Citation Impact
Citing Papers
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
2002
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
2009 StandoutScience
Coordinated plant defense responses in Arabidopsis revealed by microarray analysis
2000 Standout
Separate jasmonate-dependent and salicylate-dependent defense-response pathways in Arabidopsis are essential for resistance to distinct microbial pathogens
1998
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 Standout
Arabidopsis gp91 phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response
2001
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice
2010
Effect of Mutant α-Synuclein on Dopamine Homeostasis in a New Human Mesencephalic Cell Line
2002
Pathological Changes in Dopaminergic Nerve Cells of the Substantia Nigra and Olfactory Bulb in Mice Transgenic for Truncated Human α-Synuclein(1–120): Implications for Lewy Body Disorders
2006
Reactive oxygen species produced by NADPH oxidase regulate plant cell growth
2003 StandoutNature
Effect of the overexpression of wild‐type or mutant α‐synuclein on cell susceptibility to insult
2001
H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response
1994 Standout
The role and regulation of programmed cell death in plant-pathogen interactions
2004
Elicitor- and wound-induced oxidative cross-linking of a proline-rich plant cell wall protein: A novel, rapid defense response
1992 Standout
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Systemic Acquired Resistance
1994
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Oxidative stress, antioxidants and stress tolerance
2002 Standout
Pathogen-induced, NADPH oxidase–derived reactive oxygen intermediates suppress spread of cell death in Arabidopsis thaliana
2005
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein
2004
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Alpha-synuclein and transgenic mouse models
2004
The Co-chaperone Carboxyl Terminus of Hsp70-interacting Protein (CHIP) Mediates α-Synuclein Degradation Decisions between Proteasomal and Lysosomal Pathways
2005
Selective loss of nigral dopamine neurons induced by overexpression of truncated human α-synuclein in mice
2006
Genetic Animal Models of Parkinson's Disease
2010
A Broken α-Helix in Folded α-Synuclein
2003 StandoutNobel
Part II: α-synuclein and its molecular pathophysiological role in neurodegenerative disease
2003
Differential neuropathological alterations in transgenic mice expressing α‐synuclein from the platelet‐derived growth factor and Thy‐1 promoters
2002
Plants have a sensitive perception system for the most conserved domain of bacterial flagellin
1999
Rare genetic mutations shed light on the pathogenesis of Parkinson disease
2003
α‐Synuclein metabolism and aggregation is linked to ubiquitin‐independent degradation by the proteasome
2001
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
The 1.8 Å Resolution Structure of Hevamine, a Plant Chitinase/Lysozyme, and Analysis of the Conserved Sequence and Structure Motifs of Glycosyl Hydrolase Family 18
1996
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Isolation and Characterization of the Genes Encoding Basic and Acidic Chitinase in Arabidopsis thaliana
1990
Membrane-bound α-Synuclein Has a High Aggregation Propensity and the Ability to Seed the Aggregation of the Cytosolic Form
2002
Defining the core Arabidopsis thaliana root microbiome
2012 StandoutNature
Revealing structure and assembly cues for Arabidopsis root-inhabiting bacterial microbiota
2012 StandoutNature
Structural Organization of α-Synuclein Fibrils Studied by Site-directed Spin Labeling
2003
Early Responses of Tobacco Suspension Cells to Rhizobacterial Elicitors of Induced Systemic Resistance
2008
Leaf-specific thionins of barley-a novel class of cell wall proteins toxic to plant-pathogenic fungi and possibly involved in the defence mechanism of plants
1988
Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP111-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
2003
Cloning and expression of a PR5-like protein from Arabidopsis: inhibition of fungal growth by bacterially expressed protein
1997
Plant pathogens and integrated defence responses to infection
2001 StandoutNature
Pathogenesis of parkinson's disease: dopamine, vesicles and α-synuclein
2002
A Progressive Mouse Model of Parkinson's Disease: The Thy1-aSyn (“Line 61”) Mice
2012
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
2013
Parkin Protects against the Toxicity Associated with Mutant α-Synuclein
2002
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
2001
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
2006 Standout
Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease
2008
Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death
2006
Structure/function of α‐synuclein in health and disease: rational development of animal models for Parkinson's and related diseases
2002
MAP kinase signalling cascade in Arabidopsis innate immunity
2002 StandoutNature
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons
2003
Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
2001
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Alpha-synuclein and neurodegenerative diseases
2001
The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
2007 StandoutNobel
Selective Insolubility of α-Synuclein in Human Lewy Body Diseases Is Recapitulated in a Transgenic Mouse Model
2001
Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
2002
Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits α-Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions
2010
Isochorismate synthase is required to synthesize salicylic acid for plant defence
2001 StandoutNature
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
The genomes of closely related Pantoea ananatis maize seed endophytes having different effects on the host plant differ in secretion system genes and mobile genetic elements
2015
Targeting programmed cell death in neurodegenerative diseases
2003
Non-invasive imaging of neuropathology in a rat model of α-synuclein overexpression
2006
Inhibition of NF-κB by Sodium Salicylate and Aspirin
1994 StandoutScience
Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter
2001
Signals and transduction mechanisms for activation of plant defenses against microbial attack
1989
The role of the C-terminus of human α-synuclein: Intra-disulfide bonds between the C-terminus and other regions stabilize non-fibrillar monomeric isomers
2011
Innate immunity in plants and animals: striking similarities and obvious differences
2004
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein
2002
The plant immune system
2006 StandoutNature
Parkinson's Disease
2003 Standout
Living inside plants: bacterial endophytes
2011
Cell death pathways in Parkinson’s disease: proximal triggers, distal effectors, and final steps
2009
CTR1, a negative regulator of the ethylene response pathway in arabidopsis, encodes a member of the Raf family of protein kinases
1993 Standout
Pivoting the Plant Immune System from Dissection to Deployment
2013 StandoutScience
Activation, Structure, and Organization of Genes Involved in Microbial Defense in Plants
1990
Uncoupling PR Gene Expression from NPR1 and Bacterial Resistance: Characterization of the Dominant Arabidopsis cpr6-1 Mutant
1998
Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene
2003
The Hidden World within Plants: Ecological and Evolutionary Considerations for Defining Functioning of Microbial Endophytes
2015 Standout
A Harpin Binding Site in Tobacco Plasma Membranes Mediates Activation of the Pathogenesis-Related Gene HIN1 Independent of Extracellular Calcium but Dependent on Mitogen-Activated Protein Kinase Activity
2001
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
A Role for α-Synuclein in the Regulation of Dopamine Biosynthesis
2002
Differential expression of five Arabidopsis genes encoding glycine-rich proteins.
