Standout Papers
Citation Impact
Citing Papers
Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis
2008
Chitinase and Fizz Family Members Are a Generalized Feature of Nematode Infection with Selective Upregulation of Ym1 and Fizz1 by Antigen-Presenting Cells
2004
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
2010
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
2006
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
2007
Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent
2010
Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
2015 Science
The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis
2009
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Myofibroblasts and mechano-regulation of connective tissue remodelling
2002 Standout
Chemokines and Their Receptors Are Key Players in the Orchestra That Regulates Wound Healing
2013
Disclosure of the Culprits: Macrophages—Versatile Regulators of Wound Healing
2013
Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin‐Positive Intradermal Progenitors
2014
IL-17A-Expressing T Cells Are Essential for Bacterial Clearance in a Murine Model of Hypersensitivity Pneumonitis
2009
Alternative Activation Is an Innate Response to Injury That Requires CD4+ T Cells to be Sustained during Chronic Infection
2007 StandoutNobel
IL-13 Is Pivotal in the Fibro-Obliterative Process of Bronchiolitis Obliterans Syndrome
2007
IL-33 Induces IL-13–Dependent Cutaneous Fibrosis
2009
Methylation determines fibroblast activation and fibrogenesis in the kidney
2010
The Alzheimer's disease–protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool
2017
Hallmarks of Cancer: The Next Generation
2011 Standout
Focal Adhesion Kinase (FAK)-related Non-kinase Inhibits Myofibroblast Differentiation through Differential MAPK Activation in a FAK-dependent Manner
2008
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Monocyte Chemotactic Protein–1 As A Chemoattractant for Human Hepatic Stellate Cells
1999
Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis.
1996
Cutaneous Wound Healing
1999 Standout
Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis
1999
Transforming Growth Factor β as a Predictor of Liver and Lung Fibrosis after Autologous Bone Marrow Transplantation for Advanced Breast Cancer
1993
Inflammation and cancer
2002 StandoutNature
Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis
2001 Standout
Signal Transduction by the Chemokine Receptor CXCR3
2001
The IL-21 receptor augments Th2 effector function and alternative macrophage activation
2006
Thy-1 Promoter Hypermethylation
2008
Prominin-1/CD133 + Lung Epithelial Progenitors Protect from Bleomycin-induced Pulmonary Fibrosis
2009
Potential cellular and molecular causes of hypertrophic scar formation
2008
MIP-1alpha as a critical macrophage chemoattractant in murine wound repair.
1998
WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
2009
Glomerular matrix accumulation is linked to inhibition of the plasmin protease system
1992
Transforming Growth Factor β Suppresses Human Telomerase Reverse Transcriptase (hTERT) by Smad3 Interactions with c-Myc and the hTERT Gene
2006
Expression and regulation of monocyte chemoattractant protein‐1 by human eosinophils
1997
Cellular and molecular mechanisms of fibrosis
2007 Standout
Natural Killer T (NKT) Cells Attenuate Bleomycin-Induced Pulmonary Fibrosis by Producing Interferon-γ
2005
Glucocorticoid-regulated gene expression during cutaneous wound repair
2000
The Effect of Dietary Supplementation with n—3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells
1989 Standout
Transforming growth factor-beta in disease: the dark side of tissue repair.
1992
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats
2006
Effect of mast cell–derived mediators and mast cell–related neutral proteases on human dermal fibroblast proliferation and type I collagen production
2000
SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis
2009
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
2009
Factor Xa: at the crossroads between coagulation and signaling in physiology and disease
2008
Murine models of pulmonary fibrosis
2007
PPAR-γ Ligands Repress TGFβ-Induced Myofibroblast Differentiation by Targeting the PI3K/Akt Pathway: Implications for Therapy of Fibrosis
2011
PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis
2005
Pioglitazone, a Peroxisome Proliferator-Activated Receptor Gamma Ligand, Suppresses Bleomycin-Induced Acute Lung Injury and Fibrosis
2008
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
2009 Standout
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
2007
ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR α IN THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY
2005
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2
2000 StandoutNobel
Molecular Phenotypes Distinguish Patients with Relatively Stable from Progressive Idiopathic Pulmonary Fibrosis (IPF)
2009
Mechanotransduction and extracellular matrix homeostasis
2014 Standout
Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary Fibrosis
2009
IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis
2011
Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice.
