Citation Impact
Citing Papers
Synthesis of carbocyclic nucleosides
1994
Covalent inhibitors of glycosidases and their applications in biochemistry and biology
2008
A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase
2001
Serotonin 5‐HT1B and 5‐HT1D receptors form homodimers when expressed alone and heterodimers when co‐expressed
1999
Purine nucleoside phosphorylases: properties, functions, and clinical aspects
2000
Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT1B receptor
1999
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Novel 3-phenylprop-2-ynylamines as inhibitors of mammalian squalene epoxidaseElectronic supplementary information (ESI) available: Proton NMR spectra for the intermediate piperidines 56–60 and acetylenes 63-81 and 85,86. See http://www.rsc.org/suppdata/ob/b2/b209165h/
2003
Crystal Structure of Calf Spleen Purine Nucleoside Phosphorylase with Two Full Trimers in the Asymmetric Unit: Important Implications for the Mechanism of Catalysis
2004 StandoutNobel
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
Purine nucleoside phosphorylase: A target for drug design
1993
Carbon–heteroatom bond formation catalysed by organometallic complexes
2008 StandoutNature
Computational Enzyme Design
2013 StandoutNobel
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates
2004 StandoutNobel
Mitogen activated protein kinase inhibitors: where are we now and where are we going?
2006
Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor
2004
The 7 TM G‐Protein‐Coupled Receptor Target Family
2006
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Catalytic antibodies: hapten design strategies and screening methods
2004
Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs
1999
Migraine — Current Understanding and Treatment
2002 Standout
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
2009
Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3
2008 StandoutNobel
Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 Å resolution
1997
Binding of phosphate and sulfate anions by purine nucleoside phosphorylase from E. coli: ligand-dependent quenching of enzyme intrinsic fluorescence
1997
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Copper(I)‐Catalyzed Cycloaddition of Organic Azides and 1‐Iodoalkynes
2009 StandoutNobel
Homo- and Hetero-oligomerization of Thyrotropin-releasing Hormone (TRH) Receptor Subtypes
2002 StandoutNobel
N-Bromoacetyl-glycopyranosylamines as affinity labels for a β-glucosidase and a cellulase
1993
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Der Zugang zum Antitumor‐Antibiotikum CC‐1065 mittels Hetero‐Cope‐Umlagerung von Vinyl‐N‐phenylhydroxamaten
1989
3,4-Bis(trimethylsilyl)-1H-pyrrole: a versatile building block for unsymmetrically 3,4-disubstituted pyrroles
1997
Rhodium-Catalyzed Hydroformylation of Cyclopropenes
2008
Fluorine in medicinal chemistry
2007 Standout
Donitriptan, a Unique High‐Efficacy 5‐HT1B/1DAgonist: Key Features and Acute Antimigraine Potential
2000
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Synthesis of (-)-periplanone-B a sex pheromone component of the American cockroach (periplaneta americana)
1990
Acetylenkupplungen: eine leistungsfähige Methode für den Aufbau von Molekülen
2000
Preparation of 3-hydroxyl-vinyl selenides and 1,3-bis(seleeno)-propenes
1985
Drug Efficacy at G Protein–Coupled Receptors
2002
Design, Synthesis, and Biological Evaluation of 3-(1-Aryl-1H-indol-5-yl)propanoic Acids as New Indole-Based Cytosolic Phospholipase A2α Inhibitors
2014
Design and Synthesis of Activity Probes for Glycosidases
2002
Asymmetric Ylide Reactions: Epoxidation, Cyclopropanation, Aziridination, Olefination, and Rearrangement
1997
Carbon−Carbon Coupling Reactions Catalyzed by Heterogeneous Palladium Catalysts
2006 Standout
Stereoselective Total Syntheses and Reassignment of Stereochemistry of the Freshwater Cyanobacterial Hepatotoxins Cylindrospermopsin and 7-Epicylindrospermopsin
2002
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Supramolecular Chirality in Self-Assembled Systems
