Citation Impact
Citing Papers
Smooth Muscle–Specific Deletion of Nitric Oxide–Sensitive Guanylyl Cyclase Is Sufficient to Induce Hypertension in Mice
2010
Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction
2007
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter
2006 StandoutNobel
Homologous desensitization of signalling by the alpha (α) isoform of the human thromboxane A2 receptor: A specific role for nitric oxide signalling
2007
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway
1996 Standout
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
2006 StandoutNobel
Specific Regulation of RGS2 Messenger RNA by Angiotensin II in Cultured Vascular Smooth Muscle Cells
2000
Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene
1998
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice
2009
G Protein-Coupled Receptor Kinase Function Is Essential for Chemosensation in C. elegans
2004 StandoutNobel
Endothelin-1-induced GLUT4 Translocation Is Mediated via Gαq/11 Protein and Phosphatidylinositol 3-Kinase in 3T3-L1 Adipocytes
1999
Heme oxygenase-1 overexpression exacerbates heart failure with aging and pressure overload but is protective against isoproterenol-induced cardiomyopathy in mice
2014
Hemizygosity at the NCF1 Gene in Patients with Williams-Beuren Syndrome Decreases Their Risk of Hypertension
2006
Cross-Talk between Gs- and Gq-Coupled Pathways in Regulation of Interleukin-4 by A2B Adenosine Receptors in Human Mast Cells
2006
Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ
2013 Standout
The Biology of Cyclic GMP-dependent Protein Kinases
2004
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
2016 StandoutNobel
cGMP Signalling in the Mammalian Brain: Role in Synaptic Plasticity and Behaviour
2008
Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets
2011
Antagonism between Goalpha and Gqalpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for Goalpha signaling and regulates Gqalpha activity
1999
cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity
2008
Hallmarks of aging: An expanding universe
2023 Standout
Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome
2008
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Probing the Interaction between the Coiled Coil Leucine Zipper of cGMP-dependent Protein Kinase Iα and the C Terminus of the Myosin Binding Subunit of the Myosin Light Chain Phosphatase
2008
Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family
1996 Nature
cGK Substrates
2008
Heterotrimeric G protein signaling: Role in asthma and allergic inflammation
2002
cGMP in the Vasculature
2008
Diagnosis and management of medical problems in adults with Williams–Beuren syndrome
2007
Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities
2012
Uric Acid and Cardiovascular Risk
2008 Standout
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
Cyclic GMP-dependent Protein Kinase Iα Inhibits Thrombin Receptor-mediated Calcium Mobilization in Vascular Smooth Muscle Cells
2006
Identification of the Interface between cGMP-dependent Protein Kinase Iβ and Its Interaction Partners TFII-I and IRAG Reveals a Common Interaction Motif
2005
dpl-1 DP and efl-1 E2F Act with lin-35 Rb to Antagonize Ras Signaling in C. elegans Vulval Development
2001 StandoutNobel
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
2011 StandoutNature
An Amino-terminal Amphipathic α-Helix Mediates Membrane Association of the Hepatitis C Virus Nonstructural Protein 5A
2002
cGMP Regulated Protein Kinases (cGK)
2008
G Protein-coupled Receptor Kinase 2/Gαq/11 Interaction
2003
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Williams–Beuren Syndrome
2010 Standout
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
2008 StandoutNature
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
2005 StandoutNobel
Local Presynaptic Activity Gates Homeostatic Changes in Presynaptic Function Driven by Dendritic BDNF Synthesis
2010
Regulation of RGS2 and Second Messenger Signaling in Vascular Smooth Muscle Cells by cGMP-dependent Protein Kinase
2007
Formin Homology Domain Protein (FHOD1) Is a Cyclic GMP-dependent Protein Kinase I-binding Protein and Substrate in Vascular Smooth Muscle Cells
2004
β-Arrestin-mediated Recruitment of the Src Family Kinase Yes Mediates Endothelin-1-stimulated Glucose Transport
2001 StandoutNobel
Distinct Subsets of Syt-IV/BDNF Vesicles Are Sorted to Axons versus Dendrites and Recruited to Synapses by Activity
2012 StandoutNobel
RGS16 Function Is Regulated by Epidermal Growth Factor Receptor-mediated Tyrosine Phosphorylation
2001
cGMP signals mainly through cAMP kinase in permeabilized murine aorta
2006
The Discovery and Development of Liraglutide and Semaglutide
2019
Endothelial Functions of Sphingosine-1-phosphate
2010
Inhibition of Gαq-dependent PLC-β1 activity by PKG and PKA is mediated by phosphorylation of RGS4 and GRK2
2006
Selective Regulation of Gαq/11 by an RGS Domain in the G Protein-coupled Receptor Kinase, GRK2
1999 Nobel
Rho and Rac Take Center Stage
2004 Standout
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Gas biology: small molecular medicine
2012 StandoutNobel
RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro
2000
Nitric oxide signaling in hypoxia
2012
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Seven-transmembrane receptors
2002 StandoutNobel
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
2006 Standout
RGS2 Is a Mediator of Nitric Oxide Action on Blood Pressure and Vasoconstrictor Signaling
2004
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits
1996 Nobel
Biomarkers in Heart Failure
2008 Standout
The ubiquitin system
2000 StandoutNobel
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Pressure-overload magnitude-dependence of the anti-hypertrophic efficacy of PDE5A inhibition
2008
Cell signalling diversity of the Gqα family of heterotrimeric G proteins
2005
IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation
2010
Recommendations for Blood Pressure Measurement in Humans and Experimental Animals
2004 Standout
Postsynaptic GluA1 enables acute retrograde enhancement of presynaptic function to coordinate adaptation to synaptic inactivity
2010
Heme Oxygenases in Cardiovascular Health and Disease
2016
Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine.
