Standout Papers
- A 52‐kb deletion in the SOST‐MEOX1 intergenic region on 17q12‐q21 is associated with van Buchem disease in the Dutch population (2002)
- X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy (2001)
- A Novel Mutation in CD83 Results in the Development of a Unique Population of CD4+ T Cells (2004)
- Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics (2010)
- Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein (2001)
- Polymorphisms in the Sclerosteosis/van Buchem Disease Gene (SOST) Region Are Associated with Bone-Mineral Density in Elderly Whites (2004)
Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Bone Density Ligand, Sclerostin, Directly Interacts With LRP5 but Not LRP5G171V to Modulate Wnt Activity
2006
Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis
2008
Number of T Reg Cells That Differentiate Does Not Increase upon Encounter of Agonist Ligand on Thymic Epithelial Cells
2004
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
2021 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
2006 Standout
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
2005
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Nonredundant roles for Stat5a/b in directly regulating Foxp3
2007
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Regulatory T Cells Dynamically Control the Primary Immune Response to Foreign Antigen
2007
Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
2010
Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus
2009
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells
2007
Osteoporosis
2006
IFITm1 Is a Tight Junction Protein That Inhibits Hepatitis C Virus Entry
2012
Targeting the Wnt/β-Catenin Pathway to Regulate Bone Formation in the Adult Skeleton
2007
Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures
2010 StandoutNobel
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication
2013
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
2010 StandoutNobel
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
2002
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Secreted and Transmembrane Wnt Inhibitors and Activators
2012
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
FOXP3 acts as a rheostat of the immune response
2005
Porphyrias
2010 Standout
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
2005
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
2003 Standout
Osteoporosis: now and the future
2011 Standout
Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation
2013
SOST Is a Ligand for LRP5/LRP6 and a Wnt Signaling Inhibitor
2005
Hepatitis C virus and microRNAs: miRed in a host of possibilities
2014
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
2001 StandoutNobel
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
2005 StandoutNobel
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
2009
FOXP3 and scurfy: how it all began
2014 StandoutNobel
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
A forkhead-domain gene is mutated in a severe speech and language disorder
2001 Nature
An essential role for Scurfin in CD4+CD25+ T regulatory cells
2003 StandoutNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
2007 Nature
Foxp3: a genetic foundation for regulatory T cell differentiation and function
2020 StandoutNobel
Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
2011
Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4
2014 StandoutNobel
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
2004 StandoutNobel
LRP5 Mutations Linked to High Bone Mass Diseases Cause Reduced LRP5 Binding and Inhibition by SOST
2006
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
2007 Nature
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
2021 StandoutNobel
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
2010
Foxp3 and Natural Regulatory T Cells
2003 StandoutNobel
FOXP3+ regulatory T cells in the human immune system
2010 StandoutNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Chromosomal Redistribution of Male-Biased Genes in Mammalian Evolution with Two Bursts of Gene Gain on the X Chromosome
2010
Regulatory T cell development in the absence of functional Foxp3
2007
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
2020 StandoutNobel
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Molecular evolution of FOXP2, a gene involved in speech and language
2002 StandoutNatureNobel
Romosozumab Treatment in Postmenopausal Women with Osteoporosis
2016
Mechanisms of Anabolic Therapies for Osteoporosis
2007
FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT
2006
Update on Wnt signaling in bone cell biology and bone disease
2011
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis
2006 StandoutNobel
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation
2001 StandoutNobel
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
2006
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
2014
Naturally Arising CD4+Regulatory T Cells for Immunologic Self -Tolerance and Negative Control of Immune Responses
2003 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
FOXP3: Of Mice and Men
2005
Regulatory T Cells: Mechanisms of Differentiation and Function
2007 Standout
Roles of regulatory T cells in cancer immunity
2016
The origin of FOXP3-expressing CD4+ regulatory T cells: thymus or periphery
2003 StandoutNobel
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients
2006 StandoutNobel
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
2012
Viral Proteomics
2007
Blockade of CTLA-4 on CD4+CD25+ Regulatory T Cells Abrogates Their Function In Vivo
2006
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
2008
In Vivo Instruction of Suppressor Commitment in Naive T Cells
2004
Cytokine Storm
2020 Standout
LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling:Arrows point the way
2004
IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells
2004
Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation
2005 Standout
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The Amount of Scurfin Protein Determines Peripheral T Cell Number and Responsiveness
2001 StandoutNobel
Adaptive strategies of the influenza virus polymerase for replication in humans
2009 StandoutNobel
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Conditional stability of T cells
2010 StandoutNatureNobel
Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3
2003 Standout
A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge
2011
Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance
2012
CD25+ CD4+ T Cells, Expanded with Dendritic Cells Presenting a Single Autoantigenic Peptide, Suppress Autoimmune Diabetes
2004 StandoutNobel
Regulatory T Cells: Differentiation and Function
2016
Differentiation of Effector CD4 T Cell Populations
2010 Standout
Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis
2006 StandoutNobel
Works of Sean Proll being referenced
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers
2009
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
2001 StandoutNobel
Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein
2001 StandoutNobel
Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
2013
A 52‐kb deletion in the SOST‐MEOX1 intergenic region on 17q12‐q21 is associated with van Buchem disease in the Dutch population
2002 StandoutNobel
Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics
2010 StandoutNobel
Gene Expression Patterns That Correlate With Hepatitis C and Early Progression to Fibrosis in Liver Transplant Recipients
2006
Polymorphisms in the Sclerosteosis/van Buchem Disease Gene (SOST) Region Are Associated with Bone-Mineral Density in Elderly Whites
2004 StandoutNobel
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
2006 Nature
Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response
2006
Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection
2010
A Single-Amino-Acid Substitution in a Polymerase Protein of an H5N1 Influenza Virus Is Associated with Systemic Infection and Impaired T-Cell Activation in Mice
2009
Integrated Molecular Signature of Disease: Analysis of Influenza Virus-Infected Macaques through Functional Genomics and Proteomics
2006
Down-regulation of hepcidin in porphyria cutanea tarda
2008
Impaired Cholesterol Biosynthesis in a Neuronal Cell Line Persistently Infected with Measles Virus
2009
Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection
2009
Unique Signatures of Long Noncoding RNA Expression in Response to Virus Infection and Altered Innate Immune Signaling
2010