2015 Standout
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Synthesis and Properties of an Aggregating Heterocyclic Helicene
2001
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
New calcineurin inhibiting 3-dimethylaminopropyl substituted diarylheterocycles by sonogashira reactions and catalytic hydrogenation
2005
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Anhydrous ferric chloride dispersed on silica gel induced ring enlargement of tertiary cycloalkanols. II : a convenient homologation of cycloalkanones, preparation of spiro systems and propella -γ-lactones
1985
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Synthesis of Molybdenum(VI) Monoimido Alkyl and Alkylidene Complexes
2005 StandoutNobel
Stannylcupration of Acetylenes Followed by Reaction with Epoxides: A Novel Annulation Strategy for the Synthesis of Cyclobutenes
1998
Selected Patented Cross-Coupling Reaction Technologies
2006 Standout
Stereoselective Cyclopropanation Reactions
2003 Standout
Fluorinated Ylides and Related Compounds
1996
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Antithetic regulation by β-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway β-agonist paradox
2003 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Chemoselective Elaboration of O-Linked Glycopeptide Mimetics by Alkylation of 3-ThioGalNAc
2001 StandoutNobel
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Solution phase combinatorial synthesis of arylpiperazines
1997
The maximal affinity of ligands
1999
Alternative Synthetic Methods through New Developments in Catalysis by Gold
2008 Standout
Synthesis and Conformational Study of 3-Hydroxy-4-(Hydroxymethyl)-1-Cyclohexanyl Purines and Pyrimidines
1997
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
SN2′ Substitutions of 1,3-Dichloropropenes with the Functionalized Copper-Zinc Reagents RCu(CN)ZnX
1990
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
The selectivity of protein kinase inhibitors: a further update
2007 Standout
Reconstitution of Apo-Glucose Dehydrogenase on Pyrroloquinoline Quinone-Functionalized Au Nanoparticles Yields an Electrically Contacted Biocatalyst
2005
Fluorinated organometallics: Perfluoroalkyl and functionalized perfluoroalkyl organometallic reagents in organic synthesis
1992
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Synthesis of monofluoro- and difluoro- methylenephosphonate analogues of sn-glycerol-3-phosphate as substrates for glycerol-3-phosphate dehydrogenase and the X-ray structure of the fluoromethylenephosphonate moiety
1996
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
Multicomponent reactions of allenes, diaryl diselenides, and nucleophiles in the presence of iodosobenzene diacetate: direct synthesis of 3-functionalized-2-arylselenyl substituted allyl derivatives
2007
Some Typical Advances in the Synthetic Applications of Allenes
2005 Standout
Rapid microscale synthesis: Solution phase parallel synthesis of a library of piperazines and piperidines using a water soluble base
1998
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Asymmetric Transition Metal-Catalyzed Allylic Alkylations
1996 Standout
Nickel-catalysed couplings of aryl chlorides with secondary amines and piperazines
1999
Applied Hydroformylation
2012 Standout
CC-1065 and the Duocarmycins: Synthetic Studies
1997
Aryl Amidation Routes to Dihydropyrrolo[3,2-e]indoles and Pyrrolo[3,2-f]tetrahydroquinolines: Total Synthesis of the (±)-CC-1065 CPI Subunit
2006
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Sequential mono-N-arylation of piperazine nitrogens. Part 1: A simplified method and its application to the preparation of a key N,N′-biaryl piperazine antifungal intermediate
1999
Synthesis of N-arylpiperazines from aryl halides and piperazine under a palladium tri-tert-butylphosphine catalyst
1998
Works of Serge Halazy being referenced
F 11356, a Novel 5-Hydroxytryptamine (5-HT) Derivative with Potent, Selective, and Unique High Intrinsic Activity at 5-HT1B/1D Receptors in Models Relevant to Migraine
1999
Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin: potent agonists for 5-HT1D receptors
1995
Dimerization of 8-OH-DPAT increases activity at serotonin 5-HT1A receptors
1998
(Aryloxy)methylsilane Derivatives as New Cholesterol Biosynthesis Inhibitors: Synthesis and Hypocholesterolemic Activity of a New Class of Squalene Epoxidase Inhibitors
1995
Dimerization of sumatriptan as an efficient way to design a potent, centrally and orally active 5-HT1B agonist
1998
Regio and stereoselective synthesis of 1-methylseleno-1-vinyl and 1-phenylseleno-1-vinyl cyclopropanes
1981
Studies on the synthesis of the antitumor agent CC-1065. Synthesis of PDE I and PDE II, inhibitors of cyclic adenosine-3',5'-monophosphate phosphodiesterase using the 3,3'-bipyrrole strategy
1987
Design and Synthesis of the First Generation of Novel Potent, Selective, and in Vivo Active (Benzothiazol-2-yl)acetonitrile Inhibitors of the c-Jun N-Terminal Kinase
2005
1,1-Difluoroalkyl glucosides: a new class of enzyme-activated irreversible inhibitors of .alpha.-glucosidases
1989
Studies Towards the Synthesis of the Saturated and Unsaturated Carbocyclic Methylene Phosphonate Analogs of Dideoxyadenosine
1993
Ortho- and para-(difluoromethyl)aryl-β-d-glucosides: A new class of enzyme-activated irreversible inhibitors of β-glucosidases
1990
Serotonin Dimers: Application of the Bivalent Ligand Approach to the Design of New Potent and Selective 5-HT1B/1D Agonists
1996
ChemInform Abstract: 9‐(Difluorophosphonoalkyl)guanines as a New Class of Multisubstrate Analogue Inhibitors of Purine Nucleoside Phosphorylase.
1991
9-(Difluorophosphonoalkyl)guanines as a new class of multisubstrate analog inhibitors of purine nucleoside phosphorylase
1991
Design, Synthesis, and Biological Activity of Novel, Potent, and Selective (Benzoylaminomethyl)thiophene Sulfonamide Inhibitors of c-Jun-N-Terminal Kinase
2004
Original Syntheses of Epoxides Involving Organoselenium Intermediates
1989
New reactions of 1-seleno-1-vinyl cyclopropanes
1981
Signal Transduction: An Exciting Field of Investigation for Small Molecule Drug Discovery
2003
Cyclopropanone diselenoketals interesting building blocks in organic synthesis
1978
New rearrangement of the adducts formed from allenes and benzeneselenenyl halides
1983
Synthesis of arylpiperazines via nucleophilic aromatic substitution of (η6-fluoroarene)tricarbonylchromium complexes
1996
Synthesis, binding affinity and intrinsic activity of new anilide derivatives of serotonin at human 5-HT1D receptors
1997
Fluorophosphonate derivatives of N9-benzylguanine as potent, slow-binding multisubstrate analogue inhibitors of purine nucleoside phosphorylase
1996
G-protein coupled receptors bivalent ligands and drug design
1999
F-11356
1999
Differentiation between Partial Agonists and Neutral 5-HT1BAntagonists by Chemical Modulation of 3-[3-(N,N-Dimethylamino)propyl]-4-hydroxy-N-[4-(pyridin-4-yl)phenyl]benzamide (GR-55562)
1997
Synthesis and Antiviral Properties of New Cycloalkanol Derivatives of Guanine
1992
Short and stereoselective synthesis of δ-functionalized E-α,α-difluoroallylphosphonates
1992
Selenium-stabilized carbocations. Formation of 2-(phenylseleno)allyl cations and their reactions with furan, pyrrole, and thiophene
1983
Studies on the antitumor agent CC-1065
1985
Efficient regioselective syntheses of α and β cuparenones. A new approach for the construction of the cyclopentane ring
1982
Studies on the antitumor agent CC-1065
1984
α-Selenocyclobutyllithium as a 2-lithio-1,3-diene equivalent. regioselective (100%) synthesis of ipsenol
1980
An Efficient Approach to the Synthesis of a Key Precursor of Mammalian Squalene Epoxidase Inhibitors Using a New Method for Transforming Aryl Bromides to Phenols
1995
Carbocyclic phosphonate analogs of 2′,3′-dideoxyadenosine-5′-monophosphate as substrates of 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetate
1992