1997
Lysyl oxidases: A novel multifunctional amine oxidase family
2001
Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis
2009
The fibroblast: Sentinel cell and local immune modulator in tumor tissue
2003
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Influence of Alternatively and Classically Activated Macrophages on Fibrogenic Activities of Human Fibroblasts
2000
Macrophages: Master Regulators of Inflammation and Fibrosis
2010 Standout
Idiopathic Pulmonary Fibrosis: Aberrant Recapitulation of Developmental Programs?
2008
Therapeutic strategies against TGF‐β signaling pathway in hepatic fibrosis
2005
Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface.
1992
Systemic sclerosis
2017 Standout
CD4+CD25+Foxp3+ regulatory T cells suppress cardiac fibrosis in the hypertensive heart
2011
Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages
2009
CCR2-Mediated Recruitment of Fibrocytes to the Alveolar Space after Fibrotic Injury
2005
Dexamethasone Is a Novel Potent Inducer of Connective Tissue Growth Factor Expression
1998
The myofibroblast: Paradigm for a mechanically active cell
2009
The Role of Growth Factors in Wound Healing
1996
Monocyte Chemoattractant Protein-1 mRNA Expression in the Human Burn Wound
1997
Expression of TNF and the Necessity of TNF Receptors in Bleomycin-Induced Lung Injury in Mice
1998
Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC
2006
Genetics of fibrosing lung diseases
2005
A novel model to study renal myofibroblast formation in vitro
2001
Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis
2006
Keratinocyte-derived growth factors play a role in the formation of hypertrophic scars
2001
Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica
1993
Transforming Growth Factors β1, β2, and β3 and Their Receptors Are Differentially Regulated during Normal and Impaired Wound Healing
1996
Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.
1995
Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis
2008
Obligatory Role for Interleukin-13 in Obstructive Lesion Development in Airway Allografts
2006
Fibrotic disease and the TH1/TH2 paradigm
2004 Standout
Fibroblast Differentiation in Wound Healing and Fibrosis
2007
The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis
1995
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes
2011
Prostaglandin F2α receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-β
2009
Extracellular BMP-antagonist regulation in development and disease: tied up in knots
2010
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
1999
Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.
1997
Corneal myofibroblast generation from bone marrow-derived cells
2010
Identification of Spontaneous Feline Idiopathic Pulmonary Fibrosis
2004
Human Monocyte Chemoattractant Protein-1 (MCP-1)
1991
The role of CXC chemokines in pulmonary fibrosis
2007
Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2
2008
Transfer of granulocyte-macrophage colony-stimulating factor gene to rat lung induces eosinophilia, monocytosis, and fibrotic reactions.
1996
The mechanical memory of lung myofibroblasts
2012
Induction of Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells by Transforming Growth Factor-β1
2005
Identification of Markers that Distinguish Monocyte-Derived Fibrocytes from Monocytes, Macrophages, and Fibroblasts
2009
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury
2009
Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.
1989 Standout
Fibroblasts and myofibroblasts in wound healing
2014 Standout
Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression
2009
Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis.