1990
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Granules of the Human Neutrophilic Polymorphonuclear Leukocyte
1997 Standout
Active Oxygen Species in the Induction of Plant Systemic Acquired Resistance by Salicylic Acid
1993 StandoutScience
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.
2002
Coordinate Gene Activity in Response to Agents That Induce Systemic Acquired Resistance.
1991
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Pathogen-induced proteins with inhibitory activity toward Phytophthora infestans.
1991
Neutrophil Extracellular Traps Kill Bacteria
2004 StandoutScience
Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult
2001
Increased tolerance to two oomycete pathogens in transgenic tobacco expressing pathogenesis-related protein 1a.
1993
Zeroing in on the Pathogenic Form of α-Synuclein and Its Mechanism of Neurotoxicity in Parkinson's Disease
2003
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Ethylene Signal Is Transduced via Protein Phosphorylation Events in Plants.
1993
A role for alpha-synuclein in the regulation of dopamine biosynthesis.
2002
α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
2002
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
2002
A Central Role of Salicylic Acid in Plant Disease Resistance
1994 StandoutScience
Salicylic Acid: A Likely Endogenous Signal in the Resistance Response of Tobacco to Viral Infection
1990 Science
Transgenic tobacco plants with reduced capability to detoxify reactive oxygen intermediates are hyperresponsive to pathogen infection
1999
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system
1998 StandoutNobel
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Map-Based Cloning of a Protein Kinase Gene Conferring Disease Resistance in Tomato
1993 StandoutScience
Drosophila parkinmutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
2004
Works of Serge Kauffmann being referenced
Plant ‘pathogenesis-related’ proteins and their role in defense against pathogens
1993
Defense and Resistance-inducing Activities in Tobacco of the Sulfated β-1,3 glucan PS3 and its Synergistic Activities with the Unsulfated Molecule
2005
Biological function of ‘pathogenesis-related’ proteins: four PR proteins of tobacco have 1,3-β-glucanase activity
1987
A new elicitor of the hypersensitive response in tobacco: a fungal glycoprotein elicits cell death, expression of defence genes, production of salicylic acid, and induction of systemic acquired resistance
1995
Molecular characterization of a novel tobacco pathogenesis-related (PR) protein: a new plant chitinase/lysozyme
1994
Mouse models of α-synucleinopathy and Lewy pathology
2000
Comparative analysis of defence responses induced by the endophytic plant growth-promoting rhizobacterium Burkholderia phytofirmans strain PsJN and the non-host bacterium Pseudomonas syringae pv. pisi in grapevine cell suspensions
2010
Homology between chitinases that are induced by TMV infection of tobacco
1987
Isolation and characterization of six pathogenesis-related (PR) proteins of Samsun NN tobacco
1990
Identification and characterization of maize pathogenesis-related proteins. Four maize PR proteins are chitinases
1988
Tobacco Class I and II Catalases Are Differentially Expressed During Elicitor-Induced Hypersensitive Cell Death and Localized Acquired Resistance
1998
Biological function of pathogenesis-related proteins: Four tobacco pathogenesis-related proteins are chitinases
1987
β-1,3 Glucan Sulfate, but Not β-1,3 Glucan, Induces the Salicylic Acid Signaling Pathway in Tobacco and Arabidopsis
2004
Constitutive expression of pathogenesis-related proteins PR-1, GRP, and PR-S in tobacco has no effect on virus infection.
1989
Hydrogen Peroxide from the Oxidative Burst Is Neither Necessary Nor Sufficient for Hypersensitive Cell Death Induction, Phenylalanine Ammonia Lyase Stimulation, Salicylic Acid Accumulation, or Scopoletin Consumption in Cultured Tobacco Cells Treated with Elicitin
1999
Tobacco Mesophyll Protoplasts Synthesize 1,3-β-Glucanase, Chitinases, and “Osmotins” during in Vitro Culture
1990
Spatial and Temporal Induction of Cell Death, Defense Genes, and Accumulation of Salicylic Acid in Tobacco Leaves Reacting Hypersensitively to a Fungal Glycoprotein Elicitor
1997
Neuropathology in mice expressing human alpha-synuclein
2000
Relationship Between Localized Acquired Resistance (LAR) and the Hypersensitive Response (HR): HR Is Necessary for LAR to Occur and Salicylic Acid Is Not Sufficient to Trigger LAR
1999