Citation Impact
Citing Papers
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
2015 StandoutNobel
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development
2009
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
2016 StandoutScience
Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling
2009
Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b
2010
The Talpid3 gene ( KIAA0586 ) encodes a centrosomal protein that is essential for primary cilia formation
2009
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Rapid Identification of a Disease Allele in Mouse Through Whole Genome Sequencing and Bulk Segregation Analysis
2010 StandoutNobel
Cerebral cortex expansion and folding: what have we learned?
2016
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
Mutational pattern and frequency of induced nucleotide changes in mouse ENU mutagenesis
2007
Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis
2009
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Role of radial glial cells in cerebral cortex folding
2014
IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy
2007
Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons
2007
Hedgehog: functions and mechanisms
2008 Standout
Cell biological regulation of division fate in vertebrate neuroepithelial cells
2011
Hedgehog signalling: how to get from Smo to Ci and Gli
2006
Forces in Tissue Morphogenesis and Patterning
2013 Standout
Bardet-Biedl syndrome: an emerging pathomechanism of intracellular transport
2006
The nonmotile ciliopathies
2009
Assembly of primary cilia
2008
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
2019 StandoutNobel
Decoding the Hedgehog signal in animal development
2006
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology
2014
Organoids: Modeling Development and the Stem Cell Niche in a Dish
2016
The Graded Response to Sonic Hedgehog Depends on Cilia Architecture
2007
Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation
2012
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
The Human Transcription Factors
2018 Standout
Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
2015 StandoutNobel
Growth and folding of the mammalian cerebral cortex: from molecules to malformations
2014
GSK3 signalling in neural development
2010
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
2008
Intraflagellar transport, cilia, and mammalian Hedgehog signaling: Analysis in mouse embryonic fibroblasts
2008
Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo
2009
Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex
2013
Targeting the Hedgehog pathway in cancer
2006 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells
2008
Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms
2007
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Mechanically Activated Ion Channels
2015 StandoutNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
The Vertebrate Primary Cilium in Development, Homeostasis, and Disease
2009
Release and trafficking of lipid-linked morphogens
2005
Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective
2010
Cilia: Tuning in to the Cell's Antenna
2006
Dual and opposing roles of primary cilia in medulloblastoma development
2009
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
2009 Standout
Cortical Gyrification Induced by Fibroblast Growth Factor 2 in the Mouse Brain
2013
A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling
2009
The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development
2009
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
2011 Standout
Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism
2017 StandoutNobel
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
EMT: 2016
2016 Standout
The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning
2007
Hedgehog beyond medulloblastoma and basal cell carcinoma
2010
Transcriptional control of genes involved in ciliogenesis: a first step in making cilia
2010
Hippi is essential for node cilia assembly and Sonic hedgehog signaling
2006
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis
2007 Standout
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain
2009
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
COPII and the regulation of protein sorting in mammals
2011 StandoutNobel
Hedgehog Signaling in Development and Cancer
2008 Standout
Patching the gaps in Hedgehog signalling
2007
Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease
2010
Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse
2009
Intraflagellar Transport and Cilium-Based Signaling
2006
The Human Condition—A Molecular Approach
2014 StandoutNobel
The primary cilium: a signalling centre during vertebrate development
2010 Standout
Generation of cerebral organoids from human pluripotent stem cells
2014
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Development and Evolution of the Human Neocortex
2011
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
2012
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Modeling Development and Disease with Organoids
2016 Standout
Targeting of β-Arrestin2 to the Centrosome and Primary Cilium: Role in Cell Proliferation Control
2008
The Zn Finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis
2009
Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
2008
Mechanisms that regulate the number of neurons during mouse neocortical development
2010
Emerging roles of neural stem cells in cerebral cortex development and evolution
2012
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos
2008
The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation
2010
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
2005
The Cell Biology of Neurogenesis: Toward an Understanding of the Development and Evolution of the Neocortex
2014
ConditionalKif3aablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis
2007
The Organocatalytic Approach to Enantiopure 2H‐ and 3H‐Pyrroles: Inhibitors of the Hedgehog Signaling Pathway
2016 StandoutNobel
Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth
2012 StandoutNobel
Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia
2007
Switching on cilia: transcriptional networks regulating ciliogenesis
2014
Coordinated genomic control of ciliogenesis and cell movement by RFX2
2014
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Smoothened Signal Transduction Is Promoted by G Protein-Coupled Receptor Kinase 2
2006 StandoutNobel
Cilia and Developmental Signaling
2007
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Kinome siRNA Screen Identifies Regulators of Ciliogenesis and Hedgehog Signal Transduction
2008
Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia
2009
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
2009
Vascular remodeling of the mouse yolk sac requires hemodynamic force
2007
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Native Piezo2 Interactomics Identifies Pericentrin as a Novel Regulator of Piezo2 in Somatosensory Neurons
2016
What Determines Blood Vessel Structure? Genetic Prespecification vs. Hemodynamics
2006
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Neurogenesis at the Brain–Cerebrospinal Fluid Interface
2011
Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
2008
The Hedgehog Signaling Pathway in Cancer
2006
Ftm is a novel basal body protein of cilia involved in Shh signalling
2007
Works of Scott May being referenced
A Titin mutation defines roles for circulation in endothelial morphogenesis
2004
A Focused and Efficient Genetic Screening Strategy in the Mouse: Identification of Mutations That Disrupt Cortical Development
2004
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
2005
A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice
2010
Retinoic Acid from the Meninges Regulates Cortical Neuron Generation
2009
The Rfx4 Transcription Factor Modulates Shh Signaling by Regional Control of Ciliogenesis
2009
Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development
2007