1991
Pushing Back: Wound Mechanotransduction in Repair and Regeneration
2011
MCP-1 mRNA Expression in Basal Keratinocytes of Psoriatic Lesions
1993
Tissue stiffness, latent TGF-β1 Activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis
2009
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Expression and location of Smad2, 4 mRNAs during and after liver fibrogenesis of rats
2006
Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4
2010
Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis
2004 Standout
Atherosclerosis — An Inflammatory Disease
1999 Standout
Erythromycin Suppresses Nuclear Factor-κB and Activator Protein-1 Activation in Human Bronchial Epithelial Cells
2000 StandoutNobel
Scarless wound healing: finding the right cells and signals
2016
WNT5A Is a Regulator of Fibroblast Proliferation and Resistance to Apoptosis
2009
Mechanisms of Myofibroblast Activity and Phenotypic Modulation
1999
Bone Morphogenetic Protein-4 Inhibitor Gremlin Is Overexpressed in Idiopathic Pulmonary Fibrosis
2006
Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis.
1992
Monocyte chemoattractant protein-1 in human atheromatous plaques.
1991
Smooth Muscle α-Actin Deficiency in Myofibroblasts Leads to Enhanced Renal Tissue Fibrosis
2006
Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts
1998
Thy1 (+) and (-) lung fibrosis subpopulations in LEW and F344 rats
1994
IgG4-related disease
2014 Standout
Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts
2000
Transforming Growth Factor β in Tissue Fibrosis
1994 Standout
Diminished Prostaglandin E 2 Contributes to the Apoptosis Paradox in Idiopathic Pulmonary Fibrosis
2010
Cutaneous changes of nephrogenic systemic fibrosis: Predictor of early mortality and association with gadolinium exposure
2007
Thrombin Differentiates Normal Lung Fibroblasts to a Myofibroblast Phenotype via the Proteolytically Activated Receptor-1 and a Protein Kinase C-dependent Pathway
2001
A Definition of Advanced Types of Atherosclerotic Lesions and a Histological Classification of Atherosclerosis
1995 Standout
Human monocyte chemoattractant protein-1 (MCP-1)
1990
Characterization of Human Renal Fibroblasts in Health and Disease: II. In Vitro Growth, Differentiation, and Collagen Synthesis of Fibroblasts From Kidneys With Interstitial Fibrosis
1991
Idiopathic pulmonary fibrosis
2011 Standout
Fibroblasts in cancer
2006 Standout
Adult familial cryptogenic fibrosing alveolitis in the United Kingdom
2000
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.
1995
Evolving Concepts of Apoptosis in Idiopathic Pulmonary Fibrosis
2006
Keratinocyte-Derived Monocyte Chemoattractant Protein 1 (MCP-1): Analysis in a Transgenic Model Demonstrates MCP-1 Can Recruit Dendritic and Langerhans Cells to Skin
1995
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Effects of Extracellular ATP on Mononuclear Phagocytes
1990
Growth factors in wound healing
1994
Stem Cells and Cell Therapies in Lung Biology and Lung Diseases
2008
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-β1-dependent mechanism in vitro
2001
Wound Healing in MIP-1α−/− and MCP-1−/− Mice
2001
The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice
2010
Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation
2000
Large and Sustained Induction of Chemokines during Impaired Wound Healing in the Genetically Diabetic Mouse: Prolonged Persistence of Neutrophils and Macrophages during the Late Phase of Repair
2000
TNF-α Suppresses α-Smooth Muscle Actin Expression in Human Dermal Fibroblasts: An Implication for Abnormal Wound Healing
2007
Upregulation of the p75 But Not the p55 TNF- α Receptor mRNA after Silica and Bleomycin Exposure and Protection from Lung Injury in Double Receptor Knockout Mice
1999
Future Research Directions in Idiopathic Pulmonary Fibrosis
2002
Prostaglandin-E 2 Counteracts Interleukin-1 β –Stimulated Upregulation of Platelet-Derived Growth Factor α -Receptor on Rat Pulmonary Myofibroblasts
1999
Interaction of IL-13 and C10 in the Pathogenesis of Bleomycin-Induced Pulmonary Fibrosis
2002
Interleukin-1β Causes Pulmonary Inflammation, Emphysema, and Airway Remodeling in the Adult Murine Lung
2005
Macrophage Inflammatory Proteins 1 and 2: Expression by Rat Alveolar Macrophages, Fibroblasts, and Epithelial Cells and in Rat Lung after Mineral Dust Exposure
1993
Endothelin-1 and Transforming Growth Factor-β1 Independently Induce Fibroblast Resistance to Apoptosis via AKT Activation