1995
Regulator of G Protein Signaling Proteins: Novel Multifunctional Drug Targets
2001
Structure, Function, and Control of Phosphoinositide-Specific Phospholipase C
2000
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Clinical Practice Guideline: The Diagnosis, Management, and Prevention of Bronchiolitis
2014 Standout
Once-Weekly Semaglutide in Adults with Overweight or Obesity
2021 Standout
Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging
2020
Rescue of cGMP Kinase I Knockout Mice by Smooth Muscle–Specific Expression of Either Isozyme
2007
ADP-Ribosylation Factor 6 Regulates Actin Cytoskeleton Remodeling in Coordination with Rac1 and RhoA
2000
Surfing the p53 network
2000 StandoutNature
The Regulator of G Protein Signaling Family
2000
G Alpha-q/11 Protein Plays a Key Role in Insulin-Induced Glucose Transport in 3T3-L1 Adipocytes
1999
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Regulation of T cell activation, anxiety, and male aggression by RGS2
2000
Nitroso–Redox Interactions in the Cardiovascular System
2006
Phosphodiesterase Type 5
2007
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
2000
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Leukemia-Associated Rho Guanine Nucleotide Exchange Factor Promotes Gαq-Coupled Activation of RhoA
2002
GTPase-Activating Proteins for Heterotrimeric G Proteins: Regulators of G Protein Signaling (RGS) and RGS-Like Proteins
2000
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
2005 StandoutNobel
G-protein-coupled Receptor (GPCR) Kinase Phosphorylation and β-Arrestin Recruitment Regulate the Constitutive Signaling Activity of the Human Cytomegalovirus US28 GPCR
2003 StandoutNobel
Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain
1997
Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaq.
2000
Role of Renal Angiotensin II Type 1 Receptors in the Genesis of Hypertension
2007 StandoutNobel
Works of Scott P. Heximer being referenced
β 2 -Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids
2011
Increased GABAB Receptor-Mediated Signaling Reduces the Susceptibility of Fragile X Knockout Mice to Audiogenic Seizures
2009
The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice
2017
Comparison of mRNA Expression of Two Regulators of G-Protein Signaling, RGS1/BL34/1R20 and RGS2/G0S8 , in Cultured Human Blood Mononuclear Cells
1997
Cyclosporin A Inhibits Early mRNA Expression of G0/G1 Switch Gene 2 ( G0S2 ) in Cultured Human Blood Mononuclear Cells
1997
A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells
1994
Mechanisms Governing Subcellular Localization and Function of Human RGS2
2001
Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency
2003
A Human Putative Lymphocyte G 0 /G 1 Switch Gene Homologous to a Rodent Gene Encoding a Zinc-Binding Potential Transcription Factor
1993
G Protein Selectivity Is a Determinant of RGS2 Function
1999
The RGS2 Gene Product from a Candidate Hypertension Allele Shows Decreased Plasma Membrane Association and Inhibition of Gq
2008
Genetic evidence for the requirement of adenylyl cyclase 1 in synaptic scaling of forebrain cortical neurons
2007
Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia
2011
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
2003
Role of Sphingosine-1-Phosphate Phosphohydrolase 1 in the Regulation of Resistance Artery Tone
2008
RGS4 Regulates Parasympathetic Signaling and Heart Rate Control in the Sinoatrial Node
2008
G-Protein Signaling Participates in the Development of Diabetic Cardiomyopathy
2004
Hypertension‐evoked RhoA activity in vascular smooth muscle cells requires RGS5
2017
Iron Overload Decreases Ca V 1.3-Dependent L-Type Ca 2+ Currents Leading to Bradycardia, Altered Electrical Conduction, and Atrial Fibrillation
2011
RGS2/G0S8 is a selective inhibitor of Gqα function
1997
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
2003
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
2003