Citation Impact
Citing Papers
Role of UEV-1, an Inactive Variant of the E2 UbiquitinConjugating Enzymes, in In Vitro Differentiation and Cell Cycle Behavior of HT-29-M6 Intestinal Mucosecretory Cells
1998 StandoutNobel
Oxidative Stress
2017 Standout
Lipid-gated monovalent ion fluxes regulate endocytic traffic and support immune surveillance
2019 Science
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
2015 Science
Microtubule motors control membrane dynamics of Salmonella-containing vacuoles
2004
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
2008
Identification of interferon-stimulated genes that attenuate Ebola virus infection
2020 StandoutNobel
Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells
2013
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
2020
Triple-Negative Breast Cancer
2010 Standout
Autophagy in infection, inflammation and immunity
2013 Standout
An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis
2020 StandoutNobel
Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
2015 Nature
mTOR Signaling in Growth Control and Disease
2012 Standout
Identification of a Region within the Ubiquitin-activating Enzyme Required for Nuclear Targeting and Phosphorylation
1997 StandoutNobel
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Targeting of Enteropathogenic Escherichia coli EspF to Host Mitochondria Is Essential for Bacterial Pathogenesis
2004
Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c
2012
Rapamycin induces pluripotent genes associated with avoidance of replicative senescence
2013
A Genome-Wide Screening in Saccharomyces cerevisiae for Genes That Confer Resistance to the Anticancer Agent Cisplatin
2000
The role of autophagy in neurodegenerative disease
2013 Standout
CIP2A is a target of bortezomib in human triple negative breast cancer cells
2012
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
The Ubiquitin-activating Enzyme E1 Is Phosphorylated and Localized to the Nucleus in a Cell Cycle-dependent Manner
1996 StandoutNobel
Hallmarks of aging: An expanding universe
2023 Standout
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
2005
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Ageing as a risk factor for neurodegenerative disease
2019 Standout
Autophagy and senescence, converging roles in pathophysiology as seen through mouse models
2021
System-wide Benefits of Intermeal Fasting by Autophagy
2017
The biology and function of fibroblasts in cancer
2016 Standout
High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy
2014 StandoutNobel
Molecular mechanisms of phagocytic uptake in mammalian cells
2008
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production
2012
Suppression of Autophagy in Osteocytes Mimics Skeletal Aging
2013
Redox homeostasis: The Golden Mean of healthy living
2016
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia
1999 StandoutNobel
Human Cancer Cells Harbor T-Stumps, a Distinct Class of Extremely Short Telomeres
2007 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Intracellular Toll-like Receptors
2010 StandoutNobel
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Regulation of innate immune cell function by mTOR
2015
M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
2007 Standout
Subversion of phosphoinositide metabolism by intracellular bacterial pathogens
2004
Bacterial Adhesion and Entry into Host Cells
2006
Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence
2013
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation
2011
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Autophagy maintains stemness by preventing senescence
2016 Nature
Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
1998
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
The Dark Side of the Salad: Salmonella typhimurium Overcomes the Innate Immune Response of Arabidopsis thaliana and Shows an Endopathogenic Lifestyle
2008 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Secretion of type III effectors into host cells in real time
2005
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of senescent cells in ageing
2014 StandoutNature
Senescence and the SASP: many therapeutic avenues
2020
The PI3K Pathway in Human Disease
2017 Standout
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
2011
Molecular mechanisms of Escherichia coli pathogenicity
2009
Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells
2013
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Manipulation of host-cell pathways by bacterial pathogens
2007 Nature
Cellular Senescence in Postmitotic Cells: Beyond Growth Arrest
2018
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
2011
Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model
2016
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium
2010 StandoutNobel
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Enteropathogenic and EnterohemorrhagicEscherichia coliInfections: Translocation, Translocation, Translocation
2005
Molecular Pathogenesis ofShigellaspp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion
2008
While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts
2017
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Lysosome-mediated processing of chromatin in senescence
2013
Ubiquitin-activating enzyme, e1, is phosphorylated in mammalian cells by the protein kinase cdc2
1995
A versatile drug delivery system targeting senescent cells
2018
Ebola Virus VP40 Drives the Formation of Virus-Like Filamentous Particles Along with GP
2002
Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins
2017
Rapamycin for longevity: opinion article
2019
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Mutant p53 Induces the GEF-H1 Oncogene, a Guanine Nucleotide Exchange Factor-H1 for RhoA, Resulting in Accelerated Cell Proliferation in Tumor Cells
2006
Regulation of TFEB and V-ATPases by mTORC1
2011
Spermidine in health and disease
2018 StandoutScience
GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA
2008
Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
2019
Intracellular survival of Shigella
2006
Wound Healing: A Cellular Perspective
2018 Standout
Mechanisms of Diabetic Complications
2013 Standout
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation
2013
Geometric cues for directing the differentiation of mesenchymal stem cells
2010 Standout
The life cycle of phagosomes: formation, maturation, and resolution
2016
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
The intricate regulation and complex functions of the Class III phosphoinositide 3-kinase Vps34
2016
mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin Ligases
2014
Works of Sei Yoshida being referenced
Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
2011 Science
Increased phosphorylation of Akt in triple‐negative breast cancers
2007
Shigella deliver an effector protein to trigger host microtubule destabilization, which promotes Rac1 activity and efficient bacterial internalization
2002
Exploiting host microtubule dynamics: a new aspect of bacterial invasion
2003
Shigella Invasion of Macrophage Requires the Insertion of IpaC into the Host Plasma Membrane
2001
Coordination of the Rab5 Cycle on Macropinosomes
2011
Conditional resistance to thymineless death predominantly selects DNA synthesis-deficient mutants of mammalian cells
1993
Redox Regulates Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity by Modulating the TSC1/TSC2-Rheb GTPase Pathway
2011
Enteropathogenic Escherichia coli activates the RhoA signaling pathway via the stimulation of GEF‐H1
2004
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
2011
Emerging role of autophagy in kidney function, diseases and aging
2012
Microtubule-Severing Activity of Shigella Is Pivotal for Intercellular Spreading
2006 Science
Growth factor signaling to mTORC1 by amino acid–laden macropinosomes
2015
Gains of 1q21-q22 and 13q12-q14 are potential indicators for resistance to cisplatin-based chemotherapy in ovarian cancer patients.
1999
Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages
2009