2009
Extracellular Regulation of Interleukin (IL)-1 β through Lung Epithelial Cells and Defective IL-1 Type II Receptor Expression
1999
The Role of CCL12 in the Recruitment of Fibrocytes and Lung Fibrosis
2006
Eosinophil-associated TGF- β 1 mRNA Expression and Airways Fibrosis in Bronchial Asthma
1997
A Role for Hyaluronan in Macrophage Accumulation and Collagen Deposition after Bleomycin-Induced Lung Injury
2000
Erythromycin Modulates IL-8 Expression in Normal and Inflamed Human Bronchial Epithelial Cells
1997
CXCL11 Attenuates Bleomycin-induced Pulmonary Fibrosis via Inhibition of Vascular Remodeling
2004
Fibroblasts from Idiopathic Pulmonary Fibrosis and Normal Lungs Differ in Growth Rate, Apoptosis, and Tissue Inhibitor of Metalloproteinases Expression
2001
Role of Myofibroblasts at the Invasion Front
2002
Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar.
1998
Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1
2001 Standout
Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells.
1992
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.
1989
The Antifibrogenic Potential of PPARγ Ligands in Pulmonary Fibrosis
2008
Matrix adhesion characteristics of corneal myofibroblasts.
1999
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Interleukin-13 and Its Receptors in Idiopathic Interstitial Pneumonia: Clinical Implications for Lung Function
2009
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.
1991 Standout
Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis
2004 Standout
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
2007
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Chemokines in cutaneous wound healing
2001
Inhibition of T cell recruitment and cutaneous delayed-type hypersensitivity-induced inflammation with antibodies to monocyte chemoattractant protein-1.
1996
Potential Therapeutic Targets for Cardiac Fibrosis
2010
Temporal expression of autocrine growth factors corresponds to morphological features of mesangial proliferation in Habu snake venom-induced glomerulonephritis.
1993
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
2011
Mechanisms of Pulmonary Fibrosis
2004
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
Possible Mechanisms of Bleomycin-Induced Fibrosis
1990
Mechanisms of Fibrogenesis
2008
Identification and characterization of a fibroblast marker: FSP1.
1995
Overexpression of granulocyte-macrophage colony-stimulating factor induces pulmonary granulation tissue formation and fibrosis by induction of transforming growth factor-beta 1 and myofibroblast accumulation.
1997
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
1980 StandoutNatureNobel
Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis.
1992
Whole animal knockout of smooth muscle alpha‐actin does not alter excisional wound healing or the fibroblast‐to‐myofibroblast transition
2012
Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-κB and AP-1
2002
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
β-Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix
2011 StandoutNobel
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
2003 Standout
Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo
1998
Stimulation of collagen α1(I) gene expression is associated with lipid peroxidation in hepatocellular injury: A link to tissue fibrosis?†
1994
Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 alpha by inflammatory granuloma fibroblasts.
1994
The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure
2002
Interstitial fibrosis and growth factors.
2000
Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans
2002
Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites
2001
The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family*
1999
Requirement of Mip-1α for an Inflammatory Response to Viral Infection
1995 StandoutScienceNobel
Pivotal Role of CCR1-Positive Leukocytes in Bleomycin- Induced Lung Fibrosis in Mice
2000
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Neutralization of the CXC Chemokine, Macrophage Inflammatory Protein-2, Attenuates Bleomycin-Induced Pulmonary Fibrosis
1999
Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.
1991
Innate Immune Responses to Lung-Stage Helminth Infection Induce Alternatively Activated Alveolar Macrophages
2006
Macrophages, Endothelial Cells, and Lipoprotein Oxidation in the Pathogenesis of Atherosclerosis*
1990
Modulation of JE/MCP-1 expression in dermal wound repair.
1995
Fibroblast heterogeneity: more than skin deep
2004
Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice.
1993
Protection from Pulmonary Fibrosis in the Absence of CCR2 Signaling
2001
IL-4 and IL-13 induce myofibroblastic phenotype of human lung fibroblasts through c-Jun NH2-terminal kinase–dependent pathway
2001
Absence of Macrophage Inflammatory Protein-1α Prevents the Development of Blinding Herpes Stromal Keratitis
1998 StandoutNobel
Pivotal Advance: Th-1 cytokines inhibit, and Th-2 cytokines promote fibrocyte differentiation
2008
Wound Healing: A Cellular Perspective
2018 Standout
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage
1992 Standout
IFN-γ-Inducible Protein-10 Attenuates Bleomycin-Induced Pulmonary Fibrosis Via Inhibition of Angiogenesis
1999
Cooperative interaction of nuclear factor-kappa B- and cis-regulatory enhancer binding protein-like factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines.
1990
The Fibronectin Domain ED-A Is Crucial for Myofibroblastic Phenotype Induction by Transforming Growth Factor-β1
1998 Standout
Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice
2008
Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression.
1988
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Interactions of granulocytes with the lungs.
1984
Alveolar macrophage apoptosis and TNF-α, but not p53, expression correlate with murine response to bleomycin
1998
Transforming Growth Factor (TGF)-β1–producing Regulatory T Cells Induce Smad-mediated Interleukin 10 Secretion That Facilitates Coordinated Immunoregulatory Activity and Amelioration of TGF-β1–mediated Fibrosis
2003
Tracking the Elusive Fibrocyte: Identification and Characterization of Collagen‐Producing Hematopoietic Lineage Cells During Murine Wound Healing
2014
IL-13-Induced Chemokine Responses in the Lung: Role of CCR2 in the Pathogenesis of IL-13-Induced Inflammation and Remodeling
2002
Adrenomedullin, a Multifunctional Regulatory Peptide*
2000
Size determination of enzymes by radiation inactivation
1979
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts
2004
Th2-like immune response in radiation-induced lung fibrosis
2011
IL-12 attenuates bleomycin-induced pulmonary fibrosis
2001
Th17-Polarized Immune Response in a Murine Model of Hypersensitivity Pneumonitis and Lung Fibrosis
2009
Exceedingly small iron oxide nanoparticles as positive MRI contrast agents
2017 StandoutNobel
Integrin‐mediated stimulation of monocyte chemotactic protein‐1 expression
1997
New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis
2010
Activation of fibroblasts in cancer stroma
2010
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Integrating mechanisms of pulmonary fibrosis
2011 Standout
Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats
2001
Molecular Bases of the Acute Coronary Syndromes
1995 Standout
Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines
1994
Works of Sem H. Phan being referenced
Fibrosis research : methods and protocols
2005
Notch1 Signaling in FIZZ1 Induction of Myofibroblast Differentiation
2009
A Comparative Study of Pulmonary Fibrosis Induced by Bleomycin and an O2 Metabolite Producing Enzyme System
1983
Therapies for bleomycin induced lung fibrosis through regulation of TGF‐β1 induced collagen gene expression
2007
Role of Eotaxin-1 (CCL11) and CC Chemokine Receptor 3 (CCR3) in Bleomycin-Induced Lung Injury and Fibrosis
2005
Monocyte chemotactic protein gene expression by cytokine-treated human fibroblasts and endothelial cells
1989
Altered Production and Regulation of Monocyte Chemoattractant Protein-1 From Pulmonary Fibroblasts Isolated From Patients With Idiopathic Pulmonary Fibrosis
1993
Costimulation of Fibroblast Collagen and Transforming Growth Factor β1 Gene Expression by Monocyte Chemoattractant Protein-1 via Specific Receptors
1996
Increased Types I and III Collagen and Transforming Growth Factor-β1 mRNA and Protein in Hypertrophic Burn Scar
1995
Bone marrow–derived progenitor cells in pulmonary fibrosis
2004
Gender-Based Differences in Bleomycin-Induced Pulmonary Fibrosis
2005
Stimulation of rat endothelial cell transforming growth factor-beta production by bleomycin.
1991
Animal Models of Pulmonary Fibrosis
2005
Binding of leukotriene C4 to rat lung fibroblasts and stimulation of collagen synthesis in vitro
1988
LUNG INTERLEUKIN-4 GENE EXPRESSION IN A MURINE MODEL OF BLEOMYCIN-INDUCED PULMONARY FIBROSIS
2001
Glucocorticoid-induced down regulation of transforming growth factor-β1 in adult rat lung fibroblasts
1995
Biology of Fibroblasts and Myofibroblasts
2008
Analysis of renal fibrosis in a rabbit model of crescentic nephritis.
1988
Transforming growth factor-β1 increases lysyl oxidase enzyme activity and mRNA in rat aortic smooth muscle cells
1997
C-C chemokines: novel mediators of the profibrotic inflammatory response to bleomycin challenge.
1996
Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice
2007
Lung Cytokine Production in Bleomycin-Induced Pulmonary Fibrosis
1992
Regulation of α-smooth muscle actin gene expression in myofibroblast differentiation from rat lung fibroblasts
2001
Phenotypic Differences in Cytokine Responsiveness of Hypertrophic Scar Versus Normal Dermal Fibroblasts
1993
Lung interleukin-5 expression in murine bleomycin-induced pulmonary fibrosis.
1997
Epigenetic Regulation of Myofibroblast Differentiation by DNA Methylation
2010
New strategies for treatment of pulmonary fibrosis.
1995
Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
2005
CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis
2003
The Myofibroblast in Pulmonary Fibrosis*
2002
Recent Developments in Myofibroblast Biology
2012
Nephrogenic fibrosing dermopathy: a novel cutaneous fibrosing disorder in patients with renal failure
2003
The Myofibroblast as an Inflammatory Cell in Pulmonary Fibrosis
1999
Cytokines and Pulmonary Fibrosis
1996
New Insights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis: A Potential Role for Stem Cells in the Lung Parenchyma and Implications for Therapy
2007
Role of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFβ
2005
FIZZ1 Stimulation of Myofibroblast Differentiation
2004
The Myofibroblast
2007 Standout
Antiapoptotic effect of found in inflammatory zone (FIZZ)1 on mouse lung fibroblasts
2007
Telomerase Regulation of Myofibroblast Differentiation
2006
The Role of Strain Variation in Murine Bleomycin-lnduced Pulmonary Fibrosis 1, 2
1983
Protection from Pulmonary Fibrosis in Leukotriene-Deficient Mice
2002
Regulation of Telomerase Activity in Rat Lung Fibroblasts
2002
Bleomycin-induced Pulmonary Fibrosis in Rats: Biochemical Demonstration of Increased Rate of Collagen Synthesis 1, 2
1980
Bleomycin Regulation of Transforming Growth Factor- β mRNA in Rat Lung Fibroblasts
1992
Induction of Telomerase Activity in Fibroblasts from Bleomycin-Injured Lungs
2000
Inhibition of Myofibroblast Apoptosis by Transforming Growth Factor β 1
1999
Effect of the Beige Mutation on Bleomycin-induced Pulmonary Fibrosis in Mice 1, 2
1983
Pulmonary Fibroblast Expression of Interleukin-8: A Model for Alveolar Macrophage-derived Cytokine Networking
1991
Smad3 Mediates Transforming Growth Factor-β–Induced α-Smooth Muscle Actin Expression
2003
Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10)
2005
Expression of Monocyte Chemoattractant Protein-1 (MCP-1) by Rat Alveolar Macrophages during Chronic Lung Injury
1993
The Effects of the Nude (nu/nu) Mutation on Bleomycin-induced Pulmonary Fibrosis
1983
Role of the myofibroblast in pulmonary fibrosis.
