothelial nitric oxide synthase isoforms
2003
Expression and Immunolocalization of Endothelin Peptides and Its Receptors, ETA and ETB, in the Carotid Body Exposed to Chronic Intermittent Hypoxia
2006
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel