Standout Papers
Citation Impact
Citing Papers
Aristolochic acid and the etiology of endemic (Balkan) nephropathy
2007 Standout
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
2009 Standout
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
2009
Prevalence of the Metabolic Syndrome in Individuals with Hyperuricemia
2007
Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study
2012
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
The xc− cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance
2008
Identification of a New Urate and High Affinity Nicotinate Transporter, hOAT10 (SLC22A13)
2008
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
2004
Role of monocarboxylate transporters in human cancers: state of the art
2012
Gout: On the brink of novel therapeutic options for an ancient disease
2004
Immunocytochemical characterization of the incubated rat renal cortical slices
2005
Pathophysiology of uric acid nephrolithiasis
2002
Impaired Organic Anion Transport in Kidney and Choroid Plexus of Organic Anion Transporter 3 (Oat3 (Slc22a8)) Knockout Mice
2002
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Protein Kinase C Activation Downregulates Human Organic Anion Transporter 1-Mediated Transport through Carrier Internalization
2003
Kidney stones: pathophysiology and medical management
2006 Standout
Introduction: P2 Receptors
2004
Uric Acid Causes Vascular Smooth Muscle Cell Proliferation by Entering Cells via a Functional Urate Transporter
2005
Novel insights into the pathogenesis of uric acid nephrolithiasis
2004
Cancer cells release glutamate via the cystine/glutamate antiporter
2009
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney
2002
Mouse Reduced in Osteosclerosis Transporter Functions as an Organic Anion Transporter 3 and Is Localized at Abluminal Membrane of Blood-Brain Barrier
2004
Nucleotide signalling during inflammation
2014 StandoutNature
Transport of organic anions across the basolateral membrane of proximal tubule cells
2003
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
2003
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
1993 Standout
Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues
2009
CATs and HATs: the SLC7 family of amino acid transporters
2004
Multi-protein assemblies underlie the mesoscale organization of the plasma membrane
2014 StandoutNobel
The x cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases
2008
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
P2Y Receptors Present in the Native and Isolated Rat Glomerulus
2004
Human Organic Anion Transporter 3 (hOAT3) can Operate as an Exchanger and Mediate Secretory Urate Flux
2003
The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics
2008 Standout
Uric Acid and Cardiovascular Risk
2008 Standout
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Prevalence of the metabolic syndrome in patients with gout: The Third National Health and Nutrition Examination Survey
2007
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
Gout
2009 Standout
Dividing the large glycoside hydrolase family 13 into subfamilies: towards improved functional annotations of -amylase-related proteins
2006
Molekulare Grundlagen der primär-renalen Hyperurikämie
2007
Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients
2009
Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules
2004
The carbohydrate-active enzymes database (CAZy) in 2013
2013 Standout
Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans
2008
Identification of a Novel Gene and a Common Variant Associated with Uric Acid Nephrolithiasis in a Sardinian Genetic Isolate
2003
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Recent Molecular Advances in Mammalian Glutamine Transport
2001
Human Organic Anion Transporter hOAT1 Forms Homooligomers
2005
The serum urate-lowering impact of weight loss among men with a high cardiovascular risk profile: the Multiple Risk Factor Intervention Trial
2010
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Gout
2016 Standout
Expression of SLC2A9 Isoforms in the Kidney and Their Localization in Polarized Epithelial Cells
2014
Substrate Binding Tunes Conformational Flexibility and Kinetic Stability of an Amino Acid Antiporter
2009
High‐resolution melting analysis for the rapid detection of an intronic single nucleotide polymorphism in SLC22A12 in male patients with primary gout in China
2009
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.
1994 StandoutNobel
Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton
2013 Standout
In vivo stimulation of apical P2 receptors in collecting ducts: evidence for inhibition of sodium reabsorption
2005
Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles
2007
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Molecular and ionic mimicry and the transport of toxic metals
2004
In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1
2005
Physiology, structure, and regulation of the cloned organic anion transporters
2008
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease
2005
Cancer cell lines release glutamate into the extracellular environment
2009
Ochratoxin A: The Continuing Enigma
2005
Antifibrotic Effects of Aldosterone Receptor Blocker (Spironolactone) in Patients with Chronic Kidney Disease
2009
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis
2010
Plasma Urate and Risk of Parkinson's Disease
2007
Interleukin 1: the first interleukin
1990
Changes in expression of renal Oat1, Oat3 and Mrp2 in cisplatin-induced acute renal failure after treatment of JBP485 in rats
2012
Gout and the risk of type 2 diabetes among men with a high cardiovascular risk profile
2008
Nucleotide receptors as targets in the pharmacological enhancement of dermal wound healing
2011
Efficacy and Tolerability of Probenecid as Urate-lowering Therapy in Gout; Clinical Experience in High-prevalence Population
2013
Uricosuric Action of Losartan via the Inhibition of Urate Transporter 1 (URAT 1) in Hypertensive Patients
2008
Pericytes regulate the blood–brain barrier
2010 StandoutNature
Human Organic Anion Transporter 4 Is a Renal Apical Organic Anion/Dicarboxylate Exchanger in the Proximal Tubules
2004
Inherited Hyperuricemic Disorders
2004
Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Cα: Accelerating endocytosis of the transporter
2009
A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese
2004
Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans
2006
Clinical features and risk factors of postsurgical gout
2007
Uric acid nephrolithiasis
2007
Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.
2006
Localization of ocular P2Y2 receptor gene expression by in situ hybridization
2003
Hepatobiliary transport
2000
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
2001
Genetic Hypercalciuria
2005
Effect of oral vitamin C supplementation on serum uric acid: A meta‐analysis of randomized controlled trials
2011
Contribution of Organic Anion Transporter 3 (Slc22a8) to the Elimination of p-Aminohippuric Acid and Benzylpenicillin across the Blood-Brain Barrier
2003
Serum Concentrations of Uric Acid and the Metabolic Syndrome Among US Children and Adolescents
2007
Lipid mediators in membrane rafts are important determinants of human health and disease
2007
Age-Related Impairment of Synaptic Transmission But Normal Long-Term Potentiation in Transgenic Mice that Overexpress the Human APP695SWE Mutant Form of Amyloid Precursor Protein
2001
ATP-Dependent Paracrine Intercellular Communication in Cultured Bovine Corneal Endothelial Cells
2004
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.
1988
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
The P2Y(2) receptor agonist INS37217 stimulates RPE fluid transport in vitro and retinal reattachment in rat.
2002
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.
1993 StandoutNobel
Purinergic Signaling and Vascular Cell Proliferation and Death
2002
The amino acid transport system bo,+and cystinuria
2001
Use-Dependent Effects of Amyloidogenic Fragments of β-Amyloid Precursor Protein on Synaptic Plasticity in Rat HippocampusIn Vivo
2001
Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity.
2003
Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+gradient
2003
β-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or β-amyloid deposits
2006
Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones
1991 StandoutScience
Dietary Folic Acid Promotes Survival of Foxp3+ Regulatory T Cells in the Colon
2012 StandoutNobel
Characterization of Monocarboxylate Transport in Human Kidney HK-2 Cells
2006
Multiple organic anion transporters contribute to net renal excretion of uric acid
2008
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ.
1990 StandoutNobel
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
Physiology and pharmacological role of the blood-brain barrier.
2009
Pathogenesis of Gout
2005
Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes.
1989 StandoutNobel
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
The Molecular Physiology of Uric Acid Homeostasis
2014
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Gout
2021 Standout
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
NPT1/SLC17A1 Is a Renal Urate Exporter in Humans and Its Common Gain‐of‐Function Variant Decreases the Risk of Renal Underexcretion Gout
2014
Heteromeric amino acid transporters: biochemistry, genetics, and physiology
2001
CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
2010 StandoutNobel
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
2002
PRIM: Proximity imaging of green fluorescent protein-tagged polypeptides
1998 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease?
2003 Standout
Organization of β-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes
2007 StandoutNobel
Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3
2011
Uric acid transporters hiding in the intestine
2016
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Seok Ho being referenced
The Human T-Type Amino Acid Transporter-1: Characterization, Gene Organization, and Chromosomal Location
2002
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
2002 StandoutNature
Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells
2001
Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports d-serine with high affinity
2000
Characterization of mouse organic anion transporter 5 as a renal steroid sulfate transporter
2005
Human cystinuria-related transporter: Localization and functional characterization
2001
Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney
2000
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver
1998
Functional Characterization of Rat Organic Anion Transporter 5 (Slc22a19) at the Apical Membrane of Renal Proximal Tubules
2005
Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain
1999
Human Organic Anion Transporters and Human Organic Cation Transporters Mediate Renal Antiviral Transport
2002
Characterization of Methotrexate Transport and Its Drug Interactions with Human Organic Anion Transporters
2002
Evidence for Cyclooxygenase‐1 Association with Caveolin‐1 and ‐2 in Cultured Human Embryonic Kidney (HEK 293) Cells
2004
Human Organic Anion Transporters Mediate the Transport of Tetracycline
2002
Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney
2005
Hydrogen peroxide downregulates human organic anion transporters in the basolateral membrane of the proximal tubule
2000
Role of Organic Anion Transporters in the Tubular Transport of Indoxyl Sulfate and the Induction of its Nephrotoxicity
2002
Transport Properties of a System y+L Neutral and Basic Amino Acid Transporter
2000
Evidence for Rat Organic Anion Transporter 3 Association with Caveolin‐1 in Rat Kidney
2005
Role of human organic anion transporter 4 in the transport of ochratoxin A
2002
Interaction of Human Organic Anion Transporters 2 and 4 with Organic Anion Transport Inhibitors
2002
Immunolocalization of Multispecific Organic Anion Transporters, OAT1, OAT2, and OAT3, in Rat Kidney
2002
Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino Acids
2000
Effect of low-dose dual blockade of renin–angiotensin system on urinary TGF-β in type 2 diabetic patients with advanced kidney disease
2005
Characterization of ochratoxin A transport by human organic anion transporters
2001
Molecular Identification of a Novel Carnitine Transporter Specific to Human Testis
2002
Expression of a system L neutral amino acid transporter at the blood–brain barrier
2000
Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter
1998
P2 purinoceptor localization along rat nephron and evidence suggesting existence of subtypes P2Y1and P2Y2
1998
Interleukin 1-mediated activation of interleukin 4 (IL 4)-producing T lymphocytes. Proliferation by IL 4-dependent and IL 4-independent mechanisms.
1987
Expression Cloning of a Na+-independent Aromatic Amino Acid Transporter with Structural Similarity to H+/Monocarboxylate Transporters
2001
Identification and Characterization of Human Organic Anion Transporter 3 Expressing Predominantly in the Kidney
2001
Purinoceptor-Mediated Calcium Mobilization and Cellular Proliferation in Cultured Bovine Corneal Endothelial Cells
2000
Rat Multispecific Organic Anion Transporter 1 (rOAT1) Transports Zidovudine, Acyclovir, and Other Antiviral Nucleoside Analogs
2000
Evidence for Cyclooxygenase-2 Association with Caveolin-3 in Primary Cultured Rat Chondrocytes
2006
Carboxyl‐terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity
2000
Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta
2000