1996
Secretion of monocyte chemotactic activity by alveolar macrophages.
1989
TNF and IL-6 mediate MIP-1alpha expression in bleomycin-induced lung injury.
1998
Bleomycin Binding Sites on Alveolar Macrophages
1990
Bone marrow–derived progenitor cells in pulmonary fibrosis
2004
Regulation of Found in Inflammatory Zone 1 Expression in Bleomycin-Induced Lung Fibrosis: Role of IL-4/IL-13 and Mediation via STAT-6
2004
Alveolar macrophage-derived cytokines induce monocyte chemoattractant protein-1 expression from human pulmonary type II-like epithelial cells
1991
The effects of bleomycin on alveolar macrophage growth factor secretion.
1989
Dual Roles of IL-4 in Lung Injury and Fibrosis
2003
The role of soluble factors in bleomycin-induced pulmonary fibrosis.
1982
Platelet enhancement of O2-. responses in stimulated human neutrophils. Identification of platelet factor as adenine nucleotide.
1988
Fibroblast phenotypes in pulmonary fibrosis.
2003
Type I collagen gene expression in human atherosclerosis. Localization to specific plaque regions.
1993
The development of bleomycin-induced pulmonary fibrosis in neutrophil-depleted and complement-depleted rats.
1981
Regulation of Macrophage-Derived Fibroblast Growth Factor Release by Arachidonate Metabolites
1987
Studies on cytochrome oxidase. Partial resolution of enzymes containing seven or six subunits, from yeast and beef heart, respectively.
1976
Regulation of lung fibroblast alpha-smooth muscle actin expression, contractile phenotype, and apoptosis by IL-1beta.
1997
The role of IL-5 in bleomycin-induced pulmonary fibrosis
1998
Eosinophils and T Lymphocytes Possess Distinct Roles in Bleomycin-Induced Lung Injury and Fibrosis
2003
TNF-alpha-mediated lung cytokine networking and eosinophil recruitment in pulmonary fibrosis.
1997
Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study.
1994
Cellular sensitivity to collagen in bleomycin-treated rats.
1982
Inhibition of bleomycin-induced pulmonary fibrosis by lipopolysaccharide.
1984
Monokine-induced Neutrophil Chemotactic Factor Gene Expression in Human Fibroblasts
1989
Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β
1989 Science
Analysis of alpha 1 (I) procollagen alpha 1 (IV) collagen, and beta-actin mRNA in glomerulus and cortex of rabbits with experimental anti-glomerular basement membrane disease. Evidence for early extraglomerular collagen biosynthesis.
1990
Expression and regulation of human pulmonary fibroblast-derived monocyte chemotactic peptide-1
1992
Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis.
1996
Cellular localization of transforming growth factor-beta expression in bleomycin-induced pulmonary fibrosis.
1995
Regulation of rat pulmonary artery endothelial cell transforming growth factor-beta production by IL-1 beta and tumor necrosis factor-alpha
1992
A Profibrotic Function of IL-12p40 in Experimental Pulmonary Fibrosis
2002
A role for C-C chemokines in fibrotic lung disease
1995
TNF and IL-6 mediate MIP-1α expression in bleomycin-induced lung injury
1998
Lung monocyte chemoattractant protein-1 gene expression in bleomycin-induced pulmonary fibrosis.
1994
Inhibition of bleomycin-induced pulmonary fibrosis by nordihydroguaiaretic acid. The role of alveolar macrophage activation and mediator production.
1986
Transforming growth factor-beta production in anti-glomerular basement membrane disease in the rabbit.
1991
Production and function of murine macrophage inflammatory protein-1 alpha in bleomycin-induced lung injury.
1994
Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli.
1984
Bleomycin-induced pulmonary fibrosis. Effects of steroid on lung collagen metabolism.
1981
PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis
2007
Prostaglandins as endogenous mediators of interleukin 1 production.
1986